1.Gait Instability and Compensatory Mechanisms in Parkinson’s Disease Patients With Camptocormia: An Exploratory Study
Hideyuki URAKAMI ; Yasutaka NIKAIDO ; Yuta OKUDA ; Yutaka KIKUCHI ; Ryuichi SAURA ; Yohei OKADA
Journal of Movement Disorders 2025;18(2):127-137
Objective:
Camptocormia contributes to vertical gait instability and, at times, may also lead to forward instability in experimental settings in Parkinson’s disease (PD) patients. However, these aspects, along with compensatory mechanisms, remain largely unexplored. This study comprehensively investigated gait instability and compensatory strategies in PD patients with camptocormia (PD+CC).
Methods:
Ten PD+CC patients, 30 without camptocormia (PD-CC), and 27 healthy controls (HCs) participated. Self-paced gait tasks were analyzed using three-dimensional motion capture systems to assess gait stability as well as spatiotemporal and kinematic parameters. Unique cases with pronounced forward gait stability or instability were first identified, followed by group comparisons. Correlation analysis was performed to examine associations between trunk flexion angles (lower/upper) and gait parameters. The significance level was set at 0.05.
Results:
Excluding one unique case, the PD+CC group presented a significantly lower vertical center of mass (COM) position (p=0.019) increased mediolateral COM velocity (p=0.004) and step width (p=0.013), compared to the PD-CC group. Both PD groups presented greater anterior‒posterior margins of stability than did the HCs (p<0.001). Significant correlations were found between lower/upper trunk flexion angles and a lower vertical COM position (r=-0.690/-0.332), as well as increased mediolateral COM velocity (r=0.374/0.446) and step width (r=0.580/0.474).
Conclusion
Most PD+CC patients presented vertical gait instability, increased fall risk, and adopted compensatory strategies involving greater lateral COM shift and a wider base of support, with these trends intensifying as trunk flexion angles increased. These findings may guide targeted interventions for gait instability in PD+CC patients.
2.Gait Instability and Compensatory Mechanisms in Parkinson’s Disease Patients With Camptocormia: An Exploratory Study
Hideyuki URAKAMI ; Yasutaka NIKAIDO ; Yuta OKUDA ; Yutaka KIKUCHI ; Ryuichi SAURA ; Yohei OKADA
Journal of Movement Disorders 2025;18(2):127-137
Objective:
Camptocormia contributes to vertical gait instability and, at times, may also lead to forward instability in experimental settings in Parkinson’s disease (PD) patients. However, these aspects, along with compensatory mechanisms, remain largely unexplored. This study comprehensively investigated gait instability and compensatory strategies in PD patients with camptocormia (PD+CC).
Methods:
Ten PD+CC patients, 30 without camptocormia (PD-CC), and 27 healthy controls (HCs) participated. Self-paced gait tasks were analyzed using three-dimensional motion capture systems to assess gait stability as well as spatiotemporal and kinematic parameters. Unique cases with pronounced forward gait stability or instability were first identified, followed by group comparisons. Correlation analysis was performed to examine associations between trunk flexion angles (lower/upper) and gait parameters. The significance level was set at 0.05.
Results:
Excluding one unique case, the PD+CC group presented a significantly lower vertical center of mass (COM) position (p=0.019) increased mediolateral COM velocity (p=0.004) and step width (p=0.013), compared to the PD-CC group. Both PD groups presented greater anterior‒posterior margins of stability than did the HCs (p<0.001). Significant correlations were found between lower/upper trunk flexion angles and a lower vertical COM position (r=-0.690/-0.332), as well as increased mediolateral COM velocity (r=0.374/0.446) and step width (r=0.580/0.474).
Conclusion
Most PD+CC patients presented vertical gait instability, increased fall risk, and adopted compensatory strategies involving greater lateral COM shift and a wider base of support, with these trends intensifying as trunk flexion angles increased. These findings may guide targeted interventions for gait instability in PD+CC patients.
3.Gait Instability and Compensatory Mechanisms in Parkinson’s Disease Patients With Camptocormia: An Exploratory Study
Hideyuki URAKAMI ; Yasutaka NIKAIDO ; Yuta OKUDA ; Yutaka KIKUCHI ; Ryuichi SAURA ; Yohei OKADA
Journal of Movement Disorders 2025;18(2):127-137
Objective:
Camptocormia contributes to vertical gait instability and, at times, may also lead to forward instability in experimental settings in Parkinson’s disease (PD) patients. However, these aspects, along with compensatory mechanisms, remain largely unexplored. This study comprehensively investigated gait instability and compensatory strategies in PD patients with camptocormia (PD+CC).
Methods:
Ten PD+CC patients, 30 without camptocormia (PD-CC), and 27 healthy controls (HCs) participated. Self-paced gait tasks were analyzed using three-dimensional motion capture systems to assess gait stability as well as spatiotemporal and kinematic parameters. Unique cases with pronounced forward gait stability or instability were first identified, followed by group comparisons. Correlation analysis was performed to examine associations between trunk flexion angles (lower/upper) and gait parameters. The significance level was set at 0.05.
Results:
Excluding one unique case, the PD+CC group presented a significantly lower vertical center of mass (COM) position (p=0.019) increased mediolateral COM velocity (p=0.004) and step width (p=0.013), compared to the PD-CC group. Both PD groups presented greater anterior‒posterior margins of stability than did the HCs (p<0.001). Significant correlations were found between lower/upper trunk flexion angles and a lower vertical COM position (r=-0.690/-0.332), as well as increased mediolateral COM velocity (r=0.374/0.446) and step width (r=0.580/0.474).
Conclusion
Most PD+CC patients presented vertical gait instability, increased fall risk, and adopted compensatory strategies involving greater lateral COM shift and a wider base of support, with these trends intensifying as trunk flexion angles increased. These findings may guide targeted interventions for gait instability in PD+CC patients.
4.Efficacy of a Novel Recording Method in Facilitating Rapid Documentation of Disaster Rehabilitation Support Activities
Akira MORIKAWA ; Masao TOMIOKA ; Ryuichi SAURA
The Japanese Journal of Rehabilitation Medicine 2024;():23050-
Objective:An efficient disaster relief service necessitates the documentation and dissemination of information acquired from disaster response-related activities. However, recording and summarizing information pertaining to rehabilitation support activities is time-consuming and a pressing concern;therefore, mark-sheet forms have been introduced to reduce the time required for this process. Therefore, this study aimed to examine whether mark-sheet forms can facilitate a more accurate and rapid recording of information than conventional descriptive recording forms.Methods:Fifty physical therapists affiliated with the Osaka Physical Therapists Association with no history of performing disaster rehabilitation support activities were recruited. Participants were randomized into descriptive recording form and mark-sheet form groups. Individuals in both groups were instructed to document the information gathered by watching simulated videos of the rehabilitation support activities on their designated recording forms. A statistical analysis compared the accuracy and time required to record the data obtained from the 10 simulation videos between groups.Results:In all 10 scenarios, the recording time was significantly shorter (p<0.05) for the mark-sheet form than descriptive recording form group. However, no discernible intergroup difference was observed in recorded content accuracy.Conclusion:The use of mark-sheet versus descriptive recording forms facilitated more rapid documentation of disaster rehabilitation support activities.
5.Experience of Rehabilitation Treatment for Osmotic Demyelination Syndrome with Locked-in Syndrome
Akane DOI ; Masao TOMIOKA ; Ryuichi SAURA ; Fumiharu KIMURA ; Shin OTA ; Takafumi HOSOKAWA
The Japanese Journal of Rehabilitation Medicine 2024;():23015-
Osmotic demyelination syndrome is a pathological condition that leads to electrolyte imbalances and rapid correction, resulting in pseudobulbar palsy, quadriplegia, and altered consciousness. Approximately 33-55% of affected patients experience residual functional impairment. Herein, we describe a case of a patient with osmotic demyelination syndrome who developed locked-in syndrome during the disease course, underwent rehabilitation treatment, and achieved complete remission without sequelae.The patient was a 47-year-old man who was admitted to hospital A owing to weakness in the lower extremities and dysarthria. He had severe hyponatremia and received sodium correction. However, on hospital day 9, dysarthria redeveloped and involuntary finger movements were noted. Osmotic demyelination syndrome was suspected based on the findings of magnetic resonance imaging of the head and clinical course, leading to his transfer to hospital B. Steroid pulse and rehabilitation therapies were initiated at hospital B. By the 19th day of symptom onset, his limb and facial muscle paralysis progressed, leading to locked-in syndrome. Thereafter, the patient was transferred to hospital C, where he received physiotherapy, occupational therapy, and eating training, markedly improving his physical functions. He was discharged from hospital C, 4 months after the symptom onset, with limited range of motion of the fingers and weakness of the extremities and continued to receive outpatient rehabilitation treatment. His symptoms improved further, and 1 year after the onset of symptoms, he returned to work without any sequelae.
6.Experience of Rehabilitation Treatment for Osmotic Demyelination Syndrome with Locked-in Syndrome
Akane DOI ; Masao TOMIOKA ; Ryuichi SAURA ; Fumiharu KIMURA ; Shin OTA ; Takafumi HOSOKAWA
The Japanese Journal of Rehabilitation Medicine 2024;61(3):209-215
Osmotic demyelination syndrome is a pathological condition that leads to electrolyte imbalances and rapid correction, resulting in pseudobulbar palsy, quadriplegia, and altered consciousness. Approximately 33-55% of affected patients experience residual functional impairment. Herein, we describe a case of a patient with osmotic demyelination syndrome who developed locked-in syndrome during the disease course, underwent rehabilitation treatment, and achieved complete remission without sequelae.The patient was a 47-year-old man who was admitted to hospital A owing to weakness in the lower extremities and dysarthria. He had severe hyponatremia and received sodium correction. However, on hospital day 9, dysarthria redeveloped and involuntary finger movements were noted. Osmotic demyelination syndrome was suspected based on the findings of magnetic resonance imaging of the head and clinical course, leading to his transfer to hospital B. Steroid pulse and rehabilitation therapies were initiated at hospital B. By the 19th day of symptom onset, his limb and facial muscle paralysis progressed, leading to locked-in syndrome. Thereafter, the patient was transferred to hospital C, where he received physiotherapy, occupational therapy, and eating training, markedly improving his physical functions. He was discharged from hospital C, 4 months after the symptom onset, with limited range of motion of the fingers and weakness of the extremities and continued to receive outpatient rehabilitation treatment. His symptoms improved further, and 1 year after the onset of symptoms, he returned to work without any sequelae.
7.Efficacy of a Novel Recording Method in Facilitating Rapid Documentation of Disaster Rehabilitation Support Activities
Akira MORIKAWA ; Masao TOMIOKA ; Ryuichi SAURA
The Japanese Journal of Rehabilitation Medicine 2024;61(8):757-766
Objective:An efficient disaster relief service necessitates the documentation and dissemination of information acquired from disaster response-related activities. However, recording and summarizing information pertaining to rehabilitation support activities is time-consuming and a pressing concern;therefore, mark-sheet forms have been introduced to reduce the time required for this process. Therefore, this study aimed to examine whether mark-sheet forms can facilitate a more accurate and rapid recording of information than conventional descriptive recording forms.Methods:Fifty physical therapists affiliated with the Osaka Physical Therapists Association with no history of performing disaster rehabilitation support activities were recruited. Participants were randomized into descriptive recording form and mark-sheet form groups. Individuals in both groups were instructed to document the information gathered by watching simulated videos of the rehabilitation support activities on their designated recording forms. A statistical analysis compared the accuracy and time required to record the data obtained from the 10 simulation videos between groups.Results:In all 10 scenarios, the recording time was significantly shorter (p<0.05) for the mark-sheet form than descriptive recording form group. However, no discernible intergroup difference was observed in recorded content accuracy.Conclusion:The use of mark-sheet versus descriptive recording forms facilitated more rapid documentation of disaster rehabilitation support activities.
8.A Case of Response to Keishikajutsubuto for Stump Pain after Both Femoral Amputation
Yoshito HAMANAMI ; Junsuke ARIMITSU ; Keiko OGAWA-OCHIAI ; Yoshinobu MATSUMORI ; Ryuichi SAURA
Kampo Medicine 2023;74(4):348-352
We have experienced a case of response to keishikajutsubuto for stump pain after both femoral amputations. There are few reports on the use of Kampo medicines for stump pain after amputation. In this case, the critical lower-limb ischemia that led to the amputation was due to severe stenosis and occlusion caused by arteriosclerosis in both limbs. From the perspective of Kampo medicine, ischemia is considered to have cold and blood status as a result of deficiency and stagnation of yang qi due to circulatory failure. In this case, we regarded blood stasis as a secondary product of ischemia, and we mainly considered a prescription to remove cold and bring yang qi to the eliminative organs, which was effective for the pain. For stump pain after amputation that is poorly responded to general analgesics, the combination of keishikajutsubuto is expected to provide rapid analgesic effect, suggesting that it is useful for pain control.


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