1.Oral panorama reconstruction method based on pre-segmentation and Bezier function.
Changpeng HOU ; Fudong ZHU ; Gaohua ZHANG ; Zhen LYU ; Yunfeng LIU ; Weidong ZHU
Journal of Biomedical Engineering 2023;40(5):894-902
For patients with partial jaw defects, cysts and dental implants, doctors need to take panoramic X-ray films or manually draw dental arch lines to generate Panorama images in order to observe their complete dentition information during oral diagnosis. In order to solve the problems of additional burden for patients to take panoramic X-ray films and time-consuming issue for doctors to manually segment dental arch lines, this paper proposes an automatic panorama reconstruction method based on cone beam computerized tomography (CBCT). The V-network (VNet) is used to pre-segment the teeth and the background to generate the corresponding binary image, and then the Bezier curve is used to define the best dental arch curve to generate the oral panorama. In addition, this research also addressed the issues of mistakenly recognizing the teeth and jaws as dental arches, incomplete coverage of the dental arch area by the generated dental arch lines, and low robustness, providing intelligent methods for dental diagnosis and improve the work efficiency of doctors.
Humans
;
Radiography, Panoramic/methods*
;
Cone-Beam Computed Tomography/methods*
;
Head
;
Image Processing, Computer-Assisted/methods*
2.Influence of axial rotation on measurement of medial proximal tibial angle.
Rui-Yong DU ; Sha WU ; Qi MA ; Pu LIU ; Feng JING ; Xu CAI
China Journal of Orthopaedics and Traumatology 2023;36(12):1165-1168
OBJECTIVE:
To measure and compare medial proximal tibial angle (MPTA) of lower limbs under different axial rotation angles(neutral position, 30° internal rotation, 30° external rotation) on the load position radiographs, and explore changes and significance of MPTA measured within and between groups of tibia at different axial rotation positions.
METHODS:
From January 2018 to December 2018, 40 patients with knee osteoarthritis (KOA) were selected, with a total of 80 limbs, including 12 males and 28 females, aged from 29 to 73 years old with an average of (59.6±12.7) years old. Full length radiographs of the lower limbs were taken on neutral tibia position, 30° internal rotation and 30° external rotation, respectively. MPTA was measured and the results were compared between groups and within groups.
RESULTS:
MPTA measured on the left lower extremity of neutral tibia, 30° internal rotation and 30° external rotation were (86.08±2.48) °, (88.62±2.94) ° and (83.47±3.10) °, respectively. MPTA measured on the right lower limb were (86.87±1.97) °, (89.02±2.39) ° and (83.80±2.77) °, respectively, and there were no significant difference in MPTA measured between rotation angle group (P>0.05). While there were statistical difference in MPTA on the same limb between groups (P<0.05). On 30° internal rotation, MPTA of left and right lower limbs increased by (2.54±1.74) ° and (2.15±1.78) ° compared with tibia neutral position. On 30° external rotation, MPTA of left and right lower limbs decreased (2.61±2.03) ° and (3.07±1.75) ° compared with tibial neutral position.
CONCLUSION
When a full-length X-ray film is taken on the weight-bearing position of both lower limbs, if there is axial rotation or external rotation of tibia, MPTA will increase or decrease compared with neutral position, which may cause a certain degree of deviation in clinical operation based on the accurate measurement of MPTA. However, the extent to which this bias affects the clinical operation effect remains to be verified. In addition, limited by the total number of samples and the number of measurement groups, whether there is a linear relationship between MPTA deviation and tibial axial rotation needs to be further studied.
Male
;
Female
;
Humans
;
Adult
;
Middle Aged
;
Aged
;
Tibia/surgery*
;
Lower Extremity
;
Osteoarthritis, Knee/surgery*
;
Radiography
;
Osteotomy/methods*
;
Knee Joint/surgery*
;
Retrospective Studies
3.The performance of digital chest radiographs in the detection and diagnosis of pulmonary nodules and the consistency among readers.
Min LIANG ; Shi Jun ZHAO ; Li Na ZHOU ; Xiao Juan XU ; Ya Wen WANG ; Lin NIU ; Hui Hui WANG ; Wei TANG ; Ning WU
Chinese Journal of Oncology 2023;45(3):265-272
Objective: To investigate the detection and diagnostic efficacy of chest radiographs for ≤30 mm pulmonary nodules and the factors affecting them, and to compare the level of consistency among readers. Methods: A total of 43 patients with asymptomatic pulmonary nodules who consulted in Cancer Hospital, Chinese Academy of Medical Sciences from 2012 to 2014 and had chest CT and X-ray chest radiographs during the same period were retrospectively selected, and one nodule ≤30 mm was visible on chest CT images in the whole group (total 43 nodules in the whole group). One senior radiologist with more than 20 years of experience in imaging diagnosis reviewed CT images and recording the size, morphology, location, and density of nodules was selected retrospectively. Six radiologists with different levels of experience (2 residents, 2 attending physicians and 2 associate chief physicians independently reviewed the chest images and recorded the time of review, nodule detection, and diagnostic opinion. The CT imaging characteristics of detected and undetected nodules on X images were compared, and the factors affecting the detection of nodules on X-ray images were analyzed. Detection sensitivity and diagnosis accuracy rate of 6 radiologists were calculated, and the level of consistency among them was compared to analyze the influence of radiologists' seniority and reading time on the diagnosis results. Results: The number of nodules detected by all 6 radiologists was 17, with a sensitivity of detection of 39.5%(17/43). The number of nodules detected by ≥5, ≥4, ≥3, ≥2, and ≥1 physicians was 20, 21, 23, 25, and 28 nodules, respectively, with detection sensitivities of 46.5%, 48.8%, 53.5%, 58.1%, and 65.1%, respectively. Reasons for false-negative result of detection on X-ray images included the size, location, density, and morphology of the nodule. The sensitivity of detecting ≤30 mm, ≤20 mm, ≤15 mm, and ≤10 mm nodules was 46.5%-58.1%, 45.9%-54.1%, 36.0%-44.0%, and 36.4% for the 6 radiologists, respectively; the diagnosis accuracy rate was 19.0%-85.0%, 16.7%-6.5%, 18.2%-80.0%, and 0%-75.0%, respectively. The consistency of nodule detection among 6 doctors was good (Kappa value: 0.629-0.907) and the consistency of diagnostic results among them was moderate or poor (Kappa value: 0.350-0.653). The higher the radiologist's seniority, the shorter the time required to read the images. The reading time and the seniority of the radiologists had no significant influence on the detection and diagnosis results (P>0.05). Conclusions: The ability of radiographs to detect lung nodules ≤30 mm is limited, and the ability to determine the nature of the nodules is not sufficient, and the increase in reading time and seniority of the radiologists will not improve the diagnostic accuracy. X-ray film exam alone is not suitable for lung cancer diagnosis.
Humans
;
Retrospective Studies
;
Solitary Pulmonary Nodule/diagnostic imaging*
;
Radiography
;
Multiple Pulmonary Nodules/diagnostic imaging*
;
Tomography, X-Ray Computed/methods*
;
Lung Neoplasms/diagnostic imaging*
;
Sensitivity and Specificity
;
Radiographic Image Interpretation, Computer-Assisted/methods*
4.Research Progress in Diagnostic Reference Levels in Interventional Radiology.
Pei-Yi QIAN ; Yun LIU ; Jia REN ; Xiao-Jun XU ; Zhi-Xin ZHAO ; Cheng-Jian CAO ; Lei YANG
Acta Academiae Medicinae Sinicae 2023;45(3):506-511
During interventional procedures,subjects are exposed to direct and scattered X-rays.Establishing diagnostic reference levels is an ideal way to optimize the radiation dose and reduce radiation hazard.In recent years,diagnostic reference levels in interventional radiology have been established in different countries.However,because of the too many indicators for characterizing the radiation dose,the indicators used to establish diagnostic reference levels vary in different countries.The research achievements in this field remain to be reviewed.We carried out a retrospective analysis of the definition,establishment method,application,and main factors influencing the dose difference of the diagnostic reference level,aiming to provide a basis for establishing the diagnostic reference level for interventional procedures in China.
Humans
;
Diagnostic Reference Levels
;
Radiology, Interventional/methods*
;
Radiation Dosage
;
Retrospective Studies
;
Radiography
5.Effectiveness validation of a novel comprehensive classification for intertrochanteric fractures.
Lukuan CUI ; Hao LIU ; Jiangjing WANG ; Huanhuan FAN ; Dapeng WANG ; Shuhui WANG ; Chi SONG
Chinese Journal of Reparative and Reconstructive Surgery 2023;37(4):417-422
OBJECTIVE:
To validate the effectiveness of a novel comprehensive classification for intertrochanteric fracture (ITF).
METHODS:
The study included 616 patients with ITF, including 279 males (45.29%) and 337 females (54.71%); the age ranged from 23 to 100 years, with an average of 72.5 years. Two orthopaedic residents (observers Ⅰ and Ⅱ) and two senior orthopaedic surgeons (observers Ⅲ and Ⅳ) were selected to classify the CT imaging data of 616 patients in a random order by using the AO/Orthopaedic Trauma Association (AO/OTA) classification of 1996/2007 edition, the AO/OTA classification of 2018 edition, and the novel comprehensive classification method at an interval of 1 month. Kappa consistency test was used to evaluate the intra-observer and inter-observer consistency of the three ITF classification systems.
RESULTS:
The inter-observer consistency of the three classification systems evaluated by 4 observers twice showed that the 3 classification systems had strong inter-observer consistency. Among them, the κ value of the novel comprehensive classification was higher than that of the AO/OTA classification of 1996/2007 edition and 2018 edition, and the experience of observers had a certain impact on the classification results, and the inter-observer consistency of orthopaedic residents was slightly better than that of senior orthopaedic surgeons. The intra-observer consistency of two evaluations of three classification systems by 4 observers showed that the consistency of the novel comprehensive classification was better for the other 3 observers, except that the consistency of observer Ⅳ in the AO/OTA classification of 2018 version was slightly higher than that of the novel comprehensive classification. The results showed that the novel comprehensive classification has higher repeatability, and the intra-observer consistency of senior orthopaedic surgeons was better than that of orthopaedic residents.
CONCLUSION
The novel comprehensive classification system has good intra- and inter-observer consistency, and has high validity in the classification of CT images of ITF patients; the experience of observers has a certain impact on the results of the three classification systems, and those with more experiences have higher intra-observer consistency.
Male
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Female
;
Humans
;
Young Adult
;
Adult
;
Middle Aged
;
Aged
;
Aged, 80 and over
;
Observer Variation
;
Reproducibility of Results
;
Hip Fractures/surgery*
;
Tomography, X-Ray Computed/methods*
;
Radiography
6.Research on panoramic image reconstruction based on oral cone beam computed tomography.
Jianguo ZHANG ; Yichuan JIANG ; Fei GAO ; Sheng ZHAO ; Liang SONG
Journal of Biomedical Engineering 2022;39(5):870-875
During the automatic reconstruction of panoramic images, the effect of dental arch curve fitting will affect the integrity of the content of the panoramic image. Metal implants in the patient's mouth usually lead to a decrease in the contrast of the panoramic image, which affects the doctor's diagnosis. In this paper, an automatic oral panoramic image reconstruction method was proposed. By calculating key image areas and image extraction fusion algorithms, the dental arch curve could be automatically detected and adjusted on a small number of images, and the intensity distribution of teeth, bone tissue and metal implants on the image could be adjusted to reduce the impact of metal on other tissues, to generate high-quality panoramic images. The method was tested on 50 cases of cone beam computed tomography (CBCT) data with good results, which can effectively improve the quality of panoramic images.
Humans
;
Radiography, Panoramic/methods*
;
Cone-Beam Computed Tomography/methods*
;
Tooth
;
Algorithms
;
Image Processing, Computer-Assisted/methods*
7.Minimally invasive osteotomy with absorbable screws in treating hallux valgus deformity.
Qin-Meng YANG ; Xiao-Yong FU ; Guo-Jie LIN ; Jin-Song HONG
China Journal of Orthopaedics and Traumatology 2022;35(9):836-842
OBJECTIVE:
To evaluate clnical effect of minimally invasive osteotomy with absorbable screws in treating hallux valgus deformity.
METHODS:
Clnical data of 31 patients with hallux valgus deformity were retrospective analyzed from January 2019 to December 2020, and divided into absorbable screws group (17 patients) and titanium cannulated screw group (14 patients). In absorbable screws group, there were 1 male and 16 females aged from 32 to 72 years old with an average of (54.53±12.12) years old;6 patients on the left side, 5 on bilateral and 6 on the right side;1 patient was mild, 11 moderate and 5 severe;treated with minimally invasive osteotomy and fixation of absorbable screws. In titanium cannulated screw group, there were 2 males and 12 females aged from 18 to 71 years old with an average of (47.57±15.68) years old;4 patients on the left side, 4 on bilateral and 6 on the right side;1 patient was mild, 9 moderate and 4severe;treated with minimally invasive osteotomy and fixation of titanium cannulated screw. Complications between two groups were observed, changes of hallux valgus angle (HVA)and intermetatarsal angle (IMA)were detected and compared before and after operation at 12 months, American Orthopedic Foot and Ankle Society(AOFAS) and visual analogue scale(VAS) before and after operation at 12 months were also compared.
RESULTS:
All 31 patients were followed up from 13 to 20 months with an average of (16.61±2.47) months. Patients in absorbable screws group were followed up from 14 to 20 months with an average of (16.88±2.80) months, while patients in titanium cannulated screw group were followed up from 13 to 19 months with an average of (16.29±2.05) months;there was no difference between two groups(P>0.05). One patient in absorbable screws group occurred numbness around incision, 3 patients in titanium cannulated screw group occurred complications, including numbness around incision in 1 patient, skin irritation due to internal fixation in 1 patient, and recurrence in 1 case;there was no statistic difference between two groups (χ2=1.651, P=0.199). There were no statistic difference in HVA and IMA between two groups before and after operation at 12 months(P>0.05). There were no statistic difference between two groups in AOFAS and VAS before and after operation at 12 months(P>0.05).
CONCLUSION
Compare with mainstream fixation with titanium hollow screw after minmally invasive osteotomy, fixation with absorbable screw could achieve comparable clinical outcome on the basis of images and function evaluation.
Adolescent
;
Adult
;
Aged
;
Bunion
;
Female
;
Hallux Valgus/surgery*
;
Humans
;
Hypesthesia
;
Male
;
Metatarsal Bones/surgery*
;
Middle Aged
;
Osteotomy/methods*
;
Radiography
;
Retrospective Studies
;
Titanium
;
Young Adult
8.Rotating Scarf osteotomy in treating hallux valgus combined with the first metatarsal rotation.
Wei-Xin ZHENG ; Jie YANG ; Yi LI ; Xiao-Jun LIANG ; Jun-Hu WANG ; Yang DU ; Xin-Wen WANG
China Journal of Orthopaedics and Traumatology 2022;35(12):1138-1141
OBJECTIVE:
To explore clinical effect of rotational Scarf osteotomy in treating hallux valgus (HV) with rotation of the first metatarsal bone.
METHODS:
From January 2018 to October 2019, 35 patients (40 feet) with HV and rotation deformity of the first metatarsal were treated with rotational Scarf osteotomy, including 5 males and 30 females;aged from 25 to 76 years old with an average of (40.32±5.43) years old. Hallux valgus angle(HVA), intermetatarsal angle (IMA), distal metatarsal articular angle (DMAA), the first metatarsal length (FML) were observed and compared, American Orthopedic Foot and Ankle Society(AOFAS) of hallux metatarsophalangeal interphalangeal joint score and visual analogue scale (VAS) were used to evaluate functional evaluation.
RESULTS:
Thirty-five patients(40 feet) were followed up from 12 to 36 months with an average of (14.35±3.62) months. HVA, IMA and DMAA were corrected from (36.32±4.51) °, (14.21±3.22) ° and (28.35±4.32) ° before operation to (14.32±5.71) °, (5.83±3.97) ° and (7.32±2.14) ° after operation respectively (P<0.05). There was no satistical difference in FML before and after operation (P>0.05). AOFAS score and VAS improved from (57.00±4.31) and (6.00±1.21) before operation to (90.31±3.28) and (1.42±0.83) after operation, respectively, and had significant difference(P<0.05);according to AOFAS score, 23 feet got excellent results, 15 feet good and 2 feet fair.
CONCLUSION
Rotational Scarf osteotomy with strong correction and high dimension could effectively correct HV combined with rotation deformity of the first metatarsal bone, improve function of the forefoot, and obtain good clinical results.
Male
;
Female
;
Humans
;
Adult
;
Middle Aged
;
Aged
;
Hallux Valgus/diagnostic imaging*
;
Metatarsal Bones/surgery*
;
Fluorometholone
;
Rotation
;
Treatment Outcome
;
Radiography
;
Bunion
;
Osteotomy/methods*
9.Thoughts on Traditional Chinese Medicine Treatment of Novel Coronavirus Pneumonia Based on Two Cases.
Jie MA ; Hua-Yang WU ; Yu-Zhu CHEN ; Mao HUANG ; Li-Shan ZHANG
Chinese journal of integrative medicine 2021;27(5):375-378
Adult
;
Body Temperature/drug effects*
;
COVID-19/pathology*
;
Drug Therapy, Combination
;
Drugs, Chinese Herbal/therapeutic use*
;
Ephedra sinica/chemistry*
;
Female
;
Fever/pathology*
;
Glycyrrhiza/chemistry*
;
Humans
;
Indoles/administration & dosage*
;
Male
;
Medicine, Chinese Traditional/methods*
;
Middle Aged
;
Phytotherapy/methods*
;
Pneumonia, Viral/pathology*
;
Radiography, Thoracic
;
SARS-CoV-2/drug effects*

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