1.Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications
Jooyeop LEE ; Na Keum LEE ; Joon Ho MOON
Endocrinology and Metabolism 2025;40(1):10-25
Gestational diabetes mellitus (GDM) affects over 10% of all pregnancies, both in Korea and worldwide. GDM not only increases the risk of adverse pregnancy outcomes such as preeclampsia, preterm birth, macrosomia, neonatal hypoglycemia, and shoulder dystocia, but it also significantly increases the risk of developing postpartum type 2 diabetes mellitus and cardiovascular disease in the mother. Additionally, GDM is linked to a higher risk of childhood obesity and diabetes in offspring, as well as neurodevelopmental disorders, including autistic spectrum disorder. This review offers a comprehensive summary of clinical epidemiological studies concerning maternal and fetal complications and explores mechanistic investigations that reveal the underlying pathophysiology.
2.Rare Prevotella bivia infection after liposuction and fat graft: two case reports
Jooyeop LEE ; In Sik YUN ; Tai Suk ROH ; Young Seok KIM ; Kyunghyun MIN
Archives of Aesthetic Plastic Surgery 2025;31(1):21-25
Liposuction and fat grafting are commonly employed to improve body contouring. While postoperative infections are infrequent, severe complications like necrotizing fasciitis can arise, potentially destroying the aesthetic results. Prevotella bivia is an anaerobic, Gram-negative rod bacterium commonly found in the vaginal mucosa, with increased prevalence in cases of bacterial vaginosis. Infections caused by this species can lead to necrotizing fasciitis or extensive tissue necrosis, necessitating prompt diagnosis during the acute phase. This report presents two severe cases of infection caused by P. bivia following fat harvesting and grafting procedures. These cases required multiple debridements, skin grafts, and fasciotomies for management.
3.Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications
Jooyeop LEE ; Na Keum LEE ; Joon Ho MOON
Endocrinology and Metabolism 2025;40(1):10-25
Gestational diabetes mellitus (GDM) affects over 10% of all pregnancies, both in Korea and worldwide. GDM not only increases the risk of adverse pregnancy outcomes such as preeclampsia, preterm birth, macrosomia, neonatal hypoglycemia, and shoulder dystocia, but it also significantly increases the risk of developing postpartum type 2 diabetes mellitus and cardiovascular disease in the mother. Additionally, GDM is linked to a higher risk of childhood obesity and diabetes in offspring, as well as neurodevelopmental disorders, including autistic spectrum disorder. This review offers a comprehensive summary of clinical epidemiological studies concerning maternal and fetal complications and explores mechanistic investigations that reveal the underlying pathophysiology.
4.Rare Prevotella bivia infection after liposuction and fat graft: two case reports
Jooyeop LEE ; In Sik YUN ; Tai Suk ROH ; Young Seok KIM ; Kyunghyun MIN
Archives of Aesthetic Plastic Surgery 2025;31(1):21-25
Liposuction and fat grafting are commonly employed to improve body contouring. While postoperative infections are infrequent, severe complications like necrotizing fasciitis can arise, potentially destroying the aesthetic results. Prevotella bivia is an anaerobic, Gram-negative rod bacterium commonly found in the vaginal mucosa, with increased prevalence in cases of bacterial vaginosis. Infections caused by this species can lead to necrotizing fasciitis or extensive tissue necrosis, necessitating prompt diagnosis during the acute phase. This report presents two severe cases of infection caused by P. bivia following fat harvesting and grafting procedures. These cases required multiple debridements, skin grafts, and fasciotomies for management.
5.Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications
Jooyeop LEE ; Na Keum LEE ; Joon Ho MOON
Endocrinology and Metabolism 2025;40(1):10-25
Gestational diabetes mellitus (GDM) affects over 10% of all pregnancies, both in Korea and worldwide. GDM not only increases the risk of adverse pregnancy outcomes such as preeclampsia, preterm birth, macrosomia, neonatal hypoglycemia, and shoulder dystocia, but it also significantly increases the risk of developing postpartum type 2 diabetes mellitus and cardiovascular disease in the mother. Additionally, GDM is linked to a higher risk of childhood obesity and diabetes in offspring, as well as neurodevelopmental disorders, including autistic spectrum disorder. This review offers a comprehensive summary of clinical epidemiological studies concerning maternal and fetal complications and explores mechanistic investigations that reveal the underlying pathophysiology.
6.Rare Prevotella bivia infection after liposuction and fat graft: two case reports
Jooyeop LEE ; In Sik YUN ; Tai Suk ROH ; Young Seok KIM ; Kyunghyun MIN
Archives of Aesthetic Plastic Surgery 2025;31(1):21-25
Liposuction and fat grafting are commonly employed to improve body contouring. While postoperative infections are infrequent, severe complications like necrotizing fasciitis can arise, potentially destroying the aesthetic results. Prevotella bivia is an anaerobic, Gram-negative rod bacterium commonly found in the vaginal mucosa, with increased prevalence in cases of bacterial vaginosis. Infections caused by this species can lead to necrotizing fasciitis or extensive tissue necrosis, necessitating prompt diagnosis during the acute phase. This report presents two severe cases of infection caused by P. bivia following fat harvesting and grafting procedures. These cases required multiple debridements, skin grafts, and fasciotomies for management.
7.Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications
Jooyeop LEE ; Na Keum LEE ; Joon Ho MOON
Endocrinology and Metabolism 2025;40(1):10-25
Gestational diabetes mellitus (GDM) affects over 10% of all pregnancies, both in Korea and worldwide. GDM not only increases the risk of adverse pregnancy outcomes such as preeclampsia, preterm birth, macrosomia, neonatal hypoglycemia, and shoulder dystocia, but it also significantly increases the risk of developing postpartum type 2 diabetes mellitus and cardiovascular disease in the mother. Additionally, GDM is linked to a higher risk of childhood obesity and diabetes in offspring, as well as neurodevelopmental disorders, including autistic spectrum disorder. This review offers a comprehensive summary of clinical epidemiological studies concerning maternal and fetal complications and explores mechanistic investigations that reveal the underlying pathophysiology.

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