1.Seropositive Neuromyelitis Optica imitating an Intramedullary Cervical Spinal Cord Tumor: Case Report and Brief Review of the Literature.
Peter Yat Ming WOO ; Jennifer Hiu Fung CHIU ; Kar Ming LEUNG ; Kwong Yau CHAN
Asian Spine Journal 2014;8(5):684-688
		                        		
		                        			
		                        			A 44-year-old woman with progressive cervical myelopathy and central cord syndrome was noted to have an extensive cervical intramedullary contrast-enhancing lesion on magnetic resonance imaging (MRI). The lesion resembled a spinal astrocytoma or ependymoma that required surgical intervention. She was subsequently diagnosed to have neuromyelitis optica (NMO), a rare idiopathic inflammatory demyelinating disorder, when the clinical examination revealed left optic atrophy. This was confirmed by a test showing seropositivity for NMO-immunoglobulin (IgG). Disease control was achieved with corticosteroids and immunosuppressive therapy. We report a rare case of a patient with NMO who had MRI features that could have easily led to the condition being misdiagnosed as a spinal cord tumor. The importance of careful history taking, awareness of typical radiological findings and the usefulness of serum NMO-IgG as a diagnostic tool are emphasized.
		                        		
		                        		
		                        		
		                        			Adrenal Cortex Hormones
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Astrocytoma
		                        			;
		                        		
		                        			Central Cord Syndrome
		                        			;
		                        		
		                        			Demyelinating Diseases
		                        			;
		                        		
		                        			Ependymoma
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Neuromyelitis Optica*
		                        			;
		                        		
		                        			Optic Atrophy
		                        			;
		                        		
		                        			Spinal Cord Diseases
		                        			;
		                        		
		                        			Spinal Cord Neoplasms*
		                        			
		                        		
		                        	
            
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