1.Measurement and Assessment of Physical Activity by Information and Communication Technology.
Qun ZHANG ; Xi YANG ; Dan LIU ; Wen Hua ZHAO
Biomedical and Environmental Sciences 2017;30(6):465-472
		                        		
		                        			
		                        			This study provides explorative insights into the information and communication technology (ICT) for promoting the physical activity level. ICT has provided innovative ideas and perspectives for PA measurement, assessment, evaluation and health intervention. ICT that aims to increase exercise for the entire population should be of a well-oriented and easy-to-use design with the options of tailored and personalized feedback, coaching, and ranking and supporting; it should be capable of setting goals and working with a schedule and be accompanied by a website to provide overviews of the users' exercise results and progress.
		                        		
		                        		
		                        		
		                        			Exercise
		                        			;
		                        		
		                        			psychology
		                        			;
		                        		
		                        			Health Behavior
		                        			;
		                        		
		                        			Health Education
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Health Promotion
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Internet
		                        			;
		                        		
		                        			Mobile Applications
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Smartphone
		                        			
		                        		
		                        	
2.Development of skin moisture and body fat measurement system for mobile application.
Naihan HUANG ; Xiang CHEN ; Congzheng WANG ; Zhongfei DONG
Chinese Journal of Medical Instrumentation 2014;38(2):79-83
		                        		
		                        			
		                        			Integrating physiological parameters measurement into mobile devices is a development tendency of mobile healthcare. Measurement methods for skin moisture and body fat content are studied in this paper. Electrodes are designed for easy integration into mobile devices, and can be embedded in the cover of the mobile phone. Experiments were conducted to obtain a fast and easy measurement method. The results of evaluation show that the measurement system can achieve the same accuracy as commercial products (with correlation above 0.9 and root mean squared error below 4%) in skin moisture and body fat content measurement. Measurement of local-area body fat content showed a nearly linear positive correlation between local-area body fat content and local-area body impedance.
		                        		
		                        		
		                        		
		                        			Adipose Tissue
		                        			;
		                        		
		                        			Adiposity
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mobile Applications
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Skin Physiological Phenomena
		                        			;
		                        		
		                        			Skinfold Thickness
		                        			
		                        		
		                        	
3.Development of cardiac output monitoring system based on thermodilution method.
Jilun YE ; Yun JIANG ; Sai LUO ; Fan WANG ; Xu ZHANG
Chinese Journal of Medical Instrumentation 2014;38(5):337-340
		                        		
		                        			
		                        			Cardiac output (CO) monitoring is a crucial part of the hemodynamic status monitoring. So far, thermodilution method, which is clinically recognized as the gold standard method to monitor cardiac output, still has irreplaceable advantages. This paper mainly introduces the use of platform for cardiac output measurement based on thermodilution method, mainly including three parts: the hardware platform, software design and algorithm process. A large amount of test data of this system has been got by CO simulator testing in the laboratory and preliminary clinical tests in the hospital. The testing result showed that using the proposed system can achieve good accuracy and repeatability.
		                        		
		                        		
		                        		
		                        			Algorithms
		                        			;
		                        		
		                        			Cardiac Output
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Thermodilution
		                        			
		                        		
		                        	
4.Application of pulse contour cardiac output monitoring technique in hemodynamic monitoring in critical patients.
He FANG ; Xingfeng ZHENG ; Zhaofan XIA
Chinese Journal of Burns 2014;30(4):328-330
		                        		
		                        			
		                        			Pulse contour cardiac output (PiCCO) monitoring is a new type of invasive hemodynamic monitoring technology, which is more and more often applied in perioperative period and the patients suffering from multiple injuries, septic shock, and extensive burn. With PiCCO one is able to monitor patients' hemodynamic indexes safely, timely, accurately, and continuously to provide reference for judgment of patients' condition and proper quality and quantity of fluid administration. This technique has a good prospect in clinical application.
		                        		
		                        		
		                        		
		                        			Cardiac Output
		                        			;
		                        		
		                        			physiology
		                        			;
		                        		
		                        			Fluid Therapy
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			
		                        		
		                        	
5.Usefulness of an Implantable Loop Recorder in Patients with Syncope of an Unknown Cause.
Gu Hyun KANG ; Ju Hyeon OH ; Woo Jung CHUN ; Yong Hwan PARK ; Bong Gun SONG ; June Soo KIM ; Young Keun ON ; Seung Jung PARK ; June HUH
Yonsei Medical Journal 2013;54(3):590-595
		                        		
		                        			
		                        			PURPOSE: The mechanisms underlying syncope remain unknown in about 20% of patients with recurrent syncope. The implantable loop recorder (ILR) has been shown to be a useful diagnostic tool in patients with unexplained syncope even after negative initial evaluations. Nevertheless, ILR has rarely been used in clinical practice. MATERIALS AND METHODS: This study included 18 consecutive patients who had an ILR implanted at our center because of recurrent unexplained syncope after extensive diagnostic tests between February 2006 and June 2011. RESULTS: Diagnosis was confirmed in 10 (55.6%) of the 18 enrolled patients (13 males, 61+/-15 years). The confirmed diagnoses included sick sinus syndrome (n=6, 60%), advanced atrioventricular block (n=2, 20%) and ventricular tachyarrhythmia (n=2, 20%). The mean follow-up durations of the total study subjects and the diagnosed patients were 11.3+/-10.6 months and 5.6+/-9.2 months, respectively. Of the 10 diagnosed patients, 8 (80%) were diagnosed within 6 months of loop recorder implantation. CONCLUSION: ILR may be a valuable and effective diagnostic tool for patients with unexplained syncope.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Electrocardiography/instrumentation/methods
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Monitoring, Physiologic/instrumentation/methods
		                        			;
		                        		
		                        			Syncope/*diagnosis/etiology
		                        			
		                        		
		                        	
6.Clinical study of neonatal cardiac output measurement methods.
Man-li ZHENG ; Xin SUN ; Jing ZHONG ; Shao-ru HE ; Wei PAN ; Cheng-cheng PANG ; Yun-xia SUN ; Yu-mei LIU
Chinese Journal of Pediatrics 2013;51(1):58-63
OBJECTIVETo assess agreement between the ultrasonic cardiac output monitor (USCOM) and conventional echocardiography (ECHO) in the measurement of cardiac output in newborn infants, investigate the accuracy and clinical utility of the USCOM in healthy neonates. To explore a more convenient, faster, more accurate hemodynamic monitoring method, for improving the outcome of the critically ill neonates.
METHODFrom October 1(st), 2011 to March 31(st), 2012, a total of 49 infants were included, 20 were term infants, 29 were preterm infants. Cardiac outputs were measured by both ultrasonic cardiac output monitor and echocardiography in all the infants, 60 times measurements were done in both the term infants the preterm infants. The cardiac output of the left and right ventricles, heart rate, diameter and velocity time integral of the aortic valve and pulmonary artery valve of each infant were recorded. The consistency of two methods was analyzed as described by Bland-Altman.
RESULTTerm the term infant group includea 20 term infants, 11 were male and 9 were female, the mean gestational age were (38.1 ± 0.56) weeks, mean age were (2 ± 1) days, mean weight were (3.2 ± 0.29) kg, mean Apgar score were 10. The mean left ventricular output measured by Echo was (242.3 ± 38.9) ml/(kg·min), measured by USCOM was (211.7 ± 38.5) ml/(kg·min); The mean right ventricular output measured by ECHO was (318.9 ± 47.0) ml/(kg·min), measured by USCOM was (340.7 ± 76) ml/(kg·min). Agreement between Echo and USCOM for left ventricular output (LVO) was (bias, ± limits of agreement, mean % error): (30.6 ± 51.1) ml/(kg·min), 21%, and for right ventricular output (RVO): (-21.8 ± 105) ml/(kg·min), 33.2%. The diameter of the aortic valve and pulmonary artery valve measured by conventional echocardiography were significantly larger than that estimated by ultrasonic cardiac output monitor (P < 0.001). The velocity time integral of the pulmonary artery valve measured by ultrasonic cardiac output monitor were significantly larger than measured by conventional echocardiography (P < 0.001). The heart rate, velocity time integral of the aortic valve measured by two methods had no significant differences (P > 0.05). The preterm neonates group included 29 preterm infants, 18 were male and 11 were female, the mean gestational age were (32.6 ± 2.8) weeks, mean age were (2 ± 1) days, mean weight were (1.88 ± 0.57) kg. All the infants were diagnosis as preterm infant, low birth weight. The mean left ventricular output measured by ECHO was (259.8 ± 70) ml/(kg·min), measured by USCOM was (235.6 ± 61.8) ml/(kg·min), the mean right ventricular output measured by ECHO was (318.9 ± 47.0) ml/(kg·min), measured by USCOM was (340.7 ± 76) ml/(kg·min). Agreement between Echo and USCOM for left ventricular output (LVO) was (bias, ± limits of agreement, mean % error): (24.1 ± 71.2) ml/(kg·min), 27.4%, and for right ventricular output (RVO): (-29.5 ± 192.9) ml/(kg·min), 51.8%. The diameter of the aortic valve and pulmonary artery valve measured by conventional echocardiography were significantly larger than estimated by ultrasonic cardiac output monitor (P < 0.001). The velocity time integral of the pulmonary artery valve measured by USCOM were significantly larger than that measured by conventional echocardiography (P < 0.001). The heart rate, velocity time integral of the aortic valve measured by two methods had no significant differences (P > 0.05).
CONCLUSIONAgreement between USCOM and conventional ECHO in the LVO measurement is acceptable, both in the term group and the preterm group. LVO measurement measured by USCOM is recommended. The accuracy and clinical utility of the USCOM in neonates is acceptable. USCOM is a convenient, fast and accurate hemodynamic monitoring method in neonates. While the agreement between USCOM and conventional ECHO in the RVO measurement is poor, especially in the preterm group, the results of the RVO cannot be considered interchangeable in the two methods.
Cardiac Output ; Echocardiography, Doppler ; instrumentation ; methods ; Female ; Heart Rate ; physiology ; Hemodynamics ; physiology ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Intensive Care, Neonatal ; Male ; Monitoring, Physiologic ; methods ; Reproducibility of Results ; Sensitivity and Specificity ; Ventricular Function ; physiology
7.Research of micro sleeping monitor and evaluation system.
Caibing ZHU ; Yantao SONG ; Lanlan WEI ; Jilun YE ; Xu ZHANG
Chinese Journal of Medical Instrumentation 2013;37(6):414-431
		                        		
		                        			
		                        			By studying of the pathology of human sleep and respiration disorder diseases, the method of sleep and respiration measurement, the evaluation index, a kind of micro sleep monitor and evaluation system was designed. Based on the methods of spectrum absorption and force changing, using high performance pulse oxygen saturation monitoring technology and respiration monitoring technology, developing a low-cost, high usability sleep monitor system which is convenience for family using. It can measure the signal of human oxygen saturation and chest respiration, can improve the quality of signal and reliable from arithmetic and sensor installing.
		                        		
		                        		
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Oximetry
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Respiration
		                        			;
		                        		
		                        			Sleep
		                        			;
		                        		
		                        			physiology
		                        			;
		                        		
		                        			Software Design
		                        			
		                        		
		                        	
8.Development of mobile monitor for risk factor control on chronic disease.
Danhua YAO ; Chaoyang ZHU ; Jiali BAO
Chinese Journal of Medical Instrumentation 2013;37(6):411-420
		                        		
		                        			
		                        			In order to improve the control rate of risk factors of chronic disease, it is developed a status control method of risk factor and its mobile monitor. The monitor uses 32 bit RISC microprocessor of S3C2410X as a controller based on ARM920T core, and MC35i cellular engine GSM/GPRS supported by SIEMENS as the communication unit. The proving tests show that the physical activity, diet, smoking and alcohol of the controlled people can be controlled using the status control method, and the monitor plays a key role in the method. The conclusion is that status control method and mobile monitor can become an alternation method and technology for the risk factor control of chronic disease.
		                        		
		                        		
		                        		
		                        			Chronic Disease
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			Equipment Design
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Risk Factors
		                        			
		                        		
		                        	
9.Comprehensive testing system for cardiorespiratory interaction research.
Zhengbo ZHANG ; Buqing WANG ; Weidong WANG ; Jiewen ZHENG ; Hongyun LIU ; Kaiyuan LI ; Congcong SUN ; Guojing WANG
Journal of Biomedical Engineering 2013;30(2):395-402
		                        		
		                        			
		                        			To investigate the modulation effects of breathing movement on cardiovascular system and to study the physiological coupling relationship between respiration and cardiovascular system, we designed a comprehensive testing system for cardiorespiratory interaction research. This system, comprising three parts, i. e. physiological signal conditioning unit, data acquisition and USB medical isolation unit, and a PC based program, can acquire multiple physiological data such as respiratory flow, rib cage and abdomen movement, electrocardiograph, artery pulse wave, cardiac sounds, skin temperature, and electromyography simultaneously under certain experimental protocols. Furthermore this system can be used in research on short-term cardiovascular variability by paced breathing. Preliminary experiments showed that this system could accurately record rib cage and abdomen movement under very low breathing rate, using respiratory inductive plethysmography to acquire respiration signal in direct-current coupling mode. After calibration, this system can be used to estimate ventilation non-intrusively and correctly. The PC based program can generate audio and visual biofeedback signal, and guide the volunteers to perform a slow and regular breathing. An experiment on healthy volunteers showed that this system was able to guide the volunteers to do slow breathing effectively and simultaneously record multiple physiological data during the experiments. Signal processing techniques were used for off-line data analysis, such as non-invasive ventilation calibration, QRS complex wave detection, and respiratory sinus arrhythmia and pulse wave transit time calculation. The experiment result showed that the modulation effect on RR interval, respiratory sinus arrhythmia (RSA), pulse wave transit time (PWTT) by respiration would get stronger with the going of the slow and regular breathing.
		                        		
		                        		
		                        		
		                        			Algorithms
		                        			;
		                        		
		                        			Artifacts
		                        			;
		                        		
		                        			Autonomic Nervous System
		                        			;
		                        		
		                        			physiopathology
		                        			;
		                        		
		                        			Diagnosis, Computer-Assisted
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Electrocardiography
		                        			;
		                        		
		                        			Equipment Design
		                        			;
		                        		
		                        			Heart
		                        			;
		                        		
		                        			physiology
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lung
		                        			;
		                        		
		                        			physiology
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Respiration
		                        			;
		                        		
		                        			Respiratory Mechanics
		                        			;
		                        		
		                        			physiology
		                        			
		                        		
		                        	
10.Development of a wrist wearing and remote heart rate alarm apparatus.
Ruibin ZHAO ; Yanjun MENG ; Wei ZHANG ; Yanru WU ; Jingjing ZHANG ; Zhenzhong FAN
Journal of Biomedical Engineering 2013;30(2):292-295
		                        		
		                        			
		                        			We have developed a new wrist wearing heart rate monitoring alarm apparatus, which can detect the patients' real-time pulse waves. When the abnormal heart rate appears or pulse disappears, the monitoring alarm will sound and dial the remote telephone for help simultaneously. This apparatus uses the switch circuit to control the keyboard of mobile phone, and dials remote telephone in the help of mature technology and communication platform of mobile phones. The intelligent program can distinguish digital pulse signal, pick out the correct cycle of heartbeat intelligently. The new wrist wearing heart rate monitoring alarm apparatus will calculate an average heart rate when it captures consecutively five correct electrocardiograph waveforms. It really provides a simple, inexpensive and effective way for the patients with heart disease.
		                        		
		                        		
		                        		
		                        			Automation
		                        			;
		                        		
		                        			Equipment Design
		                        			;
		                        		
		                        			Heart Rate
		                        			;
		                        		
		                        			physiology
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Monitoring, Physiologic
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Pulse
		                        			;
		                        		
		                        			Remote Sensing Technology
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Signal Processing, Computer-Assisted
		                        			;
		                        		
		                        			Telemetry
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
            
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