OBJECTIVE To explore the changes of brain white matter of the patients with obstructive sleep apnea-hypopnea syndrome(OSAHS)with magnetic resonance diffusional kurtosis imaing(DKI).METHODS There were 38 patients with OSAHS examined by polysomnogram(PSG)from November 2017 to June 2021,and 32 non-OSAHS controls matched in gender and age who were included in this study.All the subjects were scanned by DKI.The different encephalic regions through comparing kurtosis fractional anisotropy(KFA)values of all encephalic regions between the two groups were found,and the relationship between the KFA values of the different encephalic regions in OSAHS patients and the apnea-hypopnea index(AHI),lowest saturation oxygen(LSaO2)and the percent of the total record time spent below 90%oxygen saturation(TS90%)in PSG were analyzed.RESULTS The KFA values of white matter fiber tracts in corpus callosum,bilateral corona radiata,cingulate gyrus,right superior cerebellar peduncle and inferior cerebellar peduncle of OSAHS group were obviously lower than control group(P<0.05).After controlling for age and body mass index(BMI),the partial correlation between AHI and the KFA values of corpus callosum,left posterior corona radiata,right anterior corona radiata,cingulate gyrus in OSAHS group were also negative(r=-0.344,-0.380,-0.406,-0.53,P<0.05).The partial correlation between LSaO2 and the KFA values of corpus callosum,left posterior corona radiata,right anterior corona radiata,cingulate gyrus,right superior cerebellar peduncle in OSAHS group were also positive(r=0.366,0.406,0.446,0.404,0.342,P<0.05).The partial correlation between TS90%and the KFA values of corpus callosum,left posterior corona radiata,right anterior corona radiata,cingulate gyrus,right superior cerebellar peduncle and inferior cerebellar peduncle in OSAHS group were also negative(r=-0.414,-0.352,-0.355,-0.336,-0.456,-0.360,P<0.05).CONCLUSION Recurrent apnea and hypoxemia at night of OSAHS patients can cause damage to white matter fibers in parts of encephalic regions.

Objective To analyze the distribution characteristics of traditional Chinese medicine(TCM)syndrome types in patients with osteoporosis and the distribution differences of clinical and serological indicators in TCM syndrome types.Meth-ods A total of 69 patients with osteoporosis were collected from the Third Affiliated Hospital of Guangzhou University of Chinese Medicine and Qifu Hospital Affiliated to Jinan University.The general information,bone mineral density T value,fasting periph-eral venous blood in the morning were collected.The expression of telomerase protective factor 1(POT1),telomerase reverse transcriptase(TERT),serum 8-hydroxy-2'-deoxyguanosine(8-OHdG)and superoxide dismutase 2(SOD2)were detected by ELISA.Finally,the above data were statistically analyzed.Results There were significant differences in body weight,height,bone mineral density,POT1,TERT,and 8-OHdG among the four syndromes(P＜0.05).In terms of correlation,the relation-ship between bone mineral density and each parameter in different syndrome types was explored.The bone mineral density of qi stagnation and blood stasis syndrome was positively correlated with SOD2 value.There is a positive correlation between bone min-eral density and 8-OHdG in patients with Yin deficiency of liver and kidney.TERT was positively correlated with qi stagnation and blood stasis syndrome.Liver and kidney Yin deficiency syndrome was positively correlated with weight and bone mineral den-sity,and negatively correlated with TERT value.Weight was negatively correlated with qi and blood stasis syndrome.Conclusion In TCM syndrome differentiation of osteoporosis,there were statistical differences in weight,height,bone mineral density,ser-um POT1,TERT and 8-OHdG among Qi-stagnation and blood stasis,spleen-kidney Yang deficiency,liver-kidney Yin deficiency and Qi-blood-peace syndrome.In different syndrome types,serum SOD2 and 8-OHdG were the influencing factors of bone miner-al density.Serum TERT and 8-OHdG are the main factors affecting the dialectical classification of osteoporosis.

Objective Exploring the career mobility intentions of primary care staff in healthcare consortia to provide a basis for decision-making suggestions on the training and retention decisions of medical staff in the medical alli-ance.Methods To investigate the career mobility intention of medical staff in the medical alliance of Guangdong Second People's Hospital as the survey object.Statistical descriptions of the collected key indicators were con-ducted.Pearson chi-square test and t-test for independent samples were used to analyze the differences between groups,and binary logistic regression with single and multiple factors was used to explore the association between potential factors and the idea of staying at the grassroots level.Results A total of 289 medical staff within the health-care consortium were included,with females being the main group at 63.0％,and the highest proportion of staff un-der 40 years of age at 63.6％.Logistic regression analysis result showed a significant positive association between satisfaction with training effect and thoughts of staying on at the primary level only(P<0.05).Conclusion It is possi-ble to explore the construction of a virtuous circulation mechanism of medical talent resources with the medical asso-ciation construction as the carrier,and promote the orderly flow of manpower within the medical association,so as to achieve the"recruiting,well using,promotion and retaining"medical talent people in primary medical institu-tions.

The National Conference on Medical Emergency Work in 2024 clearly puts forward the need to continu-ously strengthen the construction of emergency medical rescue system and capacity,does a good job in medical treatment of emergencies,and achieves high-quality development of medical emergency work.On the basis of ana-lysing the current situation of medical emergency rescue system construction,taking the construction practice of the first emergency hospital in China in Guangdong Second People's Hospital as an example,it explores the construc-tion of a new model of medical emergency rescue in large public hospitals,including three kinds of capabilities:the ability to transform the combination of level and emergency,the ability to integrate regional medical rescue and coor-dination,and three-dimensional multifunctional emergency rescue capabilities;and two norms:norms for talent training and norms for the management system.Finally,it puts forward suggestions for strengthening the construc-tion of emergency hospitals.

Objective Exploring the career mobility intentions of primary care staff in healthcare consortia to provide a basis for decision-making suggestions on the training and retention decisions of medical staff in the medical alli-ance.Methods To investigate the career mobility intention of medical staff in the medical alliance of Guangdong Second People's Hospital as the survey object.Statistical descriptions of the collected key indicators were con-ducted.Pearson chi-square test and t-test for independent samples were used to analyze the differences between groups,and binary logistic regression with single and multiple factors was used to explore the association between potential factors and the idea of staying at the grassroots level.Results A total of 289 medical staff within the health-care consortium were included,with females being the main group at 63.0％,and the highest proportion of staff un-der 40 years of age at 63.6％.Logistic regression analysis result showed a significant positive association between satisfaction with training effect and thoughts of staying on at the primary level only(P<0.05).Conclusion It is possi-ble to explore the construction of a virtuous circulation mechanism of medical talent resources with the medical asso-ciation construction as the carrier,and promote the orderly flow of manpower within the medical association,so as to achieve the"recruiting,well using,promotion and retaining"medical talent people in primary medical institu-tions.

The National Conference on Medical Emergency Work in 2024 clearly puts forward the need to continu-ously strengthen the construction of emergency medical rescue system and capacity,does a good job in medical treatment of emergencies,and achieves high-quality development of medical emergency work.On the basis of ana-lysing the current situation of medical emergency rescue system construction,taking the construction practice of the first emergency hospital in China in Guangdong Second People's Hospital as an example,it explores the construc-tion of a new model of medical emergency rescue in large public hospitals,including three kinds of capabilities:the ability to transform the combination of level and emergency,the ability to integrate regional medical rescue and coor-dination,and three-dimensional multifunctional emergency rescue capabilities;and two norms:norms for talent training and norms for the management system.Finally,it puts forward suggestions for strengthening the construc-tion of emergency hospitals.

Objective Exploring the career mobility intentions of primary care staff in healthcare consortia to provide a basis for decision-making suggestions on the training and retention decisions of medical staff in the medical alli-ance.Methods To investigate the career mobility intention of medical staff in the medical alliance of Guangdong Second People's Hospital as the survey object.Statistical descriptions of the collected key indicators were con-ducted.Pearson chi-square test and t-test for independent samples were used to analyze the differences between groups,and binary logistic regression with single and multiple factors was used to explore the association between potential factors and the idea of staying at the grassroots level.Results A total of 289 medical staff within the health-care consortium were included,with females being the main group at 63.0％,and the highest proportion of staff un-der 40 years of age at 63.6％.Logistic regression analysis result showed a significant positive association between satisfaction with training effect and thoughts of staying on at the primary level only(P<0.05).Conclusion It is possi-ble to explore the construction of a virtuous circulation mechanism of medical talent resources with the medical asso-ciation construction as the carrier,and promote the orderly flow of manpower within the medical association,so as to achieve the"recruiting,well using,promotion and retaining"medical talent people in primary medical institu-tions.

The National Conference on Medical Emergency Work in 2024 clearly puts forward the need to continu-ously strengthen the construction of emergency medical rescue system and capacity,does a good job in medical treatment of emergencies,and achieves high-quality development of medical emergency work.On the basis of ana-lysing the current situation of medical emergency rescue system construction,taking the construction practice of the first emergency hospital in China in Guangdong Second People's Hospital as an example,it explores the construc-tion of a new model of medical emergency rescue in large public hospitals,including three kinds of capabilities:the ability to transform the combination of level and emergency,the ability to integrate regional medical rescue and coor-dination,and three-dimensional multifunctional emergency rescue capabilities;and two norms:norms for talent training and norms for the management system.Finally,it puts forward suggestions for strengthening the construc-tion of emergency hospitals.

Objective Exploring the career mobility intentions of primary care staff in healthcare consortia to provide a basis for decision-making suggestions on the training and retention decisions of medical staff in the medical alli-ance.Methods To investigate the career mobility intention of medical staff in the medical alliance of Guangdong Second People's Hospital as the survey object.Statistical descriptions of the collected key indicators were con-ducted.Pearson chi-square test and t-test for independent samples were used to analyze the differences between groups,and binary logistic regression with single and multiple factors was used to explore the association between potential factors and the idea of staying at the grassroots level.Results A total of 289 medical staff within the health-care consortium were included,with females being the main group at 63.0％,and the highest proportion of staff un-der 40 years of age at 63.6％.Logistic regression analysis result showed a significant positive association between satisfaction with training effect and thoughts of staying on at the primary level only(P<0.05).Conclusion It is possi-ble to explore the construction of a virtuous circulation mechanism of medical talent resources with the medical asso-ciation construction as the carrier,and promote the orderly flow of manpower within the medical association,so as to achieve the"recruiting,well using,promotion and retaining"medical talent people in primary medical institu-tions.

The National Conference on Medical Emergency Work in 2024 clearly puts forward the need to continu-ously strengthen the construction of emergency medical rescue system and capacity,does a good job in medical treatment of emergencies,and achieves high-quality development of medical emergency work.On the basis of ana-lysing the current situation of medical emergency rescue system construction,taking the construction practice of the first emergency hospital in China in Guangdong Second People's Hospital as an example,it explores the construc-tion of a new model of medical emergency rescue in large public hospitals,including three kinds of capabilities:the ability to transform the combination of level and emergency,the ability to integrate regional medical rescue and coor-dination,and three-dimensional multifunctional emergency rescue capabilities;and two norms:norms for talent training and norms for the management system.Finally,it puts forward suggestions for strengthening the construc-tion of emergency hospitals.