OBJECTIVES: We estimated the population prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including unreported infections, through a Korea Seroprevalence Study of Monitoring of SARS-CoV-2 Antibody Retention and Transmission (K-SEROSMART) in 258 communities throughout Korea. METHODS: In August 2022, a survey was conducted among 10,000 household members aged 5 years and older, in households selected through two stage probability random sampling. During face-to-face household interviews, participants self-reported their health status, COVID-19 diagnosis and vaccination history, and general characteristics. Subsequently, participants visited a community health center or medical clinic for blood sampling. Blood samples were analyzed for the presence of antibodies to spike proteins (anti-S) and antibodies to nucleocapsid proteins (anti-N) SARS-CoV-2 proteins using an electrochemiluminescence immunoassay. To estimate the population prevalence, the PROC SURVEYMEANS statistical procedure was employed, with weighting to reflect demographic data from July 2022. RESULTS: In total, 9,945 individuals from 5,041 households were surveyed across 258 communities, representing all basic local governments in Korea. The overall population-adjusted prevalence rates of anti-S and anti-N were 97.6% and 57.1%, respectively. Since the Korea Disease Control and Prevention Agency has reported a cumulative incidence of confirmed cases of 37.8% through July 31, 2022, the proportion of unreported infections among all COVID-19 infection was suggested to be 33.9%. CONCLUSIONS The K-SEROSMART represents the first nationwide, community-based seroepidemiologic survey of COVID-19, confirming that most individuals possess antibodies to SARS-CoV-2 and that a significant number of unreported cases existed. Furthermore, this study lays the foundation for a surveillance system to continuously monitor transmission at the community level and the response to COVID-19.

Background: The aim of this study was to evaluate the short-term and long-term results of surgical treatment for native valve endocarditis (NVE) and to investigate the risk factors associated with mortality. Methods: Data including patients’ characteristics, operative findings, postoperative results, and survival indices were retrospectively obtained from Hallym University Sacred Heart Hospital. Results: A total of 29 patients underwent surgery for NVE (affecting the mitral valve in 20 patients and the aortic valve in 9) between 2003 and 2017. During the follow-up period (median, 46.9 months; interquartile range, 19.1–107.0 months), the 5-year survival rate was 77.2%. In logistic regression analysis, body mass index (p=0.031; odds ratio [OR], 0.574; 95% confidence interval [CI], 0.346–0.951), end-stage renal disease (ESRD) (p=0.026; OR, 24.0; 95% CI, 1.459–394.8), and urgent surgery (p=0.010; OR, 34.5; 95% CI, 2.353–505.7) were significantly associated with in-hospital mortality. Based on Cox proportional hazard regression analysis, the statistically significant predictors of long-term outcomes were hypertension, ESRD, and urgent surgery. Conclusion Surgical treatment for NVE is associated with considerable mortality. The in-hospital mortality and 5-year survival rates of this study were 13.8% and 77.2%, respectively. Underlying conditions, including hypertension and ESRD, and urgent surgery were independent risk factors for unfavorable outcomes.

PURPOSE: Recently TF-adaptive movement is developed in order to increase the durability of TF files. The purpose of this study was to assess the effects of adaptive movement on durability and performance of twisted files. MATERIALS AND METHODS: Resin blocks simulating artificial J-shape canals were used for this study. In TFC group, TF-adaptive ML-1 (25/.08 size) files were used to prepare the canals under continuous rotation 500 rpm/4.0 Ncm. In TFA group, TF-adaptive ML-1 (25/.08 size) files were used to prepare the canals under adaptive movement. After preparing each artificial canal, TF files were observed under dental microscope for assessing existence of unwinding, distortion, and fracture. If unwinding of flute was observed, the number of artificial canals until unwinding of flute occurs was recorded. Required time until instruments reach working length and distance of unwinded portion of files from D0 were measured. All test results were conducted by Mann-Whitney U test at a 0.05 level of significance. RESULTS: No NiTi instrument's separation was observed. Number of resin blocks until file unwinding happens and working time was significantly high in TFA group compared to TF group. Distance of distortion from D0 didn't show significant difference between TFA, TF groups. CONCLUSION: The number of resin blocks prepared until unwinding happens and working time were significantly high in TFA group. The location of unwinding showed no significant difference between 2 groups. Adaptive movement increased the number of canals prepared until unwinding occurs and working time of twisted files.
Filing ; Movement ; Root Canal Preparation

In adults, most intussusceptions develop from a lesion, usually a benign or malignant neoplasm, and can occur at any site in the gastrointestinal tract. Intussusception in the proximal gastrointestinal tract is uncommon, and gastro-gastric intussusception is extremely rare. We present a case of gastro-gastric intussusception secondary to a primary gastric lymphoma. An 82-year-old female patient presented with acute onset chest pain and vomiting. Abdominal CT revealed a gastro-gastric intussusception. We performed upper gastrointestinal endoscopy, revealing a large gastric mass invaginated into the gastric lumen and distorting the distal stomach. Uncomplicated gastric reposition was achieved with endoscopy of the distal stomach. Histological evaluation of the gastric mass revealed a diffuse large B cell lymphoma that was treated with chemotherapy.
Adult ; Aged, 80 and over ; Chest Pain ; Drug Therapy ; Endoscopy ; Endoscopy, Gastrointestinal ; Female ; Gastrointestinal Tract ; Humans ; Intussusception* ; Lymphoma* ; Lymphoma, B-Cell ; Stomach ; Tomography, X-Ray Computed ; Vomiting

This is a case report of chronic maxillary sinusitis caused by root canal overfilling of Calcipex II (Techno-Dent). A 60 year-old male complained of dull pain in the right maxillary molar area after complicated endodontic treatment using Calcipex II paste and was finally diagnosed with a chronic maxillary sinusitis through a clinical and radiological observation. In the biopsy examination, the periapical granuloma contained a lot of dark and translucent Calcipex II granules which were not stained with hematoxylin and eosin. They were usually engulfed by macrophages but rarely resorbed, resulting in scattering and migrating into antral mucosa. Most of the Calcipex II granules were also accumulated in the cytoplasms of secretory columnar epithelial cells, and small amount of Calcipex II granules were gradually secreted into sinus lumen by exocytosis. However, chronic granulomatous inflammation occurred without the additional recruitment of polymorphonuclear leukocytes (PMNs) and lymphocytes, and many macrophages which engulfed the Calcipex II granules were finally destroyed in the processes of cellular apoptosis. It is presumed that Calcipex II granules are likely to have a causative role to induce the granulomatous foreign body inflammation in the periapical region, and subsequently to exacerbate the chronic maxillary sinusitis in this study.
Apoptosis ; Biopsy ; Cytoplasm ; Dental Pulp Cavity* ; Eosine Yellowish-(YS) ; Epithelial Cells ; Exocytosis ; Foreign Bodies ; Granuloma, Foreign-Body ; Hematoxylin ; Humans ; Inflammation ; Lymphocytes ; Macrophages ; Male ; Maxillary Sinus* ; Maxillary Sinusitis* ; Middle Aged ; Molar ; Mucous Membrane ; Neutrophils ; Periapical Granuloma

BACKGROUND: This study was undertaken to assaythe effectiveness of transforaminal epidural steroid injections (TFESIs) for sciatica and to identify potential predictors related to treatment outcome. METHODS: TFESIs were performed in 150 patients between August 2006 and March 2007. Seventy-five patients (35 women, 40 men; mean age, 59.1 years), who met the inclusion criteria, were studied. Therapeutic effects were evaluated twoweeks after injection. The following potential outcome predictors analyzed were as follows: one level vs. two level injection, Beck depression inventory score (<13, 14-19, >20), Beck anxiety inventory score (<7, 8-15, >16), cause of radiculopathy (spinal stenosis vs. herniated disk), gender, duration of radiculopathy (<6 months, 6-12 months, >6 months), and Oswestry disability index score (<30, 31-60, >60). The relationships between possible outcome predictors and therapeutic effects were evaluated. RESULTS: Forty-nine of the 75 patients (65.3%) had a satisfactory result two weeks after TFESIs. Of these, twenty-four of the 46 patients (52.2%) were treated by a one level injection and 25 (89.3%) of the 29 patients were treated by a two level injection. This outcome was statistically significant (P < 0.01). None of the other potential outcome predictors showed any statistical difference. CONCLUSIONS: TFESI is recommended as an effective method of managing radiculopathy. Two-level injectionsmay result in a better outcome than a one-level injection.
Anxiety ; Constriction, Pathologic ; Depression ; Female ; Humans ; Radiculopathy ; Sciatica

STATEMENT OF PROBLEM: Alteration of tooth function is assumed to be changed by stress/strain on the adjacent alveolar bone, producing changes in morphology similar to those described for other load-bearing bones. When teeth are removed, opposing teeth will not be functioned. When edentulous area is restored by implant prostheses, opposing teeth will be received physiologic mechanical stimuli. PURPOSE: The aim of this study was to evaluate the bone changes around the teeth opposing implant restoration installed mandibular posterior area. MATERIAL AND METHOD: Eight patients who had mandibular posterior edentulous area were treated with implants. Radiographs of the opposing teeth were taken at implant prostheses delivery(baseline), 3 months, and 6 months later. Customized film holding device was fabricated to standardize the projection geometry for serial radiographs of opposing teeth. Direct digital image was obtained. Gray values of region of interest at each digital image were measured and compared according to time lapse. Repeated measured analysis of variance and post-hoc Scheffe's test were performed at the 95% significance level. RESULTS: Alveolar bone changes around the natural teeth opposing the posterior implant in mandible showed statistically significant difference compared to control group(P<0.05). And gray values of alveolar bone around the teeth opposing implants were increased. There were no statistically significant differences of alveolar bone changes between crestal group and middle group and between mesial group and distal group according to time lapse(P>0.05). There were no statistically significant differences of alveolar bone changes among mesial-crestal group, mesial-middle group, distal-crestal group, distal-middle group, and control group(P>0.05). CONCLUSION: Alveolar bone around the natural teeth opposing the implant prosthesis showed gradual bony apposition.
Humans ; Mandible* ; Prostheses and Implants ; Tooth* ; Weight-Bearing

BACKGROUND: The overall rate of renal complication after surgery on the suprarenal aorta remains high. In this study, the changes in renal blood flow (RBF), urinary oxygen tension (PuO2), renal vascular resistance (RVR), and urinary volume following fenoldopam administration were investigated in supraceliac aortic cross-clamping and unclamping animal model. METHODS: Twelve dogs were divided into two groups; control group (n = 6), fenodopam group (n = 6). After brachial, femoral, and pulmonary arterial catheterization, midline abdominal incision was made. For the aortic cross-clamping the supraceliac aorta was exposed. A doppler flowmeter probe was placed around right renal artery. A ureteral catheter was positioned at the right renal pelvis to measure urine volume and urinary oxygen tension (PuO2). In fenoldopam group, 0.5microgram/kg/min of fenoldopam was administered immediately before suprarenal aortic reperfusion. Systemic hemodynamics, renal blood flow, renal vascular resistance, PuO2, and urine volume were compared between two groups. RESULTS: The systemic hemodynamics were not significantly different between the two groups throughout the experiment. After aortic reperfusion, the RVR significantly increased in control group, but the RVR in fenoldopam group remained to baseline level. The urine output, RBF, and PuO2 significantly increased in fenoldopam group compared to control group. BUN and serum creatinine were not different between the two groups. CONCLUSIONS: High dose of fenoldopam administration reverse ischemic renal insufficiency after supraceliac aortic cross clamping.
Animals ; Aorta ; Catheterization ; Catheters ; Constriction ; Creatinine ; Dogs ; Fenoldopam* ; Flowmeters ; Hemodynamics ; Kidney Pelvis ; Models, Animal ; Oxygen ; Renal Artery ; Renal Circulation ; Renal Insufficiency ; Reperfusion ; Urinary Catheters ; Vascular Resistance

An intestinal obstruction is a common cause of acute abdominal diseases which need emergency measures. Sigmoid volvulus is one of rare causes of colonic obstruction and occupies 2~3% of its causes in Korea. Volvulus requires a prompt diagnosis and decompression in order to prevent its progression to strangulation and gangrene. Although 90% of sigmoid volvulus can be diagnosed just by plain abdominal x-ray, computed tomography or barium enema can be done for more accurate diagnoses. For the successful treatment, accurate early examination, endoscopic reduction and surgical colonic resection are required. Endoscopic reduction has low mortality but is liable to recur, whereas emergency colonic resection has little recurrence rate but a high mortality. We experienced a case of a sigmoid volvulus in a 55-year-old male who companied of sudden abdominal pain. After diagnosed as sigmoid volvulus through plain abdominal x-ray and abdominal computed tomography, endoscopic reduction was done in the early period of development, and the sigmoid resection was performed after 7 days. We report our experience with a review of the literature regarding the diagnosis and treatment of sigmoid volvulus.
Abdominal Pain ; Barium ; Colon* ; Colon, Sigmoid* ; Decompression ; Diagnosis ; Emergencies* ; Enema ; Gangrene ; Humans ; Intestinal Obstruction ; Intestinal Volvulus* ; Korea ; Male ; Middle Aged ; Mortality ; Recurrence

The purpose of this study was to compare the eating habit, food intake frequency and preferred food and taste of juvenile delinquents (100 numbers) and male high school students (100 numbers), using questionnaires from August to October 2004. 1) It was shown that the juvenile delinquents took more unbalanced diet (p <0.05), smoking (p <0.001) and drinking (p <0.001) than general students, while general students had more eating between meals (p <0.01). 2) The intake of food was a significant difference in white rices (p <0.01), bibimbab (p <0.001), kimbab (p <0.001), fried rice (p <0.001), ramen (p <0.001), jajangmyun (p <0.001), jambong (p <0.001), hamburger (p <0.001), pizza (p <0.001) and breads (p <0.05). The juvenile delinquents took more major food than that of general students in all the items except for white rice. It was observed, then, that the juvenile delinquents showed more intake of such subsidiary foods as bulgoki (p <0.001), roasted thin pork chops (p <0.001), grilled pork belly (p <0.001), pork cutlet (p <0.01), sweet and sour pork (p <0.001), chicken with ginseng (p <0.001), fried chicken (p <0.001), kimchi pot stew (p <0.01) and zucchini (p <0.05) than general students, with general students taking more kimchi (p <0.01) and fried or boiled soybean curd (p <0.01). The intake of dessert was a significant difference in yogurt (p <0.01), orange juice (p <0.001), cola (p <0.001), soft drinks (p <0.001), ion drinks (p <0.001), coffee (p <0.001), apple (p <0.01), banana (p <0.001), orange (p <0.001), cake (p <0.001), hot dog (p <0.001), ddokbokgi (p <0.01), mandu (p <0.001), fried fish paste (p <0.05), steamed korean sausage (p <0.001), fried foods (p <0.05), hem & sausage (p <0.001), cheese (p <0.001), ice-cream (p <0.001), candy (p <0.01), chocolate (p <0.001), mayonnaise (p <0.05), jam (p <0.01) and butter & margarine (p <0.01). Then, the juvenile delinquents were shown to entirely have more intake of all the desserts than those of general students. 3) Regarding preference of foods, it was shown that the juvenile delinquents preferred cereals (p <0.05), grilled pork belly (p <0.001), chicken with ginseng (p <0.01), anchovies and small fish (p <0.05), chicken with ginseng (p <0.05), seasoned spinach (p <0.001), seasoned zucchini (p <0.001), milk (p <0.05), coffee (p <0.001) and butter & margarine (p <0.05) while general students did egg (p <0.01), soybean sprout soup (p <0.001), boiled or fried potato (p <0.05), seasoned soybean sprout (p <0.05), boiled or fried soybean curd (p <0.01), fried foods (p <0.01) and snack (p <0.05). For their preference of tastes, hot taste (p <0.01) was higher in the juvenile delinquents. 4) Under general environments there was a change of the difference in their behaviour of pork cutlet (p <0.01) intake in accordance with other family and of milk (p <0.001) and butter & margarine (p <0.05) preference in accordance with growth in a big city between the two groups.
Animals ; Bread ; Butter ; Cacao ; Candy ; Carbonated Beverages ; Edible Grain ; Cheese ; Chickens ; Citrus sinensis ; Coffee ; Cola ; Diet ; Dogs ; Drinking ; Eating* ; Food Habits* ; Food Preferences ; Humans ; Male* ; Margarine ; Meals ; Milk ; Musa ; Ovum ; Panax ; Seasons ; Smoke ; Smoking ; Snacks ; Solanum tuberosum ; Soybeans ; Spinacia oleracea ; Steam ; Surveys and Questionnaires ; Yogurt