1.Modified double-bundle arthroscopic repair of the anterior cruciate ligament after Sherman type Ⅰ injury
Changbing WANG ; Lilian ZHAO ; Chuying FU ; Yanjin LI
Chinese Journal of Tissue Engineering Research 2025;29(6):1192-1198
		                        		
		                        			
		                        			BACKGROUND:Impaired hamstring muscle strength,anterior patellar pain,high incidence of osteoarthritis,and loss of proprioception after anterior cruciate ligament reconstruction lead to poor functional recovery due to a higher incidence of osteoarthritis and loss of proprioception.Arthroscopic repair of the anterior cruciate ligament combined with dynamic or static internal brace repair preserves the original ligament structure and results in favorable short-term outcomes. OBJECTIVE:To prospectively observe the efficacy and imaging findings of modified double-bundle arthroscopic repair of the anterior cruciate ligament after Sherman type Ⅰ injury METHODS:From January 2020 to September 2022,a total of 60 patients with anterior cruciate ligament injury admitted at the Department of Sports Medicine,Foshan Hospital of Traditional Chinese Medicine were included and divided into two groups(n=30 per group)according to the treatment protocols.The functional repair group was treated with double bundle repair combined with internal brace fixation,and the reconstruction group was treated with single bundle anatomical reconstruction of autologous hamstring muscle.All cases were followed up for 12 months after surgery,and International Knee Documentation Committee score,Lysholm score and KT-1000 difference between the affected and healthy sides of the two groups were evaluated at 3,6 and 12 months after surgery. RESULTS AND CONCLUSION:Three months after surgery,International Knee Documentation Committee scores,Lysholm scores and KT-1000 difference between the affected and healthy sides were significantly different between the two groups(P<0.05),and the functional repair group was better than the reconstruction group.At 6 and 12 months after surgery,there was no significant difference in International Knee Documentation Committee score,Lysholm score and KT-1000 difference between the two groups(P>0.05).To conclude,anterior cruciate ligament repair preserves the original ligament structure,avoids drilling larger marrow tracts and removing autologous tendons for reconstruction,reduces the damage to the original normal structure,and has fewer complications.Early postoperative efficacy is better than that of anterior cruciate ligament reconstruction with stumps,but there is no significant difference in the efficacy of the two groups 6 months after surgery.
		                        		
		                        		
		                        		
		                        	
2.Teaching discussion on improving post competence of medical imaging major students based on non-standardized assessment teaching mode
Guangming HE ; Xiaohong BI ; Hui WU ; Huai CHEN ; Lilian TAN ; Xi LI
Modern Hospital 2023;23(12):1936-1938
		                        		
		                        			
		                        			With the great development of medical education reform,clinical competency has become the requirements and goal of talent training in Medical Imaging in medical universities within and beyond China.The aim of this article is to review the role of non-standardized assessment at raising students'clinical competency in the course of Diagnostic Medical Imaging in our university.To achieve the goal of reinforcing student's thought of medical imaging and their clinical competency,building up high-quality educational evaluation system,strengthening the teaching faculty,facilitating the combination of theory teaching and practice teaching,improving the practice ability and the awareness of services after their formal induction,and therefore cultiva-ting effective and practical medical imaging talents for our nation.
		                        		
		                        		
		                        		
		                        	
3.Non-invasive tests of non-alcoholic fatty liver disease.
Guanlin LI ; Xinrong ZHANG ; Huapeng LIN ; Lilian Yan LIANG ; Grace Lai-Hung WONG ; Vincent Wai-Sun WONG
Chinese Medical Journal 2022;135(5):532-546
		                        		
		                        			
		                        			For the detection of steatosis, quantitative ultrasound imaging techniques have achieved great progress in past years. Magnetic resonance imaging proton density fat fraction is currently the most accurate test to detect hepatic steatosis. Some blood biomarkers correlate with non-alcoholic steatohepatitis, but the accuracy is modest. Regarding liver fibrosis, liver stiffness measurement by transient elastography (TE) has high accuracy and is widely used across the world. Magnetic resonance elastography is marginally better than TE but is limited by its cost and availability. Several blood biomarkers of fibrosis have been used in clinical trials and hold promise for selecting patients for treatment and monitoring treatment response. This article reviews new developments in the non-invasive assessment of non-alcoholic fatty liver disease (NAFLD). Accumulating evidence suggests that various non-invasive tests can be used to diagnose NAFLD, assess its severity, and predict the prognosis. Further studies are needed to determine the role of the tests as monitoring tools. We cannot overemphasize the importance of context in selecting appropriate tests.
		                        		
		                        		
		                        		
		                        			Elasticity Imaging Techniques/methods*
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		                        			Humans
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		                        			Liver/pathology*
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		                        			Liver Cirrhosis/pathology*
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		                        			Magnetic Resonance Imaging/methods*
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		                        			Non-alcoholic Fatty Liver Disease
		                        			
		                        		
		                        	
4. Risk assessment and early warning of imported COVID-19 in 21 cities, Guangdong province
Jianxiong HU ; Tao LIU ; Jianpeng XIAO ; Guanhao HE ; Zuhua RONG ; Lihua YIN ; Donghua WAN ; Weilin ZENG ; Dexin GONG ; Lingchuan GUO ; Zhihua ZHU ; Lilian ZENG ; Min KANG ; Tie SONG ; Haojie ZHONG ; Jianfeng HE ; Limei SUN ; Yan LI ; Wenjun MA
Chinese Journal of Epidemiology 2020;41(5):658-662
		                        		
		                        			
		                        			 Objective  To assess the imported risk of COVID-19 in Guangdong province and its cities, and conduct early warning.     Methods  Data of reported COVID-19 cases and Baidu Migration Index of 21 cities in Guangdong province and other provinces of China as of February 25, 2020 were collected. The imported risk index of each city in Guangdong province were calculated, and then correlation analysis was performed between reported cases and the imported risk index to identify lag time. Finally, we classified the early warming levels of epidemic by imported risk index.    Results  A total of 1 347 confirmed cases were reported in Guangdong province, and 90.0% of the cases were clustered in the Pearl River Delta region. The average daily imported risk index of Guangdong was 44.03. Among the imported risk sources of each city, the highest risk of almost all cities came from Hubei province, except for Zhanjiang from Hainan province. In addition, the neighboring provinces of Guangdong province also had a greater impact. The correlation between the imported risk index with a lag of 4 days and the daily reported cases was the strongest (correlation coefficient: 0.73). The early warning base on cumulative 4-day risk of each city showed that Dongguan, Shenzhen, Zhongshan, Guangzhou, Foshan and Huizhou have high imported risks in the next 4 days, with imported risk indexes of 38.85, 21.59, 11.67, 11.25, 6.19 and 5.92, and the highest risk still comes from Hubei province.    Conclusions  Cities with a large number of migrants in Guangdong province have a higher risk of import. Hubei province and neighboring provinces in Guangdong province are the main source of the imported risk. Each city must strengthen the health management of migrants in high-risk provinces and reduce the imported risk of Guangdong province. 
		                        		
		                        		
		                        		
		                        	
5.Qualitative diagnosis analysis with MRI of huge ovary and adnexal tumors
Wen GAO ; Lilian TAN ; Li ZHANG
Journal of Practical Radiology 2019;35(11):1797-1800,1830
		                        		
		                        			
		                        			Objective To analyze MRI manifestations of huge tumors in ovary and adnexal,to improve qualitative diagnosis and differential diagnosis ability.Methods Thirty-one female patients with huge tumor in pelvic cavity confirmed by surgical pathology underwent preoperative MRI plain scan,DWI and enhancement scan.MRI features were retrospective analysis and compared with pathological results.MRI manifestations included the tumor size,signal intensity,ADC value of the cystic component,ADC value of the solid component and enhanced index.Then,statistical analysis was carried out.Results The mean size of the benign ovary and adnexal tumors was (103.04±32.75)mm,and that of the malignant was (139.29 ±49.20)mm.There was no statistical difference between the two groups (P>0.05).The number of cystic lesions in the benign group was significantly higher than in the malignant group,while the number of the cystic-solid and solid lesions in the benign groups were obviously lower than in the malignant group.The signal intensity of the lesions was statistically different between the two groups (P<0.05).The enhanced index in the malignant group (53.15±13.78)was significantly higher than in the benign group (3 5.3 9 ±8.1 2)(P<0.05).Moreover,the AUC was 0.8 6 1 ,indicating that the diagnostic effect was good.There were no statistical differences in the tumor size,ADC value of the solid component and the cystic component (P>0.05).Conclusion Benign ovary and adnexal tumors are mostly cystic,while malignance are mostly solid-cystic and solid.Enhanced index is helpful for identifying benign and malignant ovary and adnexal tumors.ADC value of cystic and solid component are not useful to identifying benign and malignant tumors.MRI is powerful in diagnosing huge tumor in female genital system and help to qualitative diagnosis.
		                        		
		                        		
		                        		
		                        	
6.Analysis on correlation between serum lipids and thyroid function after discontinuation of thyroid hormone in patients with differentiated thyroid cancer
Lilian LI ; Jianming PENG ; Chunlei YUAN ; Kunyi DENG ; Qingzhu KONG
International Journal of Laboratory Medicine 2017;38(5):646-648
		                        		
		                        			
		                        			Objective To study the correlation between serum lipids and thyroid function after withdrawn of thyroid hormone in the patients with differentiated thyroid cancer .Methods One hundred and thirty cases of differentiated thyroid carcinoma treated by operative therapy in our hospital form August 2014 to August 2015 were selected .Serum FT4 ,TSH ,FT3 ,triglyceride ,total cho-lesterol ,LDL-C ,HDL-C indexes were detected before discontinuation of levothyroxine sodium (L-T4) ,before operation and 3 weeks after drug withdrawn .Thus the correlation between blood lipid levels and thyroid function was analyzed .Results The HDL-C and the TSH level was positively related before operation (P<0 .05) ,other indexes had no obvious correlation with thyroid function (P>0 .05);the blood lipid levels after medication withdrawn had no obvious correlation with thyroid function (P>0 .05);the total cholesterol levels after medication discontinuation had negative correlation with FT 3 and FT4 levels(P<0 .05);HDL-C was nega-tively correlated with FT3 and FT4 levels(P<0 .05) ,and positively correlated with TSH level (P<0 .05);LDL-C was negatively correlated with FT4 (P<0 .05) .Conclusion When the application treatment of thyroid hormone is suspended ,with the TSH level increase ,the HDL-C level has somewhat elevation ;total cholesterol ,HDL-C and LDL-C levels are negatively correlated with FT 3 and FT4 ,after discontinuation of medication withdrawn ,the blood lipids metabolism abnormality is closely related with thyroid function decline .
		                        		
		                        		
		                        		
		                        	
7.Eye Globe Abnormalities on MR and CT in Adults: An Anatomical Approach.
James Thomas Patrick Decourcy HALLINAN ; Premilla PILLAY ; Lilian Hui Li KOH ; Kong Yong GOH ; Wai Yung YU
Korean Journal of Radiology 2016;17(5):664-673
		                        		
		                        			
		                        			Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss.
		                        		
		                        		
		                        		
		                        			Adult*
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		                        			Diagnosis
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		                        			Hemorrhage
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		                        			Humans
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		                        			Magnetic Resonance Imaging
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		                        			Ophthalmology
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		                        			Pathologic Processes
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		                        			Referral and Consultation
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		                        			Retina
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		                        			Rupture
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		                        			Sclera
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		                        			Uvea
		                        			
		                        		
		                        	
8.The clinical characteristics and related factors of cow's milk protein allergy in infants less than 3 months old in Guangxi District
Jing XU ; Shuheng LIANG ; Qiufen WEI ; Yan LI ; Danhua MENG ; Lilian HUANG ; Xinnian PAN
Chinese Pediatric Emergency Medicine 2016;23(2):82-86
		                        		
		                        			
		                        			Objective To study the clinical characteristics and risk factors of cow's milk protein allergy(CMPA)in infants less than 3 months old in Guangxi District.Methods From July 1 ,2012,to December 30,2014,infants less than 3 months old suspected of CMPA visiting the pediatric outpatient depart-ment of Maternal and Children Hospital of Guangxi Zhuang Autonomous Region were recruited,which included initial diagnosis and being transported from peripheral hospitals.Observation scale was formulated, attending physician screened patients and their senior made a definite diagnosis.All the infants underwent diagnostic algorithms and were followed up constantly.Results A total of 137 cases were divided into aller-gy group(n =51 )and control group(n =86).Two groups shared some common symptoms such as diarrhea, constipation,bloody stool,stomachache,gastroesophageal reflux(GER),indigestion,anorexia,feeding diffi-culties.Between the allergy group and control group the parameters such as feeding patterns (including breast feeding,mix feeding,formula feeding),improper deeding of food supplement,long-term use of antibiotics in neonatal period and parental atopy showed no significant differences(P ﹥0.05).The parameters in neonatal period including GER [20 cases (39.2%)vs.7 cases (8.1 %)],intake of cow's milk formula [51 cases (100%)vs.71 cases (82.6%)],feeding intolerance (including GER)[17 cases (33.3%)vs.1 1 cases (12.8%)],gut infection[8 cases(15.7%)vs.4 cases(4.7%)],transfusion of blood or/and bloody prod-ucts[12 cases(23.5%)vs.1 1 cases(12.8%)]showed statistically significant differences between the aller-gy group and control group(χ2 =19.538,P =0.000;χ2 =9.989,P =0.002;χ2 =8.308,P =0.004;χ2 =4.691 ,P =0.030;χ2 =5.198,P =0.023 ).Conclusion Symptoms of CMPA in infants no more than 3 months old involve mainly digestive system such as diarrhea,bloody stool,GER.Intake of cow milk formula in neonatal period play an important role in triggering CMPA.
		                        		
		                        		
		                        		
		                        	
9.Analysis of the effects of the combination of PBL and multimedia network teaching model in the preclinical course of image diagnostics
Xi LI ; Xiaohong BI ; Qinmei LI ; Lin YU ; Yu WEN ; Lilian TAN ; Deji CHEN
Chinese Journal of Medical Education Research 2016;15(7):750-754
		                        		
		                        			
		                        			Objective To investigate the effect of the courses of image diagnostics on clinical pro-bation period via the combination of PBL and multimedia network teaching model. Methods 126 under-graduates from the department of medical image (Grade 2011 and 2012) were selected as teaching subjects, and PBL combined with multimedia network teaching was adopted in the teaching of the course of medical imaging diagnosis. After class we implemented a questionnaire survey, and let the students write learning experience. Statistical analysis was conducted by using SSPS 13.0 to reflect the teaching participation in the students' questionnaire and a. summary analysis of the learning experience of the students was also made. Results 123 valid questionnaires were collected. 94.31%(116 people) of students were active participants in these courses, 90.25%(111 people) of the students thought they could actively communicate in teaching, and 43% (110 people) of the students thought they got fully prepared before class. 123 articles in accor-dance with the requirements of experience were received; most students took positive attitude to the active influence the teaching methods had brought; some student pointed out that the teaching method had the disadvantages such as too much time to prepare, too much information, and so on. Conclusions The com-bination of PBL and multimedia network teaching has preliminary results. It is a novel model that is available for teaching image diagnostics on clinical probation period.
		                        		
		                        		
		                        		
		                        	
10.Meta-analysis for the clinical efficacy of Kangai injection combined with transcatheter arterial chemoembolization for treatment of hepatic cancer
Shichun YANG ; Boyi CHEN ; Song LI ; Rufen OU ; Lilian CHEN
Chinese Journal of Primary Medicine and Pharmacy 2015;22(2):190-193
		                        		
		                        			
		                        			Objective To evaluate the clinical effect of Kangai injection combined with transcatheter arterial chemoembolization (TACE) in the treatment of hepatic cancer.Methods We searched CBM,CNKI,WanFang and VIP,clinical studies of Kangai injection combined with TACE in the treatment of hepatic cancer were included and compared.The methodological quality of included studies was assessed and Meta analysis was performed by Rev Man 5.2 software.Results 9 studies involving 595 patients were included.Meta analysis results indicated that the difference of effective rate was significant [RR =1.32,95 % CI(1.10,1.58),P =0.003] ; The quality of life improvement rate also had significant difference[RR =1.85,95% CI(1.42,2.41),P < 0.000 01].Conclusion Kangai injection combined with TACE in the treatment of hepatic cancer can get extra benefits compared with TACE alone.It can improve the curative effect,significantly improve the quality of life.
		                        		
		                        		
		                        		
		                        	
            
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