1.Predictive value and optimal cut-off level of high-sensitivity troponin T in patients with acute pulmonary embolism
Moojun KIM ; Chang-Ok SEO ; Yong-Lee KIM ; Hangyul KIM ; Hye Ree KIM ; Yun Ho CHO ; Jeong Yoon JANG ; Jong-Hwa AHN ; Min Gyu KANG ; Kyehwan KIM ; Jin-Sin KOH ; Seok-Jae HWANG ; Jin Yong HWANG ; Jeong Rang PARK
The Korean Journal of Internal Medicine 2025;40(1):65-77
		                        		
		                        			 Background/Aims:
		                        			Elevated troponin levels predict in-hospital mortality and influence decisions regarding thrombolytic therapy in patients with acute pulmonary embolism (PE). However, the usefulness of high-sensitivity troponin T (hsTnT) regarding PE remains uncertain. We aimed to establish the optimal cut-off level and compare its performance for precise risk stratification. 
		                        		
		                        			Methods:
		                        			374 patients diagnosed with acute PE were reviewed. PE-related adverse outcomes, a composite of PE-related deaths, cardiopulmonary resuscitation incidents, systolic blood pressure < 90 mmHg, and all-cause mortality within 30 days were evaluated. The optimal hsTnT cut-off for all-cause mortality, and the net reclassification index (NRI) was used to assess the incremental value in risk stratification. 
		                        		
		                        			Results:
		                        			Among 343 normotensive patients, 17 (5.0%) experienced all-cause mortality, while 40 (10.7%) had PE-related adverse outcomes. An optimal hsTnT cut-off value of 60 ng/L for all-cause mortality (AUC 0.74, 95% CI 0.61–0.85, p < 0.001) was identified, which was significantly associated with PE-related adverse outcomes (OR 4.07, 95% CI 2.06–8.06, p < 0.001). Patients with hsTnT ≥ 60 ng/L were older, hypotensive, had higher creatinine levels, and right ventricular dysfunction signs. Combining hsTnT ≥ 60 ng/L with simplified pulmonary embolism severity index ≥1 provided additional prognostic information. Reclassification analysis showed a significant shift in risk categories, with an NRI of 1.016 ± 0.201 (p < 0.001). 
		                        		
		                        			Conclusions
		                        			We refined troponin’s predictive value in patients with acute PE, proposing a new cut-off value of hsTnT ≥ 60 ng/L. Validation through large-scale studies is essential to offer clinically useful guidance for managing patient population. 
		                        		
		                        		
		                        		
		                        	
2.Predictive value and optimal cut-off level of high-sensitivity troponin T in patients with acute pulmonary embolism
Moojun KIM ; Chang-Ok SEO ; Yong-Lee KIM ; Hangyul KIM ; Hye Ree KIM ; Yun Ho CHO ; Jeong Yoon JANG ; Jong-Hwa AHN ; Min Gyu KANG ; Kyehwan KIM ; Jin-Sin KOH ; Seok-Jae HWANG ; Jin Yong HWANG ; Jeong Rang PARK
The Korean Journal of Internal Medicine 2025;40(1):65-77
		                        		
		                        			 Background/Aims:
		                        			Elevated troponin levels predict in-hospital mortality and influence decisions regarding thrombolytic therapy in patients with acute pulmonary embolism (PE). However, the usefulness of high-sensitivity troponin T (hsTnT) regarding PE remains uncertain. We aimed to establish the optimal cut-off level and compare its performance for precise risk stratification. 
		                        		
		                        			Methods:
		                        			374 patients diagnosed with acute PE were reviewed. PE-related adverse outcomes, a composite of PE-related deaths, cardiopulmonary resuscitation incidents, systolic blood pressure < 90 mmHg, and all-cause mortality within 30 days were evaluated. The optimal hsTnT cut-off for all-cause mortality, and the net reclassification index (NRI) was used to assess the incremental value in risk stratification. 
		                        		
		                        			Results:
		                        			Among 343 normotensive patients, 17 (5.0%) experienced all-cause mortality, while 40 (10.7%) had PE-related adverse outcomes. An optimal hsTnT cut-off value of 60 ng/L for all-cause mortality (AUC 0.74, 95% CI 0.61–0.85, p < 0.001) was identified, which was significantly associated with PE-related adverse outcomes (OR 4.07, 95% CI 2.06–8.06, p < 0.001). Patients with hsTnT ≥ 60 ng/L were older, hypotensive, had higher creatinine levels, and right ventricular dysfunction signs. Combining hsTnT ≥ 60 ng/L with simplified pulmonary embolism severity index ≥1 provided additional prognostic information. Reclassification analysis showed a significant shift in risk categories, with an NRI of 1.016 ± 0.201 (p < 0.001). 
		                        		
		                        			Conclusions
		                        			We refined troponin’s predictive value in patients with acute PE, proposing a new cut-off value of hsTnT ≥ 60 ng/L. Validation through large-scale studies is essential to offer clinically useful guidance for managing patient population. 
		                        		
		                        		
		                        		
		                        	
3.Predictive value and optimal cut-off level of high-sensitivity troponin T in patients with acute pulmonary embolism
Moojun KIM ; Chang-Ok SEO ; Yong-Lee KIM ; Hangyul KIM ; Hye Ree KIM ; Yun Ho CHO ; Jeong Yoon JANG ; Jong-Hwa AHN ; Min Gyu KANG ; Kyehwan KIM ; Jin-Sin KOH ; Seok-Jae HWANG ; Jin Yong HWANG ; Jeong Rang PARK
The Korean Journal of Internal Medicine 2025;40(1):65-77
		                        		
		                        			 Background/Aims:
		                        			Elevated troponin levels predict in-hospital mortality and influence decisions regarding thrombolytic therapy in patients with acute pulmonary embolism (PE). However, the usefulness of high-sensitivity troponin T (hsTnT) regarding PE remains uncertain. We aimed to establish the optimal cut-off level and compare its performance for precise risk stratification. 
		                        		
		                        			Methods:
		                        			374 patients diagnosed with acute PE were reviewed. PE-related adverse outcomes, a composite of PE-related deaths, cardiopulmonary resuscitation incidents, systolic blood pressure < 90 mmHg, and all-cause mortality within 30 days were evaluated. The optimal hsTnT cut-off for all-cause mortality, and the net reclassification index (NRI) was used to assess the incremental value in risk stratification. 
		                        		
		                        			Results:
		                        			Among 343 normotensive patients, 17 (5.0%) experienced all-cause mortality, while 40 (10.7%) had PE-related adverse outcomes. An optimal hsTnT cut-off value of 60 ng/L for all-cause mortality (AUC 0.74, 95% CI 0.61–0.85, p < 0.001) was identified, which was significantly associated with PE-related adverse outcomes (OR 4.07, 95% CI 2.06–8.06, p < 0.001). Patients with hsTnT ≥ 60 ng/L were older, hypotensive, had higher creatinine levels, and right ventricular dysfunction signs. Combining hsTnT ≥ 60 ng/L with simplified pulmonary embolism severity index ≥1 provided additional prognostic information. Reclassification analysis showed a significant shift in risk categories, with an NRI of 1.016 ± 0.201 (p < 0.001). 
		                        		
		                        			Conclusions
		                        			We refined troponin’s predictive value in patients with acute PE, proposing a new cut-off value of hsTnT ≥ 60 ng/L. Validation through large-scale studies is essential to offer clinically useful guidance for managing patient population. 
		                        		
		                        		
		                        		
		                        	
4.Predictive value and optimal cut-off level of high-sensitivity troponin T in patients with acute pulmonary embolism
Moojun KIM ; Chang-Ok SEO ; Yong-Lee KIM ; Hangyul KIM ; Hye Ree KIM ; Yun Ho CHO ; Jeong Yoon JANG ; Jong-Hwa AHN ; Min Gyu KANG ; Kyehwan KIM ; Jin-Sin KOH ; Seok-Jae HWANG ; Jin Yong HWANG ; Jeong Rang PARK
The Korean Journal of Internal Medicine 2025;40(1):65-77
		                        		
		                        			 Background/Aims:
		                        			Elevated troponin levels predict in-hospital mortality and influence decisions regarding thrombolytic therapy in patients with acute pulmonary embolism (PE). However, the usefulness of high-sensitivity troponin T (hsTnT) regarding PE remains uncertain. We aimed to establish the optimal cut-off level and compare its performance for precise risk stratification. 
		                        		
		                        			Methods:
		                        			374 patients diagnosed with acute PE were reviewed. PE-related adverse outcomes, a composite of PE-related deaths, cardiopulmonary resuscitation incidents, systolic blood pressure < 90 mmHg, and all-cause mortality within 30 days were evaluated. The optimal hsTnT cut-off for all-cause mortality, and the net reclassification index (NRI) was used to assess the incremental value in risk stratification. 
		                        		
		                        			Results:
		                        			Among 343 normotensive patients, 17 (5.0%) experienced all-cause mortality, while 40 (10.7%) had PE-related adverse outcomes. An optimal hsTnT cut-off value of 60 ng/L for all-cause mortality (AUC 0.74, 95% CI 0.61–0.85, p < 0.001) was identified, which was significantly associated with PE-related adverse outcomes (OR 4.07, 95% CI 2.06–8.06, p < 0.001). Patients with hsTnT ≥ 60 ng/L were older, hypotensive, had higher creatinine levels, and right ventricular dysfunction signs. Combining hsTnT ≥ 60 ng/L with simplified pulmonary embolism severity index ≥1 provided additional prognostic information. Reclassification analysis showed a significant shift in risk categories, with an NRI of 1.016 ± 0.201 (p < 0.001). 
		                        		
		                        			Conclusions
		                        			We refined troponin’s predictive value in patients with acute PE, proposing a new cut-off value of hsTnT ≥ 60 ng/L. Validation through large-scale studies is essential to offer clinically useful guidance for managing patient population. 
		                        		
		                        		
		                        		
		                        	
5.Predictive value and optimal cut-off level of high-sensitivity troponin T in patients with acute pulmonary embolism
Moojun KIM ; Chang-Ok SEO ; Yong-Lee KIM ; Hangyul KIM ; Hye Ree KIM ; Yun Ho CHO ; Jeong Yoon JANG ; Jong-Hwa AHN ; Min Gyu KANG ; Kyehwan KIM ; Jin-Sin KOH ; Seok-Jae HWANG ; Jin Yong HWANG ; Jeong Rang PARK
The Korean Journal of Internal Medicine 2025;40(1):65-77
		                        		
		                        			 Background/Aims:
		                        			Elevated troponin levels predict in-hospital mortality and influence decisions regarding thrombolytic therapy in patients with acute pulmonary embolism (PE). However, the usefulness of high-sensitivity troponin T (hsTnT) regarding PE remains uncertain. We aimed to establish the optimal cut-off level and compare its performance for precise risk stratification. 
		                        		
		                        			Methods:
		                        			374 patients diagnosed with acute PE were reviewed. PE-related adverse outcomes, a composite of PE-related deaths, cardiopulmonary resuscitation incidents, systolic blood pressure < 90 mmHg, and all-cause mortality within 30 days were evaluated. The optimal hsTnT cut-off for all-cause mortality, and the net reclassification index (NRI) was used to assess the incremental value in risk stratification. 
		                        		
		                        			Results:
		                        			Among 343 normotensive patients, 17 (5.0%) experienced all-cause mortality, while 40 (10.7%) had PE-related adverse outcomes. An optimal hsTnT cut-off value of 60 ng/L for all-cause mortality (AUC 0.74, 95% CI 0.61–0.85, p < 0.001) was identified, which was significantly associated with PE-related adverse outcomes (OR 4.07, 95% CI 2.06–8.06, p < 0.001). Patients with hsTnT ≥ 60 ng/L were older, hypotensive, had higher creatinine levels, and right ventricular dysfunction signs. Combining hsTnT ≥ 60 ng/L with simplified pulmonary embolism severity index ≥1 provided additional prognostic information. Reclassification analysis showed a significant shift in risk categories, with an NRI of 1.016 ± 0.201 (p < 0.001). 
		                        		
		                        			Conclusions
		                        			We refined troponin’s predictive value in patients with acute PE, proposing a new cut-off value of hsTnT ≥ 60 ng/L. Validation through large-scale studies is essential to offer clinically useful guidance for managing patient population. 
		                        		
		                        		
		                        		
		                        	
6.Erratum to: Corrigendum: 2023 Korean Society of Menopause -Osteoporosis Guidelines Part I
Dong Ock LEE ; Yeon Hee HONG ; Moon Kyoung CHO ; Young Sik CHOI ; Sungwook CHUN ; Youn-Jee CHUNG ; Seung Hwa HONG ; Kyu Ri HWANG ; Jinju KIM ; Hoon KIM ; Dong-Yun LEE ; Sa Ra LEE ; Hyun-Tae PARK ; Seok Kyo SEO ; Jung-Ho SHIN ; Jae Yen SONG ; Kyong Wook YI ; Haerin PAIK ; Ji Young LEE
Journal of Menopausal Medicine 2024;30(3):179-179
		                        		
		                        		
		                        		
		                        	
7.A Study on the Behavior, Problems, and Countermeasures of Cosmetic General Practitioners Impersonating Dermatologists in Korea
Kyung-Hwa NAM ; Geon-Jong LEE ; Tae-Jong KANG ; Hyun-Ji RYU ; Jin PARK ; Seok-Kweon YUN
Korean Journal of Dermatology 2024;62(9):503-509
		                        		
		                        			 Background:
		                        			The number of general cosmetic practitioners impersonating dermatologists in Korea has increased, leading to serious harm that is significant enough to attract the attention of health authorities, which dermatologists are deeply concerned about. 
		                        		
		                        			Objective:
		                        			We conducted a survey targeting dermatologists to gather their opinions on the behavior, problems, and countermeasures of general cosmetic practitioners disguising themselves as dermatologists. 
		                        		
		                        			Methods:
		                        			A total of 280 dermatologists completed the survey between January and February 2024. The questions covered demographic characteristics, experiences of cosmetic general practitioners falsely introduced themselves as dermatologists, complications experienced by patients who received treatment after being mistaken for a dermatologist, the seriousness of the problem for cosmetic general practitioners impersonating dermatologists, and the relationship between the shortage of essential medical personnel and the phenomenon of cosmetic general practitioners disguising themselves as dermatologists. 
		                        		
		                        			Results:
		                        			Despite cases in which cosmetic general practitioners impersonate dermatologists, most dermatologists have not responded appropriately in many instances. Dermatologists have reported many cases of complications after receiving dermatological treatment from such cosmetic general practitioners. Most dermatologists are concerned about the serious problems of general cosmetic practitioners, disguising themselves as dermatologists and anticipating many adverse effects. 
		                        		
		                        			Conclusion
		                        			We believe that we need to pool our wisdom to solve these problems and expect that this study will provide valuable basic data for solving these problems in the dermatology and medical environments of Korea. 
		                        		
		                        		
		                        		
		                        	
8.A Study on the Behavior, Problems, and Countermeasures of Cosmetic General Practitioners Impersonating Dermatologists in Korea
Kyung-Hwa NAM ; Geon-Jong LEE ; Tae-Jong KANG ; Hyun-Ji RYU ; Jin PARK ; Seok-Kweon YUN
Korean Journal of Dermatology 2024;62(9):503-509
		                        		
		                        			 Background:
		                        			The number of general cosmetic practitioners impersonating dermatologists in Korea has increased, leading to serious harm that is significant enough to attract the attention of health authorities, which dermatologists are deeply concerned about. 
		                        		
		                        			Objective:
		                        			We conducted a survey targeting dermatologists to gather their opinions on the behavior, problems, and countermeasures of general cosmetic practitioners disguising themselves as dermatologists. 
		                        		
		                        			Methods:
		                        			A total of 280 dermatologists completed the survey between January and February 2024. The questions covered demographic characteristics, experiences of cosmetic general practitioners falsely introduced themselves as dermatologists, complications experienced by patients who received treatment after being mistaken for a dermatologist, the seriousness of the problem for cosmetic general practitioners impersonating dermatologists, and the relationship between the shortage of essential medical personnel and the phenomenon of cosmetic general practitioners disguising themselves as dermatologists. 
		                        		
		                        			Results:
		                        			Despite cases in which cosmetic general practitioners impersonate dermatologists, most dermatologists have not responded appropriately in many instances. Dermatologists have reported many cases of complications after receiving dermatological treatment from such cosmetic general practitioners. Most dermatologists are concerned about the serious problems of general cosmetic practitioners, disguising themselves as dermatologists and anticipating many adverse effects. 
		                        		
		                        			Conclusion
		                        			We believe that we need to pool our wisdom to solve these problems and expect that this study will provide valuable basic data for solving these problems in the dermatology and medical environments of Korea. 
		                        		
		                        		
		                        		
		                        	
9.Erratum to: Corrigendum: 2023 Korean Society of Menopause -Osteoporosis Guidelines Part I
Dong Ock LEE ; Yeon Hee HONG ; Moon Kyoung CHO ; Young Sik CHOI ; Sungwook CHUN ; Youn-Jee CHUNG ; Seung Hwa HONG ; Kyu Ri HWANG ; Jinju KIM ; Hoon KIM ; Dong-Yun LEE ; Sa Ra LEE ; Hyun-Tae PARK ; Seok Kyo SEO ; Jung-Ho SHIN ; Jae Yen SONG ; Kyong Wook YI ; Haerin PAIK ; Ji Young LEE
Journal of Menopausal Medicine 2024;30(3):179-179
		                        		
		                        		
		                        		
		                        	
10.A Study on the Behavior, Problems, and Countermeasures of Cosmetic General Practitioners Impersonating Dermatologists in Korea
Kyung-Hwa NAM ; Geon-Jong LEE ; Tae-Jong KANG ; Hyun-Ji RYU ; Jin PARK ; Seok-Kweon YUN
Korean Journal of Dermatology 2024;62(9):503-509
		                        		
		                        			 Background:
		                        			The number of general cosmetic practitioners impersonating dermatologists in Korea has increased, leading to serious harm that is significant enough to attract the attention of health authorities, which dermatologists are deeply concerned about. 
		                        		
		                        			Objective:
		                        			We conducted a survey targeting dermatologists to gather their opinions on the behavior, problems, and countermeasures of general cosmetic practitioners disguising themselves as dermatologists. 
		                        		
		                        			Methods:
		                        			A total of 280 dermatologists completed the survey between January and February 2024. The questions covered demographic characteristics, experiences of cosmetic general practitioners falsely introduced themselves as dermatologists, complications experienced by patients who received treatment after being mistaken for a dermatologist, the seriousness of the problem for cosmetic general practitioners impersonating dermatologists, and the relationship between the shortage of essential medical personnel and the phenomenon of cosmetic general practitioners disguising themselves as dermatologists. 
		                        		
		                        			Results:
		                        			Despite cases in which cosmetic general practitioners impersonate dermatologists, most dermatologists have not responded appropriately in many instances. Dermatologists have reported many cases of complications after receiving dermatological treatment from such cosmetic general practitioners. Most dermatologists are concerned about the serious problems of general cosmetic practitioners, disguising themselves as dermatologists and anticipating many adverse effects. 
		                        		
		                        			Conclusion
		                        			We believe that we need to pool our wisdom to solve these problems and expect that this study will provide valuable basic data for solving these problems in the dermatology and medical environments of Korea. 
		                        		
		                        		
		                        		
		                        	
            
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