We report a case of bilateral hand complications following Artecoll injections that were successfully managed with surgical excision and reconstruction using MatriDerm and split-thickness skin grafts. Notably, the patient experienced no postoperative foreign body reactions and achieved excellent functional outcomes, with a complete range of motion at 3.5 years postoperatively. This case underscores the effectiveness of MatriDerm-assisted reconstruction in achieving both functional and aesthetic results.

We report a case of bilateral hand complications following Artecoll injections that were successfully managed with surgical excision and reconstruction using MatriDerm and split-thickness skin grafts. Notably, the patient experienced no postoperative foreign body reactions and achieved excellent functional outcomes, with a complete range of motion at 3.5 years postoperatively. This case underscores the effectiveness of MatriDerm-assisted reconstruction in achieving both functional and aesthetic results.

We report a case of bilateral hand complications following Artecoll injections that were successfully managed with surgical excision and reconstruction using MatriDerm and split-thickness skin grafts. Notably, the patient experienced no postoperative foreign body reactions and achieved excellent functional outcomes, with a complete range of motion at 3.5 years postoperatively. This case underscores the effectiveness of MatriDerm-assisted reconstruction in achieving both functional and aesthetic results.

Although lipoma is a well-known non-malignant tumor, oral cavity lipoma is a rather uncommon disease. Intraoral lipoma originating from the buccal fat pad is an exceptionally rare disorder. Buccal fat pad lipomas typically impair the face's appearance and functionality. The treatment is surgical excision using an intraoral technique, and close identifying of the surrounding anatomical systems, including the parotid duct, vessels, and buccinator branch of the facial nerve. A fifty-year-old patient reported consistently growing swelling of the left cheek. Clinical examination revealed a unilateral mass in the soft tissue. An MRI scan showed a typical picture of a lipoma attached to the buccal fat pad. Surgery was performed to remove the tumor, and the histology report confirmed the clinical diagnosis of lipoma.

Rare endocrine diseases are complex conditions that require lifelong specialized care due to their chronic nature and associated long-term complications. In Korea, a lack of nationwide data on clinical practice and outcomes has limited progress in patient care. Therefore, the Multicenter Networks for Ideal Outcomes of Pediatric Rare Endocrine and Metabolic Disease (OUTSPREAD) study was initiated. This study involves 30 centers across Korea. The study aims to improve the long-term prognosis of Korean patients with rare endocrine diseases by collecting comprehensive clinical data, biospecimens, and patient-reported outcomes to identify complications and unmet needs in patient care. Patients with childhood-onset pituitary, adrenal, or gonadal disorders, such as craniopharyngioma, congenital adrenal hyperplasia (CAH), and Turner syndrome were prioritized. The planned enrollment is 1,300 patients during the first study phase (2022–2024). Clinical, biochemical, and imaging data from diagnosis, treatment, and follow-up during 1980–2023 were retrospectively reviewed. For patients who agreed to participate in the prospective cohort, clinical data and biospecimens will be prospectively collected to discover ideal biomarkers that predict the effectiveness of disease control measures and prognosis. Patient-reported outcomes, including quality of life and depression scales, will be evaluated to assess psychosocial outcomes. Additionally, a substudy on CAH patients will develop a steroid hormone profiling method using liquid chromatography-tandem mass spectrometry to improve diagnosis and monitoring of treatment outcomes. This study will address unmet clinical needs by discovering ideal biomarkers, introducing evidence-based treatment guidelines, and ultimately improving long-term outcomes in the areas of rare endocrine and metabolic diseases.

Although lipoma is a well-known non-malignant tumor, oral cavity lipoma is a rather uncommon disease. Intraoral lipoma originating from the buccal fat pad is an exceptionally rare disorder. Buccal fat pad lipomas typically impair the face's appearance and functionality. The treatment is surgical excision using an intraoral technique, and close identifying of the surrounding anatomical systems, including the parotid duct, vessels, and buccinator branch of the facial nerve. A fifty-year-old patient reported consistently growing swelling of the left cheek. Clinical examination revealed a unilateral mass in the soft tissue. An MRI scan showed a typical picture of a lipoma attached to the buccal fat pad. Surgery was performed to remove the tumor, and the histology report confirmed the clinical diagnosis of lipoma.

Rare endocrine diseases are complex conditions that require lifelong specialized care due to their chronic nature and associated long-term complications. In Korea, a lack of nationwide data on clinical practice and outcomes has limited progress in patient care. Therefore, the Multicenter Networks for Ideal Outcomes of Pediatric Rare Endocrine and Metabolic Disease (OUTSPREAD) study was initiated. This study involves 30 centers across Korea. The study aims to improve the long-term prognosis of Korean patients with rare endocrine diseases by collecting comprehensive clinical data, biospecimens, and patient-reported outcomes to identify complications and unmet needs in patient care. Patients with childhood-onset pituitary, adrenal, or gonadal disorders, such as craniopharyngioma, congenital adrenal hyperplasia (CAH), and Turner syndrome were prioritized. The planned enrollment is 1,300 patients during the first study phase (2022–2024). Clinical, biochemical, and imaging data from diagnosis, treatment, and follow-up during 1980–2023 were retrospectively reviewed. For patients who agreed to participate in the prospective cohort, clinical data and biospecimens will be prospectively collected to discover ideal biomarkers that predict the effectiveness of disease control measures and prognosis. Patient-reported outcomes, including quality of life and depression scales, will be evaluated to assess psychosocial outcomes. Additionally, a substudy on CAH patients will develop a steroid hormone profiling method using liquid chromatography-tandem mass spectrometry to improve diagnosis and monitoring of treatment outcomes. This study will address unmet clinical needs by discovering ideal biomarkers, introducing evidence-based treatment guidelines, and ultimately improving long-term outcomes in the areas of rare endocrine and metabolic diseases.

Although lipoma is a well-known non-malignant tumor, oral cavity lipoma is a rather uncommon disease. Intraoral lipoma originating from the buccal fat pad is an exceptionally rare disorder. Buccal fat pad lipomas typically impair the face's appearance and functionality. The treatment is surgical excision using an intraoral technique, and close identifying of the surrounding anatomical systems, including the parotid duct, vessels, and buccinator branch of the facial nerve. A fifty-year-old patient reported consistently growing swelling of the left cheek. Clinical examination revealed a unilateral mass in the soft tissue. An MRI scan showed a typical picture of a lipoma attached to the buccal fat pad. Surgery was performed to remove the tumor, and the histology report confirmed the clinical diagnosis of lipoma.

Rare endocrine diseases are complex conditions that require lifelong specialized care due to their chronic nature and associated long-term complications. In Korea, a lack of nationwide data on clinical practice and outcomes has limited progress in patient care. Therefore, the Multicenter Networks for Ideal Outcomes of Pediatric Rare Endocrine and Metabolic Disease (OUTSPREAD) study was initiated. This study involves 30 centers across Korea. The study aims to improve the long-term prognosis of Korean patients with rare endocrine diseases by collecting comprehensive clinical data, biospecimens, and patient-reported outcomes to identify complications and unmet needs in patient care. Patients with childhood-onset pituitary, adrenal, or gonadal disorders, such as craniopharyngioma, congenital adrenal hyperplasia (CAH), and Turner syndrome were prioritized. The planned enrollment is 1,300 patients during the first study phase (2022–2024). Clinical, biochemical, and imaging data from diagnosis, treatment, and follow-up during 1980–2023 were retrospectively reviewed. For patients who agreed to participate in the prospective cohort, clinical data and biospecimens will be prospectively collected to discover ideal biomarkers that predict the effectiveness of disease control measures and prognosis. Patient-reported outcomes, including quality of life and depression scales, will be evaluated to assess psychosocial outcomes. Additionally, a substudy on CAH patients will develop a steroid hormone profiling method using liquid chromatography-tandem mass spectrometry to improve diagnosis and monitoring of treatment outcomes. This study will address unmet clinical needs by discovering ideal biomarkers, introducing evidence-based treatment guidelines, and ultimately improving long-term outcomes in the areas of rare endocrine and metabolic diseases.

Although lipoma is a well-known non-malignant tumor, oral cavity lipoma is a rather uncommon disease. Intraoral lipoma originating from the buccal fat pad is an exceptionally rare disorder. Buccal fat pad lipomas typically impair the face's appearance and functionality. The treatment is surgical excision using an intraoral technique, and close identifying of the surrounding anatomical systems, including the parotid duct, vessels, and buccinator branch of the facial nerve. A fifty-year-old patient reported consistently growing swelling of the left cheek. Clinical examination revealed a unilateral mass in the soft tissue. An MRI scan showed a typical picture of a lipoma attached to the buccal fat pad. Surgery was performed to remove the tumor, and the histology report confirmed the clinical diagnosis of lipoma.