1.Correlation between preoperative sleep disorders and postoperative delayed neurocognitive recovery in elderly patients.
Renhua LI ; Na CHEN ; E WANG ; Zhaohui TANG
Journal of Central South University(Medical Sciences) 2021;46(11):1251-1259
		                        		
		                        			OBJECTIVES:
		                        			Perioperative neurocognitive disorders (PND) is one of the important factors affecting the recovery of the elderly after surgery, and sleep disorders are also one of the common diseases of the elderly. Previous studies have shown that the quality of postoperative sleep may be factor affecting postoperative cognitive function, but there are few studies on the relationship between preoperative sleep disorders and postoperative cognitive dysfunction. This study aims to explore the relationship between preoperative sleep disorders and postoperative delayed neurocognitive recovery in elderly patients, and provide references for improving the prognosis and quality of life of patients.
		                        		
		                        			METHODS:
		                        			This study was porformed as a prospective cohort study. Elderly patients (age≥65 years old) underwent elective non-cardiac surgery at Xiangya Hospital of Central South University from October 2019 to January 2020 were selected and interviewed 1 day before the operation. The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment Scale (MoCA) were used to assess the patient's baseline cognitive status. Patients with preoperative MMSE scores of less than 24 points were excluded. For patients meeting the criteria of inclusion, Pittsburgh Sleep Quality Index (PSQI) scale was used to evaluate the patients, and the patients were divided into a sleep disorder group and a non-sleep disorder group according to the score. General data of patients were collected and intraoperative data were recorded, such as duration of surgery, anesthetic time, surgical site, intraoperative fluid input, intraoperative blood product input, intraoperative blood loss and drug use. On consecutive 5 days after surgery, Numerical Rating Scale (NRS) was used to evaluate the sleep of the previous night and the pain of the day, which were recorded as sleep NRS score and pain NRS score; Confusion Assessment Method for ICU (CAM-ICU) scale and Confusion Assessment Method (CAM) scale were used to assess the occurrence of delirium. On the 7th day after the operation, the MMSE and MoCA scales were used to evaluate cognitive function of patients. We compared the incidence of postoperative complications, the number of deaths, the number of unplanned ICU patients, the number of unplanned secondary operations, etc between the 2 groups. The baseline and prognosis of the 2 groups of patients were analyzed by univariate and multivariate logistics to analyze their correlation.
		                        		
		                        			RESULTS:
		                        			A total of 105 patients were collected in this study, including 32 patients in the sleep disorder group and 73 patients in the non-sleep disorder group. The general information of the 2 groups, such as age, gender, body mass index, and surgery site, were not statistically significant (all 
		                        		
		                        			CONCLUSIONS
		                        			Preoperative sleep disorders can increase the risk of delayed neurocognitive function recovery in elderly patients. Active treatment of preoperative sleep disorders may improve perioperative neurocognitive function in elderly patients.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mental Status and Dementia Tests
		                        			;
		                        		
		                        			Postoperative Complications/epidemiology*
		                        			;
		                        		
		                        			Prospective Studies
		                        			;
		                        		
		                        			Quality of Life
		                        			;
		                        		
		                        			Sleep Quality
		                        			;
		                        		
		                        			Sleep Wake Disorders/etiology*
		                        			
		                        		
		                        	
2.Impulse Control and ERP Characteristics of Patients with Mental Disorder Caused by Traumatic Brain Injury.
Hong Fei SONG ; Xi DENG ; Ning YANG ; Bo HAO ; Yu Bo HU ; Yan Wei SHI ; Li XUE ; Hu ZHAO
Journal of Forensic Medicine 2020;36(3):326-332
		                        		
		                        			
		                        			Objective To explore the impulse control and event-related potential (ERP) characteristics of patients with mental disorders caused by traumatic brain injury (TBI) in forensic psychiatry identification and to provide objective auxiliary indicators for forensic psychiatry identification. Methods Thirty patients (TBI group) with mental disorders caused by traumatic brain injury, who were identified as mild psychiatric impairment by judicial psychiatry, including 24 males and 6 females, as well as the thirty people in the control group participated in the study. All the participants completed Barratt Impulsiveness Scale-11 (BIS-11) and ERP induced by Go/NoGo tasks. BIS-11 and ERP data were collected and analyzed. Results The results of the BIS-11 showed that the total score and subscale scores of the TBI group were higher compared to the control group (P<0.05). Moreover, the TBI group exhibited significantly lower NoGo-N2 amplitude and lower NoGo-P3 amplitude than the control group. The NoGo-N2 amplitude was larger than the Go-N2 amplitude, and the NoGo-P3 amplitude was larger than the Go-P3 amplitude in both groups (P<0.05). Conclusion Traumatic brain injury could impair impulse control of mild psychiatric impairment patients, and the amplitudes of NoGo-N2 and NoGo-P3 could be important parameters to evaluate the impulse control of patients with mental disorders caused by traumatic brain injury.
		                        		
		                        		
		                        		
		                        			Brain Injuries, Traumatic/complications*
		                        			;
		                        		
		                        			Electroencephalography
		                        			;
		                        		
		                        			Evoked Potentials
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Inhibition, Psychological
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Mental Disorders/physiopathology*
		                        			;
		                        		
		                        			Neuropsychological Tests
		                        			;
		                        		
		                        			Reaction Time
		                        			
		                        		
		                        	
3.Risk profiling in patients undergoing penile prosthesis implantation.
Linda M HUYNH ; Mohamad M OSMAN ; Faysal A YAFI
Asian Journal of Andrology 2020;22(1):8-14
		                        		
		                        			
		                        			Penile prosthesis implantation is the gold standard of surgical therapy for patients with medication-refractory erectile dysfunction. However, this umbrella definition includes significant heterogeneity and associated risk profiles that should be candidly discussed and addressed perioperatively. Factors associated with operative success and patient satisfaction are often surgery specific; however, risk profiling via patient selection, preoperative optimization, proper device selection, and intraoperative consideration are highly correlated. Some examples of common risk profiles include comorbidity(ies) such as cardiovascular disease, diabetes mellitus, prior abdominal surgery, Peyronie's disease, and psychological risk factors. Similarly, integration of surgeon- and patient-amenable characteristics is key to decreasing risk of infection, complication, and need for revision. Finally, patient risk profiling provides a unique context for proper device selection and evidence-based intraoperative considerations.
		                        		
		                        		
		                        		
		                        			Cardiovascular Diseases/epidemiology*
		                        			;
		                        		
		                        			Comorbidity
		                        			;
		                        		
		                        			Diabetes Mellitus/epidemiology*
		                        			;
		                        		
		                        			Erectile Dysfunction/surgery*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Mental Disorders/epidemiology*
		                        			;
		                        		
		                        			Patient Satisfaction
		                        			;
		                        		
		                        			Patient Selection
		                        			;
		                        		
		                        			Penile Implantation/methods*
		                        			;
		                        		
		                        			Penile Induration/epidemiology*
		                        			;
		                        		
		                        			Penile Prosthesis
		                        			;
		                        		
		                        			Postoperative Complications/prevention & control*
		                        			;
		                        		
		                        			Prosthesis-Related Infections/prevention & control*
		                        			;
		                        		
		                        			Reoperation
		                        			;
		                        		
		                        			Risk Assessment
		                        			;
		                        		
		                        			Surgical Wound Infection/prevention & control*
		                        			
		                        		
		                        	
4.Application of Mismatch Negative in Evaluation of Severity of Mental Disorders due to Traumatic Brain Injury.
Hao Zhe LI ; Lu LIU ; Sheng Yu ZHANG ; Chen CHEN ; Chao LIU ; Hui Yu FAN ; Yan XING ; Jing DAI ; Qin Ting ZHANG ; Wei Xiong CAI
Journal of Forensic Medicine 2019;35(6):695-700
		                        		
		                        			
		                        			Objective To explore the applied value of mismatch negative (MMN) in evaluation of severity of mental disorders due to traumatic brain injury. Methods Thirty-five patients(case group) that conform to the diagnostic criteria of organic (traumatic brain injury) mental disorder in ICD-10 Classification of Mental and Behavioural Disorders criteria were selected. Twenty-four healthy subjects (normal control group) that matched the case group in terms of gender, age composition ratio and educational level were selected. All subjects were evaluated by Activity of Daily Living Scale (ADL) and Social Disability Screening Schedule (SDSS) and then examined by Event-Related Potential (ERP). A statistical analysis of the data was made by SPSS 22.0 software. Results The 32 patients and 24 normal control subjects completed the study. The scores of ADL and SDSS were significantly higher in the case group than in the normal control group (P<0.05). The latency of Fz, FCz, Cz and Pz in the case group was significantly longer than that in the normal control group (P<0.05). In the case group, the latency of Fz, FCz, Cz and Pz was positively correlated with the scores of ADL and SDSS (P<0.05). The equation can be well fitted with the scores of ADL and SDSS. The latency and amplitude of Fz, FCz, Cz and Pz were used as concomitant variables and whether or not the subjects had mental disorders due to traumatic brain injury as dependent variables. Conclusion The latency of MMN can be used as an indicator in potential evaluation of the severity of mental disorders due to traumatic brain injury, which means that the longer the latency of MMN is, the more severe mental disorders due to traumatic brain injury may be. The combined application of ADL, SDSS and MMN can be an objective indicator in preliminary judgment of mental disorders due to traumatic brain injury.
		                        		
		                        		
		                        		
		                        			Activities of Daily Living
		                        			;
		                        		
		                        			Brain Injuries, Traumatic/complications*
		                        			;
		                        		
		                        			Disabled Persons
		                        			;
		                        		
		                        			Evoked Potentials
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mental Disorders/etiology*
		                        			;
		                        		
		                        			Software
		                        			;
		                        		
		                        			Trauma Severity Indices
		                        			
		                        		
		                        	
5.Impact of the neglected Cysticercus cellulose infection on mental health among school-aged children in Tibetan agricultural areas.
Ruixue YE ; Yuju WU ; Qingzhi WANG ; Min CAO ; Tiaoying LI ; Xingwang CHEN ; Huan ZHOU
Journal of Central South University(Medical Sciences) 2018;43(10):1137-1144
		                        		
		                        			
		                        			To determine the impact of Cysticercus cellulose (C. cellulose) infection on mental health among school-aged children in Tibetan agricultural areas of Sichuan Province.
 Methods: In October 2015, all primary schools located in Tibetan agricultural areas in Yajiang, Ruoergai, and Muli county of Sichuan Province were selected as the research sites. All school-aged children at five- and six-grade were enrolled for the study by a multistage stratified cluster sampling method. Antibodies against C. cellulose were detected. Mental Health Test and questionnaire survey were conducted for school-aged children to collect data. The impact of C. cellulose infection on mental health among school-aged children was analyzed with the multilevel linear regression.
 Results: A total of 2 453 school-aged children were investigated. The C. cellulose seropositive rate was 6.03% (148/2 453). There were 0.16% (4/2 453) patients with seropositive accompanied by seizure, 2.28% (56/2 453) with seropositive accompanied by headache, 2.08% (51/2 453) with seropositive accompanied by frequent weak, and 0.41% (10/2 453) were seropositive accompanied by frequent nausea. The rate of C. cellulose infection was 4.53% (111/2 453). The mean score of the mental health test was 6.59±2.61. There were significant difference in score of mental health test in children whose demographic characteristics were different. The mental health scores of school-aged children were clustered at the school level. After controlling the factors of demographic characteristics, the result of multilevel model demonstrated that the factor of school-aged children with C. cellulose seropositive accompanied by headache was statistically significant (β=1.14, P=0.017).
 Conclusion: The status of C. cellulose infection among school-aged children in Tibetan agricultural areas is not optimistic. C. cellulose infection has impacted on mental health of local school-aged children. It is necessary to strengthen the prevention and control of C. cellulose infection in epidemic area.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Cysticercosis
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			epidemiology
		                        			;
		                        		
		                        			Cysticercus
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mental Health
		                        			;
		                        		
		                        			Neurodevelopmental Disorders
		                        			;
		                        		
		                        			epidemiology
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Seroepidemiologic Studies
		                        			;
		                        		
		                        			Tibet
		                        			;
		                        		
		                        			epidemiology
		                        			
		                        		
		                        	
6.Increased Risk of Psychiatric Disorders in Women with Polycystic Ovary Syndrome in Southwest China.
Jing TAN ; Qiu-Yi WANG ; Gui-Mei FENG ; Xue-Ying LI ; Wei HUANG ;
Chinese Medical Journal 2017;130(3):262-266
BACKGROUNDPolycystic ovary syndrome (PCOS) and its characteristic symptoms have been associated with physical and psychological issues in women of reproductive age. The current study was conducted in response to the dearth of systematic research related to psychological functioning and quality of life in patients with PCOS in Southwest China, and to determine whether patients with PCOS exhibit poorer mental health (MH) compared to healthy women of the same age and living in the same region, without a PCOS diagnosis.
METHODSWe enrolled 120 outpatients with PCOS and 100 healthy controls in this study. Standardized questionnaires were administered to assess general MH conditions (General Health Questionnaire-12-item version), anxiety (State-Trait Anxiety Inventory), depression (Beck Depression Inventory), as well as health-related quality of life (HRQoL) measured using the 36-item short-form health survey. The independent samples t-test was conducted for continuous study variables. For categorical variables, the Pearson Chi-square test, Fisher's exact test, and logistic regression were performed.
RESULTSThe prevalence of anxiety (13.3% vs. 2.0%) and depression (27.5% vs. 3.0%) was higher in patients with PCOS compared to the controls (both P< 0.05). Patients with PCOS had decreased HRQoL. Patients with PCOS who had fertility requirements were more likely to be anxious and depressed than those without fertility requirements (anxiety: 22.6% [12/53] vs. 5.9% [4/67], χ2 = 7.117, P = 0.008; depression: 37.7% (20/53) vs.19.4% (13/67), χ2 = 4.988, P = 0.026).
CONCLUSIONSPCOS and related symptoms may be risk factors for depression and anxiety. Professionals should be concerned with the MH of women with PCOS, and psychological therapy should be considered.
Adult ; Anxiety ; diagnosis ; etiology ; China ; Depression ; diagnosis ; etiology ; Female ; Humans ; Mental Disorders ; diagnosis ; etiology ; Polycystic Ovary Syndrome ; complications ; physiopathology ; psychology ; Psychiatric Status Rating Scales ; Quality of Life ; Surveys and Questionnaires ; Young Adult
7.Isolated 9p Duplication With der(Y)t(Y;9)(q12;p13.2) in a Male Patient With Cardiac Defect and Mental Retardation Confirmed by Chromosomal Microarray.
Moonhee OH ; In Jeong CHO ; Saeam SHIN ; Seung Tae LEE ; Jong Rak CHOI
Annals of Laboratory Medicine 2016;36(2):191-193
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Brain/diagnostic imaging
		                        			;
		                        		
		                        			Bronchoscopy
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		                        			*Chromosomes, Human, Pair 9
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		                        			Death, Sudden, Cardiac/*etiology
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		                        			Gene Duplication
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		                        			Humans
		                        			;
		                        		
		                        			Karyotyping
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		                        			Male
		                        			;
		                        		
		                        			Mental Disorders/*complications/genetics/pathology
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Tracheomalacia/diagnostic imaging
		                        			;
		                        		
		                        			Ventricular Fibrillation/complications
		                        			
		                        		
		                        	
8.Distribution and Risk Factors of Disability Attributed to Personality Disorders: A National Cross-sectional Survey in China.
Ting-Ting ZHANG ; Yue-Qin HUANG ; Zhao-Rui LIU ; Hong-Guang CHEN
Chinese Medical Journal 2016;129(15):1765-1771
BACKGROUNDPersonality disorders can lead to some disability. However, little is known about the disability prevalence and function impairments. This study aimed to describe the disability prevalence attributed to personality disorders, its distribution, impairments of daily activities and social functions, and risk factors in China.
METHODSUsing a descriptive and analytic epidemiological method, data from the Second China National Sample Survey on Disability in 2006 were analyzed. The disability prevalence attributed to personality disorders, its distribution in different people and regions, and risk factors were statistically calculated.
RESULTSRespondents included 1,909,205 adults. The disability prevalence rate attributed to personality disorders in China was 5.9/100,000. The disability rate attributed to personality disorders of males was higher than that of females (P = 0.012), while the rate of the unemployed was higher than that of the employed (P < 0.001). Furthermore, the rates of unmarried/divorced/widowed people and the illiterate population were higher than those of married and educated people (P < 0.001). Regarding the severity of disability attributable to personality disorders, mild disability accounted for a majority or 60% of the respondents. The data showed that disability mainly impaired respondents' ability to engage in daily activities, get along with people, and participate in social situations. According to the case-control study, marriage, employment, and higher education were protective factors of disability.
CONCLUSIONSThe prevalence of disability attributed to personality disorders is low in China and always leads to mild disability. The distribution of disability attributed to personality disorders also varies in the Chinese population.
Adult ; Age Distribution ; China ; epidemiology ; Cross-Sectional Studies ; Disabled Persons ; statistics & numerical data ; Female ; Humans ; Male ; Mental Disorders ; epidemiology ; etiology ; Middle Aged ; Personality Disorders ; complications ; epidemiology ; Risk Factors
9.A Case of Aerophagia Diagnosed by Multichannel Intraluminal Impedance Monitoring.
Ki Chang SOHN ; Young Hoon JEONG ; Dong Ho JO ; Won Gak HEO ; Dong Han YEOM ; Suck Chei CHOI ; Han Seung RYU
The Korean Journal of Gastroenterology 2015;66(5):282-285
		                        		
		                        			
		                        			Aerophagia is a disorder caused by abnormal accumulation of air in the gastrointestinal tract as a result of repetitive and frequent inflow of air through the mouth. For the diagnosis of this condition, it is difficult to objectively measure the air swallowing. However, multichannel intraluminal impedance monitoring facilitates the differential diagnosis between normal air swallowing and pathologic aerophagia, and can aid in the determination of the frequency and amount of air swallowed. In this report, in addition to a literature review, we describe a case of 36-year-old man with abdominal distension who was diagnosed with aerophagia using esophageal impedance monitoring and was treated with clonazepam.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aerophagy/*diagnosis/diagnostic imaging/drug therapy
		                        			;
		                        		
		                        			Anticonvulsants/therapeutic use
		                        			;
		                        		
		                        			Clonazepam/therapeutic use
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Electric Impedance
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Mental Disorders/complications
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
10.Blast-induced traumatic brain injury: a new trend of blast injury research.
Chinese Journal of Traumatology 2015;18(4):201-203
		                        		
		                        			
		                        			Blast injury has become the major life- and function-threatening injuries in recent warfares. There is increased research interest in the mental disorders caused by blast-induced traumatic brain injury (bTBI), which has been proved as one of the "signature wounds" in modern battlefield. We reviewed the recent progresses in bTBI-related researches and concluded that the new era of blast injury research has shifted from the traditional physical impairments to cognitive dysfunctional/mental disorders that are proved to be more related to the outcome of combat casualty care.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Blast Injuries
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Brain Injuries, Traumatic
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Cognition Disorders
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mental Disorders
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Research
		                        			
		                        		
		                        	
            
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