1.Deep learning-based automatic segmentation of the mandibular canal on panoramic radiographs: A multi-device study
Moe Thu Zar AUNG ; Sang-Heon LIM ; Jiyong HAN ; Su YANG ; Ju-Hee KANG ; Jo-Eun KIM ; Kyung-Hoe HUH ; Won-Jin YI ; Min-Suk HEO ; Sam-Sun LEE
Imaging Science in Dentistry 2024;54(1):81-91
Purpose:
The objective of this study was to propose a deep-learning model for the detection of the mandibular canal on dental panoramic radiographs.
Materials and Methods:
A total of 2,100 panoramic radiographs (PANs) were collected from 3 different machines: RAYSCAN Alpha (n=700, PAN A), OP-100 (n=700, PAN B), and CS8100 (n=700, PAN C). Initially, an oral and maxillofacial radiologist coarsely annotated the mandibular canals. For deep learning analysis, convolutional neural networks (CNNs) utilizing U-Net architecture were employed for automated canal segmentation. Seven independent networks were trained using training sets representing all possible combinations of the 3 groups. These networks were then assessed using a hold-out test dataset.
Results:
Among the 7 networks evaluated, the network trained with all 3 available groups achieved an average precision of 90.6%, a recall of 87.4%, and a Dice similarity coefficient (DSC) of 88.9%. The 3 networks trained using each of the 3 possible 2-group combinations also demonstrated reliable performance for mandibular canal segmentation, as follows: 1) PAN A and B exhibited a mean DSC of 87.9%, 2) PAN A and C displayed a mean DSC of 87.8%, and 3) PAN B and C demonstrated a mean DSC of 88.4%.
Conclusion
This multi-device study indicated that the examined CNN-based deep learning approach can achieve excellent canal segmentation performance, with a DSC exceeding 88%. Furthermore, the study highlighted the importance of considering the characteristics of panoramic radiographs when developing a robust deep-learning network, rather than depending solely on the size of the dataset.
2.A case report of an unusual temporomandibular joint mass: Nodular fasciitis
Han-Sol LEE ; Kyu-Young OH ; Ju-Hee KANG ; Jo-Eun KIM ; Kyung-Hoe HUH ; Won-Jin YI ; Min-Suk HEO ; Sam-Sun LEE
Imaging Science in Dentistry 2023;53(1):83-89
Nodular fasciitis (NF) is a benign myofibroblastic proliferation that grows very rapidly, mimicking a sarcoma on imaging. It is treated by local excision, and recurrence has been reported in only a few cases, even when excised incompletely. The most prevalent diagnoses of temporomandibular joint (TMJ) masses include synovial chondromatosis, pigmented villonodular synovitis, and sarcomas. Cases of NF in the TMJ are extremely rare, and only 3 cases have been reported to date. Due to its destructive features and rarity, NF has often been misdiagnosed as a more aggressive lesion, which could expose patients to unnecessary and invasive treatment approaches beyond repair. This report presents a case of NF in the TMJ, focusing on various imaging features, along with a literature review aiming to determine the hallmark features of NF in the TMJ and highlight the diagnostic challenges.
3.Head and neck manifestations of fibrodysplasia ossificans progressiva: Clinical and imaging findings in 2 cases
Gyu-Dong JO ; Ju-Hee KANG ; Jo-Eun KIM ; Won-Jin YI ; Min-Suk HEO ; Sam-Sun LEE ; Kyung-Hoe HUH
Imaging Science in Dentistry 2023;53(3):257-263
Fibrodysplasia ossificans progressiva is a rare hereditary disorder characterized by progressive heterotopic ossifica-tion in muscle and connective tissue, with few reported cases affecting the head and neck region. Although plain radiographic findings and computed tomography features have been well documented, limited reports exist onmagnetic resonance findings. This report presents 2 cases of fibrodysplasia ossificans progressiva, one with limited mouth opening due to heterotopic ossification of the lateral pterygoid muscle and the other with restricted neck movement due to heterotopic ossification of the platysma muscle. Clinical findings of restricted mouth opening or limited neck movement, along with radiological findings of associated heterotopic ossification, should prompt consideration of fibrodysplasia ossificans progressiva in the differential diagnosis. Dentists should be particularly vigilant with patients diagnosed with fibrodysplasia ossificans progressiva to avoid exposure to diagnostic biopsy andinvasive dental procedures.
4.Development and validation of a clinical phantom reproducing various lesions for oral and maxillofacial radiology research
Han-Gyeol YEOM ; Jo-Eun KIM ; Kyung-Hoe HUH ; Won-Jin YI ; Min-Suk HEO ; Sam-Sun LEE
Imaging Science in Dentistry 2023;53(4):345-353
Purpose:
The objective of this study was to propose a method for developing a clinical phantom to reproduce various diseases that are clinically prevalent in the field of dentistry. This could facilitate diverse clinical research without unnecessarily exposing patients to radiation.Material and MethodsThis study utilized a single dry skull, which was visually and radiographically examined to evaluate its condition. Existing lesions on the dry skull were preserved, and other relevant lesions were artificially created as necessary. These lesions were then documented using intraoral radiography and cone-beam computed tomography. Once all pre-existing and reproduced lesions were confirmed by the consensus of 2 oral and maxillofacial radiologists, the skull was embedded in a soft tissue substitute. To validate the process, cone-beam computed tomography scans and panoramic radiographs were obtained of the fabricated phantom. All acquired images were subsequently evaluated.
Results:
Most lesions could be identified on panoramic radiographs, although some sialoliths and cracked teeth were confirmed only through cone-beam computed tomographic images. A small gap was observed between the epoxy resin and the bone structures. However, 2 oral and maxillofacial radiologists agreed that this space did not meaningfully impact the interpretation process.
Conclusion
The newly developed phantom has potential for use as a standardized phantom within the dental field. It may be utilized for a variety of imaging studies, not only for optimization purposes, but also for addressing other experimental issues related to both 2- and 3-dimensional diagnostic radiography.
5.Mucormycosis-related osteomyelitis of the maxilla in a post-COVID-19 patient
Yun-Hui KANG ; Sam-Sun LEE ; Moe Thu Zar AUNG ; Ju-Hee KANG ; Jo-Eun KIM ; Kyung-Hoe HUH ; Min-Suk HEO
Imaging Science in Dentistry 2022;52(4):435-440
Mucormycosis is a rare, invasive fungal infection that progresses aggressively and requires prompt surgery and appropriate treatment. The number of cases of mucormycosis in coronavirus disease 2019 (COVID-19) patients has recently increased, and patients with uncontrolled diabetes mellitus are particularly at an elevated risk of infection. This report presents a case of mucormycosis-related osteomyelitis of the maxilla in a 37-year-old man with diabetes mellitus. The patient complained of severe and persistent pain in the right maxilla, accompanied by increased tooth mobility and headache. On contrast-enhanced computed tomographic images, gas-forming osteomyelitis of the right maxilla was observed. Destruction of the maxilla and palatine bone then proceeded aggressively. Sequestrectomy was performed on the right maxilla, and the histopathological diagnosis was mucormycosis. Further investigation after the first operation revealed the patient's history of COVID-19 infection.
6.Deep learning-based apical lesion segmentation from panoramic radiographs
Il-Seok SONG ; Hak-Kyun SHIN ; Ju-Hee KANG ; Jo-Eun KIM ; Kyung-Hoe HUH ; Won-Jin YI ; Sam-Sun LEE ; Min-Suk HEO
Imaging Science in Dentistry 2022;52(4):351-357
Purpose:
Convolutional neural networks (CNNs) have rapidly emerged as one of the most promising artificial intelligence methods in the field of medical and dental research. CNNs can provide an effective diagnostic methodology allowing for the detection of early-staged diseases. Therefore, this study aimed to evaluate the performance of a deep CNN algorithm for apical lesion segmentation from panoramic radiographs.
Materials and Methods:
A total of 1000 panoramic images showing apical lesions were separated into training (n=800, 80%), validation (n=100, 10%), and test (n=100, 10%) datasets. The performance of identifying apical lesions was evaluated by calculating the precision, recall, and F1-score.
Results:
In the test group of 180 apical lesions, 147 lesions were segmented from panoramic radiographs with an intersection over union (IoU) threshold of 0.3. The F1-score values, as a measure of performance, were 0.828, 0.815, and 0.742, respectively, with IoU thresholds of 0.3, 0.4, and 0.5.
Conclusion
This study showed the potential utility of a deep learning-guided approach for the segmentation of apical lesions. The deep CNN algorithm using U-Net demonstrated considerably high performance in detecting apical lesions.
7.Correlation analysis between radiation exposure and the image quality of cone-beam computed tomography in the dental clinical environment
Chang-Ho SONG ; Han-Gyeol YEOM ; Jo-Eun KIM ; Kyung-Hoe HUH ; Won-Jin YI ; Min-Suk HEO ; Sam-Sun LEE
Imaging Science in Dentistry 2022;52(3):283-288
Purpose:
This study was conducted to measure the radiation exposure and image quality of various cone-beam computed tomography (CBCT) machines under common clinical conditions and to analyze the correlation between them.
Materials and Methods:
Seven CBCT machines used frequently in clinical practice were selected. Because each machine has various sizes of fields of view (FOVs), 1 large FOV and 1 small FOV were selected for each machine. Radiation exposure was measured using a dose-area product (DAP) meter. The quality of the CBCT images was analyzed using 8 image quality parameters obtained using a dental volume tomography phantom. For statistical analysis, regression analysis using a generalized linear model was used.
Results:
Polymethyl-methacrylate (PMMA) noise and modulation transfer function (MTF) 10% showed statistically significant correlations with DAP values, presenting positive and negative correlations, respectively (P<0.05). Image quality parameters other than PMMA noise and MTF 10% did not demonstrate statistically significant correlationswith DAP values.
Conclusion
As radiation exposure and image quality are not proportionally related in clinically used equipment, it is necessary to evaluate and monitor radiation exposure and image quality separately.
8.Radiographic features of cleidocranial dysplasia on panoramic radiographs
Khanthaly SYMKHAMPHA ; Geum Sun AHN ; Kyung-Hoe HUH ; Min-Suk HEO ; Sam-Sun LEE ; Jo-Eun KIM
Imaging Science in Dentistry 2021;51(3):271-278
Purpose:
This study aimed to investigate the panoramic imaging features of cleidocranial dysplasia (CCD) with a relatively large sample.
Materials and Methods:
The panoramic radiographs of 40 CCD patients who visited Seoul National University Dental Hospital between 2004 and 2018 were analyzed. Imaging features were recorded based on the consensus of 2 radiologists according to the following criteria: the number of supernumerary teeth and impacted teeth; the shape of the ascending ramus, condyle, coronoid process, sigmoid notch, antegonial notch, and hard palate; the mandibular midline suture; and the gonial angle.
Results:
The mean number of supernumerary teeth and impacted teeth were 6.1 and 8.3, respectively, and the supernumerary teeth and impacted teeth were concentrated in the anterior and premolar regions. Ramus parallelism was dominant (32 patients, 80.0%) and 5 patients (12.5%) showed a mandibular midline suture. The majority of mandibular condyles showed a rounded shape (61.2%), and most coronoid processes were triangular (43.8%) or round (37.5%). The mean gonial angle measured on panoramic radiographs was 122.6°.
Conclusion
Panoramic radiographs were valuable for identifying the features of CCD and confirming the diagnosis. The presence of numerous supernumerary teeth and impacted teeth, especially in the anterior and premolar regions, and the characteristic shapes of the ramus, condyle, and coronoid process on panoramic radiographs may help to diagnose CCD.
9.Acquired facial lipoatrophy: A report of 3 cases with imaging features
Chena LEE ; Chena LEE ; Jo-Eun KIM ; Jo-Eun KIM ; Won-Jin YI ; Won-Jin YI ; Min-Suk HEO ; Min-Suk HEO ; Sam-Sun LEE ; Sam-Sun LEE ; Sang-Sun HAN ; Sang-Sun HAN ; Soon-Chul CHOI ; Soon-Chul CHOI ; Kyung-Hoe HUH ; Kyung-Hoe HUH
Imaging Science in Dentistry 2020;50(3):255-260
Acquired facial lipoatrophy is a rare disease with an unclear etiology and pathological pathway. The distinct causative factors of this disease have been not elucidated, but it is suspected to be associated with immune systemrelated diseases, most notably AIDS. Although the management of facial lipoatrophy is very important for patients’ social life and mental health, no treatment framework has been developed due to the unknown nature of the disease manifestation. The present case report was designed to provide sequential imaging to visualize the disease progression. The clinical backgrounds of the patients are also introduced, helping characterize this disease entity more clearly for maxillofacial specialists.
10.Erratum to: Development of a new ball-type phantom for evaluation of the image layer of panoramic radiography
Han Gyeol YEOM ; Jo Eun KIM ; Kyung Hoe HUH ; Won Jin YI ; Min Suk HEO ; Sam Sun LEE ; Soon Chul CHOI
Imaging Science in Dentistry 2019;49(2):177-177
The authors would like to correct an error in the publication of the original article. The number in the formula on page 256, right column, line 5 should be ‘346.0121’ instead of ‘3446.0121.’

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