Search Results

4.Combined Use of Intrathecal Opioids and Dexmedetomidine in the Management of Neuropathic Pain.

Mohamed Amin GHOBADIFAR ; Farideh POURGHASHDAR ; Armin AKBARZADEH ; Zahra MOSALLANEJAD

The Korean Journal of Pain 2015;28(2):156-157

5.Pelvic Incidence as a Determinant for Chronic Low Back Pain: Few Comments.

Mohamed Amin GHOBADIFAR

Asian Spine Journal 2015;9(1):149-150

6.The potential role of granulosa cells in the maturation rate of immature human oocytes and embryo development: A co-culture study.

Bahia Namavar JAHROMI ; Zahra MOSALLANEZHAD ; Najmeh MATLOOB ; Maryam DAVARI ; Mohamed Amin GHOBADIFAR

Clinical and Experimental Reproductive Medicine 2015;42(3):111-117

OBJECTIVE: In order to increase the number of mature oocytes usable for intracytoplasmic sperm injection (ICSI), we aimed to investigate the effect of co-culturing granulosa cells (GCs) on human oocyte maturation in vitro, the fertilization rate, and embryo development. METHODS: A total of 133 immature oocytes were retrieved and were randomly divided into two groups; oocytes that were cultured with GCs (group A) and oocytes that were cultured without GCs (group B). After in vitro maturation, only oocytes that displayed metaphase II (MII) underwent the ICSI procedure. The maturation and fertilization rates were analyzed, as well as the frequency of embryo development. RESULTS: The mean age of the patients, their basal levels of follicle-stimulating hormone, and the number of oocytes recovered from the patients were all comparable between the two study groups. The number of oocytes that reached MII (mature oocytes) was 59 out of 70 (84.28%) in group A, compared to 41 out of 63 (65.07%) in group B (p=0.011). No significant difference between fertilization rates was found between the two study groups (p=0.702). The embryo development rate was higher in group A (33/59, 75%) than in group B (12/41, 42.85%; p=0.006). The proportion of highest-quality embryos and the blastocyst formation rate were significantly lower in group B than in group A (p=0.003 and p<0.001, respectively). CONCLUSION: The findings of the current study demonstrate that culturing immature human oocytes with GCs prior to ICSI improves the maturation rate and the likelihood of embryo development.
Blastocyst ; Coculture Techniques* ; Embryonic Development* ; Embryonic Structures* ; Female ; Fertilization ; Follicle Stimulating Hormone ; Granulosa Cells* ; Humans* ; In Vitro Oocyte Maturation Techniques ; Metaphase ; Oocytes* ; Pregnancy ; Sperm Injections, Intracytoplasmic

7.Safety of Epidural Steroid Injection Methods in the Management of Recurrent Lumbar Disc Herniation: Few Comments.

Mohamed Amin GHOBADIFAR ; Farideh POURGHARDASH ; Armin AKBARZADEH ; Zahra MOSALLANEJAD

Asian Spine Journal 2015;9(2):311-312

8.Dehydroepiandrosterone Sulfate as a Risk Factor for Premature Myocardial Infarction: A Comparative Study.

Mohammad SHOJAIE ; Mohammad Yaghoub RAJPOUT ; Armin ABTAHIAN ; Azadeh Esmail POUR ; Mohamed Amin GHOBADIFAR ; Armin AKBARZADEH

Korean Journal of Family Medicine 2015;36(1):1-9

BACKGROUND: This study aimed to evaluate some of the major risk factors of myocardial infarction including dehydroepiandrosterone sulfate in patients with premature myocardial infarction (age <50 years old) and myocardial infarction (age > or =50 years). METHODS: This is a parallel case-control study on 50 premature myocardial infarction patients and 50 myocardial infarction patients. We also recruited 50 matched participants for each of the two groups. Patients and their control groups were assessed for dehydroepiandrosterone sulfate serum level, diabetes mellitus, hyperlipidemia, hypertriglyceridemia, and hypertension. In addition, family history of cardiovascular disease and current smoking was recorded. Univariate and multivariate logistic regression analyses were performed to evaluate predictors of premature myocardial infarction and myocardial infarction. RESULTS: No significant differences were observed between the demographic data of patients and their controls. The dehydroepiandrosterone sulfate serum level was significantly higher in patients with premature myocardial infarction compared with controls. Multivariate logistic regression analysis revealed only serum dehydroepiandrosterone sulfate dehydroepiandrosterone sulfate level to be significantly associated with premature myocardial infarction (odds ratio, 2.65; 95% confidence interval, 1.44 to 4.877; P = 0.002). Additionally, hypertension was found to be associated with myocardial infarction. CONCLUSION: Higher levels of serum dehydroepiandrosterone sulfate level are associated with premature myocardial infarction but not with myocardial infarction, and this association is independent of the effects of other risk factors.
Cardiovascular Diseases ; Case-Control Studies ; Dehydroepiandrosterone Sulfate* ; Diabetes Mellitus ; Humans ; Hyperlipidemias ; Hypertension ; Hypertriglyceridemia ; Logistic Models ; Myocardial Infarction* ; Risk Factors* ; Smoke ; Smoking

9.Risks and Pitfalls of Epidural Injections during Management of Lumbar Disc Herniation: Few Comments.

Mohammad Sadegh SANIE ; Mohamed Amin GHOBADIFAR

The Korean Journal of Pain 2015;28(3):217-218

10.Which Methods of Epidural Steroid Injections Is More Effective in Reducing the Radicular Pain; Transforaminal or Interlaminar?.

Mohamed Amin GHOBADIFAR ; Armin AKBARZADEH ; Zahra MOSALLANEJAD

The Korean Journal of Pain 2015;28(1):64-65

1.Blood glucose level after febrile convulsion.

2.Blood glucose level after febrile convulsion.

3.An Update on the Management of Diabetic Neuropathic Pain: A Few Comments.