1.Effects of timing of endoscopy on clinical outcomes of cirrhotic patients with acute variceal bleeding in a tertiary hospital.
Alinda Mae C. GORDOLA ; Eric B. YASAY
Acta Medica Philippina 2025;59(Early Access 2025):1-8
BACKGROUND AND OBJECTIVE
Evidence regarding the impact of performing endoscopy within 12 hours of variceal bleeding (VB) on outcomes is inconclusive, and there is a lack of local data on this topic. This study aimed to determine if the timing of endoscopy is associated with clinical outcomes.
METHODSThis was a single-center retrospective cohort study which included adult cirrhotic patients admitted for VB from January 2016 to September 2022. The primary outcomes were in-hospital and 6-week mortality. Secondary outcomes included 5-day rebleeding, length of hospital stay (LOS), and blood transfusion requirements (BTR). The relationships between timing of endoscopy and outcomes were evaluated using regression analysis.
RESULTSIn 140 patients, 5.7% underwent urgent endoscopy (?12 hours). The overall median door-to-endoscopy time (DET) was 39.4 hours (IQR 20.0-73.4). The overall in-hospital mortality, 6-week mortality, and 5-day rebleeding rates were 12.9%, 11.4%, and 8.6%, respectively, without significant variability at different DET (p >0.05). Prolonged LOS was evident when endoscopy was delayed to >12 hours from admission (3.5 [IQR 2.25-5.75] vs 6 days [IQR 4-9.75], p = 0.021), while BTR was greater starting at endoscopies performed at >24 hours from admission (1 [0-2] vs 2 units [1-3], p = 0.000). Delayed endoscopy was significantly correlated with LOS (Beta 0.316, SE 0.011, p = 0.000) and BTR (Beta 0.214, SE 0.469, p = 0.003), but not with mortality and early rebleeding.
CONCLUSIONTiming of endoscopy may be independent of mortality and early rebleeding. Timely endoscopy may shorten hospitalization and decrease need for blood transfusion. Other factors affecting clinical outcomes may be at play.
Human ; Cirrhosis ; Fibrosis ; Endoscopy
2.Flexible endoscopic management of foreign body ingestion in children: A ten-year single-center retrospective study in the Philippines.
Jeremiah C. TORRICO ; Germana Emerita V. GREGORIO
Acta Medica Philippina 2025;59(Early Access 2025):1-12
BACKGROUND AND OBJECTIVE
Foreign body (FB) ingestion is a common pediatric concern in the Philippines, but local studies on flexible endoscopic management are lacking. This study aimed to describe the clinical profile and outcomes of children referred for flexible endoscopic management and identify factors associated with poor outcomes.
METHODSThis retrospective cohort study included 145 patients agedRESULTS
Most FB ingestions (96.55%) were accidental, with coins as the most common FB (56.55%). Patients were admitted an average of 40.42 hours post-ingestion and referred for endoscopy within 9.28 hours. Flexible endoscopy was performed in 44.83% of cases, with a 98.46% success rate and an average procedure time of 32.25 minutes. Spontaneous passage occurred in 50.34% of cases. Poor outcomes were linked to age 48 hours; OR: 15.43, p = 0.0181), and prolonged procedures (>30 minutes; OR: 12, p = 0.0318). Good outcomes were associated with unremarkable physical exams (OR: 0.078; p = 0.0018), early admission (CONCLUSION
Flexible endoscopy is effective and safe for FB extraction in children. Early admission and timely intervention significantly improve outcomes, while delays and prolonged procedures increase the risk of complications.
Human ; Adolescent: 13-18 Yrs Old ; Child: 6-12 Yrs Old ; Foreign Bodies ; Endoscopy ; Child ; Retrospective Studies
3.The anesthetic management of a pediatric patient for drug-induced sleep endoscopy (DISE): A case report.
Acta Medica Philippina 2025;59(Early Access 2025):1-4
Drug-induced sleep endoscopy (DISE) is used for directly visualizing sites of obstruction among patients with obstructive sleep apnea (OSA). Owing to the scarcity of data, there is still no consensus on the anesthetic regimen for conducting pediatric DISE.
This paper presents a 5-year-old patient who underwent DISE using an opioid-sparing regimen with dexmedetomidine and propofol infusion.
Simultaneous dexmedetomidine and propofol infusion is a promising opioid-sparing regimen for pediatric DISE.
Human ; Male ; Child Preschool: 2-5 Yrs Old ; Endoscopy ; Propofol ; Dexmedetomidine ; Sleep Apnea, Obstructive
4.Attitudes of obstetrics and gynecology residents on laparoscopic skills training in a government training tertiary hospital
Lairah Mangondaya Untao ; Marie Janice Alcantara-Boquiren ; Paula Cynthia Cruz-Limlengco
Philippine Journal of Obstetrics and Gynecology 2025;49(1):10-17
OBJECTIVE
The aim of this study was to determine the different attitudes and perception of obstetrics and gynecology residents on laparoscopic skills training.
METHODSA cross-sectional research was conducted in a tertiary hospital’s Department of Obstetrics and Gynecology using a survey questionnaire. The respondents were resident physician trainees using population sampling. An approval to use the survey questionnaire from its developer was obtained. Descriptive statistics was used for analysis of the demographic profile. Pearson product moment correlation was used to determine correlation between expectancy-value constructs, simulation use and surgical experience.
RESULTSThe average hours the residents spent in simulation laparoscopic exercises was 11 h in the last 12 months and at least 1 h per week with supervision (76%). The reasons for using laparoscopic simulation include skill development (94%), proximity to the simulation lab (90%), free time (85%), recommendation of attending surgeon (84%), and requirement for rotation (84%). Among the expectant value constructs, only intrinsic interest utility value (r = −0.390) showed statistical correlation suggesting a weak negative correlation with simulation use. Hours of simulation use were significantly negatively correlated with self-efficacy for learning skills required to become proficient at minimally invasive surgery (MIS) (r = −0.390) and self-efficacy for learning sufficient MIS skills to perform procedures safely (r = −0.351).
CONCLUSIONSThe residents were motivated to do well and had greater self-belief and enjoyed performing and mastering the laparoscopic skills training. The residents’ perception revealed that there was an improvement in their MIS skills with the laparoscopic simulation exercises in the short time they spent in the simulation. Despite the residents’ positive attitude and perceptions, voluntary participation was limited. The most commonly cited barriers to the access of the surgical knowledge improvement laboratory and laparoscopy simulation unit were the lack of time due to the workload, conflicting schedules, and COVID-19 pandemic restrictions. Supervision of the residents is of great importance to provide guidance and motivation to the residents in improving their technical skills and performance in the operating room.
Human ; Minimally Invasive Surgery ; Minimally Invasive Surgical Procedures
5.Splenic abscess in the era of minimally invasive surgery: A case report on a 37-year-old male
Eric Jed A. Demecillo ; Geselita Maambong
Philippine Journal of Internal Medicine 2025;63(1):59-63
INTRODUCTION
Splenic Abscess is an ongoing infectious process with pus accumulation specifically at the spleen, this is associated with a high mortality rate with studies showing 16.6% among those diagnosed, with risk factors mainly present are among immunocompromised state. Among the immunocompetent population, an incidence of 0.14-0.70% were documented. 13 The etiology for this may include hematogenous or contiguous spread of infection as a pathophysiology, with bacterial seeding at the site. Detection of this is through ultrasound or CT scan, with a goal of identify a complex or a simple abscess. Therapeutics lie in choosing splenectomy, placing the patient in an immunocompromised state despite being at a young age against the conservative percutaneous drainage on top of the maximized antibiotic use. A recent meta-analysis showed a mortality rate of 12% among patients with splenectomy and a complication rate of 26%, however the percutaneous drainage had a mortality of 8% and a complication rate of 10% 14 This highlights the clinical awareness and decision among patients with splenic abscess.
CASEPresenting a case of 37-year-old female who came in with left upper quadrant pain. This patient had undergone laparoscopic cholecystectomy 6 months prior to admission with an unremarkable outcome. An onset of left upper quadrant pain was noted 3 months prior to admission and was initially conservatively managed with unrecalled antibiotics. Persistence of this prompted further work up where ultrasound revealed an abscess in the spleen and was then admitted for broad spectrum antibiotics, namely piperacillin-tazobactam and further imaging. CT scan of whole abdomen with contrast was then done which revealed splenomegaly with rim enhancing near fluid attenuating lesions in the mid to inferior pole. The complexity of the abscess prompted the decision for splenectomy, the gold standard for treatment for splenic abscess. Patient had tested negative for HIV.
CONCLUSIONSplenic abscess is a rare condition, usually presenting with fever and left upper quadrant pain, the patient however did not present with fever despite a complex abscess. Splenic abscess is associated with a high mortality rate. A wide array of differentials is considered in patients with left upper quadrant pain and laboratories are directed into investigating the structural cause for left upper quadrant pain as the spleen has many adjacent organs which may present similarly. The decision to choose splenectomy and percutaneous abscess determines survivability of infection as splenectomy places patient in an immunocompromised state, thus early recognition of splenic abscess, and feasibility of percutaneous drainage is vital to the out-hospital outcome for the patient. Among immunocompetent individuals, given the lower mortality and lower complication rates, it may be ideal to combine both medical and minimally invasive procedures and a rise in complication may then warrant splenectomy.
Human ; Bacteria ; Male ; Adult: 25-44 Yrs Old ; Splenectomy ; Minimally Invasive Surgery ; Minimally Invasive Surgical Procedures
6.Hybrid repair for complex thoracoabdominal and pararenal aortic aneurysms in high-risk patients: A case series.
Leoncio L. KAW JR. ; Tricia Angela G. SARILE ; Alduz S. CABASA ; Eduardo R. BAUTISTA
Acta Medica Philippina 2025;59(11):87-93
Repair of complex aortic aneurysms such as those involving the thoracoabdominal and pararenal aorta presents a formidable challenge for surgeons with significant perioperative morbidity and mortality. A hybrid procedure combining renovisceral debranching with endovascular aneurysm exclusion has been developed as an alternative approach for high-risk patients. This paper reports our initial experience with hybrid repair for these complex aortic diseases in three high-risk patients.
Human ; Male ; Aged: 65-79 Yrs Old ; Middle Aged: 45-64 Yrs Old ; Aorta ; Aortic Aneurysm ; Endovascular Procedures
7.Laparoscopic management of a parasitic mature cystic teratoma
John Paul Y. Reyes ; Chiaoling S. Sua-Lao
Philippine Journal of Reproductive Endocrinology and Infertility 2025;22(1):3-6
Parasitic dermoid cysts may form from autoamputation of the ovarian mass secondary to torsion or rupture. It may then reimplant in surrounding structures and undergo subsequent neovascularization and further growth. The true incidence of these cases is unknown, however, a study reported a 0.04% incidence among 1,007 cases of dermoid cysts. This report describes the case of a 30-year-old multigravida who presented with an ultrasound finding of an ovarian dermoid cyst, which, upon laparoscopic surgery, turned out to be a parasitic dermoid cyst adherent to the bladder, with grossly normal bilateral ovaries. Theories on the development of parasitic dermoid cyst are also presented.
Human
;
Female
;
Adult: 25-44 yrs old
;
dermoid cyst
;
laparoscopy
8.Timing of endoscopy and clinical outcomes in patients presenting with acute upper gastrointestinal bleeding in a tertiary hospital in Davao City, Philippines: A retrospective cohort study.
Cleo Christille Lynn G. LOM-OC ; Theresa Leona B. PRUDENCIO ; Karl Paolo O. DILLERA
Philippine Journal of Internal Medicine 2025;63(3):28-40
BACKGROUND
Upper gastrointestinal bleeding (UGIB) is a common cause of hospitalizations in adult Filipinos. Upper endoscopy is the cornerstone of diagnosis and therapy with guidelines recommending endoscopy within 24 hours of hospital admission. However, data on the clinical outcomes in relation to the optimal timing of endoscopy remains limited in Davao City.
METHODSA retrospective cohort study of adult patients (age ≥19) with a primary or secondary diagnosis of UGIB who underwent an upper endoscopy was conducted in a tertiary hospital in Davao City, Philippines from January 2019 to December 2022. Patient demographics and clinical data were analyzed by chart review. Patients were categorized based on the timing of endoscopy from admission or from the presentation of UGIB symptoms in patients previously admitted for other complaints: urgent (t ≤6 hours), early (t >6-24 hours), late (t >24-48 hours), and very late (t >48 hours). The 30-day all-cause in-hospital mortality, and the rates for further bleeding, endoscopic treatment, average units of blood transfused, intensive care unit admission, and duration of hospitalization within 30 days were compared. Statistical analyses were performed using the JASP software, and a P value < 0.05 was considered as statistically significant.
RESULTSA total of 142 patients were included in the study. Mean age was 62 years, with more males (66.2%) than females (33.8%). Non-variceal causes, particularly erosive diseases (53.7%), were the most common endoscopy findings in our center. Endoscopic treatments were only performed in 26 patients (18.3%). The 30-day all-cause in-hospital mortality rate did not differ between the urgent, early, late and very late elective endoscopy groups (25% vs 2.6% vs 9.3% vs 13%; p=0.26). Although it did not reach statistical significance, urgent timing (n=4) was associated with a higher further bleeding rate (25%), and the need for endoscopic intervention (50%). A significant association between early and late endoscopy groups in the duration of hospitalization of only one week was demonstrated (p=0.032). There was no difference regarding the rate of ICU admissions and mean number of blood transfused among the four groups.
CONCLUSIONThere were no significant differences in mortality and other clinical outcomes between all four endoscopy groups except for the duration of hospitalization. Among admitted UGIB patients, optimal medical management is still emphasized and elective endoscopy within 24 hours or until the patient is stabilized can be safely performed in most acute UGIB patients.
Human ; Endoscopy


Result Analysis
Print
Save
E-mail