Objective:To explore the safety and efficacy of ultrasound-assisted facial filler injection, based on the anatomy of facial vessels to prevent intravascular embolization.Methods:From Jan. 2019 to Sep. 2020, 142 patients were treated with facial soft-tissue filler injection (mean age, 39.7 years; 131 female and 11 male). According to the patients＇ own will, autologous fat or hyaluronic acid was applied respectively. When injecting, the assistant could press over the periorbital artery to temporarily occlude the artery, confirmed with Doppler ultrasound, thus reduced the risk of intravascular embolization, and carefully injected with minimal pressure and tiny amount.Results:A total of 142 patients were enrolled in the study, and 54 patients were treated with autologous fat grafting, while 88 patients were injected with hyaluronic acid. The injection sites included forehead, temple, glabella, nasal root, tear trough, nasolabial fold, cheek, chin, and lips. Facial rejuvenation improvement was satisfied with a smooth contour and proper augmentation. No vascular embolization occurred. 9 patients received a second or third round fat grafting to achieve better outcome. Follow-up duration ranged from 1 month to 6 months.Conclusions:With ultrasound assistant, digital pressure over the orbital artery could temporarily occlude the artery and may reduce the risk of intravascular embolization. The simple technique may add a significant benefit with no additional cost or risk to the patients.

Objective: To explore the clinical effect of cervico-acromial fasciocutaneous flap based on the supraclavicular artery as a method for face and neck reconstruction. Methods: From Oct 1990 to June 2014, 17 patients, with the age range of 7 to 51 years, suffering from cicatricle contractures of neck or facial defect, were treated with cervico-acromial fascicutaneous flaps. 29 flaps were used in 12 patients bilaterally or multiply. The donor sites of 2 patients were closed by skin graft; while in the rest 15 patients, the donor sites were closed by expanded flaps. Results: All the 29 flaps were survived, with satisfactory color and texture. Hematoma occurred in 1 case after tissue expander implantation, but the flap was successfully expanded after evacuation of hematoma. The size of flaps ranged from 15 cm×7 cm to 35 cm×15 cm. 10 patients completed 6 months follow-up, and presented with satisfactory appearance and better functional results. Conclusions Cervico-acromial fascicutaneous flap based on the supraclavicular artery is an good choice for reconstruction of neck and facial defects.

Objective To analyze the results of inspection certification on malaria elimination in Baise City,and summarize the experiences of malaria elimination at a prefecture level. Methods According to Evaluation Schemes of Malaria Elimination (2014 edition)and Municipal Evaluation Schemes of Malaria Elimination in Guangxi(2016 edition),the malaria elimination work in Baise City was evaluated. In addition,2 counties(cities,districts)in the administrative region of Baise City were ran-domly selected for review assessment. Then the assessment and certification results were analyzed. Results The score of evalua-tion on malaria elimination in Baise City was 95.80,and the scores of review in Tiandong County and Jingxi City were 94.70 and 90.60,respectively. According to the weight of the three scores,namely 0.4,0.3,0.3,the final score of malaria elimination in Baise City was 93.91,which reached the national standards of malaria elimination score(more than 85). Conclusions Baise City has passed the inspection certification of malaria elimination by the authority of Guangxi Zhuang Autonomous Region. How-ever,the malaria monitoring post-elimination still should continue to consolidate the elimination achievements.

Objective To understand the schistosomiasis epidemic and control history in Jingxi City,so as to provide the ev-idence for improving the future work. Methods The data of schistosomiasis prevention and control work were collected and ana-lyzed comprehensively in Jingxi City from 1956-2015. Results From 1956,the schistosomiasis prevention and control work car-ried out,and in 1985,Jingxi City reached the standard of schistosomiasis transmission interrupted and no local schistosome in-fected residents and livestock were found for 36 years. In May 2016,the city reached the national standard of Schistosomiasis Elimination Assessment Review. The cumulative number of schistosomiasis detection of residents was 348801 person-times, and 10434 schistosomiasis patients were found. The cumulative number of schistosomiasis detection of cattle was 20674 head-times,and 590 schistosome infected cattle were found. The cumulative schistosomiasis treatment number of residents was 18739 per-son-times,and 512 cattle were treated. The cumulative detection area with Oncomelania hupensis was 65213.25 hm2 ,and 353.80 hm2 area with O. hupensis snails was found. Conclusions Jingxi City has reached the standard of schistosomiasis elimi-nation,but there is still recurrence of O. hupensis snails,and the imported infection source exists. Therefore,we should strength-en the monitoring of floating population.

Objective To analyze the assessment results and summary the work experience of malaria elimination in Baise City. Methods According to The malaria elimination evaluation schemes of Guangxi(2014 edition),the examination and evaluation of malaria elimination were carried out and all the results were analyzed in 12 counties(county?level city or district) of Baise City from 2014 to 2015. Results Since 2009,there were no local malaria cases and imported secondary cases in Baise City for the 6 consecutive years,and the detailed data were collected and the self?assessment reports of malaria elimination were written in all the counties. There was no omission or delay of malaria case reports in the 12 counties. The highest score of the ex?amination and evaluation was 96.58 points,the lowest was 90.76 points,and the average was 93.77 points. The biggest impact on the evaluation scores was“on?site examination”. Conclusion All the 12 counties(county?level city or district)of Baise City have passed the municipal examination and evaluation of malaria elimination,and the key of next work is malaria monitoring, timely finding and treating the imported malaria patients,and to guarantee no imported secondary cases.

Objective To explore the law and distribution characteristics of malaria prevalence in Pingguo County,Guangxi Zhuang Autonomous Region,so as to provide the evidence for formulating the targeted control strategy and measures after malar?ia elimination. Methods The data of malaria epidemic situation in Pingguo County from 1951 to 2014 were collected and ana?lyzed with the retrospective epidemiological method. Results From 1951 to 2014,there were 71 365 malaria cases reported in the county. The malaria incidence dropped from 429.43/10 000 in 1960 to 0 in 1993. Since 2002,there was no local endogenous infection case reported. In 1993,this county achieved the standard of malaria elimination basically,and in 2014,passed the ex?amination and evaluation of malaria elimination. Conclusions In Pingguo County,the comprehensive malarial control strategy is effective in different stages. In the future,the monitoring of mobile population and dealing with imported malaria cases timely is the key of consolidation of malaria control achievements.

Objective To compare the cumulative rate of HBeAg seroconversion in HBeAg positive chronic Hepatitis B patients treated with telbivudine and entecavir after Propensity Score Matching.Methods CHB patients who accepted telbivudine or entecavir from Dec 2009 to May 2014 were retrospectively collected.PSM function of SPSS software was conducted to reduce confounding bias between the groups.And then survival analysis was performed for the matched data.Results 56 pairs of patients were successfully matched.The 2-year cumulative rate of HBeAg seroconversion were 28.6％ and 14.8％ in the telbivudine group and entecavir group,which were 42.0％ and 39.3％ in the fourth year respectively.Cox regression analysis revealed that telbivudine therapy,low HBeAg level at baseline were independent predict factors of HBeAg seroconversion(P ＜ 0.05).Conclusions The balance of covariates may be achieved through PSM.The 2-year cumulative rate of HBeAg seroconversion in the telbivudine group is higher than entecavir group,while they are similar in the 4th year.

ObjectiveTo explore the efficacy and safety of percutaneous antegrade stenting in the treatment of ureteral obstruction after renal transplantation.MethodsWe retrospectively reviewed 11patients with renal graft ureteral obstruction (2 cases of acute obstruction and 9 cases of chronic obstruction) from March 2009 to March 2011.The etiology of the obstruction was renal graft-ureter-bladder anastomotic stricture in 5 cases,stone obstruction in 2 cases,and undetermined in 4 cases.Renal graft and collecting system were examined by ultrasonography preoperatively to select suitable puncture position,and then ureteropyelography was performed under X-ray guidance.When the obstruction location was clear,the urology guidewire was implanted to the bladder by needle,and then guidewire was released by cystoscopy.Ureteral stent was implanted along the guidewire,and upper ureteral stents was observed under X-ray. After removal of guidewire,the stent location was confirmed once again.The renal pelvis fistula drainage lasted for 1-2 weeks,and ureteral stent to 6 months to one year.Ultrasound and renal function were tested after 1week,1month,3 months and 6 months,and then every six months.ResultsOperation was done successfully in 10 patients,and failed in one case due to a long segment of ureteral stenosis.The operating time of ureteral stent implantation was 54±27 min.Serum creatinine of patients was reduced from preoperative 326±147 to postoperative 89±49 μmol/L.During a follow-up period of 6 to 27 months,no complications occurred.ConclusionPercutaneous antegrade stenting in the treatment of ureteral obstruction after renal transplantation is safe and effective.

Objective To explore the correlation between post-transplant glomerular filtration rate (GFR) in 1 year and long-term graft survival in renal transplant patients.Methods The clinical data of 334 patients who received their cadaveric kidney transplantations between November 1994 and October 2004 were analyzed retrospectively.According to the GFR at one year after transplant operation, normal GFR group was defined as GFR more than or equal to 1.083 ml/s, while patients whose GFR less than 1.083 ml/s were fallen into abnormal GFR group.Cockeroft-Gault (C-G) formula was used to compare the difference in the renal function between the two groups.Kaplan-Meier assay was used to compare the difference in the allograft survival between the two groups in the functional renal allograft or the non-functional renal allograft.The correlativity of GFR level at the first year and the GFR level at the 5th year was analyzed.Results The GFR level at the first year after transplantation was proportional to the graft survival time of the kidney.Five and ten years after transplantation, the renal transplantation long-term survival rate in the normal renal function groups was significantly higher than in the abnormal renal function groups (P＜0.05).As compared with the GFR level at the first year after transplantation, the changes in amplitude of GFR level at the 5th year after transplantation was (0.080 ±0.248) ml/s, and the descent had a positive correlation with GFR level at the 5th year after transplantatioa Conclusion GFR level at the first year after transplantation predicts long-term renal functioa The higher of GFR level at the first year, the higher of GFR level at the 5th year.

Objective To investigate the effects of hemodialysis (HD) and peritoneal dialysis (PD) on the complications and outcomes after renal transplantation. Methods Clinical data of 402 renal transplant recipients maintained on dialysis for more than 3 months were retrospectively studied and divided into 2 groups: HD group(n=303)and PD group(n=99). Among them, 345 recipients were followed up for an average of (30.2±15.2) months. The impact of HD and PD on the acute rejection, delayed graft function (DGF), infection, chronic rejection and the graft and patient survival rates were analyzed. Results The mean dialysis duration was significantly longer in PD group and the hepatitis B infection rate was significantly higher in HD group. There were no signiticant differences between the HD and PD groups in regarding to primary disease for end-stage renal disease, age, gender, blood pressure, hemoglobin, HLA match, hot and cold ischemia time, and hepatitis C vires infection. The incidence of DGF, acute and chronic rejection, and cytomegalovirus and other infections between HD and PD groups were not significantly different. However, the graft loss happened more frequently in hepatatis B patients than that in non hepatitis B patients (19.23% vs 8.86%, P=0.021), and the post-transplant infection ocurred less in non hepatits B patients with PD. The acute rejection episodes were higher in HD patients who received pretransplant dialysis for more than 12 months (P<0.05). The overall recipients survival rates of HD and PD groups were similar (1-year: HD 94.34%, PD 91.25%;5-year: HD 92.83%, PD 90%), and the same as the graft survival rates in HD and PD groups (1-year: HD 93.21%, PD 96.25%;5-year: HD 87.17%, PD 91.25%). Conclusions The influences of PD and HD on the complications after renal transplantaton, 1-year and S-year recipients and graft survival rates are similar, so both HD and PD can be chosen as the pretransplant dialysis modality. As the incidence of acute rejection increases with time in HD, it is better to shorten the time of pretransplant dialysis to decrease the complication.