Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

Objective:To grasp the degree of coordinated development and spatial distribution characteristics of medical service prices,medical service capacity and regional economic level,so as to promote the benign and coordinated development of medical service prices and various systems.Methods:The entropy value method is used to calculate the comprehensive evaluation index of medical service price,medical service capacity and regional economic level in the sample provinces,and the coupling coordination degree model is used to analyze the degree of coupling coordination between medical service price,medical service capacity and regional economic level in the sample provinces,and carry out spatial autocorrelation analysis.Results:The price of medical services was moderately coupled to the capacity of medical services and the level of the regional economy,and there was moderate dependence between the systems;the price of medical services was poorly coordinated with the capacity of medical services and the level of the regional economy;the coordination between the current price of medical services in China and the capacity of medical services and the level of the regional economy did not have a spatial aggregation and radiation effect in space.Conclusion:Coordination between the price of medical services in China and the capacity of medical services and regional economic level needed to be strengthened urgently.Suggestion:The capacity of medical services should be quantitatively evaluated and the formation of medical service prices should be guided,the coordination and linkage between medical service prices and macroeconomic levels should be strengthened,and efforts should be made to enhance the regional equilibrium of China's medical service price policy.

This investigation was conducted on clinical professional graduate students of Chongqing Medical University to analyze the problems and influencing factors in the process of scientific research ability training. We propose three measures to improve the model of training professional clinical graduate students and provide references for the cultivation of their scientific research ability. The measures are "clear orientation of clinical scientific research ability training", "constant pursuit of high-level original scientific research results" and "adherent implementation to strengthen training effect".

Objective :To explore influence of ticagrelor combined percutaneous coronary intervention (PCI) on myo‐cardial perfusion ,serum levels of platelet activating factor (PAF) and activated platelet membrane glycoprotein Ⅱb／Ⅲa complex (PAC‐1) in patients with acute myocardial infarction (AMI ).Methods :A total of 120 AMI patients undergoing emergency PCI were selected , randomly and equally divided into clopidogrel combined aspirin group (control group) and ticagrelor combined aspirin group (T+ A group).Perfusion indexes ,cardiac function indexes and serum levels of PAF and PAC‐1 were measured and compared between two groups on 24h and six months after PCI ,and incidence of adverse events within six‐month was recorded .Results :After PCI ,there was no significant difference in TIMI grade 3 blood flow rate between two groups , P＝0.488. Compared with control group on six months after PCI ,there were significant rise in cardiac index [ (2.61 ± 1.31) L·min－1 ·m－2 vs.(3. 12 ± 1.37) L ·min－1 ·m－2 ] ,stroke volume [ (60.99 ± 5.13) ml vs.(71. 24 ± 5. 94) ml] and left ventricular ejection fraction [ (45.31 ± 6. 73 )% vs.(72.64 ± 7.29 )%] , and significant reductions in left ventricular end‐systolic dimension [ (59.41 ± 4. 12) mm vs.(53.12 ± 3.45) mm] ,serum levels of PAF [ (10. 31 ± 1. 69) μg／L vs .(8.26 ± 1.38) μg／L] and PAC‐1 [ (37.57 ± 5.74)% vs.(32.14 ± 4.93)%] in T+A group , P＜0. 05 or ＜0.01. During six‐month follow‐up ,no patient died in either group ,and incidence rate of adverse events in T+A group was significantly low‐er than that of control group (1. 67% vs.11.67%, P＝0. 028 ).Conclusion :Ticagrelor combined PCI can signifi‐cantly improve cardiac function and reduce peripheral blood levels of PAF and PAC‐1 with good safety in AMI pa‐tients .It′s worth clinical extension and application .