1.Advances on selective posterior rhizotomy for lower limb function in patients with cerebral palsy.
Jie XU ; Lin XU ; Jie ZENG ; Chuan-Yu HU ; Jing-Pei REN ; Yi ZHAO ; Le WANG ; Ya-Lin ZHAO ; Xiao-Hong MU
China Journal of Orthopaedics and Traumatology 2020;33(5):489-492
		                        		
		                        			
		                        			Cerebral palsy is a common clinical syndrome of neurological disability in childhood, which seriously affects the quality of life of children and their families, and brings a heavy economic burden to the society. Domestic and foreign scholars had a long history of the application of selective posterior rhizotomy for the treatment of spastic cerebral palsy or mixed cerebral palsy with limb paralysis. It is effective in improving the lower extremity spasm of patients with cerebral palsy, and there are few cases with recurrences. After rehabilitation therapy, the muscle strength of patients with cerebral palsy was significantly improved compared with the previous one. The range of motion was significantly improved after operation, and there is no rebounded in aspect of joint activety in the long-term follow-up. The overall gait of the patient was significant improved. The author thought that selective posterior rhizotomy is effective in improving the motor function of lower limbs in patients with cerebral palsy, and it is worth being spread. However, it has to follow the principle of selecting appropriate cases before surgery, precise operation during operation, and timely and effective rehabilitation treatment after surgery, in order to achieve a better curative effect.
		                        		
		                        		
		                        		
		                        			Cerebral Palsy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lower Extremity
		                        			;
		                        		
		                        			Muscle Spasticity
		                        			;
		                        		
		                        			Quality of Life
		                        			;
		                        		
		                        			Rhizotomy
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
2.Gamma Knife Radiosurgery in Recurrent Trigeminal Neuralgia after Other Procedures
Jae Meen LEE ; Beong Ik HUR ; Chang Hwa CHOI
Kosin Medical Journal 2019;34(1):30-37
		                        		
		                        			
		                        			OBJECTIVES: Trigeminal neuralgia (TN) is undurable paroxysmal pain in the distribution of the fifth cranial nerve. Invasive treatment modalities for TN include microvascular decompression (MVD) and percutaneous procedures, such as, radiofrequency rhizotomy (RFR). Gamma Knife radiosurgery (GKRS) is a considerable option for patients with pain recurrence after an initial procedure. This study was undertaken to analyze the effects of gamma knife radiosurgery in recurrent TN after other procedures. METHODS: Eleven recurrent TN patients after other procedures underwent GKRS in our hospital from September 2004 to August 2016. Seven patients had previously undergone MVD alone, two underwent MVD with partial sensory rhizotomy (PSR), and two underwent RFR. Mean patient age was 60.5 years. We retrospectively analyzed patient's characteristics, clinical results, sites, and divisions of pain. Outcomes were evaluated using the Visual Analog Scales (VAS) score. RESULTS: Right sides were more prevalent than left sides (7:4). The most common distribution of pain was V1 + V2 division (n = 5) following V2 + V3 (n = 3), V2 (n = 2), and V1 + V2 + V3 (n = 1) division. Median GKRS dose was 80 Gy and the mean interval between the prior treatment and GKRS was 74.45 months. The final outcomes of subsequent GKRS were satisfactory in most cases, and at 12 months postoperatively ten patients (90.0%) had a VAS score of ≤ 3. CONCLUSIONS: In this study, the clinical result of GKRS was satisfactory. Invasive procedures, such as, MVD, RFR are initially effective in TN patients, but GKRS provides a safe and satisfactory treatment modality for those who recurred after prior invasive treatments.
		                        		
		                        		
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Microvascular Decompression Surgery
		                        			;
		                        		
		                        			Radiosurgery
		                        			;
		                        		
		                        			Recurrence
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Rhizotomy
		                        			;
		                        		
		                        			Trigeminal Nerve
		                        			;
		                        		
		                        			Trigeminal Neuralgia
		                        			;
		                        		
		                        			Visual Analog Scale
		                        			
		                        		
		                        	
3.Clinical observation of selective posterior rhizotomy for improving spasticity and gross movement in patients with cerebral palsy.
Jie XU ; Lin XU ; Jie ZENG ; Xing-Kui YANG ; Zhao-Hui LI ; Gao-Kai SHAO ; Xiao-Ye LI ; Bo-Wen DENG ; Xiao-Hong MU
China Journal of Orthopaedics and Traumatology 2019;32(9):815-819
		                        		
		                        			OBJECTIVE:
		                        			To explore the effect of selective lumbosacral posterior rhizotomy(SPR) on lower limb spasticity and gross motor function in patients with cerebral palsy.
		                        		
		                        			METHODS:
		                        			From January 2018 to October 2018, 47 patients with cerebral palsy were treated with rehabilitation alone and SPR combined with rehabilitation. According to whether SPR was performed, the patients were divided into group A and group B. Group A was treated with rehabilitation combined with SPR at lumbosacral level, and group B was treated with rehabilitation alone. There were 23 cases in group A, including 15 males and 8 females, with an average age of (7.30±3.25) years old; 24 cases in group B, 13 males and 11 females, with an average age of (7.00±3.09) years old. Forty-seven patients were assessed with modified Ashworth(MAS) and Gross Motor Function Scale(GMFM-88 items) before and after treatment. The changes of MAS and GMFM-88 scores before and after treatment were compared to evaluate the degree of spasm and the improvement of gross motor function in the two groups.
		                        		
		                        			RESULTS:
		                        			All 47 patients were followed up. At 6 months after treatment, the MAS classification of the two groups was significantly improved(<0.05), and the improvement of group A was more obvious than that of group B(<0.05). Six months after treatment, the D, E and total scores of GMFM-88 between two groups were significantly improved compared with those before operation(<0.05). The improvement of D and total scores in group A was more obvious than that in group B. There was no significant difference in the improvement of area E between two groups.
		                        		
		                        			CONCLUSIONS
		                        			Selective posterior rhizotomy combined with rehabilitation can significantly improve the spastic state and gross motor function of lower limbs in children with cerebral palsy, and can effectively promote the reconstruction and recovery of motor function of lower limbs in children with cerebral palsy.
		                        		
		                        		
		                        		
		                        			Cerebral Palsy
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Child, Preschool
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lower Extremity
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Movement
		                        			;
		                        		
		                        			Muscle Spasticity
		                        			;
		                        		
		                        			Rhizotomy
		                        			
		                        		
		                        	
4.Cost of Rehabilitation Treatment of Patients With Cerebral Palsy in Korea.
Seong Woo KIM ; Ha Ra JEON ; Taemi YOUK ; Jiyong KIM
Annals of Rehabilitation Medicine 2018;42(5):722-729
		                        		
		                        			
		                        			OBJECTIVE: To investigate rehabilitation treatment cost of patients with cerebral palsy (CP) according to age. METHODS: We analyzed the cost of rehabilitation treatment from 2007 to 2013 for patients diagnosed with CP by sourcing data from the National Health Information Database. RESULTS: While the number of recently born children requiring rehabilitation treatment has decreased, the number of patients requiring this treatment in other age groups has gradually increased. In addition, annual physical therapy, occupational therapy, hydrotherapy, and botulinum toxin injection treatment costs per person have increased. On the other hand, the number of orthopedic surgeries and selective dorsal rhizotomy performed has decreased. CONCLUSION: This study investigated trends in the cost of treatment for patients with CP. This study can be used as a basis to provide treatment support for patients with CP.
		                        		
		                        		
		                        		
		                        			Botulinum Toxins
		                        			;
		                        		
		                        			Cerebral Palsy*
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Hand
		                        			;
		                        		
		                        			Health Care Costs
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hydrotherapy
		                        			;
		                        		
		                        			Korea*
		                        			;
		                        		
		                        			Occupational Therapy
		                        			;
		                        		
		                        			Orthopedics
		                        			;
		                        		
		                        			Rehabilitation*
		                        			;
		                        		
		                        			Rhizotomy
		                        			
		                        		
		                        	
5.Microvascular Decompression for Glossopharyngeal Neuralgia: Clinical Analyses of 30 Cases.
Mi Kyung KIM ; Jae Sung PARK ; Young Hwan AHN
Journal of Korean Neurosurgical Society 2017;60(6):738-748
		                        		
		                        			
		                        			OBJECTIVE: We present our experience of microvascular decompression (MVD) for glossopharyngeal neuralgia (GPN) and evaluate the postoperative outcomes in accordance with four different operative techniques during MVD. METHODS: In total, 30 patients with intractable primary typical GPN who underwent MVD without rhizotomy and were followed for more than 2 years were included in the analysis. Each MVD was performed using one of four different surgical techniques: interposition of Teflon pieces, transposition of offending vessels using Teflon pieces, transposition of offending vessels using a fibrin-glue-coated Teflon sling, and removal of offending veins. RESULTS: The posterior inferior cerebellar artery was responsible for neurovascular compression in 27 of 30 (90%) patients, either by itself or in combination with other vessels. The location of compression on the glossopharyngeal nerve varied; the root entry zone (REZ) only (63.3%) was most common, followed by both the REZ and distal portion (26.7%) and the distal portion alone (10.0%). In terms of detailed surgical techniques during MVD, the offending vessels were transposed in 24 (80%) patients, either using additional insulation, offered by Teflon pieces (15 patients), or using a fibrin glue-coated Teflon sling (9 patients). Simple insertion of Teflon pieces and removal of a small vein were also performed in five and one patient, respectively. During the 2 years following MVD, 29 of 30 (96.7%) patients were asymptomatic or experienced only occasional pain that did not require medication. Temporary hemodynamic instability occurred in two patients during MVD, and seven patients experienced transient postoperative complications. Neither persistent morbidity nor mortality was reported. CONCLUSION: This study demonstrates that MVD without rhizotomy is a safe and effective treatment option for GPN.
		                        		
		                        		
		                        		
		                        			Arteries
		                        			;
		                        		
		                        			Fibrin
		                        			;
		                        		
		                        			Glossopharyngeal Nerve
		                        			;
		                        		
		                        			Glossopharyngeal Nerve Diseases*
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Microvascular Decompression Surgery*
		                        			;
		                        		
		                        			Mortality
		                        			;
		                        		
		                        			Neuralgia
		                        			;
		                        		
		                        			Polytetrafluoroethylene
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			Rhizotomy
		                        			;
		                        		
		                        			Veins
		                        			
		                        		
		                        	
6.A Clinical Analysis of Secondary Surgery in Trigeminal Neuralgia Patients Who Failed Prior Treatment.
Il Ho KANG ; Bong Jin PARK ; Chang Kyu PARK ; Hridayesh Pratap MALLA ; Sung Ho LEE ; Bong Arm RHEE
Journal of Korean Neurosurgical Society 2016;59(6):637-642
		                        		
		                        			
		                        			OBJECTIVE: Although many treatment modalities have been introduced for trigeminal neuralgia (TN), the long-term clinical results remain unsatisfactory. It has been particularly challenging to determine an appropriate treatment strategy for patients who have responded poorly to initial therapies. We analyzed the surgical outcomes in TN patients who failed prior treatments. METHODS: We performed a retrospective analysis of 37 patients with recurrent or persistent TN symptoms who underwent surgery at our hospital between January 2010 and December 2014. Patients with follow-up data of at least one year were included. The prior treatment modalities of the 37 patients included microvascular decompression (MVD), gamma knife radiosurgery (GKRS), and percutaneous procedures such as radiofrequency rhizotomy (RFR), balloon compression, and glycerol rhizotomy (GR). The mean follow-up period was 69.9 months (range : 16–173). The mean interval between the prior treatment and second surgery was 26 months (range : 7–123). We evaluated the surgical outcomes using the Barrow Neurological Institute (BNI) pain intensity scale. RESULTS: Among the 37 recurrent or persistent TN patients, 22 underwent MVD with partial sensory rhizotomy (PSR), 8 received MVD alone, and 7 had PSR alone. Monitoring of the surgical treatment outcomes via the BNI pain intensity scale revealed 8 (21.6%) patients with a score of I, 13 (35.1%) scoring II, 13 (35.1%) scoring III, and 3 (8.2%) scoring IV at the end of the follow-up period. Overall, 91.8% of patients had good surgical outcomes. With regard to postoperative complications, 1 patient had transient cerebrospinal fluid rhinorrhea (2.7%), another had a subdural hematoma (2.7%), and facial sensory changes were noted in 8 (21.1%) patients after surgery. CONCLUSION: Surgical interventions, such as MVD and PSR, are safe and very effective treatment modalities in TN patients who failed initial or prior treatments. We presume that the combination of MVD with PSR enabled us to obtain good short- and long-term surgical outcomes. Therefore, aggressive surgical treatment should be considered in patients with recurrent TN despite failure of various treatment modalities.
		                        		
		                        		
		                        		
		                        			Cerebrospinal Fluid Rhinorrhea
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Glycerol
		                        			;
		                        		
		                        			Hematoma, Subdural
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Microvascular Decompression Surgery
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			Radiosurgery
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Rhizotomy
		                        			;
		                        		
		                        			Trigeminal Neuralgia*
		                        			
		                        		
		                        	
7.Radiofrequency Sacral Rhizotomy for the Management of Intolerable Neurogenic Bladder in Spinal Cord Injured Patients.
Annals of Rehabilitation Medicine 2012;36(2):213-219
		                        		
		                        			
		                        			OBJECTIVE: To investigate the effect of radiofrequency (RF) sacral rhizotomy of the intolerable neurogenic bladder in spinal cord injured patients. METHOD: Percutaneous RF sacral rhizotomy was performed on 12 spinal cord injured patients who had neurogenic bladder manifested with urinary incontinence resisted to an oral and intravesical anticholinergic instillation treatment. Various combinations of S2, S3, and S4 RF rhizotomies were performed. The urodynamic study (UDS) was performed 1 week before RF rhizotomy. The voiding cystourethrogram (VCUG) and voiding diaries were compared 1 week before and 4 weeks after therapy. Total volume of daily urinary incontinence (ml/day) and clean intermittent catheterization (ml/time) volume of each time were also monitored. RESULTS: After RF sacral rhizotomy, bladder capacity increased in 9 patients and the amount of daily urinary incontinence decreased in 11 patients. The mean maximal bladder capacity increased from 292.5 to 383.3 ml (p<0.05) and mean daily incontinent volume decreased from 255 to 65 ml (p<0.05). Bladder trabeculation and vesicoureteral reflux findings did not change 4 weeks after therapy. CONCLUSION: This study revealed that RF sacral rhizotomy was an effective method for neurogenic bladder with uncontrolled incontinence using conventional therapy among spinal cord injured patients.
		                        		
		                        		
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intermittent Urethral Catheterization
		                        			;
		                        		
		                        			Rhizotomy
		                        			;
		                        		
		                        			Spinal Cord
		                        			;
		                        		
		                        			Spinal Cord Injuries
		                        			;
		                        		
		                        			Urinary Bladder
		                        			;
		                        		
		                        			Urinary Bladder, Neurogenic
		                        			;
		                        		
		                        			Urinary Incontinence
		                        			;
		                        		
		                        			Urodynamics
		                        			;
		                        		
		                        			Vesico-Ureteral Reflux
		                        			
		                        		
		                        	
8.Trigeminal Neuralgia and Neural Blockade.
Hanyang Medical Reviews 2011;31(2):63-69
		                        		
		                        			
		                        			Trigeminal neuralgia is characterized by recurrent episodes of intense lancinating pain affecting the face localized to the sensory supply areas of the trigeminal nerve. There is a lack of certainty regarding the etiology and pathophysiology of trigeminal neuralgia. The diagnosis of idiopathic typical trigeminal neuralgia requires the absence of clinically evident neurological deficit. Treatment must be individualized to each patient. Various trigeminal neural blockades can be options when medical therapy fails to relieve pain. Neural blockades include peripheral nerve branch blocks and intracranial nerve root or ganglion blocks such as RF thermocoagulation, percutaneous balloon compression and glycerol rhizolysis. Neural blockade with local anesthetics produces temporary effects, but neural blockade with neurolytics like alcohol lasts longer, around one or two years. They are very useful for patients with poor general condition or high risk. RF rhizotomy and balloon compression of trigeminal ganglion are relatively more invasive treatment options, but have more cost effectiveness with less serious complications compared to other surgical procedures. The continuous improvement of neural block techniques is necessary for better treatment of trigeminal neuralgia.
		                        		
		                        		
		                        		
		                        			Anesthetics, Local
		                        			;
		                        		
		                        			Cost-Benefit Analysis
		                        			;
		                        		
		                        			Electrocoagulation
		                        			;
		                        		
		                        			Ganglion Cysts
		                        			;
		                        		
		                        			Glycerol
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Peripheral Nerves
		                        			;
		                        		
		                        			Rhizotomy
		                        			;
		                        		
		                        			Trigeminal Ganglion
		                        			;
		                        		
		                        			Trigeminal Nerve
		                        			;
		                        		
		                        			Trigeminal Neuralgia
		                        			
		                        		
		                        	
9.Radiofrequency thermocoagulation rhizotomy for recurrent trigeminal neuralgia after microvascular decompression.
Liang-Wen ZHANG ; Yu-Guang LIU ; Cheng-Yuan WU ; Shu-Jun XU ; Shu-Gan ZHU
Chinese Medical Journal 2011;124(22):3726-3730
BACKGROUNDMicrovascular decompression (MVD) is a well accepted surgical treatment strategy for trigeminal neuralgia (TN) with satisfying long-term outcome. However, considerable recurrent patients need more effective management. The purpose of this study was to evaluate the effectiveness of radiofrequency thermocoagulation rhizotomy (RTR) on patients with recurrent TN after MVD.
METHODSTotally 62 cases of recurrent TN after MVD undergoing RTR from January 2000 to January 2010 were retrospectively evaluated. Based on surgical procedures undertaken, these 62 cases were classified into two subgroups: group A consisted of 23 cases that underwent traditional RTR by free-hand; group B consisted of 39 cases that underwent RTR under the guidance of virtual reality imaging technique or neuronavigation system. The patients in group A were followed up for 14 to 70 months (mean, 40 ± 4), and those in group B were followed up for 13 to 65 months (mean, 46 ± 7). Kaplan-Meier analyses of the pain-free survival curves were used for the censored survival data, and the log-rank test was used to compare survival curves of the two groups.
RESULTSAll patients in both groups A and B attained immediate pain relief after RTR. Both groups attained good pain relief rate within the first two years of follow-up: 92.3%, 84.6% and 82.6%, 69.6% respectively (P > 0.05). After 2 years, the virtual reality or neuronavigation assisted RTR group (group B) demonstrated higher pain relief rates of 82.5%, 76.2% and 68.8% at 3, 4 and 5 years after operation respectively, while those in group A was 57.2%, 49.6%, and 36.4% (P < 0.05). Low levels of minor complications were recorded, while neither mortalities nor significant morbidity was documented.
CONCLUSIONSRTR was effective in alleviating the pain of TN cases suffering from unsuccessful MVD management. With the help of virtual reality imaging technique or neuronavigation system, the patients could attain better long-term pain relief.
Adult ; Aged ; Electrocoagulation ; methods ; Female ; Humans ; Male ; Microvascular Decompression Surgery ; Middle Aged ; Radiosurgery ; methods ; Retrospective Studies ; Rhizotomy ; methods ; Treatment Outcome ; Trigeminal Neuralgia ; surgery ; therapy
10.Comprasion of Effectiveness of CT vs C-arm Guided Percutaneous Radiofrequency Lumbar Facet Rhizotomy.
The Korean Journal of Pain 2010;23(2):137-141
		                        		
		                        			
		                        			BACKGROUND: Facet joint have been implicated as a source of chronic low back pain. Radiofrequency denervation has demonstrated the most solid evidence. To increase safety and efficacy of treatment, computed tomography (CT) guidance injection has been used in several disease. The purpose of this study was to evaluate the efficacy of CT-guided radiofrequency rhizotomy in the treatment of facet joint pain. METHODS: A total of 40 patients were randomized to undergo radiofrequency facet joint denervation under CT guidance or C-arm guidance. All patients were examined visual analogue scale (VAS) score before treatment, 1 month, and 3 months after treatment. RESULTS: The VAS in both groups showed significant improvement over the 1-month interval. No significant difference in the VAS score among the group was observed. CONCLUSIONS: In this study there was no significant difference between CT guidance lumbar rhizotomy and C-arm guidance lumbar rhizotomy. Therefore CT-guided radiofrequency denervation of the lumbar facet joint was a minimally invasive technique that appears effective.
		                        		
		                        		
		                        		
		                        			Denervation
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Low Back Pain
		                        			;
		                        		
		                        			Rhizotomy
		                        			;
		                        		
		                        			Zygapophyseal Joint
		                        			
		                        		
		                        	
            
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