1.Fibrosing Mediastinitis: a Rare Cause of Unilateral Absent Lung Perfusion on a V/Q Scan
Alyssa R GOLDBACH ; Suzanne PASCARELLA ; Simin DADPRAVARAR
Nuclear Medicine and Molecular Imaging 2018;52(5):401-404
		                        		
		                        			
		                        			We report a case of a 29-year-old female with a history of asthma, post-partumARDS, and pulmonary hypertension who presents with severe shortness of breath. The patient describes her shortness of breath as progressive over the past 10 years. Chest radiography and CT angiography of the thorax showed findings consistent with fibrosing mediastinitis with severe stenosis of the left main pulmonary artery. This resulted in appearance of unilateral absent left lung perfusion on quantitative Tc-99-MAA perfusion and Xe-133 ventilation (V/Q) scan.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Angiography
		                        			;
		                        		
		                        			Asthma
		                        			;
		                        		
		                        			Constriction, Pathologic
		                        			;
		                        		
		                        			Dyspnea
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Histoplasma
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypertension, Pulmonary
		                        			;
		                        		
		                        			Lung
		                        			;
		                        		
		                        			Mediastinitis
		                        			;
		                        		
		                        			Perfusion
		                        			;
		                        		
		                        			Pulmonary Artery
		                        			;
		                        		
		                        			Radiography
		                        			;
		                        		
		                        			Thorax
		                        			;
		                        		
		                        			Ventilation
		                        			
		                        		
		                        	
2.Clinics in diagnostic imaging (186). Atrial septal defect with pulmonary arterial hypertension.
Li Ching LAU ; Hui Liang KOH ; Wei Luen James YIP ; Ching Ching ONG
Singapore medical journal 2018;59(5):279-283
		                        		
		                        			
		                        			We report a case of a 61-year-old woman with a large atrial septal defect (ASD) that was detected incidentally on chest radiography and computed tomography when she presented with sepsis. Echocardiography confirmed a large secundum ASD with left-to-right shunt flow, right heart dilatation and severe pulmonary hypertension. The patient had a poor clinical outcome despite intensive care and eventually passed away. Haemodynamically significant ASDs have a known association with increased morbidity and mortality, and their early detection and closure cannot be understated. This article aimed to highlight the imaging features of ASD, with special emphasis on the routine chest radiograph. The pathophysiology and clinical manifestations of ASD are also briefly discussed.
		                        		
		                        		
		                        		
		                        			Cardiomegaly
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Critical Care
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Heart Septal Defects, Atrial
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypertension, Pulmonary
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Patient Admission
		                        			;
		                        		
		                        			Pulmonary Artery
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Radiography, Abdominal
		                        			;
		                        		
		                        			Radiography, Thoracic
		                        			;
		                        		
		                        			Sepsis
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
3.A Case of Multiple Cardiovascular and Tracheal Anomalies Presented with Wolff-Parkinson-White Syndrome in a Middle-aged Adult.
Hyejin SHI ; Sungmin SOHN ; SungHo WANG ; Sungrock PARK ; SangKi LEE ; Song Yi KIM ; Sun Young JEONG ; Changhwan KIM
Journal of Korean Medical Science 2017;32(12):2069-2072
		                        		
		                        			
		                        			Congenital cardiovascular anomalies, such as dextrocardia, persistent left superior vena cava (SVC), and pulmonary artery (PA) sling, are rare disorders. These congenital anomalies can occur alone, or coincide with other congenital malformations. In the majority of cases, congenital anomalies are detected early in life by certain signs and symptoms. A 56-year-old man with no previous medical history was admitted due to recurrent wide QRS complex tachycardia with hemodynamic collapse. A chest radiograph showed dextrocardia. After synchronized cardioversion, an electrocardiogram revealed Wolff-Parkinson-White (WPW) syndrome. Persistent left SVC, PA sling, and right tracheal bronchus were also detected by a chest computed tomography (CT) scan. He was diagnosed with paroxysmal supraventricular tachycardia (PSVT) associated with WPW syndrome, and underwent radiofrequency ablation. We reported the first case of situs solitus dextrocardia coexisting with persistent left SVC, PA sling and right tracheal bronchus presented with WPW and PSVT in a middle-aged adult. In patients with a cardiovascular anomaly, clinicians should consider thorough evaluation of possibly combined cardiovascular and airway malformations and cardiac dysrhythmia.
		                        		
		                        		
		                        		
		                        			Adult*
		                        			;
		                        		
		                        			Arrhythmias, Cardiac
		                        			;
		                        		
		                        			Bronchi
		                        			;
		                        		
		                        			Catheter Ablation
		                        			;
		                        		
		                        			Dextrocardia
		                        			;
		                        		
		                        			Electric Countershock
		                        			;
		                        		
		                        			Electrocardiography
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Artery
		                        			;
		                        		
		                        			Radiography, Thoracic
		                        			;
		                        		
		                        			Tachycardia
		                        			;
		                        		
		                        			Tachycardia, Supraventricular
		                        			;
		                        		
		                        			Thorax
		                        			;
		                        		
		                        			Vena Cava, Superior
		                        			;
		                        		
		                        			Wolff-Parkinson-White Syndrome*
		                        			
		                        		
		                        	
4.A Pulmonary Sequestered Segment with an Aberrant Pulmonary Arterial Supply: A Case of Unique Anomaly.
Minchul KIM ; Jeong Joo WOO ; Jin Kyung AN ; Yoon Young JUNG ; Yun Sun CHOI
Korean Journal of Radiology 2016;17(2):302-305
		                        		
		                        			
		                        			We presented a rare case of a 64-year-old man with a combined anomaly of the bronchus and pulmonary artery that was detected incidentally. Computed tomography showed a hyperlucent, aerated sequestered segment of the right lower lung with an independent ectopic bronchus, which had no connection to the other airway. The affected segment was supplied by its own aberrant pulmonary artery branch from the right pulmonary trunk. This anomaly cannot be classified with any of the previously reported anomalies.
		                        		
		                        		
		                        		
		                        			Bronchi/pathology
		                        			;
		                        		
		                        			Bronchopulmonary Sequestration/*radiography
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lung/*radiography
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Artery/*radiography
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
5.Main Pulmonary Artery Dilatation in Patients with Anthracofibrosis.
Journal of Korean Medical Science 2014;29(11):1577-1582
		                        		
		                        			
		                        			This study assessed main pulmonary artery diameter of patients with anthracofibrosis. Patients with anthracofibrosis and CT scans were evaluated after exclusion of patients with co-existing disease. We measured the diameter of the main pulmonary artery (PAD) and ascending aorta (AD) and calculated the pulmonary artery to aorta ratio (APR). The upper reference limit for comparison of PAD was 29 mm. Cut-off values for PAD and APR indicating pulmonary hypertension were 33 mm and 1. We correlated the CT parameters with echocardiographic results. Total 51 patients were included in the analysis. The mean PAD, AD, and APR were 33 mm, 38 mm, and 0.87 respectively. The PAD was larger than the upper reference limit, 29 mm (P<0.001). The PAD was >33 mm in 30 (65%) and the APR was >1 in 9 patients (18%). Of 21 patients with echocardiography, 11 (52%) were found to have pulmonary hypertension. There was no statistical difference in the diagnosis of pulmonary hypertension between echocardiography and CT (P=1.000). In conclusion, main pulmonary artery is dilated in patients with anthracofibrosis more than in the healthy population.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aged, 80 and over
		                        			;
		                        		
		                        			Aorta, Thoracic/*radiography
		                        			;
		                        		
		                        			Bronchi/pathology
		                        			;
		                        		
		                        			Bronchoscopy
		                        			;
		                        		
		                        			Dilatation
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fibrosis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypertension, Pulmonary/*diagnosis/ultrasonography
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Pulmonary Artery/*radiography
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
6.Clinics in diagnostic imaging (155). Incidental PDA with secondary pulmonary arterial hypertension.
May San MAK ; Ching Ching ONG ; Edgar Lik Wui TAY ; Lynette Li San TEO
Singapore medical journal 2014;55(9):462-quiz 467
		                        		
		                        			
		                        			We report the case of a 70-year-old man with an asymptomatic large patent ductus arteriosus (PDA) incidentally detected on triple-rule-out computed tomography (CT). CT clearly demonstrated a vascular structure connecting the descending thoracic aorta to the roof of the proximal left pulmonary artery, consistent with a PDA. Secondary pulmonary arterial hypertension was also evident on CT. The patient was eventually diagnosed with acute coronary syndrome and was successfully treated with coronary artery bypass graft surgery and concomitant patch closure of the PDA. This article aims to outline the imaging features of PDA and highlight the information provided by CT, which is crucial to treatment planning. The pathophysiology, clinical manifestations and closure options of PDA are also briefly discussed.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aorta, Thoracic
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Ductus Arteriosus, Patent
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Echocardiography
		                        			;
		                        		
		                        			Heart Diseases
		                        			;
		                        		
		                        			congenital
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypertension, Pulmonary
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Infant
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Obesity
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			Pulmonary Artery
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Radiography, Thoracic
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
7.Pulmonary Bone Cement Embolism: CT Angiographic Evaluation with Material Decomposition Using Gemstone Spectral Imaging.
Korean Journal of Radiology 2014;15(4):443-447
		                        		
		                        			
		                        			We report a case of pulmonary bone cement embolism in a female who presented with dyspnea following multiple sessions of vertebroplasty. She underwent spectral CT pulmonary angiography and the diagnosis was made based on enhanced visualization of radiopaque cement material in the pulmonary arteries and a corresponding decrease in the parenchymal iodine content. Here, we describe the CT angiography findings of bone cement embolism with special emphasis on the potential benefits of spectral imaging, providing additional information on the material composition.
		                        		
		                        		
		                        		
		                        			Angiography/methods
		                        			;
		                        		
		                        			Bone Cements/*adverse effects
		                        			;
		                        		
		                        			Dyspnea/etiology
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypotension/etiology
		                        			;
		                        		
		                        			Lung/radiography
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Artery/radiography
		                        			;
		                        		
		                        			Pulmonary Embolism/etiology/*radiography
		                        			;
		                        		
		                        			Tomography, X-Ray Computed/*methods
		                        			;
		                        		
		                        			*Vertebroplasty
		                        			
		                        		
		                        	
8.Assessment of Perfusion Pattern and Extent of Perfusion Defect on Dual-Energy CT Angiography: Correlations between the Causes of Pulmonary Hypertension and Vascular Parameters.
Eun Young KIM ; Joon Beom SEO ; Sang Young OH ; Choong Wook LEE ; Hye Jeon HWANG ; Sang Min LEE ; Young Kyung LEE
Korean Journal of Radiology 2014;15(2):286-294
		                        		
		                        			
		                        			OBJECTIVE: To assess perfusion patterns on a dual-energy pulmonary CT angiography (DECTA) of pulmonary hypertension (PHT) with variable causes and to assess whether the extent of perfusion defect can be used in the severity assessment of PHT. MATERIALS AND METHODS: Between March 2007 and February 2011, DECTA scans of 62 consecutive patients (24 men, 38 women; mean age, 58.5 +/- 17.3 [standard deviation] years; range, 19-87 years) with PHT were retrospectively included with following inclusion criteria; 1) absence of acute pulmonary thromboembolism, 2) maximal velocity of tricuspid regurgitation jet (TR Vmax) above 3 m/s on echocardiography performed within one week of the DECTA study. Perfusion patterns of iodine map were divided into normal (NL), diffuse heterogeneously decreased (DH), multifocal geographic and multiple peripheral wedging patterns. The extent of perfusion defects (PD), the diameter of main pulmonary artery (MPA) and the ratio of ascending aorta diameter/MPA (aortopulmonary ratio, APR) were measured. Pearson correlation analysis was performed between TR Vmax on echocardiography and CT imaging parameters. RESULTS: Common perfusion patterns of primary PHT were DH (n = 15) and NL (n = 12). The perfusion patterns of secondary PHT were variable. On the correlation analysis, in primary PHT, TR Vmax significantly correlated with PD, MPA and APR (r = 0.52, r = 0.40, r = -0.50, respectively, all p < 0.05). In secondary PHT, TR Vmax significantly correlated with PD and MPA (r = 0.38, r = 0.53, respectively, all p < 0.05). CONCLUSION: Different perfusion patterns are observed on DECTA of PHT according to the causes. PD and MPA are significantly correlated with the TR Vmax.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aged, 80 and over
		                        			;
		                        		
		                        			Aorta/physiopathology
		                        			;
		                        		
		                        			Aortography
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypertension, Pulmonary/physiopathology/*radiography
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Artery/physiopathology/*radiography
		                        			;
		                        		
		                        			Pulmonary Circulation/physiology
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Tomography, X-Ray Computed/*methods
		                        			;
		                        		
		                        			Tricuspid Valve Insufficiency/physiopathology/radiography
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
9.A Case of Extrinsic Compression of the Left Main Coronary Artery Secondary to Pulmonary Artery Dilatation.
Yoon Jung CHOI ; Ung KIM ; Jin Sung LEE ; Won Jong PARK ; Sang Hee LEE ; Jong Seon PARK ; Dong Gu SHIN ; Young Jo KIM
Journal of Korean Medical Science 2013;28(10):1543-1548
		                        		
		                        			
		                        			Extrinsic compression of the left main coronary artery (LMCA) secondary to pulmonary artery dilatation is a rare syndrome. Most cases of pulmonary artery hypertension but no atherosclerotic risk factors rarely undergo coronary angiography, and hence, diagnoses are seldom made and proper management is often delayed in these patients. We describe a patient that presented with pulmonary hypertension, clinical angina, and extrinsic compression of the LMCA by the pulmonary artery, who was treated successfully by percutaneous coronary intervention. Follow-up coronary angiography showed patent stent in the LMCA in the proximity of the dilated main pulmonary artery. This case reminds us that coronary angiography and percutaneous coronary intervention should be considered in pulmonary hypertension patients presenting with angina or left ventricular dysfunction.
		                        		
		                        		
		                        		
		                        			Angina Pectoris/etiology
		                        			;
		                        		
		                        			Angioplasty, Balloon, Coronary
		                        			;
		                        		
		                        			Coronary Angiography
		                        			;
		                        		
		                        			Coronary Stenosis/radiography/therapy
		                        			;
		                        		
		                        			Coronary Vessels/radiography/*ultrasonography
		                        			;
		                        		
		                        			Dilatation, Pathologic
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypertension, Pulmonary/etiology/radiography
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Artery/radiography/*ultrasonography
		                        			;
		                        		
		                        			Stents
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Ventricular Dysfunction, Left
		                        			
		                        		
		                        	
10.Diabetes mellitus and heart disease.
Anand AMBHORE ; Swee Guan TEO ; Kian Keong POH
Singapore medical journal 2013;54(7):370-quiz 376
		                        		
		                        			
		                        			Diabetes mellitus is responsible for diverse cardiovascular complications such as accelerated atherosclerosis, increased plaque burden and diffuse coronary lesions. It is also a major risk factor for myocardial infarction, stroke and peripheral vascular disease. Here, we present two cases. The first patient had subtle changes in the ECGs, with severe coronary artery disease requiring coronary artery bypass grafting, while the second had deep T wave inversion in the ECG and was found to have normal coronary arteries and nonischaemic cardiomyopathy. Although ECG failed to show the severity of the disease, it is invaluable as a simple, noninvasive test to aid in diagnosis. Our two cases stress the importance of a high index of suspicion and the low threshold for investigations in the diabetic population.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Biomarkers
		                        			;
		                        		
		                        			analysis
		                        			;
		                        		
		                        			Combined Modality Therapy
		                        			;
		                        		
		                        			Coronary Angiography
		                        			;
		                        		
		                        			Coronary Artery Bypass
		                        			;
		                        		
		                        			Coronary Stenosis
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Diabetes Complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			drug therapy
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Electrocardiography
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Edema
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Radiography, Thoracic
		                        			
		                        		
		                        	
            
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