1.Antibacterial effect of lidocaine in various clinical conditions
Hyeon Tae KIM ; Seung Woon LIM ; Kyoung Hoon YIM ; Sang Hi PARK ; Jung Hee CHOI ; Yoo Mee BAE ; Il Dong SHIN ; Young Duck SHIN
Anesthesia and Pain Medicine 2019;14(2):165-171
		                        		
		                        			
		                        			BACKGROUND: Infection, one of the complications associated with procedures, can cause fatal outcomes for patients. Although the local anesthetic agent we use is less susceptible to infection due to its antibacterial action, we performed this study to check the change in the antibacterial effect of lidocaine in various clinical conditions. METHODS: After exposing lidocaine to five contaminated environments, we checked on whether the bacteria could be cultured in blood agar plate (BAP) media. In each contaminated environment, lidocaine was exposed for 4 h (n = 9) and 8 h (n = 9), and the results were compared. Lidocaine was swabbed with chlorhexidine (group A), brought into contact with saliva (group B), skin (group C), an operating room floor and an outpatient room floor (group D), operating room air for 24 h (group A-a), and outpatient room air for 24 h (group A-b). After exposure, the culture was initiated. RESULTS: In 2 of 9 BAP media where lidocaine was exposed to saliva (group B) for 8 h, growth of a colony was observed. In gram staining, it was found to be Streptococcus viridans. No bacteria were found in any other groups. CONCLUSIONS: Though lidocaine has strong antibacterial activity, it has been found that long-term exposure to a contaminated environment reduces its antibacterial activity and that drug contamination can be heavily affected not only by environmental but also human effects. Therefore, the use of aseptic drugs is necessary, and stopping the reuse of the drug is a way to prevent complications, including infection.
		                        		
		                        		
		                        		
		                        			Agar
		                        			;
		                        		
		                        			Bacteria
		                        			;
		                        		
		                        			Chlorhexidine
		                        			;
		                        		
		                        			Drug Contamination
		                        			;
		                        		
		                        			Fatal Outcome
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lidocaine
		                        			;
		                        		
		                        			Operating Rooms
		                        			;
		                        		
		                        			Outpatients
		                        			;
		                        		
		                        			Saliva
		                        			;
		                        		
		                        			Skin
		                        			;
		                        		
		                        			Viridans Streptococci
		                        			
		                        		
		                        	
2.Successful Treatment of a Symptomatic Discal Cyst by Percutaneous C-arm Guided Aspiration.
Hyun Jeong YU ; Chan Jin PARK ; Kyoung Hoon YIM
The Korean Journal of Pain 2016;29(2):129-135
		                        		
		                        			
		                        			Although discal cysts are a rare cause of low back pain and radiculopathy. Currently, surgical excision is usually the first-line treatment for discal cysts. However, alternative treatment methods have been suggested, as in some cases symptoms have improved with interventional therapies. A 27-year-old man presented with an acute onset of severe pain, and was found to have a discal cyst after an open discectomy. The patient underwent cyst aspiration and steroid injection through the facet joint under C-arm guidance. After the procedure, the patient's pain improved to NRS 0-1. On outpatient physical examination 1 week, and 1 and 3 months later, no abnormal neurological symptoms were present, and pain did not persist; thus, follow-up observation was terminated. When a discal cyst is diagnosed, it is more appropriate to consider interventional management instead of surgery as a first-line treatment, while planning for surgical resection if the symptoms do not improve or accompanying neurologic deficits progress.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Diskectomy
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intervertebral Disc
		                        			;
		                        		
		                        			Low Back Pain
		                        			;
		                        		
		                        			Neurologic Manifestations
		                        			;
		                        		
		                        			Outpatients
		                        			;
		                        		
		                        			Physical Examination
		                        			;
		                        		
		                        			Radiculopathy
		                        			;
		                        		
		                        			Zygapophyseal Joint
		                        			
		                        		
		                        	
3.Nineth Rib Syndrome after 10th Rib Resection.
Hyun Jeong YU ; Yu Sub JEONG ; Dong Hoon LEE ; Kyoung Hoon YIM
The Korean Journal of Pain 2016;29(3):185-188
		                        		
		                        			
		                        			The 12th rib syndrome is a disease that causes pain between the upper abdomen and the lower chest. It is assumed that the impinging on the nerves between the ribs causes pain in the lower chest, upper abdomen, and flank. A 74-year-old female patient visited a pain clinic complaining of pain in her back, and left chest wall at a 7 on the 0-10 Numeric Rating scale (NRS). She had a lateral fixation at T12-L2, 6 years earlier. After the operation, she had multiple osteoporotic compression fractures. When the spine was bent, the patient complained about a sharp pain in the left mid-axillary line and radiating pain toward the abdomen. On physical examination, the 10th rib was not felt, and an image of the rib-cage confirmed that the left 10th rib was severed. When applying pressure from the legs to the 9th rib of the patient, pain was reproduced. Therefore, the patient was diagnosed with 9th rib syndrome, and ultrasound-guided 9th and 10th intercostal nerve blocks were performed around the tips of the severed 10th rib. In addition, local anesthetics with triamcinolone were administered into the muscles beneath the 9th rib at the point of the greatest tenderness. The patient's pain was reduced to NRS 2 point. In this case, it is suspected that the patient had a partial resection of the left 10th rib in the past, and subsequent compression fractures at T8 and T9 led to the deformation of the rib cage, causing the tip of the remaining 10th rib to impinge on the 9th intercostal nerves, causing pain.
		                        		
		                        		
		                        		
		                        			Abdomen
		                        			;
		                        		
		                        			Abdominal Pain
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Anesthetics, Local
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fractures, Compression
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intercostal Nerves
		                        			;
		                        		
		                        			Leg
		                        			;
		                        		
		                        			Muscles
		                        			;
		                        		
		                        			Neuralgia
		                        			;
		                        		
		                        			Pain Clinics
		                        			;
		                        		
		                        			Physical Examination
		                        			;
		                        		
		                        			Ribs*
		                        			;
		                        		
		                        			Spine
		                        			;
		                        		
		                        			Thoracic Wall
		                        			;
		                        		
		                        			Thorax
		                        			;
		                        		
		                        			Triamcinolone
		                        			
		                        		
		                        	
4.A Case of Bronchonodal Fistula by Endobronchial Tuberculosis.
Soo Kyoung KANG ; Won Hyuk SHIN ; Seung Hee LEE ; Tae Hoon YIM ; Jee Seon KIM ; Byung Chul KIM ; Hak Ro KIM
Keimyung Medical Journal 2014;33(1):53-58
		                        		
		                        			
		                        			The Bronchial fistula is caused by infection, malignancy, trauma, inflammatory disease and foreign body. The bronchonodal fistula by endobronchial tuberculois is very rare complication. The authors present a 70-year-old man presented with hoarseness and sore throat. This patient diagnosed with endobronchial tuberculosis, which was complicated by bronchonodal fistula by sputum acid fast bacilli stain, bronchoscopy, and chest computed tomography. The patient was treated with antituberculosis therapy for 1 year, and follow up bronchoscopy and radiologic study showed regression of bronchonodal fistula.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Bronchial Fistula
		                        			;
		                        		
		                        			Bronchoscopy
		                        			;
		                        		
		                        			Fistula*
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Foreign Bodies
		                        			;
		                        		
		                        			Hoarseness
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Pharyngitis
		                        			;
		                        		
		                        			Sputum
		                        			;
		                        		
		                        			Thorax
		                        			;
		                        		
		                        			Tuberculosis*
		                        			
		                        		
		                        	
5.Comparison of two dosing schedules of intravenous dexmedetomidine in elderly patients during spinal anesthesia.
Sang Hi PARK ; Young Duck SHIN ; Hyun Jeong YU ; Jin Ho BAE ; Kyoung Hoon YIM
Korean Journal of Anesthesiology 2014;66(5):371-376
		                        		
		                        			
		                        			BACKGROUND: As the number of elder patients grows, spinal anesthesia for such patients are increasing significantly. Any effort is needed to use the least anesthetic drug for maintaining the anesthesia while avoiding hazards of cardio-pulmonary complications. METHODS: American Society of Anesthesiologists physical status classification I and II, Forty five elderly patients (> or = 60 years) who received transurethral resection of the prostate or transurethral resection of the bladder tumor were allocated randomly into three treatment groups. The DMT 0.5 group was designed as with dexmedetomidine 0.5 microg/kg while the DMT 1.0 group has a 1 microg/kg intravenous injection over 10 min before anesthetic induction. The Control group was designed to get a normal saline. Each group was compared regarding the maximum sensory block level, extension of anesthesia, degree of motor block, level of sedation, VAS score and complications. RESULTS: There were no significant differences among the 3 treatment groups regarding the maximum level of sensory block and motor block. However, the duration of sensory block was significantly longer in DMT 1.0 group than in the control group (P = 0.045). Both DMT 1.0 group (median = 3, range = 2-6) and DMT 0.5 group (median = 3, range = 1-6) showed a mean value of 3-4 Ramsay sedation score, which resulted in more excessive sedation and significantly greater incidence of bradycardia compared to the control group. No complications such as hypotension, nausea, tremor, and hypoxia were found during this investigation. CONCLUSIONS: In elder patients, the DMT 1.0 group is effective in duration of sensory block and is superior in the aspect of prolonged duration of sensory block compared to the DMT 0.5 group.
		                        		
		                        		
		                        		
		                        			Aged*
		                        			;
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Anesthesia, Spinal*
		                        			;
		                        		
		                        			Anoxia
		                        			;
		                        		
		                        			Appointments and Schedules*
		                        			;
		                        		
		                        			Bradycardia
		                        			;
		                        		
		                        			Classification
		                        			;
		                        		
		                        			Dexmedetomidine*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypotension
		                        			;
		                        		
		                        			Incidence
		                        			;
		                        		
		                        			Injections, Intravenous
		                        			;
		                        		
		                        			Nausea
		                        			;
		                        		
		                        			Prostate
		                        			;
		                        		
		                        			Tremor
		                        			;
		                        		
		                        			Urinary Bladder Neoplasms
		                        			
		                        		
		                        	
6.Wire-reinforced endotracheal tube fire during tracheostomy: A case report.
Young Duck SHIN ; Seung Woon LIM ; Jin Ho BAE ; Kyoung Hoon YIM ; Jae Hwan SIM ; Eun Jung KWON
Korean Journal of Anesthesiology 2012;63(2):157-160
		                        		
		                        			
		                        			Every operation could have a fire emergency, especially in the case of a tracheostomy. When a flammable gas meets a source of heat, the danger of fire is remarkable. A tracheal tube filled with a high concentration of oxygen is also a great risk factor for fire. Intra-tracheal tube fire is a rare, yet critical emergency with catastrophic consequences. Thus, numerous precautions are taken during a tracheostomy like, use of a special tube to prevent laser damage, ballooning of the tube with normal saline instead of air, and dilution of FiO2 with helium or nitrogen. Since the first recorded cases on tube fires, most of the fires were initiated in the balloon and the tip. In the present case report, however, we came across a fire incidence, which originated from the wire.
		                        		
		                        		
		                        		
		                        			Airway Management
		                        			;
		                        		
		                        			Burns
		                        			;
		                        		
		                        			Emergencies
		                        			;
		                        		
		                        			Fires
		                        			;
		                        		
		                        			Helium
		                        			;
		                        		
		                        			Hot Temperature
		                        			;
		                        		
		                        			Incidence
		                        			;
		                        		
		                        			Nitrogen
		                        			;
		                        		
		                        			Oxygen
		                        			;
		                        		
		                        			Porphyrins
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Tracheostomy
		                        			
		                        		
		                        	
7.Rheumatoid Meningitis: Neurologic Manifestation and Pathologic Findings.
Ki Jeong LEE ; Soo Hwan YIM ; Do Whan KIM ; Seung Woo KIM ; Moon Kyu LEE ; Yang Je CHO ; Byung In LEE ; Kyoung HEO ; Se Hoon KIM
Journal of the Korean Neurological Association 2012;30(4):301-304
		                        		
		                        			
		                        			Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man with the history of rheumatoid arthritis presented with intermittent left leg weakness, seizures and later developed fever and confusion. Brain MRI demonstrated leptomeningeal enhancement in right fronto-parietal area. Brain biopsy revealed multifocal suppurative inflammation. After aggressive immunosuppressive treatment, he had gradually recovered and the lesion was reduced on a follow-up MRI.
		                        		
		                        		
		                        		
		                        			Arthritis, Rheumatoid
		                        			;
		                        		
		                        			Biopsy
		                        			;
		                        		
		                        			Brain
		                        			;
		                        		
		                        			Fever
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Headache
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Inflammation
		                        			;
		                        		
		                        			Leg
		                        			;
		                        		
		                        			Meningitis
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Neurologic Manifestations
		                        			;
		                        		
		                        			Seizures
		                        			;
		                        		
		                        			Seizures, Febrile
		                        			;
		                        		
		                        			Unconsciousness
		                        			
		                        		
		                        	
8.Preemptive analgesic efficacy of ultrasound-guided transversus abdominis plane block in patients undergoing gynecologic surgery via a transverse lower abdominal skin incision.
Hyun Jung SHIN ; Sang Tae KIM ; Kyoung Hoon YIM ; Hyun Su LEE ; Jae Hwan SIM ; Young Duck SHIN
Korean Journal of Anesthesiology 2011;61(5):413-418
		                        		
		                        			
		                        			BACKGROUND: The transversus abdominis plane block is recently described peripheral block to providing analgesia to the anterior abdominal wall. The goal of this study is to evaluate the analgesic efficacy of the ultrasound-guided transversus abdominis plane block (US-TAP block) in patients undergoing gynecologic surgery via a transverse lower abdominal skin incision. METHODS: Thirty-two patients undergoing gynecologic surgery were randomized to undergo standard care such as PCA, or to receive additional US-TAP block with standard care. After general anesthesia induction, a bilateral US-TAP block was performed using 0.375% ropivacaine 20 ml on each side. Postoperative demand of rescue analgesics in PACU and ward were recorded. Each patient was assessed postoperatively by a blinded investigator in the postanesthesia care unit (PACU) and at 2, 6, 10, 24, 48 hr postoperatively to investigate pain, drowsiness, nausea and itch. RESULTS: The US-TAP block reduced pain intensity compared to standard care in the PACU (5.2 +/- 3.1 vs 8.4 +/- 1.3) and at 2, 24 postoperative hours (3.0 +/- 2.4 vs 5.2 +/- 2.4, 0.9 +/- 1.5 vs 2.2 +/- 1.9). Fentanyl requirements in PACU was reduced (20.3 +/- 20.9 vs 62.5 +/- 35.4 microg, P < 0.05). In ward, pethidine requirements was reduced (21.9 +/- 28.7 vs 56.3 +/- 34.8 mg, P < 0.05). CONCLUSIONS: The US-TAP block with standard care provide more effective analgesia after gynecologic surgery via a transverse lower abdominal skin incision.
		                        		
		                        		
		                        		
		                        			Abdominal Wall
		                        			;
		                        		
		                        			Amides
		                        			;
		                        		
		                        			Analgesia
		                        			;
		                        		
		                        			Analgesics
		                        			;
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Anesthesia, General
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fentanyl
		                        			;
		                        		
		                        			Gynecologic Surgical Procedures
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Meperidine
		                        			;
		                        		
		                        			Nausea
		                        			;
		                        		
		                        			Nerve Block
		                        			;
		                        		
		                        			Passive Cutaneous Anaphylaxis
		                        			;
		                        		
		                        			Research Personnel
		                        			;
		                        		
		                        			Skin
		                        			;
		                        		
		                        			Sleep Stages
		                        			
		                        		
		                        	
9.Proposing a Scoring System for the Research Criteria of Complex Regional Pain Syndrome.
Kyoung Hoon YIM ; Soo Young PARK ; Ji Yeon YIM ; Yong Chul KIM ; Sang Chul LEE ; Francis Sangun NAHM
Journal of Korean Medical Science 2011;26(4):568-573
		                        		
		                        			
		                        			This study evaluated the structure of complex regional pain syndrome (CRPS) population and suggested a weighted scoring system to balance on objective signs. One hundred sixty-eight consecutive patients were evaluated using the Budapest Research Criteria (BRC). By using multidimensional scaling and logistic regression analysis, we analyzed the degree of importance and relationships between objective findings. In addition, a receiver operating characteristic curve was constructed using a weighted score derived from the risk ratio as a diagnostic test. There were correlations between skin color change and edema, and between decreased range of motion and motor dysfunction when multidimensional scaling was applied. The trophic change was excluded by a logistic regression (95% CI; 0.80-11.850). The cutoff point based on weighted score derived from the risk ratios for determining CRPS was 7.88. At this point, the sensitivity, specificity, positive predictive value and negative predictive value were 75.0%, 95.3%, 96.3%, and 70.1%, respectively. We propose a weighted scoring system for the BRC using risk ratios of objective signs. Although a thorough systematic review would be required in the future, this study can contribute to reduction of the possible distortion of the feature of CRPS populations by the BRC.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aged, 80 and over
		                        			;
		                        		
		                        			Complex Regional Pain Syndromes/*diagnosis/etiology
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Logistic Models
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Odds Ratio
		                        			;
		                        		
		                        			Predictive Value of Tests
		                        			;
		                        		
		                        			ROC Curve
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			*Severity of Illness Index
		                        			
		                        		
		                        	
10.Pregnancy in Woman with Spinal Cord Stimulator for Complex Regional Pain Syndrome: A Case Report and Review of the Literature.
Hyung Seok YOO ; Francis Sahngun NAHM ; Kyoung Hoon YIM ; Jee Youn MOON ; Yung Suk KIM ; Pyung Bok LEE
The Korean Journal of Pain 2010;23(4):266-269
		                        		
		                        			
		                        			Spinal cord stimulation (SCS) is used to manage chronic pain syndromes and it is accepted a cost-effective therapy. Child-bearing women who had SCS become or choose to become pregnant despite these policies pregnancy is a relative contraindication. A 32-year-old woman had SCS as a treatment for the CRPS I of the left lower extremity. During various check up tests, we happen to find out that her serum beta-hCG was positive and confirmed pregnancy. SCS is not recommended in pregnancy because the effects of SCS on pregnancy and nursing mothers had not been confirmed. However, many female patients suffering from chronic pain may expect future pregnancy and we think that they must be informed about the possibility of pregnancy and the effects of SCS device implantation in the course of pregnancy. First of all, a good outcome requires a multidisciplinary team approach, including obstetrics, neonatology, pain medicine and anesthesia, as was used from an early pregnancy. Unfortunately, she had a misabortrion after 6 weeks.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Chronic Pain
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lower Extremity
		                        			;
		                        		
		                        			Mothers
		                        			;
		                        		
		                        			Neonatology
		                        			;
		                        		
		                        			Obstetrics
		                        			;
		                        		
		                        			Pregnancy
		                        			;
		                        		
		                        			Spinal Cord
		                        			;
		                        		
		                        			Spinal Cord Stimulation
		                        			;
		                        		
		                        			Stress, Psychological
		                        			
		                        		
		                        	
            
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