BACKGROUND AND OBJECTIVES: A considerable proportion of sinus diseases is associated with a unilateral lesion. Unilateral paranasal pathological lesions require precise preoperative diagnosis and histopathological assessment. This study aimed to analyze the changes in etiologies and clinical characteristics of operated unilateral sinus diseases between 2005 and 2015. SUBJECTS AND METHODS: Two hundred eighteen operated cases with unilateral sinus disease in 2005 and 2015 were reviewed to retrospectively analyze the etiologies and clinical characteristics. RESULTS: In 2015 compared with 2005, the proportion of unilateral sinus disease and patient age were increased. The proportions of patients with allergic rhinitis and hypertension were significantly increased in 2015. The leading cause of unilateral sinus lesions was nasal polyp, followed by fungus, tumor, mucocele, anatomical variation, odontogenic sinusitis, and foreign body. This ranking did not change between 2005 and 2015. The number of patients with fungal sinusitis was significantly increased in 2015. The direction of nasal septal deviation had no statistically significant relation with unilateral sinus disease. CONCLUSION: This comparison study of unilateral sinus disease between 2005 and 2015 showed that the proportion of fungal sinusitis, patient age, and patients with underlying disease were increased.
Diagnosis ; Foreign Bodies ; Fungi ; Humans ; Hypertension ; Mucocele ; Nasal Polyps ; Nasal Surgical Procedures ; Paranasal Sinus Diseases ; Retrospective Studies ; Rhinitis, Allergic ; Sinusitis

Frontal sinus outflow tract (FSOT) injury may occur in cases of frontal sinus fractures and nasoethmoid orbital fractures. Since the FSOT is lined with mucosa that is responsible for the path from the frontal sinus to the nasal cavity, an untreated injury may lead to complications such as mucocele formation or chronic frontal sinusitis. Therefore, evaluation of FSOT is of clinical significance, with FSOT being diagnosed mostly by computed tomography or intraoperative dye. Several options are available to surgeons when treating FSOT injury, and they need to be familiar with these options to take the proper treatment measures in order to follow the treatment principle for FSOT, which is a safe sinus, and to reduce complications. This paper aimed to examine the surrounding anatomy, diagnosis, and treatment of FSOT.
Diagnosis ; Frontal Sinus* ; Frontal Sinusitis ; Mucocele ; Mucous Membrane ; Nasal Cavity ; Orbital Fractures ; Surgeons

Mucoceles are expansile, encapsulated, benign cystic lesions with the potential for adjacent bony remodeling and resorption. Paranasal mucoceles predominantly develop in the frontal sinuses (60%), followed in frequency by the ethmoidal (20-30%), maxillary (10%), and sphenoid (2-3%) sinuses. Nasal septal mucoceles develop in only very seldom cases. Septal mucoceles might develop from infected nasal septum or trauma. In the differential diagnosis of a midline septal mass, dermoid cyst, encephalocele, meningocele or intraseptal abscess should be considered. We present a case of nasal septal mucocele, which was managed by endoscopic excision and marsupialization.
Abscess ; Dermoid Cyst ; Diagnosis, Differential ; Encephalocele ; Frontal Sinus ; Meningocele ; Mucocele* ; Nasal Obstruction ; Nasal Septum*

Mucoceles are relatively common cystic lesions of the paranasal sinuses. However, mucocele of the nasal septum is extremely rare. We report a case of a mucocele present in this unusual location. Mucocele of the nasal septum should be considered in the differential diagnosis of a mass of the nasal septum and/or median canthal region. Nasal septal mucocele can be effectively treated with endoscopic marsupialization or complete excision.
Diagnosis, Differential ; Mucocele* ; Nasal Septum* ; Paranasal Sinuses

Cholesterol granuloma is a histopathological diagnosis with features of cholesterol clefts, foreign body giant cells, and macrophages filled with hemosiderin. It is commonly found in the mastoid or petrous apex, but the involvement of paranasal sinuses is very rare. Radiologically, cholesterol granuloma show typical findings of hyperintense signals on both T1- and T2-weighted images on magnetic resonance imaging (MRI). We report two cases of cholesterol granuloma in the sphenoid sinus, which were first misinterpreted as mucoceles due to unusual MRI images.
Cholesterol* ; Diagnosis ; Giant Cells, Foreign-Body ; Granuloma* ; Hemosiderin ; Macrophages ; Magnetic Resonance Imaging ; Mastoid ; Mucocele ; Paranasal Sinuses ; Sphenoid Sinus*

OBJECTIVE: Aimed to analyse the clinical features of the patients with sphenoid sinus mucocele, achieve earlier diagnosis and more timely intervention and decrease the occurrence of misdiagnoses. METHOD: A retrospective study was first conducted in patients with sphenoid sinus mucoele treated in Xiangya hospital from Jan 2000 to Jan 2015. Then literature reports on this disease were collected and analyzed from China National Knowledge Infrastructure (CNKI) and Wan Fang database. RESULT: We collected 82 patients with sphenoid sinus mucocele treated in Xiangya hospital. There were 52 patients presented with headache, 31 patients presented with visual impairment, 10 patients presented with cranial nerve palsy, 2 patients presented with exophthalmos, 15 patients presented with nasal symptoms, and 5 patients with no obvious symptoms. There was no significant difference for symptoms distribution between male and female patients (P > 0.05). Among 45 patients with headache as first symptom and 10 patients with ethmoid sinus mucocele, there were 18 patients and 8 patients subsequently suffering from visual impairment, respectively. We also collected 161 patients in literature except for enrolling, the 82 patients treated in Xiangya hospital, and found that headache was the most common symptom, followed by visual impairment, in the two independent cohorts. CONCLUSION To the best of our knowledge, this is the study of maximum sample for sphenoid sinus mucocele in China. Headache and visual impairment are the most common symptoms for sphenoid sinus mucocele. Surgical treatment should be early performed when the desease accompanied with headache or ethmoid sinus mucocele, to avoid other complications such as visual impairment and even blindness.
China ; Cranial Nerve Diseases ; etiology ; Databases, Factual ; Diagnostic Errors ; Ethmoid Sinus ; Exophthalmos ; etiology ; Female ; Headache ; etiology ; Humans ; Male ; Mucocele ; complications ; diagnosis ; pathology ; Paranasal Sinus Diseases ; Retrospective Studies ; Sphenoid Sinus ; pathology ; Vision Disorders ; etiology

Endoscopic sinus surgery is effective to nasal sinus mucocele with eye symptoms as main manifestation. It is very importment to raise the awareness of the disease and to prompt imaging examination. Three cases were reviewed. One mucocele was found in the frontal sinus ethmoid sinus,1 in the fronto-ethmoid sinus and 1 in the spheno-ethmoid sinus. All cases were preoperatively diagnosed by CT, MRI or intranasal endoscopy. Nasal sinus mucocele with eye symptoms as main manifestation should be early diagnosed. Endoscopic sinus surgery is a safe and effective method for the treatment of nasal sinus mucocele,and could be the primary choice for it. All cases were treated by nasal endoscopic sinus surgery. The majority of symptoms, such as exophthalmos, epiphora and diplopia, disappeared in all patients. However, vision recovery was observed only in some patients.
Diplopia ; complications ; Endoscopy ; Ethmoid Sinus ; pathology ; Exophthalmos ; complications ; Frontal Sinus ; pathology ; Humans ; Lacrimal Apparatus Diseases ; complications ; Magnetic Resonance Imaging ; Mucocele ; complications ; diagnosis ; Paranasal Sinus Diseases ; complications ; diagnosis

PURPOSE: Endometriosis is defined as functioning endometrial tissue outside of the uterus. Endometriosis of the appendix is uncommon. Its clinical presentation varies from asymptomatic to acute abdominal pain. The aims of this study were to describe our experience of managing patients with appendiceal endometriosis and to review the clinical characteristics of this medical condition. METHODS: Five cases of appendiceal endometriosis diagnosed between January 2007 and December 2012 were retrospectively reviewed. Patients treated for intra-abdominal endometriosis were excluded. RESULTS: The mean age at diagnosis was 33.8 years old. One patient was in the second trimester of pregnancy. Two patients were asymptomatic. Three patients had clinical symptoms including two with acute pain in the right lower quadrant and one with abdominal discomfort. Four patients showed appendiceal abnormalities in imaging studies including two cases of suspected mucocele and two cases of appendiceal infection. There were no suspicions of endometriosis of the appendix based on preoperative imaging studies. Three patients underwent appendectomy due to clinical symptoms, and two underwent incidental appendectomy combined with another operation. None of the patients received adjuvant therapy. CONCLUSION: Appendiceal endometriosis should be included in the differential diagnosis for acute abdominal pain, especially when women of childbearing age present with clinical symptoms of acute appendicitis.
Abdomen, Acute ; Abdominal Pain ; Acute Pain ; Appendectomy ; Appendicitis ; Appendix* ; Diagnosis ; Diagnosis, Differential ; Endometriosis* ; Female ; Humans ; Mucocele ; Pregnancy ; Pregnancy Trimester, Second ; Retrospective Studies ; Uterus

No abstract available.
Aged ; *Ethmoid Sinus ; Humans ; Male ; Mucocele/*complications/radiography ; Ocular Motility Disorders/diagnosis/*etiology ; Paranasal Sinus Diseases/*complications/radiography ; Tomography, X-Ray Computed

BACKGROUND: Lip skin diseases are common findings in dermatology. However, most dermatologists are not familiar with the clinical features of lip skin diseases due to the special characteristics of the lip. OBJECTIVE: This study aimed to evaluate the clinical and histopathological features of lip skin diseases. METHODS: We retrospectively reviewed 259 patients who underwent biopsy for labial diseases at the Department of Dermatology from January 2002 to December 2011. We compared the clinical and histopathological diagnoses and analyzed the rate of concurrence and labial tumor distribution. In addition, demographic and clinical features, including age, sex, location, and disease duration, were investigated. RESULTS: The mean age of the patients was 56.8 years and the male-to-female ratio was 1:0.77. Lip skin diseases accounted for 4.1% of all new patients during the study period, with the lower lip being the most commonly affected site (88.4%). The most common disease was actinic cheilitis (35.1%), followed by chronic cheilitis (11.6%), mucocele (10.0%), and squamous cell carcinoma (9.7%). The most common type of tumor was actinic cheilitis (54.8%), followed by mucocele (15.7%), squamous cell carcinoma (15.1%), hemangioma (4.2%), pyogenic granuloma (4.2%), keratoacanthoma (1.8%), and basal cell carcinoma (1.2%). Before the patients came to the university hospital, they received medical treatment at various clinics and departments, including dermatology clinics (55.3%), internal medicine (26.2%) and urology departments (10.7%), and general practitioners (9.7%). CONCLUSION: This study provides novel and useful data on the incidence and characteristics of lip skin diseases. Compared to previous studies, the frequency of lip tumors was relatively high and variable in this study. Based on these results, we advise physicians to, if in doubt, initially diagnose and treat for actinic cheilitis and labial tumors (especially squamous cell carcinoma) caused by long term exposure to the sun.
Actins ; Biopsy ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Cheilitis ; Dermatology ; Diagnosis ; General Practitioners ; Granuloma, Pyogenic ; Hemangioma ; Humans ; Incidence ; Internal Medicine ; Keratoacanthoma ; Lip* ; Mucocele ; Retrospective Studies ; Skin Diseases* ; Solar System ; Urology