Objective:To explore status of nutritional knowledge, attitude and practice of tumor nursing staff and analyze the influencing factors.Methods:Using the convenient sampling method, a total of 800 nurses from Cancer Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College were selected as the research objects from January to February 2021. General data questionnaire, Nutrition Knowledge, Attitude and Practice Questionnaire for Tumor Nursing Staff and Nutrition Knowledge Acquisition Way Questionnaire for Tumor Nursing Staff were used to investigate. A total of 800 questionnaires were sent out and 797 were valid.Results:For 797 tumor nursing staff, the total score of Nutrition Knowledge, Attitude and Practice Questionnaire for Tumor Nursing Staff was (63.50±14.87) . The passing rate was 62.0% and the excellent rate was 13.8%. The results of multivariate analysis showed that professional title, educational background and department were the influencing factors of nutrition knowledge, attitude and practice of tumor nurses ( P<0.05) . Conclusions:Tumor nursing staff have positive attitudes and practice towards nutrition therapy, but their knowledge of nutrition needs to be strengthened. It is necessary to carry out nutrition-related training based on influencing factors.

Objective:To explore the dissipation of hyperthermic intraperitoneal chemotherapy (HIPEC) drugs configured in the biological safety cabinet in the Operating Room.Methods:From February 2018 to October 2019, convenience sampling was used to select 60 patients with gastrointestinal malignancies who received HIPEC in the Operating Room of the Cancer Hospital of the Chinese Academy of Medical Sciences as the research object. Patients were divided into four groups according to the order of operation time, with 15 cases in each group. In the control group, there was no protection on the HIPEC configuration table for patients with gastrointestinal malignancies. In the isolation pad group, the HIPEC configuration table for patients with gastrointestinal malignancies was flat with an isolation pad of the same area as the table. In the medical gauze group, the HIPEC configuration table for patients with gastrointestinal malignancies was covered with medical gauze of the same area as the table. In the medical absorbent paper group, the HIPEC configuration table for patients with gastrointestinal malignancies was laid flat with medical absorbent paper of the same area as the table. The four groups all adopted conventional protection methods for the configuration staff, that was, the configuration staff routinely wore special clothing and hats of the Operating Room, wore disposable masks and latex gloves. The positive rate of chemotherapy drugs and the residual cisplatin concentration of each group of countertop samples, glove samples, auricle wipe samples and mask samples were compared.Results:There was a statistically significant difference in the positive rate of drug residues in countertop samples from different groups ( P<0.01) .Among them, the positive rates of countertop samples in the isolation pad group, medical absorbent paper group, and medical gauze group were lower than that of the control group, and the difference was statistically significant ( P<0.01) . There was no statistically significant difference in the positive rate of drug residues in glove samples, auricle wipe samples and mask samples in different groups ( P>0.05) .The difference of drug residue concentration in countertop samples of different groups was statistically significant ( P<0.01) . Among them, the concentration of drug residue in countertop samples of the isolation pad group, medical absorbent paper group, and medical gauze group was lower than that of the control group, and the difference was statistically significant ( P<0.01) .There was no significant difference in drug residue concentration in glove samples, auricle wipe samples and mask samples in different groups ( P>0.05) . Conclusions:Covering the table with isolation pads, medical gauze and medical absorbent paper can effectively reduce the residual concentration of chemotherapy drugs on the biosafety countertop.

BACKGROUND: The clinical trials of new anti-tumor drugs are prospering in China. The acceptance of clinical trials in patients is an important factor affecting the speed and quality of clinical trials. Previous studies have investigated the acceptance of clinical trials in those cancer patients, who have never participated in a trial. This study is designed to investigate and compare the acceptance and related causes of clinical trials in cancer patients who have once participated in a clinical trial or not. METHODS: From June 2018 to April 2019, a standardized questionnaire-based survey was conducted among two groups of cancer patients classified by history of clinical trial participation in Cancer hospital, Chinese Academy of Medical Science, mainly focusing on their overall acceptance of clinical trials and related considerations, including the role of attending doctors, as well as group differences between the two participants. RESULTS: A total of 538 patients were enrolled with an average age of 53.5 years old, 51.1% of whom were males, and 43.3% of whom have never participated in a clinical trial. Overall, 502 patients (93.3%) were willing to or recommend their relatives or friends to participate in clinical trials, and patients with history of clinical trial participation had higher willingness (96.6% vs 90.8%, P=0.008). Patients were most likely to be motivated by expectation of optimal treatment (100.0% vs 99.3%) for both those who had once participated in a clinical trial or those not, respectively followed by financial burden reduction (56.0%) and recommendation by attending doctor (43.7%). The main reasons for unwillingness-to-participate for those who had once participated in a clinical trial were abandoning other treatment options, divided into control group or additional visits, while for those who had never participated in a clinical trial, ineffective treatment or serious adverse reactions were their main concerns. In the decision-making of clinical trial participation, 88% patients highly valued the role of recommendation by attending doctors. Among patients without trial participation history, 60.9% of those had no unwillingness-to-participate expressed that recommendation by attending doctors would change their decisions. The study also reported patients' preferences for information and access to clinical trials. CONCLUSIONS The acceptance of clinical trials in cancer patients in our hospital is generally high, especially in patients who had a history of trial participation. It's of substantial significance to give full play to the role of doctors in improving the acceptance of clinical trials of cancer patients in China.

BACKGROUND: Early investigation suggested patients' level of awareness regarding clinical trials was related with willingness to participation. This study was intended to evaluate the level of awareness of cancer patients regarding clinical trials and related influencing factors, and to compare the differences of awareness between patients who attended clinical trials before and not. METHODS: From Jun, 2018 to April, 2019, standardized question-naires were gathered from cancer patients (attended clinical trials vs not attended clinical trials) in our hospital regarding basic information and 10 other questions about awareness. The level of awareness was evaluated and patients were classified into "low cognition" and "high cognition" groups. Logistic regression analysis was performed to determine whether certain characteristics would predict for awareness. RESULTS: Of the 617 participants, 38.6% have attended clinical trials before. 338 (54.6%) patients had a correct overall understanding of clinical trials, while 44 (7.1%) patients still thought participants were the victim of scientific research. Except for the compensation of medical expenses (51.5% vs 48.7%) and related laws of clinical trials (52.3% vs 45.5%), other parts of understanding were elevated in patients attended clinical trials before comparing with patients who didn't, including significance (86.2% vs 77.6%), risk disclosure (91.2% vs 71.6%), confidentiality (73.2% vs 59.7%), voluntariness (95.8% vs 76.3%), withdrawal (86.6% vs 68.2%) and expenses (62.8% vs 39.2%). The proportion of participants who understand these components did not increase even in 239 patients who had attended clinical trials before. Participants who attended clinical trials before (OR=1.83, 95%CI: 1.11-3.00), unmarried/divorced (OR=5.04, 95%CI: 1.73-14.66), retired (OR=2.53, 95%CI: 1.16-5.50) had a higher level of awareness, while patients who had bad impression with doctors (OR=0.43, 95%CI: 0.26-0.72) had lower awareness. CONCLUSIONS The current level of awareness for clinical trials of cancer patients in our hospital was relatively low, even in patients who had attended clinical trials before. It's necessary to improve patients' awareness of clinical trial by promoting harmony relationship between patients and doctors, as well as by enhancing related propagation. Strengthening the adequacy and efficacy of informed consent in clinical trials also needs to be achieved in the future.

Objective:To explore the current status of discharge readiness and social support in patients of colorectal neoplasms after natural orifice specimen extraction surgery (NOSES) , and to analyze the correlation between them.Methods:The convenient sampling method was used to select 200 patients with colorectal neoplasms after NOSES in Department of Colorectal Surgery of a ClassⅢ Grade A tumor hospital in Beijing from January 2018 to October 2019 as the research objects. They were investigated by General information questionnaire, Readiness for Hospital Discharge Scale (RHDS) and Social Support Rating Scale (SSRS) .Results:The total scores of RHDS and SSRS of 200 patients with colorectal neoplasms were respectively (154.69±33.66) and (42.09±8.74) . The total score of RHDS was positively correlated with the total score of SSRS ( P<0.01) . Conclusions:Discharge readiness and social support of patients of colorectal neoplasms after NOSES are at a moderate level. Medical staff should make full use of the social support system to help patients adopt active coping methods and improve their discharge readiness.

Objective:To observe the adverse effects of skin toxicity after the administration of programmed cell death protein 1 (PD-1) inhibitor, summarize the nursing measures, and provide a basis for taking corresponding management measures.Methods:Totally 94 patients who were treated with PD-1 inhibitor in Cancer Hospital of Chinese Academy of Medical Sciences between February and October 2019 were selected by convenient sampling, among whom 37 cases (39.4%) with skin toxicity reaction were included as the research subjects. Their skin toxicity was observed and assessed. Meanwhile, health education, psychological counseling and nursing care for skin toxicity reaction were provided to them.Results:Of the 37 patients, 34 (91.9%) had G1 skin toxicity and were not treated with drugs. After the rash subsided, they were treated according to the original plan. 2 (5.4%) had G2 skin toxicity, whose rash subsided after drug treatment, with scattered pigmentation. They were treated according to the original plan. 1 (2.7%) had G4 skin toxicity. The medical staff from the Dermatology Department and the Infection Department were consulted. The body temperature was normal, and the skin and mucous membranes were ruptured, crusted and detached. The patient was discharged after the condition was improved.Conclusions:After receiving PD-1 inhibitor immunotherapy, patients may have different degrees of immune-related skin toxicity reactions, which requires clinicians and nurses to carry out standardized treatment and care to improve their quality of life.

Objective To learn the intention and demand of nurses of cancer hospitals to train abroad, so as to promote international exchange and management of nursing work. Methods Investigation was carried out by self-designed questionnaires among the nurses at the cancer hospital.The questionnaire covered the basic information of the nurses, the intention and demand of studying abroad, and information of those who have completed study abroad. The differences among different age groups were compared by descriptive statistics and χ2 test. Results Of the 700 people surveyed, 71.7% (502/700) of the nurses expect to study and train abroad.Their main purpose was to learn new nursing skills, new knowledge and nursing supervision methods.Nurses expect to study and train abroad for updating their concepts, promoting nursing skills, improving their command of a foreign language, and enhancing knowledge update ability. 54.9% (384/700)of the respondents were found with concerns for studying abroad.67.4% (33/49) of the respondents had the assessments after returning home. And 69.4% (34/49) of the respondents had more opportunities after their return. Conclusions It is important for nurses to study and train abroad.To this end, a gradient and hierarchical platform should be developed for nurses to go abroad for study under an institutionalized framework. It is also necessary to build an international communication platform and to establish a long-term evaluation and assessment mechanism.

This paper reported the responsibility of nurses in symptom management among cancer patients. Besides, we also reviewed the current situation of cancer symptom management at home and abroad and prospected the trend of symptom nursing management of cancer patients, so as to put forward a suggestion on how nurses played a role in symptom management.

Objective? To compare predicted incidence of chemotherapy induced nausea and vomiting (CINV) by doctors, nurses and patients with its actual incidence. Methods? We used the prospective paired design to select 320 patients with the induced vomiting plan of medicine department at Peking Union Medical College Cancer Hospital by convenience sampling, and we allocated 72 doctors and 48 responsibility nurses for patients. The predicted chemotherapy induced nausea and vomiting scale was filled in by doctors, nurses and patients as required to understand the incidence of CINV predicted by them. After patients completed their chemotherapy, the Chinese version of MASCC antiemesis tool (MAT) was filled out by nurses to investigate the actual incidence of CINV. Results? The paired chi-square test showed that the incidence of acute and delayed CINV were 38.75% and 61.25% respectively. There was no statistical difference between the incidence of acute CINV predicted by doctors, nurses as well as patients and the actual incidence (P＞0.05). There was also no statistical difference between the incidence of delayed CINV predicted by nurses and the actual incidence (P＞0.05). Doctors and patients all underestimated the incidence of delayed CINV with a statistical difference (P＜0.05). The consistency between the incidence of acute as well as delayed CINV predicted by doctors, nurses, patients and the actual incidence was poor with Kappa value ranging from 0.02 to 0.34. A total of 54.93% to 57.77% of doctors and nurses predicted that CINV could be controlled well lower than that (about 70%) of patients with statistical differences (P＜0.05). Conclusions? There is still much improvement space for control of delayed CINV. Medical staff should take effective measures to improve the level of estimate and the level of CINV symptom management, and to improve the quality of life among patients.

Objective? To compare the evaluation result of 10 symptoms including poor appetite in cancer patients during chemotherapy from the patients and their nurses, in order to improve the assessment and judgment ability of the responsible nurses on the symptoms of patients undergoing chemotherapy through the analysis of the result. Methods? The study was performed in the chemotherapy unit of a cancer ClassⅢGrade A hospital in Beijing. By convenience sampling, a total of 192 patients undergoing chemotherapy from October 2017 to January 2018 and the nurses (n=16) who were primarily responsible for their care were selected as participants. Symptom assessments were completed by the use of the Edmonton Symptom Assessment System (ESAS). Results? Patients and nurses showed poor agreement in Depression, Anxiety and Shortness of breath (ICC＜ 0.4) and moderate agreement (0.4 ≤ICC＜ 0.75) in other symptoms. Wilcoxon signed rank test was used to compare the results of symptom assessment between patients and responsible nurses. Among the 10 entries in ESAS, there was no statistical difference between the results in poor quality of life (Z=-1.627, P=0.104), however, there were statistical differences in all the rest 9 entries (P＜0.05) among which the nurses scored higher than the patients in the entry of anxiety and depression. Conclusions? Responsible nurses' perception on physical symptoms was better than that of psychological symptoms, and there was overestimation and underestimation in the severity of symptoms. It is necessary for the nurses to teach the patients how to use standard assessment tools and through health education, raise the patients' awareness of reporting their symptoms.