Periodontal disease burden is related to economic level. The burden of periodontal disease in Europe and the Western Pacific, which have higher economic levels, is lower than that in Africa and Southeast Asia. The burden of periodontal disease is mostly concentrated in people over 65 years of age. China currently has the heaviest burden of oral disease in the world; the country’s disability adjusted life years account for 18.69%. There are regional differences in the distribution of periodontal conditions that are related to socioeconomic conditions, dietary habits, and other factors of different regions. Some survey results show that the prevalence of periodontal disease among those in the middle-aged group (45-64 years old) is higher than that among the elderly group (over 65 years old). This is because the oral condition of the elderly group is prone to bias in statistics due to tooth loss and other reasons. The occurrence and development of periodontal disease in the elderly is related to a variety of factors: aging triggers physiological degeneration of periodontal tissue and decline in immune function; weakened mobility and weak oral health awareness lead to insufficient daily oral cleaning; certain systemic diseases can aggravate periodontal tissue inflammation, such as diabetes, osteoporosis, and cognitive impairment; and the cumulative impact of factors such as smoking, high-calorie diet, and nutrient deficiencies on periodontal tissue. At present, China has entered the stage of aging, which means that there is an increase in the burden of oral disease, and this puts higher requirements for the allocation of social medical resources in the future. Therefore, the prevention and treatment of periodontal disease in the elderly population is particularly important. This article, which takes the elderly over 65 years old as the research group, collects and summarizes the prevalence of periodontal disease in this group at home and abroad, and explores the influencing factors of periodontal disease in the elderly. In order to provide a basis for the early prevention of periodontal disease in the elderly, a focus must be placed on disease control and prevention as well as treatment of specific susceptible groups.

Neurofibromatosis type 1 (NF1) presents with a diverse range of symptoms that can affect the skin, bones, eyes, central nervous system, and other organs. This article reports the diagnosis and treatment process of a patient with NF1 complicated by bilateral severe-to-profound sensorineural hearing loss. Genetic testing revealed a heterozygous variant of NF1 NM_ 000267.3: c.4054_ 4058del(p.Ser1352LeufsTer20, supporting the diagnosis of NF1. After thorough evaluation, a right cochlear implantation was performed, yielding satisfactory postoperative results. This case suggests that NF1 patients may exhibit phenotypic heterogeneity and atypicality, providing a reference for clinicians in the diagnosis and treatment of such patients.

Objective:To explore the mediating effect of job resources between self-efficacy and job crafting behavior of Intensive Care Unit (ICU) nurses.Methods:From March to May 2022, 629 ICU nurses from Fuwai Hospital, Chinese Academy of Medical Sciences were selected by cluster sampling as the subjects. The nurses were investigated by using the General Information Questionnaire, Job Crafting Scale (JCS) , the Copenhagen Psychosocial Questionnaire (COPSOQ) , and the General Self-Efficacy Scale (GSES) . Pearson correlation was used to analyze the correlation between ICU nurses' job resources, self-efficacy and job crafting behavior. The mediating effect model was established by AMOS software, and the mediating effect was discussed by Bootstrap test. A total of 629 questionnaires were distributed, and 555 valid questionnaires were collected, and the effective response rate was 88.24% (555/629) .Results:Among 555 ICU nurses, the scores of JCS, job resources and GSES were (77.58±12.53) , (74.35±13.37) and (27.16±5.90) , respectively. Pearson correlation analysis showed that ICU nurses' job crafting behavior was positively correlated with self-efficacy and job resources ( P<0.01) . Bootstrap mediating effect analysis showed that there was a partial mediating effect of job resources between self-efficacy and job crafting behavior of ICU nurses [β= 0.128, 95% CI (0.086, 0.177) ] , accounting for 18.7% of the total effect. Conclusions:ICU nurses' job crafting behavior is at a moderate to upper level. Job resources play a mediating role between self-efficacy and job crafting behavior. Nursing managers should focus on the job crafting behavior of ICU nurses, build a supportive work environment, pay attention to their psychological health, give them correct guidance, and improve the self-efficacy of ICU nurses.

Objective To explore the effect of iliac artery to deep femoral artery angioplasty on the improvement of postoperative lower limb ischemic symptoms and recovery in patients with lower limb arteriosclerosis obliterans(LEASO).Methods One hundred and four LEASO patients in Dongzhimen Hospital of Beijing University of Chinese Medicine from December 2013 to July 2016 were involved in the study and they were divided into control group and observation group according to the treatment program,each group 52 cases.The control group was treated with conservative treatment,and the observation group was treated with iliac artery to deep femoral artery angioplasty.After treatment,the limb ischemic injury degree Rutherford classification and clinical efficacy of the two groups were compared,all patients were followed up for 6 months to compare the survival quality score before and 6-month after treatment.Results (1) Rutherford classification: after treatment,Rutherford classification in the observation group was significantly higher than that of the control group,the result was statistically significant (Z=2.160,P=0.031);(2) Clinical efficacy: the total effective rate in the observation group (94.23% (49/52)) was higher than that of the control group (76.92% (40/52)),the difference was statistically significant (χ2=6.310,P=0.012);(3) Life quality: before treatment,there was no significant difference between the two groups in terms of the quality of life score ((55.01±6.32) points vs.(54.89±6.14) points,t=0.098,P=0.922),but 6 months after treatment,the score of the observation group became higher than that of the control group ((69.63±7.51) points vs.(63.15±6.98) points,t=4.558,P=0.000).Conclusion The treatment of LEASO using iliac artery to deep femoral artery angioplasty can effectively improve patient''s lower limb ischemic symptoms and life quality.