1.Baicalin induces ferroptosis in bladder cancer cells by downregulating FTH1.
Na KONG ; Xiaying CHEN ; Jiao FENG ; Ting DUAN ; Shuiping LIU ; Xueni SUN ; Peng CHEN ; Ting PAN ; Lili YAN ; Ting JIN ; Yu XIANG ; Quan GAO ; Chengyong WEN ; Weirui MA ; Wencheng LIU ; Mingming ZHANG ; Zuyi YANG ; Wengang WANG ; Ruonan ZHANG ; Bi CHEN ; Tian XIE ; Xinbing SUI ; Wei TAO
Acta Pharmaceutica Sinica B 2021;11(12):4045-4054
Ferroptosis is a non-apoptotic regulated cell death caused by iron accumulation and subsequent lipid peroxidation. Currently, the therapeutic role of ferroptosis on cancer is gaining increasing interest. Baicalin an active component in
2.Novel 16-slice mobile CT head scan in 391 patients
Zhiqiang ZHANG ; Qiusheng DAI ; Fei LI ; Fei GAO ; Yaxin JING ; Ruonan BI ; Zhenfang WANG ; Rongrong CHEN ; Lida XU ; Daiqiang YIN ; Zhonghua YU ; Qiang ZHANG ; Ruxiang XU
Chinese Journal of Neuromedicine 2018;17(2):184-188
Objective To discuss the application of self-developed novel 16-slice mobile CT head scan.Methods A total of 391 patients were performed 16-slice mobile CT scan:145 were scanned in the emergency department,156 in the neurosurgical ICU,55 in the operated room,and 35 in the ambulance vehicle.Sixty-eight patients were with brain injury,122 were with cerebral hemorrhage,120 were with cerebral infarction,59 were with brain tumors,and 22 were with hemifacial spasm.Thirty-five patients were randomly selected from 391 patients and 8-slice mobile CT head scan was performed on them,which included 12 with brain injury,6 with cerebral hemorrhage,12 with cerebral infarction,3 with brain tumors and 2 with hemifacial spasm.The resolution,imaging quality,radiation doses,power consumption and performance stability of novel 16-slice mobile CT and 8-slice mobile CT head scan were compared.Results The resolution line pairs of brain tissues were 91 p/cm by 16-slice mobile CT and 71 p/cm by 8-slice mobile CT,respectively.The imaging quality of the two kinds of mobile CT head scans was high level to the clinic diagnostic criteria.The radiation dose of 16-slice mobile CT were 40.43 mGy,which decreased by 51.01% as compared with that of 8-slice mobile CT (82.52 mGy).The personal power consumption of 16-silce mobile CT (0.29 kW· h) decreased by 38.30% as compared with those of 8-layer mobile CT (0.47 kW· h).The 16-slice mobile CT kept regularly,while 8-slicer mobile CT stopped to work twice during clinical trial.Conclusion The 16-slice mobile CT scan has high resolution,fine imaging quality,low radiation dose,small power consumption and stable working performance.

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