Objective:Through the statistics and comparison of SCI papers jointly published by the hospital investigators and university scholars, this paper aims to provide a reference for the next step of interdisciplinary research cooperation in ″medicine, science, engineering and liberal art″.Methods:The collaborative SCI papers were searched from the Science Citation Index expanded (SCIE) database, basic information of the cooperative papers were collected. Taking into consideration of the time spots that 3 years before (2015-2017) and after (2018-2020) when the hospital became affiliated to the university. The number of the paper, paper quality, author's basic information, hospital disciplines and the distribution of department/unit in the university were analyzed.Results:The number of the collaborative papers has increased from 23 to 131. There are statistical significance in both the personnel situations and the qualifications to supervise postgraduate students of the authors. The number of the related hospital departments has increased from 7 to 22, and the number of the universities′ unit increased from 3 to 10.Conclusions:After becoming the university affiliated hospital, the interdisciplinary collaborations in medicine, science, engineering and liberal art have already made some achievements, the breadth and depth of cooperation have been continuously expanded, which is related to the various policies implemented by the hospital and the advantages of interdisciplinary collaboration in resource sharing.