1.Treatment of miniere’s disease (icd-10 h.81) using traditional medicine and therapeutic interventions: Case report
Undarmaa B ; Tserendulam G ; Oyun-Erdene U ; Oyunnyam Ch ; Nasankhishig D ; Khaliun E ; Tsegmed G ; Oyunbileg Yu ; Enkhtuya V
Mongolian Journal of Health Sciences 2025;87(3):72-74
		                        		
		                        			Background:
		                        			Meniere's disease is a condition caused by disturbances in the
auditory and vestibular systems. It is characterized by symptoms such as dizziness,
nausea, vomiting, and tinnitus. In the United States, the prevalence of
Meniere's disease has been found to be 84 cases per 100,000 women and
56 cases per 100,000 men. Regionally, it is more common in less populated
areas, and research has confirmed that the prevalence increases with higher
household income.
		                        		
		                        			Aim:
		                        			To evaluate the effectiveness of traditional medicine treatments and therapies
for Meniere's disease.
		                        		
		                        			Results:
		                        			The patient is a 43-year-old male, with symptoms of dizziness, vomiting,
and tinnitus. Since 2023, he has sought care at the Central Hospital of
Mongolian Medicine, where he received traditional medicine treatments including
herbal therapy and other traditional therapies on three occasions. As a
result, the frequency of dizziness has decreased and other clinical symptoms
have improved.
		                        		
		                        			Conclusion
		                        			Traditional medicine treatments have been shown to be effective
in managing Meniere's disease by extending the interval between relapses,
improving quality of life, and significantly reducing clinical symptoms.
		                        		
		                        		
		                        		
		                        	
2.Result of a study on some effects of (Allium polyrhizum Turcz. ex Regel) preparation on a type 2 diabetic model
Oyun-Erdene R ; Gerelt Borjikhan ; Munkhtsetseg J
Mongolian Journal of Health Sciences 2025;85(1):130-135
		                        		
		                        			Background:
		                        			 Diabetes mellitus (DM) is a complex metabolic disorder involving many organs and can devastate the 
lives of affected individuals. It is characterized by chronic high blood glucose that could lead to morbidity and mortality. 
The number of people suffering from diabetes worldwide is increasing at an alarming rate. It is predicted that about 366 
million people are likely to be diabetic by the year 2030. Since all of the previous studies have focused on the therapeutic 
role of (Allium polyrhizum Turcz. ex Regel) preparations in diabetes mellitus, we investigated the preventive effect of oral 
administration of (Allium polyrhizum Turcz. ex Regel) extract on the changes of biochemical factors and histopathology 
alterations in hepatic tissue caused by diabetes. Therefore, this study aimed to investigate the effect of water extract (Allium polyrhizum Turcz. ex Regel) on the metabolism of rats with diabetes induced by a high-fat diet and streptozotocin. 
		                        		
		                        			Aim:
		                        			 To investigate the antidiabetic properties of aqueous extract of (Allium polyrhizum Turcz. ex Regel) and its beneficial 
effect on hematological parameters in streptozotocin-induced diabetic rats.
		                        		
		                        			 Materials and Methods:
		                        			Experimental was performed at the Institute of Mongolian Medicine and Chemistry, Inner 
Mongolia University. Male Wistar rats weighing (180 g) were obtained from The Animal Experimental Unit of Mongolia 
Medicine and Chemistry Research Center, Inner Mongolia University. 
The rats were housed in well-aerated individual cages in an animal room and maintained in a temperature-controlled 
room (24±25°C) with a 12 h light/12 h dark cycle, 50-60 % humidity. They were fed with normal commercial chow and 
water ad libitum. Throughout the experiments, animals were processed according to the suggested international ethical 
guidelines for the care of laboratory animals, and all experimental procedures were approved by the Animal Care and Use 
Committee of Inner Mongolia University.
 After 4 weeks, the rats were fasted for 8 h before blood sampling, water was not restricted. Blood samples were collected 
from the orbital venous plexus.
		                        		
		                        			 Results:
		                        			 The blood glucose level was significantly increased in model group 24.14±2.28 mmol/L, to Control group 
5.31±0.49 mmol/L. Oral administration of Allium polyrhizum Turcz.ex Regel treated group 10.5±4.05 mmol/L, Metformin treated group 9.05±2.71 mmol/L resulted in significantly decreased blood glucose levels less model group. 
		                        		
		                        			Conclusion
		                        			 The results of this study indicate that Allium polyrhizum Turcz.ex Regel possesses hypoglycemic, hypolipidemic, and antioxidant effects in STZ-induced diabetic rats and therapy of diabetes and its complications especially when 
used for a longer period.
		                        		
		                        		
		                        		
		                        	
3.Comparative study results of serum vitamin D status in trained athletes in Mongolia
Oyu-Erdene Kh ; Bulgan M ; Oyun-Erdene R
Mongolian Medical Sciences 2024;207(1):8-14
		                        		
		                        			Introduction:
		                        			The last decade has seen a dramatic increase in general interest in and research into vitamin D, with 
many athletes now taking vitamin D supplements as part of their everyday dietary regimen. The most 
recognized role of vitamin D is its regulation of calcium homeostasis; there is a strong relationship 
between vitamin D and bone health in non-athletic individuals. Vitamin D is responsible for regulation 
of calcium and phosphate metabolism and maintaining a healthy mineralized skeleton. It is also known 
as an immunomodulatory hormone. Experimental studies have shown that 1,25-dihydroxyvitamin D, 
the active form of vitamin D, exerts immunologic activities on multiple components of the innate and 
adaptive immune system as well as endothelial membrane stability. Studying the level of vitamin D in 
athletes in relation to age group, body mass index, and type of sport is important for reducing the risk of 
injury and infection in athletes and improving performance and success in sports.
		                        		
		                        			Goal:
		                        			To determine the 25-hydroxyvitamin D [25(OH)D] levels in the plasma of the trained athletes and their 
vitamin D status to compare of their sports type.
		                        		
		                        			Materials and Methods:
		                        			
Sample size
Using a cross-sectional design, a total of 71 athletes aged 20-43 from the sports medicine research 
center and the national team was selected by sampling.
Method of the Laboratory analyses
The body mass index and blood plasma level of 25 hydroxy vitamin D of the athletes participating in the 
study were compared by sports type and analyzed using descriptive statistics. Comparison of survey 
data was performed using Pearson’s correlation method.
		                        		
		                        			Results:
		                        			In the study, 71 athletes of the Mongolian national team participated in 5 types of sports. Descriptive 
analysis was performed on the general parameters of the athletes, body mass index, type of sport, level 
of vitamin D in the blood, etc.
An avarege level of vitamin D of the athletes who participated in our study were 22.27±12.9 ng/ml, in the age group of 20-29 years, and compared to the body mass index, it was the highest level in the athletes of normal weight. 
		                        		
		                        			Conclusions
		                        			
1. The level of vitamin D of the athletes who participated in our study was the highest in the age group 
of 20-29 years, 22.27±12.9 ng/ml, and compared to the body mass index, it was the highest level 
in the athletes of normal weight.
When studying the level of vitamin D of the participants in comparison with the type of sport, the 
freestyle wrestlers had a higher level of 34.75±15.13 ng/ml, while the judo wrestlers had a lower 
level of 12.69±5.17 ng/ml.
		                        		
		                        		
		                        		
		                        	
4.Studying the relationship of air pollutants and pulmonary disease in Yesunbulag sum, population of Gobi-Altai province
Myagmardorj Ch ; Oyun-Erdene O ; Nyandag Ch ; Bataa Ch ; Suvd B
Mongolian Medical Sciences 2024;207(1):30-36
		                        		
		                        			Introduction:
		                        			In 2020, the prevalence of respiratory system diseases in the population of Gobi-Altai province is 
1339.5 cases per 10,000 population, which is 4% (52) more than the average of the provinces and 
20% (223.8) more than the national average. In 2021, the number of deaths due to respiratory system 
diseases was 2.9 per 10,000 population, increasing by 1.1 from 2020 (1.8). Pneumonia-related deaths 
account for 60.7% of all respiratory system-related deaths. As of 2022, there are 7,281 simple stoves, 
248 low-pressure and steam boilers, and 18,207 automobiles in the Gobi-Altai province as sources of 
air pollution. 63.1% of the total coal is consumed by water heating boilers with a capacity of more than 
101 kW, 20.5% by households, and 16.4% by small and medium enterprises.
		                        		
		                        			Goal:
		                        			Determining the relationship between the incidence of pneumonia in the population of Gobi-Altai 
province and the common air pollutants.
		                        		
		                        			Material and Method:
		                        			According to the rotation research model, the common external air pollutants SO₂, NO₂, PM₁₀, 
climate parameters, temperature, pressure, humidity, and population pneumonia measurements 
and registration data of Altai Sum, Gobi-Altai Province in 2020-2021 were analyzed using SPSS-24 
software. statistical processing was calculated for non-parametric parameters.
		                        		
		                        			Result:
		                        			 The annual average value of sulfur dioxide (SO₂ ) measured in 20 minutes in Gobi-Altai province is 
25.2 ± 13.7 μg/m³, the annual average value of nitrogen dioxide (NO₂) measured in 20 minutes is 
36.329±29 μg/m³, and the annual average concentration of PM₁₀ particles is 35.2 ± 28,264 μg/m³, 
which is the standard level of MNS4585:2016. But the 20-minute average concentration of SO₂
 (r=0.81, p=0.005), the average concentration of NO₂  (r=0.089, p=0.008), and the average concentration of PM₁₀  (r=0.089, p=0.002) is directly related to the incidence of pneumonia. It is also inversely correlated with air temperature (r=-142, p=0,000).
		                        		
		                        			Conclusion
		                        			Common outdoor air pollutants in Yesunbulag sum, Gobi-Altai Province are related to 
pneumonia in children aged 0-5 years.
		                        		
		                        		
		                        		
		                        	
5.Results of the study on pathogens in vaginal smear tests
Mungunshagai A ; Oyun-Erdene R ; Munkhzul N
Mongolian Medical Sciences 2024;208(2):3-7
		                        		
		                        			Introduction:
		                        			 Although bacterial vaginosis prevalence varies across countries and populations, recent systematic 
reviews and meta-analyses indicate that 23–29% of women of reproductive age are infected. Each 
year, 21.2 million (22.9%) women between the ages of 14 and 49 in the United States develop bacterial 
vaginosis. Microenvironments are interconnected with the endocrine, immune, and other organ 
systems and dependent upon external and internal environmental influences. In women between the 
ages of 15 and 44, bacterial vaginosis is the most common vaginal disorder, according to the Centers 
for Disease Control and Prevention. 
In our nation, 93.4% of women who are of reproductive age have vaginalis; the percentage of cases 
with Gardnerella vaginalis alone is 22.6%, and 53.1% have it in combination with other anaerobic 
bacteria, which is a significant percentage. Our research is based on the lack of information about the 
vaginal environment of Mongolian women and factors influencing changes in the microenvironment. 
Our research is based on the lack of information about the vaginal environment of Mongolian women 
and factors influencing changes in the microenvironment. 
		                        		
		                        			Goal:
		                        			The objective is to study how age relates to the development of bacterial and fungal vaginitis through 
the analysis of vaginal swabs. 
		                        		
		                        			Materials and Methods:
		                        			For our study, we selected 100 women aged 20-59 through targeted sampling from clients who 
underwent vaginal smear tests at “Yu Bi Lab” laboratory and “Tsetsuu” diagnostic center in Ulaanbaatar 
in 2023. Vaginal smear analysis was conducted using Nugent’s criteria and Gram staining. Statistical 
analysis was performed by comparing pathogens among the participants based on age using 
Pearson’s correlation method. We obtained permission to conduct research. 
Through the Etugen University Biomedical Ethics Comittee convention held on march 11,2024
		                        		
		                        			Results:
		                        			The study divided 100 women into four age groups to examine the vaginal environment with their age 
and the factors influencing it. The research aimed to understand how bacterial vaginitis and fungal 
vaginitis evolve during reproductive age and menopause. Among the age groups, women aged 20-29 
had an average of 5.59±3.35 epithelial cells (n=32), those aged 30-39 had 6.10±3.29 (n=37), women 
aged 40-49 had 6.70±3.90 (n=17), and women aged 50-59 had the highest number of epithelial cells 
at 9.42±8.19 (n=14), representing 34% of the group.
		                        		
		                        			Conclusion
		                        			
1. Women of reproductive and menopausal age experience changes in the vaginal environment due to 
various factors. This includes a decrease in the ratio of normal microorganisms and lactobacilli, an increase in the number of conditional pathogens, and the development of an alkaline environment 
in the vagina.
2. Bacterial vaginitis predominantly affects younger women, with symptoms often being subtle. In 
contrast, fungal vaginitis is more common among menopausal women. Lower estrogen levels in 
women in this age group cause lactobacilli to break down glycogen less efficiently into lactic acid, 
even though the number of lactobacilli is still normal. This research implies that suppositories and 
estrogen pills may help treat these problems for women between the ages of 40 and 59.
		                        		
		                        		
		                        		
		                        	
6.Results of thyroid hormone levels in women
Bolor B ; Bat-Erdene D ; Oyun-Erdene R
Mongolian Medical Sciences 2024;208(2):8-12
		                        		
		                        			Introduction:
		                        			The average age of the population varies in every country of the world, which depends on the changes 
that occur in the body during aging and many external and internal factors that affect it. Thyroid 
hormones play an important role in ensuring and maintaining normal metabolic function throughout 
life. Our country is located in a mountainous region of the mainland, the amount of iodine in drinking 
water is low, and the amount of iodine taken from food is low, which creates the risk of iodine deficiency 
disorders. Therefore, we aimed to study how the thyroid function changes with age in Mongolian 
people.
		                        		
		                        			Goal:
		                        			A comparative study of thyroid hormone secretion levels in adult women.
		                        		
		                        			Material and Method:
		                        			In our study, 83 women over the age of 20 were selected based on the “Yu Bi Lab” diagnostic center. 
Triiodothyronine (T3), thyroxine (T4), and thyrotropin (TSH) of the women participating in the study 
were determined using the FHU method using the Magiwel ELISA diagnostic kit manufactured by 
United Biotech. 
		                        		
		                        			Results:
		                        			81 women over 20 years of age participated in our study, the average age was 44.45±14.17, and the 
participants were divided into 5 groups with 10 age intervals. 20-29 years 18% (n=15) average age 
24.6±2.64, 30-39 years 22% (n=18) average age 33.6± 3.12, 40-49 years 16% (n=13) average age 
45.15±1.67, 50-59 years 25% (n=20) average age 54.15±2.99, 60-69 years 19% (n=15) average age 
63.73± 3.05, were.
		                        		
		                        			Conclusion
		                        			
1. When comparing T3 and T4 hormones by age group, T3 hormone is higher in the 30-39 age group 
at 5.05 ng/ml. The T4 hormone gradually decreases with age.
 
2. Thyroiodin hormone increased with age. The relationship between the age of the participants 
and TSH hormone was directly related to statistical age when calculated by Pearson’s correlation 
coefficient (p=0.01).
		                        		
		                        		
		                        		
		                        	
7. A study to determine actual daily consumption of drinking and residential water for households in Ulaanbaatar
Zolzaya D ; Suvd B ; Amgalan G ; Tsegmed S ; Bolor B ; Soyombo G ; Oyun-Erdene O ; Altangerel B ; Oyunchimeg D ; Enkhjargal A ; Bolormaa I ; Tsogtbaatar B
Mongolian Medical Sciences 2024;208(2):39-47
		                        		
		                        			Introduction :
		                        			Water is a vital resource for human existence and is essential for daily food processing, preparation, 
washing, hygiene, and sanitation. Furthermore, providing the population with safe drinking water is one 
of the pressing problems of the world and some regions. 
In recent years, population density and the scale of commercial and industrial activities, as well as clean 
and dirty water consumption were increased in the capital city. As a result of these, ground and surface 
water resources are becoming scarce and polluted. 
Therefore, assessment of daily drinking and residential water consumption of Ulaanbaatar should be 
determined to use drinking water properly in daily life and water loss. This study assessed the actual 
amount of households’ daily water consumption.
		                        		
		                        			Goal:
		                        			The purpose of this study is to determine the daily consumption of drinking water for households in ger 
areas and apartments in Ulaanbaatar.
		                        		
		                        			Materials and Method:
		                        			This study covers 30 households in ger areas and 15 apartment households, in Ulaanbaatar. 
Household members performed 6-10 types of measurements every day, within 7 days. As a result of 
these measurements, actual consumption of water quantity used for drinking and household purposes 
was calculated. Statistical analysis was done by SPSS Version 21 to calculate the true probability of 
difference between parameters.
		                        		
		                        			Result:
		                        			67.9% of the households in the ger areas were 4-5 family members. The average daily household 
consumption of drinking and domestic water were 68.3 ± 3.57 L (95% 61.3-75.3), the minimum 
consumption was 12 L, and the maximum was 227 L. Average of the household water consumption 
water was 97.6-108.9 liters during the weekends, and water consumption was statistically higher than 
weekdays (p=0.001; p=0.01).
 The water consumption of residential households with 3 family members accounted for the majority 
(30.8%) in this study. The average daily consumption of drinking and domestic water was 297.67±19.7 
liters. There was no statistically significant difference (p=0.96) in week. The average daily water 
consumption including drinking and residential was 270.3-335.97 L.
 The total daily drinking and residential water consumption per person was 15.57 L for households in ger areas and 90 L for apartment households. Calculating the daily water consumption of households in ger areas, 60.3% of it is used for laundry, washing dishes, food preparation, washing face and hands, and clothes, 31% for drinking, and 8.7% for outdoor water use. While apartment households, approximately 94.1%, were used for household and 5.9% for drinking purposes.
		                        		
		                        			Research ethics approval :
		                        			This study was discussed at the meeting of the Academic Council of the National Center for Public 
Health. In addition, this study was carried out according to the methods and methods discussed and 
approved at the meeting of the Medical Ethics Control Committee of the Ministry of Health (Resolution 
No. 08).
		                        		
		                        			Conclusion 
		                        			The total daily consumption of drinking and residential water per person were 15.57 litres for the 
households in the ger areas and 90 litres for the apartment households. It implies that it does not exceed 
the WHO recommendations
		                        		
		                        		
		                        		
		                        	
8.Assessment of progress examination
Mongolian Pharmacy and Pharmacology 2023;22(1):56-61
		                        		
		                        			Introduction:
		                        			The World Association of Medical Education organizes medical education and postgraduate student training worldwide.
One of the indicators of the quality assurance of higher medical education is the need for schools providing medical education to have a unified evaluation method and to assess the level of knowledge, skills, and attitudes acquired by students. In order to objectively evaluate the student to improve the assessment of clinical skills, it is necessary to regularly evaluate the examination parameters. Thus, the evaluation of the clinical skills of the schools providing medical education needs to be accurate and objective, and it is necessary to develop a general evaluation model, so this study was selected for conducting.
		                        		
		                        			Goal:
		                        			Analyzing tasks in advanced skills tests
		                        		
		                        			Material and Methods:
		                        			In our research work, we used the numerical data of the students’ achievement presented to him by a total of n=113 clinical case assignments of the 6 stations of the 5th year advanced skills test of the School of Health of Etugen University.
		                        		
		                        			Research results:
		                        			Examining the reliability of the progress skills test with examinee performance at each of the 6 stations, reliability at the anamnesis station (KR=0.91) was a maximum score of 100, a minimum score of 16.5, and reliability at the actual examination station (KR=0.90) was a maximum score of 100, minimum score 40, reliability on diagnosis station (KR=0.93) maximum inter-examiner score 100, minimum score 61, reliability on manual action station (KR=0.88) maximum inter-examiner score 100, minimum score 64, reliability on treatment station (KR=0.85) The maximum score of the examinees was 100, the minimum score was 23, and the reliability of the counseling center (KR=0.90) was the maximum score of the examinees was 100, and the minimum score was 45.
		                        		
		                        			Conclusion
		                        			1. The reliability of the test is at a sufficient level without statistically significant differences in 6
stations.
2. The clinical case of each examination station differs in the degree of difficulty of the task: 30 percent (n=95) of the 20 tasks at the treatment station are very difficult, 33.0 percent (n=104) are difficult, 22.7 percent (n=87) are ideal, and 8.9 percent are ideal. (n=28) clinical cases with mild symptoms were evaluated. It is possible to set a threshold of 70 percent for passing the Advanced Skills Test.
		                        		
		                        		
		                        		
		                        	
9.Allium polyrhizum Turcz.ex Regel results of aboveground research
Oyun-Erdene R ; Gereltu Borjihan
Mongolian Medical Sciences 2023;203(1):39-43
		                        		
		                        			Introduction:
		                        			Human beings have been using raw materials of plant and animal origin for the treatment of various diseases. Nowadays, in developed and developing countries, plant raw materials are widely used in traditional medicine, health care, and food supplements, and they are used as raw materials in pharmaceutical production, making up a large part of the world pharmaceutical market. Therefore, research activities are intensively carried out to determine the chemical composition and mineral content of plant-derived raw materials and explain the mechanism of action.
		                        		
		                        			Goal:
		                        			Allium polyrhizum Turcz.ex Regel determination of chemical compounds macro and micro elements and amino acids
		                        		
		                        			Material and Methods:
		                        			Allium polyrhizum Turcz.ex Regel was collected and prepared from Huvut shar Khoshun, Shili River Province, Institute of Mongolia medicine chemistry, Inner Mongolia university, Inner Mongolia Key Laboratory Medicine Chemistry. then it was made into a type with 0.075 mm particle size by a grinding machine. 
		                        		
		                        			Result:
		                        			Dete-rmining the elemental composition of plant raw materials is important for determining the therapeutic value and safety of the plant. Some elements in Allium polyrhizum Turcz.ex Regel were determined by X-ray fluorescence method.
		                        		
		                        			Conclusions
		                        			1. In this study, the content of 7 elements in the above-ground part of Allium polyrhizum Turcz was determined using the XRF analysis method. Of the macro and micro elements such as Ca, K, Mn, Fe, Na, Zn, and Mg, which are essential for the human body, potassium (K) 49.7 mg/kg, calcium (Ca) 45.7 mg/kg, and sodium (Na) 31.0 mg/kg are the most had a high concentration.
2. Among various amino acids involved in protein synthesis, glutamic acid 1.89 mg, aspartic acid 1.48 mg, and alanine 1.00 mg were identified.
		                        		
		                        		
		                        		
		                        	
10.Review on phytochemical composition and biological activity of Saxifraga L.
Mongolian Pharmacy and Pharmacology 2023;23(2):12-19
		                        		
		                        			Abstract
		                        			 The genus Saxifraga, one of the largest genera of the Saxifragaceae family, comprises
465 species and is distributed widely in mountainous and rocky regions, with 12 species being
found in Mongolia. In Asian folk medicine, numerous wild-collected Saxifraga species are used
to treat different disorders, including cancer, headache, hemorrhoids, influenza, liver diseases,
neuralgia, phthisis bulbi. and tympanitis. Moreover, the aerial parts of S. spinulosa are used in
Russia and the Tibetan plateau to treat conjunctivitis, gynecopathy, and diseases of the larynx.
Since 1970's, chemical constituents of Saxifraga species started to be studied. Currently, about
150 secondary metabolites from more than 23 species were isolated and their structure elucidated, including flavonoids, phenolic compounds, triterpenes and steroids, and other class of copmpounds. Extracts and isolated pure compounds from Saxifraga species showed antioxidants and
hepaprotective, anticancer and inhibitory activities against Babesia and Theileria parasites.
		                        		
		                        		
		                        		
		                        	
            
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