1.Association between De Ritis ratio and intraoperative blood transfusion in patients undergoing surgical clipping of unruptured intracranial aneurysms: a single center, retrospective, propensity score-matched study
Ji-Hoon SIM ; Chan-Sik KIM ; Seungil HA ; Hyunkook KIM ; Yong-Seok PARK ; Joung Uk KIM
Korean Journal of Anesthesiology 2024;77(2):246-254
		                        		
		                        			 Background:
		                        			Although  elective surgery for unruptured intracranial aneurysms (UIA) has increased, few studies have evaluated the risk factors for transfusion during UIA surgery. We evaluated the association between the preoperative De Ritis ratio (aspartate transaminase/alanine transaminase) and the incidence of intraoperative transfusion in patients who had undergone surgical UIA clipping.  
		                        		
		                        			Methods:
		                        			Patients who underwent surgical clipping of UIA were stratified into two groups according to the preoperative De Ritis ratio cutoff levels (< 1.54 and ≥ 1.54), and the propensity score (PS)-matching analysis was performed to compare the incidence of intraoperative transfusion. Logistic regression analyses were performed to determine the risk factors for intraoperative transfusion. Net reclassification improvement (NRI) and integrated discrimination improvement (IDI) analyses were performed to verify the improvement in the intraoperative transfusion predictive model upon addition of the De Ritis ratio.  
		                        		
		                        			Results:
		                        			Intraoperative transfusion incidence was 15.4% (77/502). We observed significant differences in the incidence of intraoperative transfusion (16.2% vs. 39.7%, P = 0.004) between the groups after matching. In the logistic regression analyses, the De Ritis ratio ≥ 1.54 was an independent risk factor for transfusion (odds ratio [OR]: 3.04, 95% CI [1.53, 6.03], P = 0.002). Preoperative hemoglobin (Hb) value was a risk factor for transfusion (OR: 0.33, 95% CI [0.24, 0.47], P < 0.001). NRI and IDI analyses showed that the De Ritis ratio improved the intraoperative blood transfusion predictive models (P = 0.031 and P = 0.049, respectively). 
		                        		
		                        			Conclusions
		                        			De Ritis ratio maybe a significant risk factor for intraoperative transfusion in UIA surgery.  
		                        		
		                        		
		                        		
		                        	
2.Effect of a Boarding Restriction Protocol on Emergency Department Crowding
Ji Hwan LEE ; Ji Hoon KIM ; Incheol PARK ; Hyun Sim LEE ; Joon Min PARK ; Sung Phil CHUNG ; Hyeon Chang KIM ; Won Jeong SON ; Yun Ho ROH ; Min Joung KIM
Yonsei Medical Journal 2022;63(5):470-479
		                        		
		                        			 Purpose:
		                        			Access block due to the lack of hospital beds causes crowding of emergency departments (ED). We initiated the “boarding restriction protocol” that limits the time of stay in the ED for patients awaiting hospitalization to 24 hours from arrival. The purpose of this study was to determine the effect of the boarding restriction protocol on ED crowding. 
		                        		
		                        			Materials and Methods:
		                        			The primary outcome was ED occupancy rate, which was calculated as the ratio of the number of occupying patients to the total number of ED beds. Time factors, such as length of stay (LOS), treatment time, and boarding time, were investigated. 
		                        		
		                        			Results:
		                        			The mean of the ED occupancy rate decreased from 1.532±0.432 prior to implementation of the protocol to 1.273±0.353 after (p<0.001). According to time series analysis, the absolute effect caused by the protocol was -0.189 (-0.277 to -0.110) (p=0.001). The proportion of patients with LOS exceeding 24 hours decreased from 7.6% to 4.0% (p<0.001). Among admitted patients, ED LOS decreased from 770.7 (421.4–1587.1) minutes to 630.2 (398.0–1156.8) minutes (p<0.001); treatment time increased from 319.6 (198.5–482.8) minutes to 344.7 (213.4–519.5) minutes (p<0.001); and boarding time decreased from 298.9 (109.5–1149.0) minutes to 204.1 (98.7–545.7) minutes (p<0.001). In pre-protocol period, boarding patients accumulated in the ED during the weekdays and resolved on Friday, but this pattern was alleviated in post-period. 
		                        		
		                        			Conclusion
		                        			The boarding restriction protocol was effective in alleviating ED crowding by reducing the accumulation of boarding patients in the ED during the weekdays 
		                        		
		                        		
		                        		
		                        	
3.A Comparative Study on the Nursing Dependency of Suspected COVID-19 Patients and General Patients in the Emergency Department
Seung Yeon BAIK ; Sol Mi PARK ; Ju Hee JEONG ; Moon Joung KIM ; Su Bin PARK ; Hyo Jin LEE ; Ji Young CHOI ; Hyo Eun KWAK ; Jung Hyen LIM ; Hyun Sim LEE
Journal of Korean Clinical Nursing Research 2021;27(2):199-209
		                        		
		                        			Purpose:
		                        			This study was conducted to investigate the nursing needs and workload of nurses according to nursing dependency for effective placement of nursing staff in the emergency department (ED). 
		                        		
		                        			Methods:
		                        			In June 2020, 256 adult patients who visited the ED were classified as two groups, suspected COVID-19 patients and general patients. The participants’electronic medical records were analyzed using descriptive statistics, t-test, x 2 -test, and Fisher's exact test using the SPSS. 
		                        		
		                        			Results:
		                        			The patient dependence score showed a significant difference between the two groups, with an average of 13.99±1.85 for the suspected COVID-19 patient group and 10.58±2.10 for the general patient group (t=12.42, p<.001). There were statistically significant differences in communication (t=3.28, p=.001), mobility (t=3.29, p=.001), nutrition, elimination, and personal care (t=7.34, p<.001) among the six domains of nursing dependency. In the domains of environment, safety, health, and social needs, the dependency score was 3 for all suspected COVID-19 patients and 1 for all general patients. 
		                        		
		                        			Conclusion
		                        			The results of this study confirmed that infection control activities of emergency patients who need isolation affect the patients’ nursing dependency on nursing care.
		                        		
		                        		
		                        		
		                        	
4.A Comparative Study on the Nursing Dependency of Suspected COVID-19 Patients and General Patients in the Emergency Department
Seung Yeon BAIK ; Sol Mi PARK ; Ju Hee JEONG ; Moon Joung KIM ; Su Bin PARK ; Hyo Jin LEE ; Ji Young CHOI ; Hyo Eun KWAK ; Jung Hyen LIM ; Hyun Sim LEE
Journal of Korean Clinical Nursing Research 2021;27(2):199-209
		                        		
		                        			Purpose:
		                        			This study was conducted to investigate the nursing needs and workload of nurses according to nursing dependency for effective placement of nursing staff in the emergency department (ED). 
		                        		
		                        			Methods:
		                        			In June 2020, 256 adult patients who visited the ED were classified as two groups, suspected COVID-19 patients and general patients. The participants’electronic medical records were analyzed using descriptive statistics, t-test, x 2 -test, and Fisher's exact test using the SPSS. 
		                        		
		                        			Results:
		                        			The patient dependence score showed a significant difference between the two groups, with an average of 13.99±1.85 for the suspected COVID-19 patient group and 10.58±2.10 for the general patient group (t=12.42, p<.001). There were statistically significant differences in communication (t=3.28, p=.001), mobility (t=3.29, p=.001), nutrition, elimination, and personal care (t=7.34, p<.001) among the six domains of nursing dependency. In the domains of environment, safety, health, and social needs, the dependency score was 3 for all suspected COVID-19 patients and 1 for all general patients. 
		                        		
		                        			Conclusion
		                        			The results of this study confirmed that infection control activities of emergency patients who need isolation affect the patients’ nursing dependency on nursing care.
		                        		
		                        		
		                        		
		                        	
5.The impact of emergency department expansion on crowding and patient flow
Hyunji YOON ; Hyun Sim LEE ; Joon Min PARK ; Ji Hoon KIM ; Ji Hwan LEE ; In Cheol PARK ; Sung Phil CHUNG ; Min Joung KIM
Journal of the Korean Society of Emergency Medicine 2020;31(4):420-429
		                        		
		                        			 Objective:
		                        			Overcrowding in the emergency department (ED) has been a long-standing global problem, but has yet to be resolved. This study was undertaken to investigate whether expansion of the ED can affect overcrowding. 
		                        		
		                        			Methods:
		                        			This was a retrospective study comparing two 10-month periods: before (September 2015 to June 2016) and after (September 2017 to June 2018) the ED expansion in an urban tertiary hospital. The ED expansion included expansion of the ambulatory area and establishment of a 25-bedded emergency ward dedicated to patients admitted through the ED. 
		                        		
		                        			Results:
		                        			Comparing the two study periods, we noted an increase in the number of patients visiting the ED, from 77,078 to 87,027. Moreover, the proportion of patients who returned home untreated significantly decreased from 11.5% to 0.9% (P<0.001). The number of adult patients increased from 40,814 to 60,720; in particular, the number of ambulatory patients increased from 18,648 to 42,944. Conversely, waiting time for X-ray and computed tomography increased (10.0 to 17.0 minutes, and 35.0 to 48.0 minutes, respectively). Other areas with increased time duration include median ED length of stay of total patients (193.0 minutes to 205.8 minutes), and time from consultation to admission decision (122.3 to 161.4 minutes). However, the boarding time decreased from 239.2 to 190.9 minutes. 
		                        		
		                        			Conclusion
		                        			The ED expansion allowed more patients to be treated, and the boarding time of admitted patients was reduced through operation of the emergency ward. However, due to increase in the number of visiting patients, the time required for medical treatment increased concurrently. 
		                        		
		                        		
		                        		
		                        	
6.A Case of Podostroma Cornu-Damae Intoxication Induced Pancytopenia and Skin Desquamation: Successful Treatment with Granulocyte Colony Stimulation Factor (G-CFS).
Jung Seok KIM ; Gyu Won KIM ; Jae Il CHUNG ; Myoung Ki SIM ; Ki Chul YOON ; Yong Hoon CHOI ; Ha Ram YI ; In Zoo CHOI ; Chan Sup SHIM ; Joung Ho HAN
Journal of The Korean Society of Clinical Toxicology 2015;13(1):50-54
		                        		
		                        			
		                        			Podostroma cornu-damae is a rare species of fungus belonging to the Hyocreaceae family. Its fruit body is highly toxic, as it contains trichothecene mycotoxins. The morphology is similar to that of immature Ganoderma lucidum, making identification difficult for non-experts. We experienced such a case of a 56- year-old male who picked and consumed podostroma cornu-damae, and consumed. Later that day, he developed digestive system symptoms, including nausea, vomiting, and abdominal pain. He presented to the emergency room (ER), there were no abnormal physical findings, symptoms improved after gastric lavage, and the patient voluntarily discharged himself on the same day. The following day, as the symptoms gradually deteriorated, he was admitted via the ER. He was presented with severe pancytopenia, alopecia, desquamation of skin, and acute renal failure. He recovered without any complications after conservative care, antibiotics therapy, and granulocyte colony stimulating factor administration. The most commonly reported complications of podostroma cornu-damae intoxication were reported pancytopenia, infection, disseminated intravascular coagulation, acute renal failure, etc. since Prevention is especially important because its toxicity can be lethal and there is no particular treatment to date, prevention is especially important. Promotion and education for the public are needed.
		                        		
		                        		
		                        		
		                        			Abdominal Pain
		                        			;
		                        		
		                        			Acute Kidney Injury
		                        			;
		                        		
		                        			Agaricales
		                        			;
		                        		
		                        			Alopecia
		                        			;
		                        		
		                        			Anti-Bacterial Agents
		                        			;
		                        		
		                        			Colony-Stimulating Factors
		                        			;
		                        		
		                        			Digestive System
		                        			;
		                        		
		                        			Disseminated Intravascular Coagulation
		                        			;
		                        		
		                        			Education
		                        			;
		                        		
		                        			Emergency Service, Hospital
		                        			;
		                        		
		                        			Fruit
		                        			;
		                        		
		                        			Fungi
		                        			;
		                        		
		                        			Gastric Lavage
		                        			;
		                        		
		                        			Granulocytes*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Mycotoxins
		                        			;
		                        		
		                        			Nausea
		                        			;
		                        		
		                        			Pancytopenia*
		                        			;
		                        		
		                        			Reishi
		                        			;
		                        		
		                        			Skin*
		                        			;
		                        		
		                        			Vomiting
		                        			
		                        		
		                        	
7.Monitored anesthesia care with dexmedetomidine in transfemoral percutaneous trans-catheter aortic valve implantation: two cases report.
Hee Sun PARK ; Kyung Mi KIM ; Kyoung Woon JOUNG ; In Cheol CHOI ; Ji Yeon SIM
Korean Journal of Anesthesiology 2014;66(4):317-321
		                        		
		                        			
		                        			Percutaneous trans-catheter aortic valve implantation (TAVI) is recommended for inoperable patients with severe aortic stenosis at high risk for conventional aortic valve replacement. Originally, TAVI was mostly performed under general anesthesia. Here we describe two cases of transfemoral TAVI performed under monitored anesthesia care (MAC) with dexmedetomidine. Dexmedetomidine provides sedation, analgesia with minimal respiratory depression. Although MAC during transfemoral TAVI has limitations, such as unexpected patient movement and difficulty in intra-procedural use of transesophageal echocardiography, MAC with dexmedetomidine is feasible with close monitoring, fluoroscopic guidance and the participation of experienced anesthesiologists.
		                        		
		                        		
		                        		
		                        			Analgesia
		                        			;
		                        		
		                        			Anesthesia*
		                        			;
		                        		
		                        			Anesthesia, General
		                        			;
		                        		
		                        			Aortic Valve Stenosis
		                        			;
		                        		
		                        			Aortic Valve*
		                        			;
		                        		
		                        			Dexmedetomidine*
		                        			;
		                        		
		                        			Echocardiography, Transesophageal
		                        			;
		                        		
		                        			Heart Valve Prosthesis Implantation
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypnotics and Sedatives
		                        			;
		                        		
		                        			Respiratory Insufficiency
		                        			
		                        		
		                        	
8.Effect of remote ischemic preconditioning on cognitive function after off-pump coronary artery bypass graft: a pilot study.
Kyoung Woon JOUNG ; Jin Ho RHIM ; Ji Hyun CHIN ; Wook Jong KIM ; Dae Kee CHOI ; Eun Ho LEE ; Kyung Don HAHM ; Ji Yeon SIM ; In Cheol CHOI
Korean Journal of Anesthesiology 2013;65(5):418-424
		                        		
		                        			
		                        			BACKGROUND: Several studies have shown in animal models that remote ischemic preconditioning (rIPC) has a neuroprotective effect. However, a randomized controlled trial in human subjects to investigate the neuroprotective effect of rIPC after cardiac surgery has not yet been reported. Therefore, we performed this pilot study to determine whether rIPC reduced the occurrence of postoperative cognitive dysfunction in patients who underwent off-pump coronary artery bypass graft (OPCAB) surgery. METHODS: Seventy patients who underwent OPCAB surgery were assigned to either the control or the rIPC group using a computer-generated randomization table. The application of rIPC consisted of four cycles of 5 min ischemia and 5 min reperfusion on an upper limb using a blood pressure cuff inflating 200 mmHg before coronary artery anastomosis. The cognitive function tests were performed one day before surgery and again on postoperative day 7. We defined postoperative cognitive dysfunction as decreased postoperative test values more than 20% of the baseline values in more than two of the six cognitive function tests that were performed. RESULTS: In the cognitive function tests, there were no significant differences in the results obtained during the preoperative and postoperative periods for all tests and there were no mean differences observed in the preoperative and postoperative scores. The incidences of postoperative cognitive dysfunction in the control and rIPC groups were 28.6% (10 patients) and 31.4% (11 patients), respectively. CONCLUSIONS: rIPC did not reduce the incidence of postoperative cognitive dysfunction after OPCAB surgery during the immediate postoperative period.
		                        		
		                        		
		                        		
		                        			Blood Pressure
		                        			;
		                        		
		                        			Coronary Artery Bypass, Off-Pump*
		                        			;
		                        		
		                        			Coronary Vessels
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Incidence
		                        			;
		                        		
		                        			Ischemia
		                        			;
		                        		
		                        			Ischemic Preconditioning*
		                        			;
		                        		
		                        			Models, Animal
		                        			;
		                        		
		                        			Neuroprotective Agents
		                        			;
		                        		
		                        			Pilot Projects*
		                        			;
		                        		
		                        			Postoperative Period
		                        			;
		                        		
		                        			Random Allocation
		                        			;
		                        		
		                        			Reperfusion
		                        			;
		                        		
		                        			Thoracic Surgery
		                        			;
		                        		
		                        			Transplants*
		                        			;
		                        		
		                        			Upper Extremity
		                        			
		                        		
		                        	
9.Effects of Emotional Labor, Emotional Intelligence and Social Support on Job Stress in Clinical Nurses.
Joo Hyun KIM ; Yong Mi LEE ; Hye Young JOUNG ; Hyun Sim CHOO ; Su Jin WON ; Sue Young KWON ; Hye Jin BAE ; Hye Kyung AHN ; Eun Mi KIM ; Hyun Jung JANG
Journal of Korean Academy of Fundamental Nursing 2013;20(2):157-167
		                        		
		                        			
		                        			PURPOSE: The purpose of this study was to investigate the effects of emotional labor, emotional intelligence and social support on job stress in clinical nurses. METHODS: Participants were 123 clinical nurses and data were collected from October to December, 2011 and analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients and multiple regression with SPSS 18.0. RESULTS: A positive correlation was found between job stress and emotional labor. Emotional labor showed a significant negative correlation with emotional intelligence and social support, whereas a positive correlation was found between emotional intelligence and social support. The strongest predictor of job stress was emotional labor. In addition, institution satisfaction (dissatisfaction) and the reason for selecting the job (opportunities for service) accounted for 21% of variance in job stress. CONCLUSION: The results of this study suggest that it is important to manage emotional labor as well as to improve job satisfaction in order to reduce job stress in clinical nurses.
		                        		
		                        		
		                        		
		                        			Emotional Intelligence
		                        			;
		                        		
		                        			Job Satisfaction
		                        			
		                        		
		                        	
10.Validation of Termination Guidelines for Out of Hospital Cardiac Arrest in Korea.
Jong Geun EUN ; Min Seob SIM ; Keun Jeong SONG ; Mi Kyong KWON ; Sang hyun PARK ; Jun Seob SHIN ; Min Joung KIM ; Sung Pil CHUNG ; Hahn Shick LEE
Journal of the Korean Society of Emergency Medicine 2011;22(6):599-604
		                        		
		                        			
		                        			PURPOSE: There have been no studies on the termination of resuscitation (TOR) in Korea. We retrospectively applied TOR rules to OHCA patient data in order to validate the BLS and ALS TOR rules for Korea. METHODS: We collected OHCA (out-of-hospital cardiac arrest) data from 3 hospitals for the period January 1 to December 31, 2009. We then retrospectively applied BLS and ALS TOR rules to this data. We measured both the specificity and positive predictive value for each BLS and ALS TOR rule. RESULTS: The overall rate of survival until hospital discharge was 14.5%. Out of 102 patients who met BLS criteria TOR rules, 8 patients survived until hospital discharge. Out of 52 patients who met ALS criteria TOR rules, 4 patients survived until hospital discharge. The BLS rule had a specificity of 0.57 and a positive predictive value of 0.92. The ALS rule had a specificity of 0.78 and a positive predictive value of 0.92. CONCLUSION: In this study, the BLS and ALS TOR rules had relatively low positive predictive value and were not applicable to patients with low survival probability in Korea.
		                        		
		                        		
		                        		
		                        			Cardiopulmonary Resuscitation
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Korea
		                        			;
		                        		
		                        			Out-of-Hospital Cardiac Arrest
		                        			;
		                        		
		                        			Resuscitation
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Sensitivity and Specificity
		                        			
		                        		
		                        	
            
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