2.Effect of tonsillotomy on the inflammation and immune function in children with chronic tonsillitis.
Yunwen WU ; Nannan ZHANG ; Lu WANG ; Qingfeng ZHANG ; Qing YUAN ; Xin WANG ; Huifen XIE ; Jiamu LV ; Jinen LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2023;37(4):297-301
Objective:To investigate the changes of inflammation and immune function in children with chronic tonsillitis after tonsillotomy. Methods:Prospectively collected 60 children with obstructive sleep apnea (OSA) diagnosed as chronic tonsillitis with adenoids and tonsillar hypertrophy from January to June 2021. Two groups were divided, the experimental group (n=30) underwent bilateral partial tonsillectomy + adenoidectomy by hypothermia plasma ablation, and the control group (n=30) underwent adenoidectomy by using the same hypothermia plasma ablation method. The number of tonsillitis attacks before surgery and within one year after surgery was recorded, and the serum immunoglobulin IgM, IgG, IgA, complement C3 and complement C4 levels before operation, one month and three months after operation were measured. Results:The number of tonsillitis attacks in the experimental group and the control group at one year after surgery was lower than that before surgery(P<0.05); The number of inflammatory attacks in the experimental group was (0.50±0.63) times/year, which was lower than that of (1.33±0.80) times/year in the control group. There was no significant difference in the five immunization results of the two groups at one month and three months after operation compared with before operation, and there was also no significant difference between the experimental and the control groups. Conclusion:Partial tonsillectomy can be applied to children with chronic tonsillitis, which can effectively reduce the number of tonsillitis attacks and has no effect on the immune function of children.
Child
;
Humans
;
Tonsillectomy/methods*
;
Hypothermia
;
Tonsillitis/surgery*
;
Adenoidectomy
;
Palatine Tonsil/surgery*
;
Inflammation
;
Chronic Disease
;
Immunity
3.Immune function alteration in children after tonsillectomy and(or) adenoidectomy.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2016;30(5):418-423
Tonsillectomy and(or) adenoidectomy are effective procedures for children with chronic tonsillitis, diseases associated with the tonsil and other adenotonsillar diseases, and obstructive sleep apnea-hypopnea syndrome. Since the tonsil and adenoid gland play a dual role in fluid and cell immunity, whether adenotonsillectomy results in the abnormal immune function in children after the surgery has always been the focus of attention. This review focuses on the alterations and impacts on immunity in children after tonsillectomy and/or adenoidectomy. Recent studies confirmed that in short term the immune index may be slightly reduced after the tonsil and adenoid resection in children, however, the decline has no clinical significance because the remaining mucosa-associated lymphoid tissue can compensate for removal of the tonsils and adenoids. Over time, the immune index tends to be normal. The children's postoperative short-term decline in the immune index will gradually recover to the preoperative level or there is no significant difference compared with that in normal children. Therefore, long-term immune function did not decline after tonsil and adenoid resection in children.
Adenoidectomy
;
Adenoids
;
surgery
;
Child
;
Humans
;
Immunity, Cellular
;
Palatine Tonsil
;
surgery
;
Postoperative Period
;
Tonsillectomy
;
Tonsillitis
;
surgery
4.Effects of different surgical procedures on immunity of children with obstructive sleep apnea hypopnea syndrome.
Juanjuan ZHOU ; Yan WANG ; Yanzhong LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2016;30(5):396-398
OBJECTIVE:
To explore the effects of pure adenoidectomy,adenoidectomy with partial tonsillectomy,and adenoidectomy with total tonsillectomy on humoral and cellular immunity of children with OSAHS.
METHOD:
The children with OSAHS diagnosed by polysomnography were divided into pure adenoidectomy group(group A),adenoidectomy with partial tonsillectomy group(group B), and adenoidectomy with total tonsillectomy(group C), and there were 50 cases in each group. The serum IgG, IgA, IgM level and peripheral blood T cell subgroup per-centage were detected at 6 months preoperatively and postoperatively. Tonsil grading and polysomnography wereconducted, recording symptoms improvement situation at postoperative 6 months.
RESULT:
There was no statisticallysignificant difference compared with preoperative(P>0. 05) in humoral immunity and cellular immunity index ofpostoperative 6 months. There was no significani difference(P>C. 05) in curative effect among three groups in the 6th month post-operatively.
CONCLUSION
All of these three surgical procedures had no obvious effect on humoral orcellular immune function in children, and could effectively treat children OSAHS.
Adenoidectomy
;
Antibodies
;
blood
;
Child
;
Humans
;
Immunity, Cellular
;
Immunity, Humoral
;
Palatine Tonsil
;
pathology
;
Polysomnography
;
Postoperative Period
;
Sleep Apnea, Obstructive
;
immunology
;
surgery
;
T-Lymphocyte Subsets
;
cytology
;
Tonsillectomy
5.Giant tonsillolith in a child.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(2):180-181
We describe a case of a 7-year-old child with Down syndrome who presented with loud snoring and cessation of breath during sleep and was found to have a large calculus (20 mm X 12 mm X 12 mm) in her left tonsil by CT scan for which tonsillectomy with adenoidectomy were done. This is one of the youngest reported cases in the literature.
Adenoidectomy
;
Calculi
;
complications
;
surgery
;
Child
;
Female
;
Humans
;
Lymphatic Diseases
;
Palatine Tonsil
;
pathology
;
Pharyngeal Diseases
;
Sleep
;
Snoring
;
Tomography, X-Ray Computed
;
Tonsillectomy
6.Analysis of related factors of tonsil postoperative pain.
Xin ZHANG ; Lanlan WAN ; Junying WANG ; Yu XU ; Peizhong LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(2):137-139
OBJECTIVE:
To explore the related factors of tonsil postoperative pain.
METHOD:
After founding databank a statistic analysis was performed on 90 cases with tonsillectomy who admitted in our hospital. Chi-square test were used to investigate the related factors for postoperative pain in those patients.
RESULT:
After Chi-square test, the important effect factors in the postoperative pain were gender, age, surgical methods, preemptive analgesia, physical analgesia and preoperative anxiety level.
CONCLUSION
The pain after tonsillectomy is influenced by not only surgery itself, but also by preemptive analgesia, preoperative anxiety level and so on.
Humans
;
Pain Measurement
;
Pain, Postoperative
;
Palatine Tonsil
;
surgery
;
Tonsillectomy
7.Extra-tonsillar approach to the styloid process.
Qingquan ZHANG ; Shaohong JIANG ; Xiumei CHEN ; Hua ZHANG ; Zhonglu LIU ; Li WANG ; Xin YANG ; Xiaoyong WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2014;49(5):412-413
Adult
;
Female
;
Humans
;
Male
;
Middle Aged
;
Palatine Tonsil
;
surgery
;
Temporal Bone
;
abnormalities
;
surgery
8.Radiofrequency coblation for treatment of abnormal sensation of throat induced by the hypertrophy of lingual tonsil.
Qingfeng ZHANG ; Cuiping SHE ; Hui WANG ; Yue ZHANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(3):185-187
OBJECTIVE:
The aim of the present study was to evaluate the effects of radiofrequency coblation surgery for treatment of abnormal sensation of throat induced by the hypertrophy of lingual tonsil.
METHOD:
Three hundred and seven patients affected by abnormal sensation of throat induced by the hypertrophy of lingual tonsil were enrolled. Radiofrequency coblation was performed on all patients under nasal endoscopy. A comprehensive statistics were obtained from all the participants regarding the recovery of wound surface, postoperative pain, intra and postoperative bleeding and the effects of the procedure.
RESULT:
The VAS score of abnormal sensation of throat was reduced from (9.3 +/- 0.6) to (3.7 +/- 2.4) (P<0.05) after the operation. 84.4% of the abnormal sensation dis appeared, no recurrence within six month; 6.8% of the abnormal sensation largely reduced within six month; 4.6% of the abnormal sensation reduced within six month. There was no significant postoperative pain. 3.6% (11/307) of patients experienced postoperative hemorrhage. The follow-up period ranged from 6 to 36 months, there was no recurrence.
CONCLUSION
Radiofrequency coblation is a useful surgical technique, as effective as,or even superior to,other surgical techniques when dealing with patients suffering from abnormal sensation of throat induced by the hypertrophy of lingual tonsil with potentially fewer adverse effects and subsequently improved quality of life for patients.
Adult
;
Catheter Ablation
;
methods
;
Female
;
Foreign-Body Reaction
;
etiology
;
surgery
;
Humans
;
Hypertrophy
;
Male
;
Middle Aged
;
Palatine Tonsil
;
pathology
;
Tongue
;
pathology
;
Young Adult
9.Preliminary study on treatment of lingual tonsil hypertrophy by endoscopic assisted coblation.
Qingxiang ZHANG ; Weiguo ZHOU ; Guangfei LI ; Huiying HU ; Qiuping WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(14):787-789
OBJECTIVE:
To investigate the feasibility and safety of lingual tonsil excision by endoscopic assisted coblation.
METHOD:
Twenty seven cases with lingual tonsil hypertrophy were recruited in this study. Preoperative fibrolaryngoscope and CT and (or) MRI examination of the base of the tongue, lingual tonsil was removed by 70 degrees nasal endoscopy-assisted plasma radiofrequency after nasotracheal intubation. The tongue wound healing and post-operative bleeding were observed after operation, the advantages of the endoscopic-assisted plasma radiofrequency on lingual tonsil removal were analyzed, and its feasibility and safety were summarized.
RESULT:
During the surgery the base of the tongue and epiglottis had satisfaction exposure in the same operative field. No complications happened in the surgery and endotracheal tube was plucked safely after operation. There was no primary bleeding, and the number of secondary bleeding were 4 cases, accounting for 14.81% (4/27), respectively occurred on the sixth, seventh, tenth and twelfth day with the amount of bleeding of 30-70 ml. The bleeding were cured after conservative treatment or re-application applicating of radiofrequency; 27 patients had no taste disturbance, and they were followed up for 6-30 months without recurrence.
CONCLUSION
Lingual tonsil excision by nasal endoscopic-assisted coblation has enough exposure, complete resection and low recurrence rate. Stopping bleeding should be attentioned to prevent postoperative bleeding.
Adult
;
Catheter Ablation
;
methods
;
Endoscopy
;
Female
;
Humans
;
Hypertrophy
;
surgery
;
Male
;
Middle Aged
;
Palatine Tonsil
;
pathology
;
Pharyngeal Diseases
;
Tongue
;
pathology
10.Postoperative changes of immunity in children undergoing adenoidectomy with tonsil ablation or with partial tonsillectomy.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2011;25(21):990-992
OBJECTIVE:
To investigate the changes of humoral and cellular immune responses in children with OSAHS after adenoidectomy with tonsil ablation or partial tonsillectomy by a plasma-mediated radiofrequency-based device.
METHOD:
Seventy children with OSAHS were enrolled in the study. According to the size of tonsils, they were divided into two groups: the adenoidectomy with tonsil ablation group and the adenoidectomy with partial tonsillectomy group. 4 ml of peripheral venous blood was drawn before and 1 month, 3 months after operation. Serum IgG, IgA, IgM levels and peripheral blood T lymphocyte subsets were measured.
RESULT:
In the adenoidectomy with tonsil ablation group, the level of CD3+ and CD4+ /CD8+ ration were slightly increased, while the levels of CD4+ and CD8+ were slightly reduced at 1 month after operation as compared to preoperative period. However, in the adenoidectomy with partial tonsillectomy group, the levels of CD8+ at 1 month after operation were slightly increased compared with that in preoperative examination, while the CD3+, CD4+ level and the CD4+/CD8+ ratio were slightly reduced during the same period. In addition, the levels of serum immunoglobulins showed no significant difference between the two groups, and returned to the preoperative levels at 3 months after operation in both groups (P > 0.05).
CONCLUSION
The results of the present study indicate that the humoral and cellular immunity is not affected in children with OSAHS who undergo adenoidectomy with tonsil ablation or partial tonsillectomy using plasma-mediated radiofrequency ablation. The patients' immune functions can return to normal levels at 3 months after the surgery.
Adenoidectomy
;
Child
;
Child, Preschool
;
Cryosurgery
;
methods
;
Female
;
Humans
;
Immunity, Cellular
;
Immunity, Humoral
;
Immunoglobulin A
;
blood
;
Immunoglobulin G
;
blood
;
Immunoglobulin M
;
blood
;
Male
;
Palatine Tonsil
;
surgery
;
Postoperative Period
;
Sleep Apnea, Obstructive
;
immunology
;
surgery
;
T-Lymphocyte Subsets
;
immunology
;
Tonsillectomy
;
Treatment Outcome

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