1.Prevalence and Predictors of Pulmonary Hypertension in Children with Portal Hypertension: A Single Center Study
Nehal El KOOFY ; Sawsan Hassan OKASHA ; Hala Mounir AGHA ; Noha ALI ; Ahmed Said BEHAIRY ; Hanan Mina FOUAD ; Rehab Hamdy ZAWAM
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):101-112
		                        		
		                        			 Purpose:
		                        			This study aimed to estimate the prevalence and predictors of portopulmonary hypertension (POPH) in children with portal hypertension. 
		                        		
		                        			Methods:
		                        			We recruited children of both sexes aged 3–15 years with portal hypertension that was clinically suspected and confirmed by the presence of varices on esophagogastroduodenoscopy (EGD). The participants underwent clinical examination, 6-min walk distance (6-MWD), and echocardiography. 
		                        		
		                        			Results:
		                        			We enrolled 94 children with portal hypertension: 26.6% with pre-hepatic causes and 73.4% secondary to chronic liver disease. Among our participants, 13.8% had one or more cardiac manifestations, such as exercise intolerance, dyspnea on exertion, cyanosis, or orthopnea, whereas 86.2% were asymptomatic. EGD examination revealed grade I varices in 54.3% of cases, grade II–III in 43.6%, and grade IV in 2.1%. Pulmonary hypertension (>35 mmHg) was detected in 30.9% of cases using echocardiography; two of them were >45 mmHg. Patients with POPH had significantly more frequent dyspnea on exertion, lower O 2 saturation, and more severe variceal grades than those with normal pulmonary artery pressure. Five (6.9%) cases had <300 m 6-MWD, with no significant difference between patients with normal and those with elevated pulmonary artery pressure. The duration of portal hypertension and 6-MWD were correlated significantly with the echocardiographic measures. High-grade varices (p=0.04) and low O 2 saturation (p=0.03) were identified as risk factors for POPH. 
		                        		
		                        			Conclusion
		                        			POPH was detected in 30.9% of our study group. High-grade varices and low O 2 saturation are predictors of POPH. Echocardiography screening is crucial for the early detection of cases. 
		                        		
		                        		
		                        		
		                        	
2.Prevalence and Predictors of Pulmonary Hypertension in Children with Portal Hypertension: A Single Center Study
Nehal El KOOFY ; Sawsan Hassan OKASHA ; Hala Mounir AGHA ; Noha ALI ; Ahmed Said BEHAIRY ; Hanan Mina FOUAD ; Rehab Hamdy ZAWAM
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):101-112
		                        		
		                        			 Purpose:
		                        			This study aimed to estimate the prevalence and predictors of portopulmonary hypertension (POPH) in children with portal hypertension. 
		                        		
		                        			Methods:
		                        			We recruited children of both sexes aged 3–15 years with portal hypertension that was clinically suspected and confirmed by the presence of varices on esophagogastroduodenoscopy (EGD). The participants underwent clinical examination, 6-min walk distance (6-MWD), and echocardiography. 
		                        		
		                        			Results:
		                        			We enrolled 94 children with portal hypertension: 26.6% with pre-hepatic causes and 73.4% secondary to chronic liver disease. Among our participants, 13.8% had one or more cardiac manifestations, such as exercise intolerance, dyspnea on exertion, cyanosis, or orthopnea, whereas 86.2% were asymptomatic. EGD examination revealed grade I varices in 54.3% of cases, grade II–III in 43.6%, and grade IV in 2.1%. Pulmonary hypertension (>35 mmHg) was detected in 30.9% of cases using echocardiography; two of them were >45 mmHg. Patients with POPH had significantly more frequent dyspnea on exertion, lower O 2 saturation, and more severe variceal grades than those with normal pulmonary artery pressure. Five (6.9%) cases had <300 m 6-MWD, with no significant difference between patients with normal and those with elevated pulmonary artery pressure. The duration of portal hypertension and 6-MWD were correlated significantly with the echocardiographic measures. High-grade varices (p=0.04) and low O 2 saturation (p=0.03) were identified as risk factors for POPH. 
		                        		
		                        			Conclusion
		                        			POPH was detected in 30.9% of our study group. High-grade varices and low O 2 saturation are predictors of POPH. Echocardiography screening is crucial for the early detection of cases. 
		                        		
		                        		
		                        		
		                        	
3.Prevalence and Predictors of Pulmonary Hypertension in Children with Portal Hypertension: A Single Center Study
Nehal El KOOFY ; Sawsan Hassan OKASHA ; Hala Mounir AGHA ; Noha ALI ; Ahmed Said BEHAIRY ; Hanan Mina FOUAD ; Rehab Hamdy ZAWAM
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):101-112
		                        		
		                        			 Purpose:
		                        			This study aimed to estimate the prevalence and predictors of portopulmonary hypertension (POPH) in children with portal hypertension. 
		                        		
		                        			Methods:
		                        			We recruited children of both sexes aged 3–15 years with portal hypertension that was clinically suspected and confirmed by the presence of varices on esophagogastroduodenoscopy (EGD). The participants underwent clinical examination, 6-min walk distance (6-MWD), and echocardiography. 
		                        		
		                        			Results:
		                        			We enrolled 94 children with portal hypertension: 26.6% with pre-hepatic causes and 73.4% secondary to chronic liver disease. Among our participants, 13.8% had one or more cardiac manifestations, such as exercise intolerance, dyspnea on exertion, cyanosis, or orthopnea, whereas 86.2% were asymptomatic. EGD examination revealed grade I varices in 54.3% of cases, grade II–III in 43.6%, and grade IV in 2.1%. Pulmonary hypertension (>35 mmHg) was detected in 30.9% of cases using echocardiography; two of them were >45 mmHg. Patients with POPH had significantly more frequent dyspnea on exertion, lower O 2 saturation, and more severe variceal grades than those with normal pulmonary artery pressure. Five (6.9%) cases had <300 m 6-MWD, with no significant difference between patients with normal and those with elevated pulmonary artery pressure. The duration of portal hypertension and 6-MWD were correlated significantly with the echocardiographic measures. High-grade varices (p=0.04) and low O 2 saturation (p=0.03) were identified as risk factors for POPH. 
		                        		
		                        			Conclusion
		                        			POPH was detected in 30.9% of our study group. High-grade varices and low O 2 saturation are predictors of POPH. Echocardiography screening is crucial for the early detection of cases. 
		                        		
		                        		
		                        		
		                        	
4.Prevalence and Predictors of Pulmonary Hypertension in Children with Portal Hypertension: A Single Center Study
Nehal El KOOFY ; Sawsan Hassan OKASHA ; Hala Mounir AGHA ; Noha ALI ; Ahmed Said BEHAIRY ; Hanan Mina FOUAD ; Rehab Hamdy ZAWAM
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):101-112
		                        		
		                        			 Purpose:
		                        			This study aimed to estimate the prevalence and predictors of portopulmonary hypertension (POPH) in children with portal hypertension. 
		                        		
		                        			Methods:
		                        			We recruited children of both sexes aged 3–15 years with portal hypertension that was clinically suspected and confirmed by the presence of varices on esophagogastroduodenoscopy (EGD). The participants underwent clinical examination, 6-min walk distance (6-MWD), and echocardiography. 
		                        		
		                        			Results:
		                        			We enrolled 94 children with portal hypertension: 26.6% with pre-hepatic causes and 73.4% secondary to chronic liver disease. Among our participants, 13.8% had one or more cardiac manifestations, such as exercise intolerance, dyspnea on exertion, cyanosis, or orthopnea, whereas 86.2% were asymptomatic. EGD examination revealed grade I varices in 54.3% of cases, grade II–III in 43.6%, and grade IV in 2.1%. Pulmonary hypertension (>35 mmHg) was detected in 30.9% of cases using echocardiography; two of them were >45 mmHg. Patients with POPH had significantly more frequent dyspnea on exertion, lower O 2 saturation, and more severe variceal grades than those with normal pulmonary artery pressure. Five (6.9%) cases had <300 m 6-MWD, with no significant difference between patients with normal and those with elevated pulmonary artery pressure. The duration of portal hypertension and 6-MWD were correlated significantly with the echocardiographic measures. High-grade varices (p=0.04) and low O 2 saturation (p=0.03) were identified as risk factors for POPH. 
		                        		
		                        			Conclusion
		                        			POPH was detected in 30.9% of our study group. High-grade varices and low O 2 saturation are predictors of POPH. Echocardiography screening is crucial for the early detection of cases. 
		                        		
		                        		
		                        		
		                        	
5.Prevalence and Predictors of Pulmonary Hypertension in Children with Portal Hypertension: A Single Center Study
Nehal El KOOFY ; Sawsan Hassan OKASHA ; Hala Mounir AGHA ; Noha ALI ; Ahmed Said BEHAIRY ; Hanan Mina FOUAD ; Rehab Hamdy ZAWAM
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):101-112
		                        		
		                        			 Purpose:
		                        			This study aimed to estimate the prevalence and predictors of portopulmonary hypertension (POPH) in children with portal hypertension. 
		                        		
		                        			Methods:
		                        			We recruited children of both sexes aged 3–15 years with portal hypertension that was clinically suspected and confirmed by the presence of varices on esophagogastroduodenoscopy (EGD). The participants underwent clinical examination, 6-min walk distance (6-MWD), and echocardiography. 
		                        		
		                        			Results:
		                        			We enrolled 94 children with portal hypertension: 26.6% with pre-hepatic causes and 73.4% secondary to chronic liver disease. Among our participants, 13.8% had one or more cardiac manifestations, such as exercise intolerance, dyspnea on exertion, cyanosis, or orthopnea, whereas 86.2% were asymptomatic. EGD examination revealed grade I varices in 54.3% of cases, grade II–III in 43.6%, and grade IV in 2.1%. Pulmonary hypertension (>35 mmHg) was detected in 30.9% of cases using echocardiography; two of them were >45 mmHg. Patients with POPH had significantly more frequent dyspnea on exertion, lower O 2 saturation, and more severe variceal grades than those with normal pulmonary artery pressure. Five (6.9%) cases had <300 m 6-MWD, with no significant difference between patients with normal and those with elevated pulmonary artery pressure. The duration of portal hypertension and 6-MWD were correlated significantly with the echocardiographic measures. High-grade varices (p=0.04) and low O 2 saturation (p=0.03) were identified as risk factors for POPH. 
		                        		
		                        			Conclusion
		                        			POPH was detected in 30.9% of our study group. High-grade varices and low O 2 saturation are predictors of POPH. Echocardiography screening is crucial for the early detection of cases. 
		                        		
		                        		
		                        		
		                        	
6.Prevalence and associated factors of Dog Bites: A cross-sectional study among Primary School Children in Madawaki District Gusau, Nigeria
Ibrahim Hassan ; Salmiah Md. Said ; Ahmad Azuhairi Ariffin ; Ahmad Zaid Fattah Azman
Malaysian Journal of Medicine and Health Sciences 2022;18(No.2):81-88
		                        		
		                        			
		                        			Introduction: Dog bite is a global public health concern because it is the main risk factor for human rabies and it 
particularly affects children. In Nigeria, most dog bites are from stray dogs and their vaccination status remains unknown. Thus, this study aimed to investigate the prevalence and associated factors of dog bite among public primary 
school children in Madawaki district Gusau, Nigeria. Methods: A cross-sectional study was conducted using an unequal stratified sampling technique among 999 children aged 11 to 13-year-old at seven public primary schools from 
September 2017 to January 2020. A self-reported history of dog bites, socio-demographic characteristics, knowledge 
on interaction with dogs, knowledge on the implication of dog bites, risk behaviours of children and dog ownership 
were collected using a validated questionnaire. Results: The prevalence of dog bites was 54.5%. The predictors of 
dog bite among the children were being a male (Adjusted Odds Ratio; AOR = 2.252; Confidence Interval; CI = 1.719, 
2.949), dog ownership by respondent’s family (AOR = 1.456; Cl = 1.089, 1.946), dog ownership by neighbours of 
the respondents (AOR = 1.752; Cl =1.334, 2.303), total score for knowledge on interaction with dogs (AOR = 0.884; 
Cl = 0.858, 0.911), and total score for risk behaviours of children (AOR = 1.020; Cl =1.004, 1.035). Conclusion: Poor 
knowledge on interaction with dogs, children’s risk behaviours around dogs, dog ownership and being male were 
the factors associated with a high prevalence of dog bite among primary school children from this study. These factors should be considered in order to develop an effective awareness campaign in schools to reduce the prevalence 
of dog bites among children.
		                        		
		                        		
		                        		
		                        	
7.Aetiologies of Liver Cirrhosis among Adult Patients Attending A Hepatology Clinic at Selangor, Malaysia
Chieng Jin Yu ; Pan Yan ; Liew Chiat Fong ; Mazawawi Muhammad ; Syed Anas Tamamulqomar Said Abu Hassan
International Journal of Public Health Research 2022;12(no.1):1493-1501
		                        		
		                        			Introduction :
		                        			Liver cirrhosis is an important cause of morbidity and mortality.
		                        		
		                        			Methods:
		                        			Our study aimed to describe the clinical pattern of cirrhosis and its associated factors among adult patients attending Hepatology Clinic, Serdang Hospital, Malaysia from 1st January 2010 to 30th June 2017. Aetiology was further determined by history, biochemistry and/or histology. The severity of the cirrhosis, together with the presence of complications and incidence of hepatocellular carcinoma were documented.
		                        		
		                        			Results:
		                        			A total of 357 adult patients were diagnosed with cirrhosis including 199 male patients (55.7%) and 158 female patients (44.3%), with a mean age of 54-year-old (range: 28-84 year-old). The causes of cirrhosis were chronic hepatitis B (N=145, 40.6%), chronic hepatitis C (N= 67, 18.8%), cryptogenic liver disorder (N= 63, 17.6%), alcohol (N=42, 11.8%), non-alcoholic fatty liver disease (N=25, 7.0%), and others (N=15, 4.2%). Chronic hepatitis B was the predominant aetiology among Chinese whereas alcohol was the main aetiology among Indians, and Hepatitis C cirrhosis was highest among Malays. Majority of the patients had compensated cirrhosis with Child-Pugh A (N=221, 61.9%) at the time of diagnosis. 80.4% (N=287) of the cirrhotic patients had performed at least one endoscopy surveillance, with 28.6% (82/287) of them had endoscopic evidence of portal hypertension. 32.2% of patients had at least one hospitalization due to complication of cirrhosis. 41 patients (11.5%) had concurrent hepatocellular carcinoma during the follow up.
		                        		
		                        			Conclusions
		                        			Despite universal hepatitis B vaccination, Hepatitis B viral infection remains the most common cause of cirrhosis among patients attending Hepatology Clinic, Serdang Hospital.
		                        		
		                        		
		                        		
		                        	
8.Recycling Potential of Natural Waste Products in the Development of Fingerprint Powders for Forensic Application
Nur Fatin Nabihah Said ; Siti Nabilah Anuar ; Yusmazura Zakaria ; Revathi Rajan ; Nurasmat Mohd Shukri ; Nik Fakhuruddin Nik Hassan
Malaysian Journal of Medicine and Health Sciences 2021;17(No.4):196-204
		                        		
		                        			
		                        			Introduction: The most common method to emerge latent fingermarks on non-porous surfaces is powdering by 
applying commercial fingerprint powders. However, the chemical composition of the powder is often toxic and 
poses health hazards to humans. This study was endeavoured to explore the effectiveness and potential use of natural resources for the enhancement of latent fingermarks. Methods: Eggshells and clamshells were prepared in fine 
powder form, and latent fingermarks were developed using each powder. Five non-porous substrates were selected 
for fingermarks deposition; glass, aluminium can, plastic book cover, painted wood, and compact disc. Results: Both 
natural powders have successfully developed high-quality finger marks with high clarity of ridge characteristics in 
comparison to commercial fingerprint powder (positive control) and untreated fingermark (negative control) on most 
of the tested surfaces tested. The sebaceous fingermarks have shown the best quality fingermarks when developed 
with both powders. In the ageing study, it was found that most non-porous substrates bearing latent fingermarks 
exposed to the destructive conditions can be successfully visualised in the early period of exposure. Conclusion: 
Eggshell and clamshell powders are as effective as commercial white powder but preferrable to be applied because 
of the low cost, abundant and non-hazardous. 
		                        		
		                        		
		                        		
		                        	
9.Health Education on The Knowledge of First Aid in Traffic Accidents in Students at Tunas Husada High School Kendari, Indonesia
Islaeli Islaeli ; Anisa Purnamasari ; Ari Nofitasari ; Faridah Mohd Said ; Hafizah Che Hassan
Malaysian Journal of Medicine and Health Sciences 2020;16(Supp 10, November):38-42
		                        		
		                        			
		                        			Introduction:  Accidents including traffic accidents can occur anywhere, anytime. Around the world, 1.2 million die each year from accidents, and 50 million are injured. Indonesia has the fifth highest rate of accidents. The consequences of unexpected accidents can be life threatening, on an average one traffic accident occurs every 0.5 minutes. Cardiac Pulmonary Resuscitation (CPR) is an individual's skill to save a person's life. This is very important in the first five minutes in a victim's life in many emergency situations. In an emergency, bystander including children in the high school is expected to perform a core role in carrying out CPR. The aim of this study is to determine CPR knowledge in High School. Methods: The type of research is a pre-experimental research by approaching the One Group Pre and Post Test Design. Intervention study using pre and post-test validated questionnaire was conducted among 40 students of Tunas Husada high school that were randomly selected.  Data analysis was performed with the Macnemar test. Results: The results of the study obtained p= 0.000 which is less than 0.05, so result of the study reveal significant difference in knowledge before and after health education. Thus, there is an effect of health education in increasing knowledge of first aid in traffic accidents among students at Tunas Husada high school, Kendari. Conclusion: This study identify that majority students has poor knowledge on CPR. Therefore, implementation of basic life-support training for all school children is recommenced.
		                        		
		                        		
		                        		
		                        	
10.The effectiveness of theory-based intervention to improve haemoglobin levels among women with anaemia in pregnancy
Hasneezah Hassan ; Rosliza Abdul Manaf ; Salmiah Md Said ; Geeta Appannah
The Medical Journal of Malaysia 2020;75(6):626-634
		                        		
		                        			
		                        			health problem throughout the world. The effects of theexisting   intervention   in   ensuring   compliance   to   thesubscribed regimen and the impact of nutrition education inenhancing   dietary   modification   during   pregnancy   inMalaysia have been minimal. This study aims to develop,implement and evaluate the effects of the Health BeliefModel educational intervention on haemoglobin level amonganaemic pregnant women.Methods: This is a quasi-experimental research with pre-post test design with control group involving 81 participantsper group from two health clinics in Sepang. The primaryoutcome was a change in the haemoglobin levels followingeducational intervention. Secondary outcomes includeknowledge   on   anaemia,   Health   Belief   Model   (HBM)constructs, dietary iron intake and compliance towards ironsupplementation. The intervention group received a HBM-based education intervention programme. Results: The response rate in the intervention and controlgroup were 83.9% and 82.7% respectively. Generalisedestimating equations analysis showed that the interventionwas effective in improving the mean haemoglobin level(β=0.75, 95%CI=0.52, 0.99, p<0.001), the knowledge score(β=1.42, 95%CI=0.36, 2.49, p=0.009), perceived severityscore (β=2.2, 95%CI= 1.02, 3.39, p<0.001) and increasedproportion of high compliance level (AOR=4.59, 95%CI=1.58,13.35, p=0.005).Conclusion: HBM-based health education programme hasproven to be effective in improving the haemoglobin levels,knowledge   scores,   perceived   severity   scores   andcompliance   level   of   participants.   The   study   resultsemphasized on the effectiveness of such an approach,therefore   it   is   recommended   that   future   educationalinterventions which aim at increasing preventive healthybehaviours in pregnant women may benefit from theapplication of this model in primary health care settings. 
		                        		
		                        		
		                        		
		                        	
            

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