1.Expert consensus on oral corticosteroid use and tapering in severe asthma management
Joo-Hee KIM ; Noeul KANG ; Sung-Yoon KANG ; Da Woon SIM ; So-Young PARK ; Jong-Sook PARK ; Hyun LEE ; Hyun Jung JIN ; Woo-Jung SONG ; So Ri KIM ; Sang-Heon KIM
Allergy, Asthma & Respiratory Disease 2025;13(1):12-21
		                        		
		                        			
		                        			 Systemic corticosteroids play an essential role in the management of asthma. During acute exacerbation, the short-term use of systemic corticosteroids is recommended. For patients with uncontrolled asthma and severe asthma, long-term and low-dose oral corticosteroids (OCS) have frequently been advocated. However, both short-term and long-term use of systemic corticosteroids carry the risk of adverse events (AEs), including various morbidities and even mortality. Despite recent progress in adult severe asthma management and the availability of new treatment options, the current domestic guidelines for asthma do not provide specific recommendations for oral corticosteroid tapering in patients with severe asthma. Therefore, the task force team of the severe asthma working group in the Korean Academy of Allergy, Asthma, and Clinical Immunology has proposed a tapering protocol for systemic corticosteroid use in severe asthma. This includes practical recommendations for monitoring OCS-related AE, particularly for adrenal insufficiency and osteoporosis, which suggests corticosteroid-sparing strategies that include alternative therapies, modifying treatable traits, timely specialist assessment, and shared decision-making with patients. However, further real-world research and collaboration with doctors from primary and academic institutes, patients, and policymakers are necessary to establish an OCS stewardship approach. This should include realistic OCS-tapering strategies for patients with severe asthma using regular OCS, education, and campaigns for patients, the public, and healthcare providers about the burden of severe asthma, as well as improving timely access to specialized severe asthma services for optimal management. 
		                        		
		                        		
		                        		
		                        	
2.Expert consensus on oral corticosteroid use and tapering in severe asthma management
Joo-Hee KIM ; Noeul KANG ; Sung-Yoon KANG ; Da Woon SIM ; So-Young PARK ; Jong-Sook PARK ; Hyun LEE ; Hyun Jung JIN ; Woo-Jung SONG ; So Ri KIM ; Sang-Heon KIM
Allergy, Asthma & Respiratory Disease 2025;13(1):12-21
		                        		
		                        			
		                        			 Systemic corticosteroids play an essential role in the management of asthma. During acute exacerbation, the short-term use of systemic corticosteroids is recommended. For patients with uncontrolled asthma and severe asthma, long-term and low-dose oral corticosteroids (OCS) have frequently been advocated. However, both short-term and long-term use of systemic corticosteroids carry the risk of adverse events (AEs), including various morbidities and even mortality. Despite recent progress in adult severe asthma management and the availability of new treatment options, the current domestic guidelines for asthma do not provide specific recommendations for oral corticosteroid tapering in patients with severe asthma. Therefore, the task force team of the severe asthma working group in the Korean Academy of Allergy, Asthma, and Clinical Immunology has proposed a tapering protocol for systemic corticosteroid use in severe asthma. This includes practical recommendations for monitoring OCS-related AE, particularly for adrenal insufficiency and osteoporosis, which suggests corticosteroid-sparing strategies that include alternative therapies, modifying treatable traits, timely specialist assessment, and shared decision-making with patients. However, further real-world research and collaboration with doctors from primary and academic institutes, patients, and policymakers are necessary to establish an OCS stewardship approach. This should include realistic OCS-tapering strategies for patients with severe asthma using regular OCS, education, and campaigns for patients, the public, and healthcare providers about the burden of severe asthma, as well as improving timely access to specialized severe asthma services for optimal management. 
		                        		
		                        		
		                        		
		                        	
3.Expert consensus on oral corticosteroid use and tapering in severe asthma management
Joo-Hee KIM ; Noeul KANG ; Sung-Yoon KANG ; Da Woon SIM ; So-Young PARK ; Jong-Sook PARK ; Hyun LEE ; Hyun Jung JIN ; Woo-Jung SONG ; So Ri KIM ; Sang-Heon KIM
Allergy, Asthma & Respiratory Disease 2025;13(1):12-21
		                        		
		                        			
		                        			 Systemic corticosteroids play an essential role in the management of asthma. During acute exacerbation, the short-term use of systemic corticosteroids is recommended. For patients with uncontrolled asthma and severe asthma, long-term and low-dose oral corticosteroids (OCS) have frequently been advocated. However, both short-term and long-term use of systemic corticosteroids carry the risk of adverse events (AEs), including various morbidities and even mortality. Despite recent progress in adult severe asthma management and the availability of new treatment options, the current domestic guidelines for asthma do not provide specific recommendations for oral corticosteroid tapering in patients with severe asthma. Therefore, the task force team of the severe asthma working group in the Korean Academy of Allergy, Asthma, and Clinical Immunology has proposed a tapering protocol for systemic corticosteroid use in severe asthma. This includes practical recommendations for monitoring OCS-related AE, particularly for adrenal insufficiency and osteoporosis, which suggests corticosteroid-sparing strategies that include alternative therapies, modifying treatable traits, timely specialist assessment, and shared decision-making with patients. However, further real-world research and collaboration with doctors from primary and academic institutes, patients, and policymakers are necessary to establish an OCS stewardship approach. This should include realistic OCS-tapering strategies for patients with severe asthma using regular OCS, education, and campaigns for patients, the public, and healthcare providers about the burden of severe asthma, as well as improving timely access to specialized severe asthma services for optimal management. 
		                        		
		                        		
		                        		
		                        	
4.Expert consensus on oral corticosteroid use and tapering in severe asthma management
Joo-Hee KIM ; Noeul KANG ; Sung-Yoon KANG ; Da Woon SIM ; So-Young PARK ; Jong-Sook PARK ; Hyun LEE ; Hyun Jung JIN ; Woo-Jung SONG ; So Ri KIM ; Sang-Heon KIM
Allergy, Asthma & Respiratory Disease 2025;13(1):12-21
		                        		
		                        			
		                        			 Systemic corticosteroids play an essential role in the management of asthma. During acute exacerbation, the short-term use of systemic corticosteroids is recommended. For patients with uncontrolled asthma and severe asthma, long-term and low-dose oral corticosteroids (OCS) have frequently been advocated. However, both short-term and long-term use of systemic corticosteroids carry the risk of adverse events (AEs), including various morbidities and even mortality. Despite recent progress in adult severe asthma management and the availability of new treatment options, the current domestic guidelines for asthma do not provide specific recommendations for oral corticosteroid tapering in patients with severe asthma. Therefore, the task force team of the severe asthma working group in the Korean Academy of Allergy, Asthma, and Clinical Immunology has proposed a tapering protocol for systemic corticosteroid use in severe asthma. This includes practical recommendations for monitoring OCS-related AE, particularly for adrenal insufficiency and osteoporosis, which suggests corticosteroid-sparing strategies that include alternative therapies, modifying treatable traits, timely specialist assessment, and shared decision-making with patients. However, further real-world research and collaboration with doctors from primary and academic institutes, patients, and policymakers are necessary to establish an OCS stewardship approach. This should include realistic OCS-tapering strategies for patients with severe asthma using regular OCS, education, and campaigns for patients, the public, and healthcare providers about the burden of severe asthma, as well as improving timely access to specialized severe asthma services for optimal management. 
		                        		
		                        		
		                        		
		                        	
5.Expert consensus on oral corticosteroid use and tapering in severe asthma management
Joo-Hee KIM ; Noeul KANG ; Sung-Yoon KANG ; Da Woon SIM ; So-Young PARK ; Jong-Sook PARK ; Hyun LEE ; Hyun Jung JIN ; Woo-Jung SONG ; So Ri KIM ; Sang-Heon KIM
Allergy, Asthma & Respiratory Disease 2025;13(1):12-21
		                        		
		                        			
		                        			 Systemic corticosteroids play an essential role in the management of asthma. During acute exacerbation, the short-term use of systemic corticosteroids is recommended. For patients with uncontrolled asthma and severe asthma, long-term and low-dose oral corticosteroids (OCS) have frequently been advocated. However, both short-term and long-term use of systemic corticosteroids carry the risk of adverse events (AEs), including various morbidities and even mortality. Despite recent progress in adult severe asthma management and the availability of new treatment options, the current domestic guidelines for asthma do not provide specific recommendations for oral corticosteroid tapering in patients with severe asthma. Therefore, the task force team of the severe asthma working group in the Korean Academy of Allergy, Asthma, and Clinical Immunology has proposed a tapering protocol for systemic corticosteroid use in severe asthma. This includes practical recommendations for monitoring OCS-related AE, particularly for adrenal insufficiency and osteoporosis, which suggests corticosteroid-sparing strategies that include alternative therapies, modifying treatable traits, timely specialist assessment, and shared decision-making with patients. However, further real-world research and collaboration with doctors from primary and academic institutes, patients, and policymakers are necessary to establish an OCS stewardship approach. This should include realistic OCS-tapering strategies for patients with severe asthma using regular OCS, education, and campaigns for patients, the public, and healthcare providers about the burden of severe asthma, as well as improving timely access to specialized severe asthma services for optimal management. 
		                        		
		                        		
		                        		
		                        	
6.Association Between Plasma Anti-Factor Xa Concentrations and Large Artery Occlusion in Patients With Acute Ischemic Stroke Taking Direct Oral Anticoagulants for Non-valvular Atrial Fibrillation
Dae-Hyun KIM ; Byung-Cheol KWAK ; Byeol-A YOON ; Jae-Kwan CHA ; Jong-Sung PARK ; Min-Sun KWAK ; Kwang-Sook WOO ; Jin-Yeong HAN
Annals of Laboratory Medicine 2024;44(5):459-462
		                        		
		                        		
		                        		
		                        	
7.Association Between Plasma Anti-Factor Xa Concentrations and Large Artery Occlusion in Patients With Acute Ischemic Stroke Taking Direct Oral Anticoagulants for Non-valvular Atrial Fibrillation
Dae-Hyun KIM ; Byung-Cheol KWAK ; Byeol-A YOON ; Jae-Kwan CHA ; Jong-Sung PARK ; Min-Sun KWAK ; Kwang-Sook WOO ; Jin-Yeong HAN
Annals of Laboratory Medicine 2024;44(5):459-462
		                        		
		                        		
		                        		
		                        	
8.Association Between Plasma Anti-Factor Xa Concentrations and Large Artery Occlusion in Patients With Acute Ischemic Stroke Taking Direct Oral Anticoagulants for Non-valvular Atrial Fibrillation
Dae-Hyun KIM ; Byung-Cheol KWAK ; Byeol-A YOON ; Jae-Kwan CHA ; Jong-Sung PARK ; Min-Sun KWAK ; Kwang-Sook WOO ; Jin-Yeong HAN
Annals of Laboratory Medicine 2024;44(5):459-462
		                        		
		                        		
		                        		
		                        	
9.Association Between Plasma Anti-Factor Xa Concentrations and Large Artery Occlusion in Patients With Acute Ischemic Stroke Taking Direct Oral Anticoagulants for Non-valvular Atrial Fibrillation
Dae-Hyun KIM ; Byung-Cheol KWAK ; Byeol-A YOON ; Jae-Kwan CHA ; Jong-Sung PARK ; Min-Sun KWAK ; Kwang-Sook WOO ; Jin-Yeong HAN
Annals of Laboratory Medicine 2024;44(5):459-462
		                        		
		                        		
		                        		
		                        	
10.The prevention and response to infectious diseases in long-term care facilities in Korea: a nationwide survey
Sun Hee NA ; Joong Sik EOM ; Sun Bean KIM ; Hyung Jin YOON ; So Yeon YOO ; Kyeong Sook CHA ; Jong Rim CHOI ; Ji Youn CHOI ; Si Hyeon HAN ; Jin Ju PARK ; Tark KIM ; Jacob LEE
Epidemiology and Health 2024;46(1):e2024084-
		                        		
		                        			 OBJECTIVES:
		                        			Long-term care facilities (LTCFs) are communal environments for patients with chronic diseases or older adults, making them particularly susceptible to significant harm during infectious disease outbreaks. Nonetheless, LTCFs have historically been subject to less stringent infection prevention and control (IPC) mandates. This study aimed to assess the current state of LTCFs and to develop an IPC system tailored for these facilities following the coronavirus disease 2019 (COVID-19) pandemic. 
		                        		
		                        			METHODS:
		                        			We conducted an online survey of 11,366 LTCFs in Korea from December 30, 2022 to January 20, 2023, to evaluate the components of IPC in LTCFs. The infectious diseases targeted for IPC included COVID-19, influenza, and scabies. Additionally, we compared institution-based and home-based long-term care insurance facilities. 
		                        		
		                        			RESULTS:
		                        			Overall, 3,537 (31.1%) LTCFs responded to the survey, comprising 1,819 (51.4%) institution-based and 1,718 (48.6%) home-based facilities. A majority (87.4%, 2,376/2,720) of these facilities experienced COVID-19 outbreaks. However, only 42.2% of home-based facilities, in contrast to 90.6% of institution-based facilities, were equipped to manage concurrent COVID-19 cases. Similarly, while 92.1% of institution-based facilities were capable of managing influenza, only 50.5% of home-based facilities could do the same. The incidence of scabies was significantly higher in institution-based facilities than in home-based ones (26.1 vs. 4.3%). Additionally, 88.7% of institution-based facilities managed scabies cases effectively, compared to only 42.1% of home-based facilities. 
		                        		
		                        			CONCLUSIONS
		                        			Approximately half of the LTCFs had a basic capacity to respond to infectious diseases. However, there were differences in response capabilities between institution-based facilities and home-based facilities. 
		                        		
		                        		
		                        		
		                        	
            
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