1.Application of endoscopic surgical repair through bracing laryngoscope in children with type Ⅲ laryngeal clefts.
Yitian HUANG ; Hongbing YAO ; Xinye TANG ; Yang YANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2023;37(12):948-952
		                        		
		                        			
		                        			Objective:To analyze the efficacy of endoscopic surgical repair in the treatment of type Ⅲ laryngeal clefts and to explore the feasibility of the treatment for type Ⅲ laryngeal clefts. Methods:The clinical data of 6 children with type Ⅲ laryngeal clefts who underwent endoscopic surgical repair in our department from June 2018 to January 2023 were analyzed retrospectively. The operation was performed under combined intravenous and general anesthesia,preserving the spontaneous breathing of the children. With the assistance of 4 mm/0° endoscope, radiofrequency knife or laryngeal scissors were used to make fresh wounds along the edge of laryngeal clefts,and cotton pads infiltrated with adrenaline (1:10 000) were used to compress the wound. 6-0 PDP suture was used to suture 3-6 stitches according to the extent of laryngeal clefts. Modified barium swallowing test (MBS) was performed 3 months after operation. Results:All the children were successfully treated with endoscopic surgical repair. After surgery, 2 cases were transferred to pediatric intensive care unit (ICU) for 7 days of monitoring, and the rest were transferred back to the general ward. There were no postoperative complications. The symptoms of dysphagia, laryngitis and recurrent pneumonia were improved in all children. According to the follow-up results of postoperative MBS,no aspiration was found in all children, and 2 children had intermittent cough when drinking large amounts of water. During the follow-up, there were 2 cases of recurrence, and the cracks were completely repaired after the second endoscopic surgical repair treatment,and no recurrence has been observed so far. Conclusion:Endoscopic surgical repair can be applied to some children with type Ⅲ laryngeal clefts with less intraoperative bleeding and fewer operative complications. It can significantly improve the symptoms such as swallowing dysfunction and recurrent pneumonia. It is a safe and effective surgical treatment.
		                        		
		                        		
		                        		
		                        			Child
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laryngoscopy/methods*
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Larynx/surgery*
		                        			;
		                        		
		                        			Pneumonia
		                        			;
		                        		
		                        			Congenital Abnormalities/surgery*
		                        			
		                        		
		                        	
2.Foreign body aspiration during dental treatment under general anesthesia: A case report
Journal of Dental Anesthesia and Pain Medicine 2019;19(2):119-123
		                        		
		                        			
		                        			Foreign body aspiration in dental clinics is the most common cause of respiratory emergencies. There are no reports on foreign body aspiration during dental treatment under stable general anesthesia because the patient neither has voluntary movements nor reflex actions. This is a case report on the fall of a prosthesis in the larynx, which occurs rarely under general anesthesia. During the try-in procedure, the prosthesis slid from the surgeon's hand and entered the retromylohyoid space, and while searching for it, it passed down the larynx to the endotracheal tube balloon, leading to a dangerous situation. The prosthesis was promptly removed using video-assisted laryngoscope and forceps, and the patient was discharged without any complications.
		                        		
		                        		
		                        		
		                        			Anesthesia, General
		                        			;
		                        		
		                        			Dental Clinics
		                        			;
		                        		
		                        			Emergencies
		                        			;
		                        		
		                        			Foreign Bodies
		                        			;
		                        		
		                        			Hand
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Prostheses and Implants
		                        			;
		                        		
		                        			Reflex
		                        			;
		                        		
		                        			Surgical Instruments
		                        			
		                        		
		                        	
3.A Missed and Delayed Detected Fish Bone Impaction in Subglottis.
Chung Man SUNG ; Hyung Chae YANG ; Sung Min JIN ; Chul Ho JANG
Korean Journal of Otolaryngology - Head and Neck Surgery 2019;62(1):57-59
		                        		
		                        			
		                        			Laryngeal foreign body can be a life-threatening emergency. Respiratory distress, aphonia, and cyanosis may occur in quick succession. However, in case of a non-obstructive laryngeal foreign body, symptoms can be indolent, but the hazardous foreign body can nevertheless put the patient in danger. To prevent life-threatening consequences, early detection based on symptoms is imperative. This case, which presented with usual symptoms of anterior neck pain and throat discomfort without respiratory symptoms and an unusual site of laryngeal foreign body, finally turned out to be an impacted fish bone in the subglottis.
		                        		
		                        		
		                        		
		                        			Aphonia
		                        			;
		                        		
		                        			Cyanosis
		                        			;
		                        		
		                        			Emergencies
		                        			;
		                        		
		                        			Foreign Bodies
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Neck Pain
		                        			;
		                        		
		                        			Pharynx
		                        			;
		                        		
		                        			Trachea
		                        			
		                        		
		                        	
4.Expression of CAIII and Hsp70 Is Increased the Mucous Membrane of the Posterior Commissure in Laryngopharyngeal Reflux Disease.
Hyun Jin MIN ; Seok Chan HONG ; Hoon Shik YANG ; Seog Kyun MUN ; Sei Young LEE
Yonsei Medical Journal 2016;57(2):469-474
		                        		
		                        			
		                        			PURPOSE: We tried to evaluate the difference in the expression of carbonic anhydrase (CA) III and heat shock protein (Hsp) 70 between laryngopharyngeal reflux disease (LPRD) and non-LPRD patients. MATERIALS AND METHODS: The study involved 28 patients who underwent laryngeal microsurgery due to benign laryngeal disease from March to August 2008. Reflux symptom index (RSI) and reflux finding score (RFS) were measured for each person, and they were assigned either to the LPRD group (n=10) or non-LPRD group (n=18). Tissue samples were obtained from the mucosa of posterior commissure, and immunohistochemistry (IHC) staining of CAIII and Hsp70 was performed. The IHC scores were measured and compared with clinical features including RSI and RFS. RESULTS: Total 10 patients were assigned as LPRD group, and 18 patients were as control group. The mean IHC score of CAIII and Hsp70 was 1.70+/-1.06 and 1.90+/-0.88, respectively, in LPRD patients, whereas the mean IHC score of CAIII and Hsp70 was 0.78+/-0.73 and 0.94+/-0.87, respectively, in non-LPRD patients. The difference between two groups was statistically significant (p<0.05). CONCLUSION: CAIII and Hsp70 expressions were higher in LPRD patients that in non-LPRD patients, suggesting the possibility as one of biomomarker in LPRD diagnosis.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Biopsy
		                        			;
		                        		
		                        			Carbonic Anhydrase III/*metabolism
		                        			;
		                        		
		                        			Case-Control Studies
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			HSP70 Heat-Shock Proteins/*metabolism
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Immunohistochemistry
		                        			;
		                        		
		                        			Laryngopharyngeal Reflux/*diagnosis/surgery
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Laryngoscopy
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Mucous Membrane/*metabolism
		                        			
		                        		
		                        	
5.Endoscopic Resection of a Vocal Cord Polyp in a Patient with Difficult Laryngeal Exposure.
Sang Kuk LEE ; Se A LEE ; Seung Jae LEE ; Seung Won LEE
Journal of the Korean Society of Laryngology Phoniatrics and Logopedics 2016;27(2):138-140
		                        		
		                        			
		                        			Vocal cord polyps are generally removed using a direct laryngoscope and surgical microscope. In some case of laryngeal microsurgery, laryngeal exposure with surgical microscope is difficult because of severalfactors. We experienced a case of vocal polyp with difficult laryngeal exposure in a 56 year old male patient. The vocal cord polyp was removed successfully through endoscopic approach.
		                        		
		                        		
		                        		
		                        			Endoscopy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Microsurgery
		                        			;
		                        		
		                        			Polyps*
		                        			;
		                        		
		                        			Vocal Cords*
		                        			
		                        		
		                        	
6.Extraskeletal Myxoid Chondrosarcoma of Larynx.
Ki Ju CHO ; Seong Chul YEO ; Sung Jun WON ; Seung Hoon WOO
Korean Journal of Otolaryngology - Head and Neck Surgery 2016;59(7):527-531
		                        		
		                        			
		                        			Primary cartilaginous tumors of the laryngeal lesion are rare and it accounts for only 1% of laryngeal tumor pathology. They are most commonly located on the endolaryngeal surface of cricoid cartilage, and it is extremely rare to find them in vocal muscle lesion. In most cases, treatment of choice is based on surgical excision, and postoperative radiotherapy is typically recommended. We experienced a case of a 22-year-old young woman without underlying disease, presenting extraskeletal myxoid chondrosarcoma of vocal cord, especially in the vocal muscle. The patient underwent mass excision through suspension laryngoscope and radiation therapy.
		                        		
		                        		
		                        		
		                        			Chondrosarcoma*
		                        			;
		                        		
		                        			Cricoid Cartilage
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laryngeal Muscles
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Larynx*
		                        			;
		                        		
		                        			Pathology
		                        			;
		                        		
		                        			Radiotherapy
		                        			;
		                        		
		                        			Vocal Cords
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
7.Difficult intubation using intubating laryngeal mask airway in conjunction with a fiber optic bronchoscope.
Jin Sun KIM ; Dong Kyun SEO ; Chang Joon LEE ; Hwa Sung JUNG ; Seong Su KIM
Journal of Dental Anesthesia and Pain Medicine 2015;15(3):167-171
		                        		
		                        			
		                        			When anesthesiologists encounter conditions in which intubation is not possible using a conventional direct laryngoscope, they can consider using other available techniques and devices such as fiber optic bronchoscope (FOB)-guided intubation, a laryngeal mask airway (LMA), intubating LMA (ILMA), a light wand, and the Combitube. FOB-guided intubation is frequently utilized in predicted difficult airway cases and is generally performed when the patient is awake to enable easier access to the trachea. An LMA can be introduced to ventilate the patient with relative ease, while an ILMA can be used for definite endotracheal intubation. However, occasionally, an endotracheal tube (ETT) cannot pass through the larynx, despite successful introduction of a FOB into the trachea and placement of an ILMA by the anesthesiologist. Therefore, we initially introduced an ILMA for emergent ventilation, followed by successful insertion of an ETT under FOB guidance. In this report, we describe three cases of difficult intubation using a FOB and ILMA combination approach.
		                        		
		                        		
		                        		
		                        			Bronchoscopes*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intubation*
		                        			;
		                        		
		                        			Intubation, Intratracheal
		                        			;
		                        		
		                        			Laryngeal Masks*
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Nerve Fibers, Myelinated*
		                        			;
		                        		
		                        			Trachea
		                        			;
		                        		
		                        			Ventilation
		                        			
		                        		
		                        	
8.Difficult intubation using intubating laryngeal mask airway in conjunction with a fiber optic bronchoscope.
Jin Sun KIM ; Dong Kyun SEO ; Chang Joon LEE ; Hwa Sung JUNG ; Seong Su KIM
Journal of Dental Anesthesia and Pain Medicine 2015;15(3):167-171
		                        		
		                        			
		                        			When anesthesiologists encounter conditions in which intubation is not possible using a conventional direct laryngoscope, they can consider using other available techniques and devices such as fiber optic bronchoscope (FOB)-guided intubation, a laryngeal mask airway (LMA), intubating LMA (ILMA), a light wand, and the Combitube. FOB-guided intubation is frequently utilized in predicted difficult airway cases and is generally performed when the patient is awake to enable easier access to the trachea. An LMA can be introduced to ventilate the patient with relative ease, while an ILMA can be used for definite endotracheal intubation. However, occasionally, an endotracheal tube (ETT) cannot pass through the larynx, despite successful introduction of a FOB into the trachea and placement of an ILMA by the anesthesiologist. Therefore, we initially introduced an ILMA for emergent ventilation, followed by successful insertion of an ETT under FOB guidance. In this report, we describe three cases of difficult intubation using a FOB and ILMA combination approach.
		                        		
		                        		
		                        		
		                        			Bronchoscopes*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intubation*
		                        			;
		                        		
		                        			Intubation, Intratracheal
		                        			;
		                        		
		                        			Laryngeal Masks*
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Nerve Fibers, Myelinated*
		                        			;
		                        		
		                        			Trachea
		                        			;
		                        		
		                        			Ventilation
		                        			
		                        		
		                        	
9.The related factors analysis of difficult laryngeal exposure under retaining laryngoscope.
Jixuan WANG ; Yanhong HU ; Donghai WANG ; Guofeng ZHAO ; Xiangyu LI ; Yangyang LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(17):1519-1521
		                        		
		                        			OBJECTIVE:
		                        			To analyze the related factors of difficult laryngeal exposure under retaining laryngoscope.
		                        		
		                        			METHOD:
		                        			We did a retrospective analysis of 287 retaining laryngoscope surgery patients' clinical datas to observe the relationship between difficult glottis exposure and patients' gender, degree of mouth opening, BMI, neck circumference, head and neck flexion, TMD, HMD and SMD.
		                        		
		                        			RESULT:
		                        			By ROC curve analysis, we determine the optimal threshold for TMD was 7.35 cm, HMD was 6.33 cm, SMD was 14.75 cm. Univariate analysis showed that gender, and glottis exposure had no significant correlation with difficult laryngeal exposure under retaining laryngoscope. Degree of mouth opening, BMI, neck circumference, head and neck flexion, TMD, HMD and SMD had correlation with difficult laryngeal exposure. Multivariate analysis showed that neck circumference, head and neck flexion, TMD, SMD were independent factors of difficult laryngeal exposure under retaining laryngoscope.
		                        		
		                        			CONCLUSION
		                        			Measurement of neck circumference, head and neck flexion, TMD, SMD before the operation is important for the prediction of difficult laryngeal exposure under retaining laryngoscope.
		                        		
		                        		
		                        		
		                        			Glottis
		                        			;
		                        		
		                        			Head
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Laryngoscopy
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Neck
		                        			;
		                        		
		                        			Posture
		                        			;
		                        		
		                        			ROC Curve
		                        			;
		                        		
		                        			Retrospective Studies
		                        			
		                        		
		                        	
10.Surgical excision and botulinum toxin A injection for vocal process granuloma.
Lijing MA ; Yang XIAO ; Jingying YE ; Qingwen YANG ; Jun WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(2):140-143
		                        		
		                        			OBJECTIVE:
		                        			To study the efficacy of treatment with microsurgery in combination with local injection of type A botulinum toxin for vocal process granuloma.
		                        		
		                        			METHOD:
		                        			28 patients with vocal process granuloma received endotracheal intubation under general anesthesia. The lesion was removed with micro-scissor and CO2 laster under a self-retaining laryngoscope and microscope. The incision and mucous membrane surrounding the wound was closed with 8-0 absorbable suture. 4-point injection of botulinum toxin type A 8-15 u was then performed along the thyroarytenoid muscle and arytenoid muscle of the same side. Postoperative medication was administered based on disease causes.
		                        		
		                        			RESULT:
		                        			All patients experienced vocal cord dyskinesia of the injected side 2-3 days after surgery. At 1 month after the surgery, wound healing was good in all the 28 patients, and the vocal cord movement was limited at the injected side. At 3 months, movement of the bilateral vocal cords was normal, and the vocal cord process mucosa was smooth. Patients were followed up for more than a year, and only one patient had recurrence in 2 months after surgery. The cure rate was 96. 4%.
		                        		
		                        			CONCLUSION
		                        			Combination of laryngeal microsurgery and type A botulinum toxin local injection can shorten the treatment course of vocal process granuloma.
		                        		
		                        		
		                        		
		                        			Anesthesia, General
		                        			;
		                        		
		                        			Botulinum Toxins
		                        			;
		                        		
		                        			administration & dosage
		                        			;
		                        		
		                        			Granuloma
		                        			;
		                        		
		                        			drug therapy
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Injections
		                        			;
		                        		
		                        			Intubation, Intratracheal
		                        			;
		                        		
		                        			Laryngeal Mucosa
		                        			;
		                        		
		                        			Laryngeal Muscles
		                        			;
		                        		
		                        			Laryngeal Neoplasms
		                        			;
		                        		
		                        			drug therapy
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Laryngoscopes
		                        			;
		                        		
		                        			Larynx
		                        			;
		                        		
		                        			Microsurgery
		                        			;
		                        		
		                        			Postoperative Period
		                        			;
		                        		
		                        			Recurrence
		                        			;
		                        		
		                        			Vocal Cords
		                        			;
		                        		
		                        			Wound Healing
		                        			
		                        		
		                        	
            
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