1.The impact of alcohol consumption on hearing loss in male workers with a focus on alcohol flushing reaction: the Kangbuk Samsung Cohort Study
Jaehong LEE ; Youshik JEONG ; Jihoon KIM ; Seonghyeon KWON ; Eunhye SEO ; Jinsook JEONG ; Woncheol LEE
Annals of Occupational and Environmental Medicine 2024;36(1):e1-
		                        		
		                        			
		                        			  Despite hearing loss being a prevalent chronic condition, estimated to nearly 20% of the global population by the World Health Organization, the specific association with individual lifestyle factors, particularly alcohol consumption, remains unclear. In South Korea, approximately 80% of the population engages in alcohol consumption, with a notably high prevalence among males, indicating a high-risk drinking pattern. Therefore, this study aimed to assess the correlation between alcohol consumption and hearing loss in male workers, as well as to analyze additional variables such as alcohol flushing reaction, with the intention of improving worker health. The study was conducted from January 2012 to December 2019, targeting 114,114 participants who visited Kangbuk Samsung Hospital Total Healthcare Centers. Data were collected through pure-tone audiometry tests and alcohol-related questionnaire, and statistical analysis was performed using Cox regression analysis. Based on previous studies indicating a potential protective effect of light drinking on hearing loss, this group was designated as the reference. Additionally, stratified analyses were conducted based on the presence of alcohol flushing reaction and different working hours. The hazard ratio (95% confidence interval) for hearing loss was higher in the heavy drinking group (1.23 [1.11–1.37]) compared to the moderate drinking group (1.09 [0.98–1.20]). Stratified analyses revealed a significantly elevated the hazard ratio of hearing loss in groups with alcohol flushing reaction compared to those without this factor. Our study demonstrated that moderate or heavy alcohol consumption in male workers can increase the risk of hearing loss, particularly in those with alcohol flushing reaction. These findings underscore the importance of addressing alcohol-related factors concerning hearing health among male workers.
		                        		
		                        	
2.The impact of alcohol consumption on hearing loss in male workers with a focus on alcohol flushing reaction: the Kangbuk Samsung Cohort Study
Jaehong LEE ; Youshik JEONG ; Jihoon KIM ; Seonghyeon KWON ; Eunhye SEO ; Jinsook JEONG ; Woncheol LEE
Annals of Occupational and Environmental Medicine 2024;36(1):e1-
		                        		
		                        			
		                        			  Despite hearing loss being a prevalent chronic condition, estimated to nearly 20% of the global population by the World Health Organization, the specific association with individual lifestyle factors, particularly alcohol consumption, remains unclear. In South Korea, approximately 80% of the population engages in alcohol consumption, with a notably high prevalence among males, indicating a high-risk drinking pattern. Therefore, this study aimed to assess the correlation between alcohol consumption and hearing loss in male workers, as well as to analyze additional variables such as alcohol flushing reaction, with the intention of improving worker health. The study was conducted from January 2012 to December 2019, targeting 114,114 participants who visited Kangbuk Samsung Hospital Total Healthcare Centers. Data were collected through pure-tone audiometry tests and alcohol-related questionnaire, and statistical analysis was performed using Cox regression analysis. Based on previous studies indicating a potential protective effect of light drinking on hearing loss, this group was designated as the reference. Additionally, stratified analyses were conducted based on the presence of alcohol flushing reaction and different working hours. The hazard ratio (95% confidence interval) for hearing loss was higher in the heavy drinking group (1.23 [1.11–1.37]) compared to the moderate drinking group (1.09 [0.98–1.20]). Stratified analyses revealed a significantly elevated the hazard ratio of hearing loss in groups with alcohol flushing reaction compared to those without this factor. Our study demonstrated that moderate or heavy alcohol consumption in male workers can increase the risk of hearing loss, particularly in those with alcohol flushing reaction. These findings underscore the importance of addressing alcohol-related factors concerning hearing health among male workers.
		                        		
		                        	
3.The impact of alcohol consumption on hearing loss in male workers with a focus on alcohol flushing reaction: the Kangbuk Samsung Cohort Study
Jaehong LEE ; Youshik JEONG ; Jihoon KIM ; Seonghyeon KWON ; Eunhye SEO ; Jinsook JEONG ; Woncheol LEE
Annals of Occupational and Environmental Medicine 2024;36(1):e1-
		                        		
		                        			
		                        			  Despite hearing loss being a prevalent chronic condition, estimated to nearly 20% of the global population by the World Health Organization, the specific association with individual lifestyle factors, particularly alcohol consumption, remains unclear. In South Korea, approximately 80% of the population engages in alcohol consumption, with a notably high prevalence among males, indicating a high-risk drinking pattern. Therefore, this study aimed to assess the correlation between alcohol consumption and hearing loss in male workers, as well as to analyze additional variables such as alcohol flushing reaction, with the intention of improving worker health. The study was conducted from January 2012 to December 2019, targeting 114,114 participants who visited Kangbuk Samsung Hospital Total Healthcare Centers. Data were collected through pure-tone audiometry tests and alcohol-related questionnaire, and statistical analysis was performed using Cox regression analysis. Based on previous studies indicating a potential protective effect of light drinking on hearing loss, this group was designated as the reference. Additionally, stratified analyses were conducted based on the presence of alcohol flushing reaction and different working hours. The hazard ratio (95% confidence interval) for hearing loss was higher in the heavy drinking group (1.23 [1.11–1.37]) compared to the moderate drinking group (1.09 [0.98–1.20]). Stratified analyses revealed a significantly elevated the hazard ratio of hearing loss in groups with alcohol flushing reaction compared to those without this factor. Our study demonstrated that moderate or heavy alcohol consumption in male workers can increase the risk of hearing loss, particularly in those with alcohol flushing reaction. These findings underscore the importance of addressing alcohol-related factors concerning hearing health among male workers.
		                        		
		                        	
4.Analysis of the Effects of the Implementation of Transfusion-Related Education for Nurses at Medical Institutions
Jinsook LIM ; Sae-Rom CHOI ; Chieeun SONG ; Yumi PARK ; Young Ae LIM ; Jun Nyun KIM ; Gye Cheol KWON
Korean Journal of Blood Transfusion 2020;31(3):222-229
		                        		
		                        			Background:
		                        			Nurses play a central role in the process of blood transfusion because they have the closest interactions with patients. Providing nurses with the appropriate knowledge and competency through education can help ensure transfusion safety. This study investigated the effectiveness of the first nationwide transfusion-related education for nurses by analyzing questionnaires for a self-assessment of competency on transfusion-related knowledge before and after the education and general evaluation for the educational program. 
		                        		
		                        			Methods:
		                        			The education program was composed of four lectures and was conducted in seven regions in South Korea. One hundred and ninety-two nurses participated, and the questionnaires for 170 nurses were analyzed. 
		                        		
		                        			Results:
		                        			The participants consisted of 90 nurses (53.0%) from tertiary hospitals, 23 (13.5%) from general hospitals, and 57 (33.5%) from other hospitals. The majority of the participants (103/170, 60.6%) were from hospitals with ≥500 beds, and 69.4% had a work period of ≥10 years. The scores for pre-/post-education self-assessment of competency were as follows: blood components, 3.03/3.73; pretransfusion testing, 2.86/3.64; management of transfusion, 3.18/3.84; and transfusion reactions, 3.11/3.78. In all categories, there was a significant increase in the score after the education program. The majority of participants (99.4%) provided a positive response regarding the necessity of a transfusion-related education program. 
		                        		
		                        			Conclusion
		                        			South Korea’s first attempt at transfusion-related education for nurses showed a strong positive effect by improving participants’ transfusion-related competency. Considering the important role of nurses in blood transfusion, the educational program should continue and be expanded in the future.
		                        		
		                        		
		                        		
		                        	
5.Analysis of the Effects of the Implementation of Transfusion-Related Education for Nurses at Medical Institutions
Jinsook LIM ; Sae-Rom CHOI ; Chieeun SONG ; Yumi PARK ; Young Ae LIM ; Jun Nyun KIM ; Gye Cheol KWON
Korean Journal of Blood Transfusion 2020;31(3):222-229
		                        		
		                        			Background:
		                        			Nurses play a central role in the process of blood transfusion because they have the closest interactions with patients. Providing nurses with the appropriate knowledge and competency through education can help ensure transfusion safety. This study investigated the effectiveness of the first nationwide transfusion-related education for nurses by analyzing questionnaires for a self-assessment of competency on transfusion-related knowledge before and after the education and general evaluation for the educational program. 
		                        		
		                        			Methods:
		                        			The education program was composed of four lectures and was conducted in seven regions in South Korea. One hundred and ninety-two nurses participated, and the questionnaires for 170 nurses were analyzed. 
		                        		
		                        			Results:
		                        			The participants consisted of 90 nurses (53.0%) from tertiary hospitals, 23 (13.5%) from general hospitals, and 57 (33.5%) from other hospitals. The majority of the participants (103/170, 60.6%) were from hospitals with ≥500 beds, and 69.4% had a work period of ≥10 years. The scores for pre-/post-education self-assessment of competency were as follows: blood components, 3.03/3.73; pretransfusion testing, 2.86/3.64; management of transfusion, 3.18/3.84; and transfusion reactions, 3.11/3.78. In all categories, there was a significant increase in the score after the education program. The majority of participants (99.4%) provided a positive response regarding the necessity of a transfusion-related education program. 
		                        		
		                        			Conclusion
		                        			South Korea’s first attempt at transfusion-related education for nurses showed a strong positive effect by improving participants’ transfusion-related competency. Considering the important role of nurses in blood transfusion, the educational program should continue and be expanded in the future.
		                        		
		                        		
		                        		
		                        	
6.Evaluation of the Automated Cross-Matching Instrument, ORTHO VISION, for Use in Blood Banks
Mosae KOO ; Jinsook LIM ; Seon Yung KIM ; Ji Myung KIM ; Sun Hoe KOO ; Gye Cheol KWON
Laboratory Medicine Online 2019;9(4):218-223
		                        		
		                        			
		                        			BACKGROUND: Automated systems are used widely for pre-transfusion tests in blood banks, in an attempt to reduce effort and human error. We evaluated the clinical performance of an automated blood bank system, ORTHO VISION (Ortho-Clinical Diagnostics, Switzerland), for blood cross-matching. METHODS: Saline cross-matching was performed for 93 tests using 56 samples. Coombs cross-matching was performed for 400 tests using 166 samples. Saline cross-matching was compared for the automated ORTHO VISION and manual tube methods. Coombs cross-matching was compared for the automated ORTHO VISION and manual column agglutination technique (CAT) methods. The evaluation of 32 antibody-positive samples using the automated ORTHO VISION and manual CAT methods was compared by performing 97 cross-matching tests. Additionally, the ORTHO VISION efficiency and carryover were evaluated. RESULTS: The concordance rate of the saline cross-matching results between the manual method and automated ORTHO VISION was 100%. The concordance rate of coombs cross-matching results between manual CAT and automated ORTHO VISION was 97.9%. The concordance rate of cross-matching for antibody positive samples between manual CAT and the automated ORTHO VISION was 97.9%. Coombs cross-matching was efficient using ORTHO VISION, whereas saline cross-matching was efficient using the tube manual method. CONCLUSIONS: ORTHO VISION showed reliable results for cross-matching and was more efficient than manual CAT for coombs cross-matching. Thus, ORTHO VISION can be used for pre-transfusion tests in blood banks.
		                        		
		                        		
		                        		
		                        			Agglutination
		                        			;
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Automation
		                        			;
		                        		
		                        			Blood Banks
		                        			;
		                        		
		                        			Cats
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Methods
		                        			
		                        		
		                        	
7.Experiencing Coercive Control in Female Victims of Dating Violence
Journal of Korean Academy of Nursing 2019;49(1):46-58
		                        		
		                        			
		                        			BACKGROUND: Dating violence refers to violence occurring between people in an intimate relationship. Forms of dating violence are often categorized into physical, psychological, and sexual violence, and most existing literature has followed this frame. However, few studies have focused on the phenomenon of living under the perpetrator's coercive control in victims of dating violence, although those experiences are known to be signs of severe forms of violence later on. PURPOSE: The purpose of this study was to explore the experiences of being coercively controlled in female victims who had experienced dating violence. METHODS: For this study, in-depth interviews were conducted with a total of 14 female victims, and all interviews were audio-recorded and transcribed. The data were analyzed using the phenomenological analysis method suggested by Colaizzi. RESULTS: Three themes were derived in chronological order: idealizing the relationship (period of potential control), facing severer tyranny (period of coercive control), and escaping from the unending trap (period of post-control). The results showed that the victims experienced perpetrators' control with specific patterns. The perpetrators' controlling behaviors were invisible, literally benevolent, at the beginning; however, severe forms of violence seemed to appear as their relationship deepened and the perpetrators failed to control the victims. CONCLUSION: Findings from this study presented vivid experiences of female victims who needed help and care. Hopefully, the results can benefit in terms of developing evidence-based prevention strategies for victims as well as assessing the risks of severe forms of dating violence, such as physical attack or murder.
		                        		
		                        		
		                        		
		                        			Crime Victims
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Homicide
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intimate Partner Violence
		                        			;
		                        		
		                        			Methods
		                        			;
		                        		
		                        			Physical Abuse
		                        			;
		                        		
		                        			Qualitative Research
		                        			;
		                        		
		                        			Sex Offenses
		                        			;
		                        		
		                        			United Nations
		                        			;
		                        		
		                        			Violence
		                        			
		                        		
		                        	
8.Performance Evaluation of the CRE2 Reagent from Siemens for Serum Creatinine Measurement.
Hyunjin KIM ; Jinsook LIM ; Sun Hoe KOO ; Jimyung KIM ; Seon Young KIM ; Gye Cheol KWON
Laboratory Medicine Online 2019;9(1):6-11
		                        		
		                        			
		                        			BACKGROUND: For creatinine measurement, the enzymatic method is known to be more accurate than the Jaffe method; however, the latter is still widely used. We evaluated the performance of the CRE2 reagent (Siemens Healthcare Diagnostics Inc., USA), which uses a modified Jaffe method. METHODS: Three quality control standards were used for precision evaluations of CRE2 on Dimension VISTA 500 instrument (Siemens). Moreover, the linearity and carryover characteristics were assessed. Sixty-eight creatinine results obtained using the CRE2 and ECREA (enzymatic) reagents (Siemens) were compared with those obtained using the L-CRE (enzymatic) reagent (Shinyang Diagnostics, Korea). The accuracy of CRE2, ECREA, and L-CRE was evaluated using a standard reference material. RESULTS: The CV of within-run (0.7–2.4%), between-run (0.4–1.7%), between-day precision (0.7–0.9%) for three standards, and total CV for medium (1.6%) and high levels (1.3%) satisfied the analytical goal. The linearity for CRE2 was excellent (R2=0.999). Comparisons of CRE2 and ECREA to L-CRE were well correlated (r=0.996 and 0.997, respectively). In comparison with L-CRE, 5 CRE2 results and 15 ECREA results exceeded minimum bias goal (5.1%) in samples with creatinine levels of >1 mg/dL. The carryover rate was −0.04%. In terms of accuracy, the percent bias values of CRE2, ECREA, and L-CRE were 7.4, −6.4, and −3.4, respectively, for low level; and 3.9, −1.5, and 0.7, respectively, for high level. CONCLUSIONS: For creatinine measurements, the CRE2 reagent showed good performance. It can be used in the diagnosis, treatment monitoring, and risk assessment of kidney diseases.
		                        		
		                        		
		                        		
		                        			Bias (Epidemiology)
		                        			;
		                        		
		                        			Creatinine*
		                        			;
		                        		
		                        			Delivery of Health Care
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Indicators and Reagents
		                        			;
		                        		
		                        			Kidney Diseases
		                        			;
		                        		
		                        			Methods
		                        			;
		                        		
		                        			Quality Control
		                        			;
		                        		
		                        			Risk Assessment
		                        			
		                        		
		                        	
9.Comparison of Red Blood Cell, White Blood Cell and Differential Counts between UF-5000 System and Manual Method
Mo Sae KOO ; Jinsook LIM ; Seon Young KIM ; Sun Hoe KOO ; Gye Cheol KWON
Journal of Laboratory Medicine and Quality Assurance 2019;41(3):172-178
		                        		
		                        			
		                        			BACKGROUND: Analysis of body fluids provides important information for assessing various medical conditions. We aimed to validate the analytical and diagnostic performance of the Sysmex UF-5000 (Sysmex, Japan) system for the analysis of different body fluids. METHODS: Eighty body fluid samples were analyzed using the UF-5000 system in the body fluid mode and light microscopy. Body fluids included ascitic, pleural, and cerebrospinal fluid (CSF), as well as other fluid samples. RESULTS: A comparison between the UF-5000 system and manual counting demonstrated good correlations with regard to red (r=0.6555) and white blood cell (r=0.9666) counts. The UF-5000 system also demonstrated good performance for differential cell counting (r=0.9028). CSF particularly showed a good correlation. CONCLUSIONS: The use of the UF-5000 system for cell counting and differential analysis of body fluid samples might be an effective and automated alternative to chamber counting in laboratory routine analysis, thereby enhancing laboratory workflow and clinical effectiveness.
		                        		
		                        		
		                        		
		                        			Automation
		                        			;
		                        		
		                        			Body Fluids
		                        			;
		                        		
		                        			Cell Count
		                        			;
		                        		
		                        			Cerebrospinal Fluid
		                        			;
		                        		
		                        			Erythrocytes
		                        			;
		                        		
		                        			Leukocytes
		                        			;
		                        		
		                        			Methods
		                        			;
		                        		
		                        			Microscopy
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
10.Experiencing Coercive Control in Female Victims of Dating Violence
Journal of Korean Academy of Nursing 2019;49(1):46-58
		                        		
		                        			 BACKGROUND:
		                        			Dating violence refers to violence occurring between people in an intimate relationship. Forms of dating violence are often categorized into physical, psychological, and sexual violence, and most existing literature has followed this frame. However, few studies have focused on the phenomenon of living under the perpetrator's coercive control in victims of dating violence, although those experiences are known to be signs of severe forms of violence later on.PURPOSE: The purpose of this study was to explore the experiences of being coercively controlled in female victims who had experienced dating violence.
		                        		
		                        			METHODS:
		                        			For this study, in-depth interviews were conducted with a total of 14 female victims, and all interviews were audio-recorded and transcribed. The data were analyzed using the phenomenological analysis method suggested by Colaizzi.
		                        		
		                        			RESULTS:
		                        			Three themes were derived in chronological order: idealizing the relationship (period of potential control), facing severer tyranny (period of coercive control), and escaping from the unending trap (period of post-control). The results showed that the victims experienced perpetrators' control with specific patterns. The perpetrators' controlling behaviors were invisible, literally benevolent, at the beginning; however, severe forms of violence seemed to appear as their relationship deepened and the perpetrators failed to control the victims.
		                        		
		                        			CONCLUSION
		                        			Findings from this study presented vivid experiences of female victims who needed help and care. Hopefully, the results can benefit in terms of developing evidence-based prevention strategies for victims as well as assessing the risks of severe forms of dating violence, such as physical attack or murder. 
		                        		
		                        		
		                        		
		                        	
            
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