1.Distant migration of copolyamide breast filler following mammography: a case report
Hyeon Min YOON ; Woo Jin SONG ; Chan Yeong LEE ; Sang Gue KANG
Archives of Aesthetic Plastic Surgery 2024;30(1):39-42
		                        		
		                        			
		                        			 Copolyamide fillers, such as Aquafilling, have been used off-label for breast augmentation in many countries, including Korea. However, safety concerns have arisen due to reported complications, including induration, masses, mastalgia, firmness, asymmetry, migration, infection, and dimpling. We report the case of a 33-year-old woman who presented with distant migration of copolyamide breast filler to the left lower abdomen and inguinal area following mammography for breast cancer screening. This case highlights the potential risks associated with the migration of copolyamide breast fillers, particularly in the context of cancer screening procedures, and emphasizes the importance of awareness and vigilance among clinicians and patients. 
		                        		
		                        		
		                        		
		                        	
2.Efficacy of ultrasonic cavitation in isolation of the stromal vascular fraction from adipose tissue
Syeo Young WEE ; Jeong Do PARK ; Sang Gue KANG ; Eun Soo PARK
Archives of Aesthetic Plastic Surgery 2024;30(1):16-21
		                        		
		                        			 Background:
		                        			Adipose tissue-derived stem cells (ASCs) represent a rapidly evolving area of cell-based therapies. ASCs are harvested from the stromal vascular fraction (SVF), a heterogeneous mixture of ASCs and other cell types. Two methods are typically employed to obtain the SVF: enzymatic and mechanical. In this study, we examined the efficacy of ultrasonic cavitation in isolating the SVF from adipose tissue. 
		                        		
		                        			Methods:
		                        			Human adipose tissue was procured from three patients through an aesthetic liposuction procedure. This tissue was then subjected to either an enzymatic method utilizing type II collagenase or an ultrasonic cavitation method using an Ultra Stemcell device. The cell counts and viability were determined using a cell counter. The immunophenotype of the SVF was analyzed using real-time polymerase chain reaction. 
		                        		
		                        			Results:
		                        			Compared to the enzymatic method, the total cell count and cell viability of the SVF isolated through ultrasonic cavitation were relatively low. However, no significant difference was observed in the immunophenotype of CD45, CD11b, CD34, and CD105. 
		                        		
		                        			Conclusions
		                        			The ultrasonic cavitation method constitutes a clinically practical approach that offers straightforward access in the operative field. This technique is a rapid and cost-effective method for isolating the SVF. 
		                        		
		                        		
		                        		
		                        	
3.Complications and management of breast augmentation using two different types of fillers: a case series
Woo Jung CHOI ; Woo Jin SONG ; Sang Gue KANG
Archives of Aesthetic Plastic Surgery 2023;29(1):41-45
		                        		
		                        			
		                        			 An advantage of breast augmentation with injectable fillers is that the desired size can be determined and achieved under local anesthesia with a short recovery time. However, a high complication rate is a critical disadvantage. Some fillers are challenging to remove, resulting in breast deformity and scarring. Five patients who underwent surgery to manage a foreign body in the breasts in 2021 were enrolled in this study. Two had copolyamide filler injections, while the other three had polyacrylamide hydrogel filler injections. A physical examination was performed, and preoperative and intraoperative photographs were obtained. Two patients underwent subcutaneous mastectomy because most of the filler had infiltrated into the normal breast tissue. In contrast, the other patients underwent filler removal and debridement because most of the filler had remained separate from the normal breast tissue. All patients who had a subcutaneous mastectomy and one who underwent only filler removal underwent immediate breast reconstruction with cohesive gel implants. The other patients rejected immediate reconstruction, and only filler removal was performed. All patients recovered without complications. We propose an algorithm for diagnosis and treatment based on our cases, which we hope can help clinicians manage the complications of filler injections for breast augmentation. 
		                        		
		                        		
		                        		
		                        	
4.Initial experiences and usefulness of porcine acellular dermal matrix-assisted prepectoral breast implant surgery: a case series and systematic review
Chan Yeong LEE ; Woo Jin SONG ; Hyung Bo SIM ; Hyun Gyo JEONG ; Sang Gue KANG
Archives of Aesthetic Plastic Surgery 2023;29(2):76-88
		                        		
		                        			 Background:
		                        			We report our experiences with prepectoral placement breast implant surgery using Supporix (HansBioMed), a porcine acellular dermal matrix (PADM), for cosmetic and reconstructive indications. The clinical efficiency, safety, and cost-effectiveness of PADM were also discussed. 
		                        		
		                        			Methods:
		                        			A single-center, retrospective study was designed from December 2017 to December 2019. The participants were Korean women who underwent PADM-assisted prepectoral breast implant surgery performed by two surgeons. All complications were registered and analyzed. A systematic review and meta-analysis of complication rates after PADM-assisted prepectoral breast implant surgery were conducted for comparison with other studies. A subgroup analysis was performed according to the operation type: the cosmetic breast surgery (CBS) group, the immediate implant-based breast reconstruction (IIBR) group, and the delayed implant-based breast reconstruction (DIBR) group. 
		                        		
		                        			Results:
		                        			Twenty breasts in 16 patients were included in our study (median follow-up period, 8.25 months). In a systematic review, 20 publications with a total of 2,504 breasts in 1,921 women were quantitively analyzed. The overall complication rates in our study and other studies were 14% and 24% in the total group analysis, 0% and 12% in the CBS group, 62% and 26% in the IIBR group, and 0% and 28% in the DIBR group, respectively. 
		                        		
		                        			Conclusions
		                        			Our data support the effectiveness of PADM-assisted prepectoral breast implant surgery, which was comparable to other studies. PADM was effective for reducing seroma and hematoma in the revision CBS group and the DIBR group. In the IIBR group, it was helpful in preventing implant loss and explantation. 
		                        		
		                        		
		                        		
		                        	
5.The impact of Allergan implant-related issues on patients with breast implants for reconstruction
Ji Min KIM ; Woo Jin SONG ; Hyun Gyo JEONG ; Sang Gue KANG
Archives of Aesthetic Plastic Surgery 2021;27(4):132-138
		                        		
		                        			 Background:
		                        			In August 2019, the Ministry of Food and Drug Safety and the Korean Society of Plastic and Reconstructive Surgeons confirmed the first case report of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) in Korea and provided recommendations. This study was conducted to evaluate the impact of the first case report of BIA-ALCL on patients and whether the impact could be mitigated through expert recommendations. 
		                        		
		                        			Methods:
		                        			A retrospective chart review was performed of patients who underwent implant-based breast reconstruction using Biocell textured breast implants at Soonchunhyang University Hospital. After the first case report of BIA-ALCL and informing the patients via text messages, the pattern of outpatient visits and the proportion and indications of outpatient office visitors who received reoperations were analyzed. 
		                        		
		                        			Results:
		                        			After the first BIA-ALCL case report in Korea, 12 patients underwent reoperations due to other complications identified incidentally, while only three patients underwent prophylactic surgery. Among the patients who underwent reoperation after the Allergan issues, 76.7% received implant exchange. There was no significant difference in the proportion of reoperation types before and after the Allergan issues and the transmission of text messages (P=0.700). 
		                        		
		                        			Conclusions
		                        			Despite the major issues, outpatients were managed successfully according to our recommendations. The study found a low rate of regular outpatient visits; however, our efforts increased this rate. Therefore, methods for appropriate information delivery are needed for outpatient visits, as well as a system for regular monitoring. As experts, plastic surgeons should provide responsible leadership in this situation to relieve patients’ concerns. 
		                        		
		                        		
		                        		
		                        	
7.New strategy to prevent implant displacement in transaxillary endoscopic augmentation mammaplasty
Sang-Gue KANG ; Joung-Ki KIM ; Soon Chan UM
Archives of Aesthetic Plastic Surgery 2020;26(1):41-45
		                        		
		                        			
		                        			 Breast augmentation is one of the most popular cosmetic procedures in Korea and worldwide. In breast augmentation, it is crucial to place the implant in the proper position by creating an adequate pocket considering the size of the implant. This prevents subsequent displacement of the implant. When using an endoscope, the operation is performed without direct vision and in a narrow surgical space, leading to limitations in practice. Inexperienced physicians face a steep learning curve in their efforts to overcome this difficulty. In this study, we attempted to overcome this challenge by specifying the medial and lateral dissection ranges. The extent of the dissection is determined based on the pinnate of the pectoralis major muscle when dissecting medially and the fascia of the pectoralis major, the pectoralis minor, and the serratus anterior muscles when dissecting laterally. In addition, the structure made from the medial and lateral sides can support the implant like a funnel and can prevent further downward, inward, and outward displacement. 
		                        		
		                        		
		                        		
		                        	
8.Current status of and trends in post-mastectomy breast reconstruction in Korea
Woo Jin SONG ; Sang Gue KANG ; Eun Key KIM ; Seung Yong SONG ; Joon Seok LEE ; Jung Ho LEE ; Ung Sik JIN
Archives of Plastic Surgery 2020;47(2):118-125
		                        		
		                        			
		                        			 Since April 2015, post-mastectomy breast reconstruction has been covered by the Korean National Health Insurance Service (NHIS). The frequency of these procedures has increased very rapidly. We analyzed data obtained from the Big Data Hub of the Health Insurance Review and Assessment Service (HIRA) and determined annual changes in the number of breast reconstruction procedures and related trends in Korea. We evaluated the numbers of mastectomy and breast reconstruction procedures performed between April 2015 and December 2018 using data from the HIRA Big Data Hub. We determined annual changes in the numbers of total, autologous, and implant breast reconstructions after NHIS coverage commenced. Data were analyzed using Microsoft Excel. The post-mastectomy breast reconstruction rate increased from 19.4% in 2015 to 53.4% in 2018. In 2015, implant reconstruction was performed in 1,366 cases and autologous reconstruction in 905 (60.1% and 39.8%, respectively); these figures increased to 3,703 and 1,570 (70.2% and 29.7%, respectively) in 2018. Free tissue transfer and deep inferior epigastric perforator flap creation were the most common autologous reconstruction procedures. For implant-based reconstructions, the rates of directto-implant and tissue-expander breast reconstructions (first stage) were similar in 2018. This study summarizes breast reconstruction trends in Korea after NHIS coverage was expanded in 2015. A significant increase over time in the post-mastectomy breast reconstruction rate was evident, with a trend toward implant-based reconstruction. Analysis of data from the HIRA Big Data Hub can be used to predict breast reconstruction trends and convey precise information to patients and physicians. 
		                        		
		                        		
		                        		
		                        	
9.Emergency room visits for severe complications after cosmetic surgery
Wang Seok LEE ; Si Hyun PARK ; Sang Gue KANG ; Min Sung TAK ; Chul Han KIM ; Sang Won LEE
Archives of Aesthetic Plastic Surgery 2019;25(3):108-114
		                        		
		                        			
		                        			BACKGROUND: Because many cosmetic surgery clinics are not adequately equipped to handle emergent conditions, patients often come to a university hospital when problems occur during or after cosmetic surgery. However, few in-depth studies have been conducted of this issue. Therefore, we investigated emergency department visits due to complications associated with cosmetic surgery. METHODS: A retrospective chart review was conducted of 38 patients who visited the emergency department of the authors' institution due to complications associated with cosmetic surgery from July 2014 to June 2017. RESULTS: There were more women than men (30 women vs. 8 men). Their mean age was 32.4 years (range, 19–57 years). Upon presentation to the emergency department, patients' vital signs and mental status were usually normal (27 normal vs. 11 abnormal). The types of surgery included blepharoplasty, rhinoplasty, malar/orthognathic surgery, mammaplasty, liposuction, fat grafting, and filler and botulinum toxin injections. Most patients required hospitalization (26 admitted vs. 12 discharged). Eight of the hospitalized patients required intensive care unit care, of whom two died and three experienced brain death or had permanent neurologic sequelae. CONCLUSIONS: The complications were usually minor problems, despite the need for hospitalization, but some complications were life-threatening. We recommend close monitoring and maintaining an adequate injection capacity for intravenous sedative anesthesia. When any symptom or sign of a complication occurs, it is best to transfer the patient to a university hospital as soon as possible. Taking a careful medical history is always needed, even for minor procedures.
		                        		
		                        		
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Blepharoplasty
		                        			;
		                        		
		                        			Botulinum Toxins
		                        			;
		                        		
		                        			Brain Death
		                        			;
		                        		
		                        			Cardiomyopathies
		                        			;
		                        		
		                        			Emergencies
		                        			;
		                        		
		                        			Emergency Service, Hospital
		                        			;
		                        		
		                        			Epinephrine
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Hospitalization
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intensive Care Units
		                        			;
		                        		
		                        			Lipectomy
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Mammaplasty
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Rhinoplasty
		                        			;
		                        		
		                        			Surgery, Plastic
		                        			;
		                        		
		                        			Transplants
		                        			;
		                        		
		                        			Vital Signs
		                        			
		                        		
		                        	
10.A 30-year neglected foreign body mimicking a maxillary fracture
Wang Seok LEE ; Eun Soo PARK ; Sang Gue KANG ; Min Sung TAK ; Chul Han KIM
Archives of Craniofacial Surgery 2019;20(3):195-198
		                        		
		                        			
		                        			A-50-year-old male patient presented with complaint of tenderness on the left malar area after traffic accident. Our first impression on him was zygomatic fracture, we did radiologic work-up and physical examination on him. But, on the computed tomography scan, there was no fracture or discontinuity on his facial bone. The computed tomography scan was revealed a 4-cm long foreign body in left maxillary sinus with a large amount of fluid collection. After thorough history taking from him, we reveal the patient had a history of trauma 30 years back on the left zygomatic area with a chopstick. The foreign body was removed via transoral approach with the endoscopic assist. There was no complication after operation.
		                        		
		                        		
		                        		
		                        			Accidents, Traffic
		                        			;
		                        		
		                        			Facial Bones
		                        			;
		                        		
		                        			Foreign Bodies
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Maxilla
		                        			;
		                        		
		                        			Maxillary Fractures
		                        			;
		                        		
		                        			Maxillary Sinus
		                        			;
		                        		
		                        			Physical Examination
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Zygomatic Fractures
		                        			
		                        		
		                        	
            
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