1.A smart device application for acute pain service in surgical patients at a tertiary hospital in South Korea: a prospective observational feasibility study
Soo-Hyuk YOON ; Susie YOON ; Da Som JEONG ; Minah LEE ; Eunju LEE ; Young Jae CHO ; Ho-Jin LEE
Anesthesia and Pain Medicine 2024;19(3):216-226
		                        		
		                        			 Background:
		                        			Pain assessment and patient education are essential for successful postoperative pain management. However, the provision of personnel for performing these tasks is often insufficient. Recently, attempts have been made to implement smartphone applications for educating and monitoring surgical patients. We developed a smartphone application (app) for postoperative pain management, and conducted a feasibility study. 
		                        		
		                        			Methods:
		                        			This single-center prospective observational study included 60 patients aged < 70 years who underwent elective surgery. This study evaluated the SmartAPS application, which offers tools for postoperative pain assessment and educational materials for pain management. The primary outcome was the active usage rate, defined as responding at least twice daily on postoperative days (PODs) 1 and 2. Additionally, we investigated patient satisfaction with the app and educational videos as well as any challenges encountered during use. 
		                        		
		                        			Results:
		                        			Sixty patients were enrolled in the study and active app use was achieved in 56.7% of them. Response rates peaked at 85.0% for pain intensity and 83.3% for opioid-related side effects at 14:00 on POD 1 but dropped to 56.7% and 58.3%, respectively, at 18:00 on POD 2. Among the patients who responded to the survey regarding the app usage, 84.0% reported satisfaction with the app and 80% found it beneficial for managing postoperative pain. Furthermore, 92.0% did not encounter difficulties using the app, indicating a generally positive user experience. 
		                        		
		                        			Conclusions
		                        			Our findings support the utility of the SmartAPS application in acute pain services, highlighting its potential for improving postoperative pain management. 
		                        		
		                        		
		                        		
		                        	
2.A smart device application for acute pain service in surgical patients at a tertiary hospital in South Korea: a prospective observational feasibility study
Soo-Hyuk YOON ; Susie YOON ; Da Som JEONG ; Minah LEE ; Eunju LEE ; Young Jae CHO ; Ho-Jin LEE
Anesthesia and Pain Medicine 2024;19(3):216-226
		                        		
		                        			 Background:
		                        			Pain assessment and patient education are essential for successful postoperative pain management. However, the provision of personnel for performing these tasks is often insufficient. Recently, attempts have been made to implement smartphone applications for educating and monitoring surgical patients. We developed a smartphone application (app) for postoperative pain management, and conducted a feasibility study. 
		                        		
		                        			Methods:
		                        			This single-center prospective observational study included 60 patients aged < 70 years who underwent elective surgery. This study evaluated the SmartAPS application, which offers tools for postoperative pain assessment and educational materials for pain management. The primary outcome was the active usage rate, defined as responding at least twice daily on postoperative days (PODs) 1 and 2. Additionally, we investigated patient satisfaction with the app and educational videos as well as any challenges encountered during use. 
		                        		
		                        			Results:
		                        			Sixty patients were enrolled in the study and active app use was achieved in 56.7% of them. Response rates peaked at 85.0% for pain intensity and 83.3% for opioid-related side effects at 14:00 on POD 1 but dropped to 56.7% and 58.3%, respectively, at 18:00 on POD 2. Among the patients who responded to the survey regarding the app usage, 84.0% reported satisfaction with the app and 80% found it beneficial for managing postoperative pain. Furthermore, 92.0% did not encounter difficulties using the app, indicating a generally positive user experience. 
		                        		
		                        			Conclusions
		                        			Our findings support the utility of the SmartAPS application in acute pain services, highlighting its potential for improving postoperative pain management. 
		                        		
		                        		
		                        		
		                        	
3.A smart device application for acute pain service in surgical patients at a tertiary hospital in South Korea: a prospective observational feasibility study
Soo-Hyuk YOON ; Susie YOON ; Da Som JEONG ; Minah LEE ; Eunju LEE ; Young Jae CHO ; Ho-Jin LEE
Anesthesia and Pain Medicine 2024;19(3):216-226
		                        		
		                        			 Background:
		                        			Pain assessment and patient education are essential for successful postoperative pain management. However, the provision of personnel for performing these tasks is often insufficient. Recently, attempts have been made to implement smartphone applications for educating and monitoring surgical patients. We developed a smartphone application (app) for postoperative pain management, and conducted a feasibility study. 
		                        		
		                        			Methods:
		                        			This single-center prospective observational study included 60 patients aged < 70 years who underwent elective surgery. This study evaluated the SmartAPS application, which offers tools for postoperative pain assessment and educational materials for pain management. The primary outcome was the active usage rate, defined as responding at least twice daily on postoperative days (PODs) 1 and 2. Additionally, we investigated patient satisfaction with the app and educational videos as well as any challenges encountered during use. 
		                        		
		                        			Results:
		                        			Sixty patients were enrolled in the study and active app use was achieved in 56.7% of them. Response rates peaked at 85.0% for pain intensity and 83.3% for opioid-related side effects at 14:00 on POD 1 but dropped to 56.7% and 58.3%, respectively, at 18:00 on POD 2. Among the patients who responded to the survey regarding the app usage, 84.0% reported satisfaction with the app and 80% found it beneficial for managing postoperative pain. Furthermore, 92.0% did not encounter difficulties using the app, indicating a generally positive user experience. 
		                        		
		                        			Conclusions
		                        			Our findings support the utility of the SmartAPS application in acute pain services, highlighting its potential for improving postoperative pain management. 
		                        		
		                        		
		                        		
		                        	
4.A smart device application for acute pain service in surgical patients at a tertiary hospital in South Korea: a prospective observational feasibility study
Soo-Hyuk YOON ; Susie YOON ; Da Som JEONG ; Minah LEE ; Eunju LEE ; Young Jae CHO ; Ho-Jin LEE
Anesthesia and Pain Medicine 2024;19(3):216-226
		                        		
		                        			 Background:
		                        			Pain assessment and patient education are essential for successful postoperative pain management. However, the provision of personnel for performing these tasks is often insufficient. Recently, attempts have been made to implement smartphone applications for educating and monitoring surgical patients. We developed a smartphone application (app) for postoperative pain management, and conducted a feasibility study. 
		                        		
		                        			Methods:
		                        			This single-center prospective observational study included 60 patients aged < 70 years who underwent elective surgery. This study evaluated the SmartAPS application, which offers tools for postoperative pain assessment and educational materials for pain management. The primary outcome was the active usage rate, defined as responding at least twice daily on postoperative days (PODs) 1 and 2. Additionally, we investigated patient satisfaction with the app and educational videos as well as any challenges encountered during use. 
		                        		
		                        			Results:
		                        			Sixty patients were enrolled in the study and active app use was achieved in 56.7% of them. Response rates peaked at 85.0% for pain intensity and 83.3% for opioid-related side effects at 14:00 on POD 1 but dropped to 56.7% and 58.3%, respectively, at 18:00 on POD 2. Among the patients who responded to the survey regarding the app usage, 84.0% reported satisfaction with the app and 80% found it beneficial for managing postoperative pain. Furthermore, 92.0% did not encounter difficulties using the app, indicating a generally positive user experience. 
		                        		
		                        			Conclusions
		                        			Our findings support the utility of the SmartAPS application in acute pain services, highlighting its potential for improving postoperative pain management. 
		                        		
		                        		
		                        		
		                        	
5.A smart device application for acute pain service in surgical patients at a tertiary hospital in South Korea: a prospective observational feasibility study
Soo-Hyuk YOON ; Susie YOON ; Da Som JEONG ; Minah LEE ; Eunju LEE ; Young Jae CHO ; Ho-Jin LEE
Anesthesia and Pain Medicine 2024;19(3):216-226
		                        		
		                        			 Background:
		                        			Pain assessment and patient education are essential for successful postoperative pain management. However, the provision of personnel for performing these tasks is often insufficient. Recently, attempts have been made to implement smartphone applications for educating and monitoring surgical patients. We developed a smartphone application (app) for postoperative pain management, and conducted a feasibility study. 
		                        		
		                        			Methods:
		                        			This single-center prospective observational study included 60 patients aged < 70 years who underwent elective surgery. This study evaluated the SmartAPS application, which offers tools for postoperative pain assessment and educational materials for pain management. The primary outcome was the active usage rate, defined as responding at least twice daily on postoperative days (PODs) 1 and 2. Additionally, we investigated patient satisfaction with the app and educational videos as well as any challenges encountered during use. 
		                        		
		                        			Results:
		                        			Sixty patients were enrolled in the study and active app use was achieved in 56.7% of them. Response rates peaked at 85.0% for pain intensity and 83.3% for opioid-related side effects at 14:00 on POD 1 but dropped to 56.7% and 58.3%, respectively, at 18:00 on POD 2. Among the patients who responded to the survey regarding the app usage, 84.0% reported satisfaction with the app and 80% found it beneficial for managing postoperative pain. Furthermore, 92.0% did not encounter difficulties using the app, indicating a generally positive user experience. 
		                        		
		                        			Conclusions
		                        			Our findings support the utility of the SmartAPS application in acute pain services, highlighting its potential for improving postoperative pain management. 
		                        		
		                        		
		                        		
		                        	
6.The Effects of Acute Stress on Evoked-cortical Connectivity through Wide-field Optical Mapping of Neural and Hemodynamic Signals
Hayeon KIM ; Haebin JEONG ; Jiyoung LEE ; Jaeseung YEI ; Minah SUH
Experimental Neurobiology 2024;33(3):140-151
		                        		
		                        			
		                        			 A single exposure to stress can induce functional changes in neurons, potentially leading to acute stress disorder or post-traumatic stress disorder.In this study, we used in vivo wide-field optical mapping to simultaneously measure neural calcium signals and hemodynamic responses over the whole cortical area. We found that cortical mapping to whisker stimuli was altered under acute stress conditions. In particular, callosal projections in the anterior cortex (primary/secondary motor, somatosensory forelimb cortex) relative to barrel field (S1BF) of somatosensory cortex were weakened. On the contrary, the projections in posterior cortex relative to S1BF were mostly unchanged or were only occasionally strengthened. In addition, changes in intra-cortical connection were opposite to those in inter-cortical connection. Thus, the S1BF connections to the anterior cortex were strengthened while those to the posterior cortex were weakened. This suggests that the well-known barrel cortex projection route was enhanced. In summary, our in vivo wide-field optical mapping study indicates that a single acute stress can impact whole-brain networks, affecting both neural and hemodynamic responses. 
		                        		
		                        		
		                        		
		                        	
7.Operational Status and Evidence Assessment of Community Mental Health Programs in Korea
Seung-Hee AHN ; Jee Hoon SOHN ; Hwo-Yeon SEO ; Hae Woo LEE ; Seongju JO ; Soung-Nam KIM ; Hye-Young MIN ; Minah SOH ; Se Young YOO ; Sung Joon CHO ; Jee Eun PARK
Journal of Korean Neuropsychiatric Association 2024;63(2):116-131
		                        		
		                        			 Objectives:
		                        			This study analyzed the current state of community mental health programs in Korea to develop evidence-based criteria for these programs. 
		                        		
		                        			Methods:
		                        			Seventy community mental health facilities nationwide were surveyed about the scope of their operated mental health programs. Details, including program structure, staff expertise, standardization, and quality management, of the 511 programs submitted by the facilities as their representative programs were also analyzed to evaluate their efforts for evidence-based practice. 
		                        		
		                        			Results:
		                        			The average number of programs operated by community mental health welfare centers was 15.9. The most common programs were those related to serious mental illness (SMI), followed by child/adolescent mental health programs, early psychosis programs, and non-SMI adult mental health programs. In the case of community addiction management centers, there were 7.2 different addiction-related programs per center. Among the psychiatric rehabilitation facilities for SMI, the average number of programs for SMI was 13.1, with some programs for early psychosis. Of the 511 programs submitted as representative programs in their facilities, only 12.3% were judged to be good evidence-based programs. 
		                        		
		                        			Conclusion
		                        			More efforts by mental health professionals and governments are needed to implement evidence-based programs in Korea. 
		                        		
		                        		
		                        		
		                        	
8.A Case of Elastofibroma on the Neck
Sehoon LEE ; Suyeun KIM ; Minah CHO ; Yu Jin HAN ; Yu Ri WOO ; Sang Hyun CHO ; Jeong Deuk LEE ; Hei Sung KIM
Korean Journal of Dermatology 2024;62(7):432-434
		                        		
		                        		
		                        		
		                        	
9.Efficacy and Safety of Lurasidone vs. Quetiapine XR in Acutely Psychotic Patients With Schizophrenia in Korea: A Randomized, Double-Blind, Active-Controlled Trial
Se Hyun KIM ; Do-Un JUNG ; Do Hoon KIM ; Jung Sik LEE ; Kyoung-Uk LEE ; Seunghee WON ; Bong Ju LEE ; Sung-Gon KIM ; Sungwon ROH ; Jong-Ik PARK ; Minah KIM ; Sung Won JUNG ; Hong Seok OH ; Han-yong JUNG ; Sang Hoon KIM ; Hyun Seung CHEE ; Jong-Woo PAIK ; Kyu Young LEE ; Soo In KIM ; Seung-Hwan LEE ; Eun-Jin CHEON ; Hye-Geum KIM ; Heon-Jeong LEE ; In Won CHUNG ; Joonho CHOI ; Min-Hyuk KIM ; Seong-Jin CHO ; HyunChul YOUN ; Jhin-Goo CHANG ; Hoo Rim SONG ; Euitae KIM ; Won-Hyoung KIM ; Chul Eung KIM ; Doo-Heum PARK ; Byung-Ook LEE ; Jungsun LEE ; Seung-Yup LEE ; Nuree KANG ; Hee Yeon JUNG
Psychiatry Investigation 2024;21(7):762-771
		                        		
		                        			 Objective:
		                        			This study was performed to evaluate the efficacy and safety of lurasidone (160 mg/day) compared to quetiapine XR (QXR; 600 mg/day) in the treatment of acutely psychotic patients with schizophrenia. 
		                        		
		                        			Methods:
		                        			Patients were randomly assigned to 6 weeks of double-blind treatment with lurasidone 160 mg/day (n=105) or QXR 600 mg/day (n=105). Primary efficacy measure was the change from baseline to week 6 in Positive and Negative Syndrome Scale (PANSS) total score and Clinical Global Impressions severity (CGI-S) score. Adverse events, body measurements, and laboratory parameters were assessed. 
		                        		
		                        			Results:
		                        			Lurasidone demonstrated non-inferiority to QXR on the PANSS total score. Adjusted mean±standard error change at week 6 on the PANSS total score was -26.42±2.02 and -27.33±2.01 in the lurasidone and QXR group, respectively. The mean difference score was -0.91 (95% confidence interval -6.35–4.53). The lurasidone group showed a greater reduction in PANSS total and negative subscale on week 1 and a greater reduction in end-point CGI-S score compared to the QXR group. Body weight, body mass index, and waist circumference in the lurasidone group were reduced, with significantly lower mean change compared to QXR. Endpoint changes in glucose, cholesterol, triglycerides, and low-density lipoprotein levels were also significantly lower. The most common adverse drug reactions with lurasidone were akathisia and nausea. 
		                        		
		                        			Conclusion
		                        			Lurasidone 160 mg/day was found to be non-inferior to QXR 600 mg/day in the treatment of schizophrenia with comparable efficacy and tolerability. Adverse effects of lurasidone were generally tolerable, and beneficial effects on metabolic parameters can be expected. 
		                        		
		                        		
		                        		
		                        	
10.Effects of Long-acting Injectable 3-Monthly Paliperidone Palmitate on the Clinical and Social Performance of Patients with Schizophrenia
Jihoon OH ; Jihye OH ; Dong Wook KIM ; HyunChul YOUN ; Sae-Hoon KIM ; Soo In KIM ; In Won CHUNG ; Kuan Shu WANG ; Minah KIM ; Jong-Woo PAIK ; Min Jung KOH ; Yoosun LEE ; Seok Young CHOI ; Jung-Jin KIM
Clinical Psychopharmacology and Neuroscience 2023;21(1):126-134
		                        		
		                        			 Objective:
		                        			To investigate the effects of long-acting injectable 3-monthly paliperidone palmitate on the clinical and social functioning of patients with schizophrenia. 
		                        		
		                        			Methods:
		                        			This study enrolled patients with schizophrenia receiving long-acting injectable 1-monthly paliperidone palmitate for at least 4 months and who subsequently received 3-monthly paliperidone palmitate. Accordingly, 418 patients were followed up for 24 weeks. Their clinical symptoms and social functioning were measured using the Clinical Global Impression-Severity of Illness and Personal and Social Performance scales. 
		                        		
		                        			Results:
		                        			The Personal and Social Performance total score was significantly higher after 3-monthly paliperidone palmitate treatment than at baseline (baseline vs. week 24: 54.3 ± 18.0 vs. 61.0 ± 14.5 [mean ± standard deviation]; p < 0.001; Wilcoxon signed-rank test); the proportion of patients in the mildly ill group (scores 71−100) also increased significantly (baseline vs. week 24: 16.5% vs. 20.6%; p< 0.001; McNemar-Bowker test). The mean Clinical Global Impression-Severity of Illness score decreased significantly (baseline vs. week 24: 3.7 ± 1.0 vs. 3.4 ± 0.9; p< 0.001; Wilcoxon signed-rank test), as did the proportion of patients in the severely ill group (baseline vs. week 24: 4.1% vs. 2.1%; p < 0.001; McNemar-Bowker test). 
		                        		
		                        			Conclusion
		                        			Continuous 3-monthly paliperidone palmitate treatment significantly enhances the personal and social performance of patients with schizophrenia and reduces the proportion of those with severe illness. These findings suggest that long-acting injectable antipsychotic administration at intervals longer than 1 month might improve the social functioning of and promote return to activities of daily living in patients with schizophrenia. 
		                        		
		                        		
		                        		
		                        	
            
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