3.Factors associated with surgical morbidity of primary debulking in epithelial ovarian cancer
Emre GÜNAKAN ; Yusuf Aytaç TOHMA ; Mehmet TUNÇ ; Hüseyin AKILLI ; Hanifi ŞAHIN ; Ali AYHAN
Obstetrics & Gynecology Science 2020;63(1):64-71
Intraoperative and postoperative complications that occurred within 30 days after the surgery and factors that affect morbidity were considered.RESULTS: The study involved 359 patients. Forty-six intraoperative complications occurred in 42 (11.6%) patients. Advanced stage and cancer antigen level of 125 were independently and significantly associated with operative complications (hazard ratio [HR], 1.66; 95% confidence interval [CI], 1.01–2,73; P=0.044, and HR, 1.47; 95% CI, 1.05–2.06; P=0.025, respectively). The need for intensive care unit admission was significantly higher in patients with intraoperative complications (28.6% vs. 8.8%, P=0.001). Intraoperative and postoperative complication rates were significantly higher in extended surgery than in standard surgery (18.9%vs. 8.5%, P=0.005 and 38.7% vs. 10.9%, P < 0.001, respectively). Intraoperative and postoperative transfusion need, hospital stay duration, and chemotherapy start day were also significantly higher in extended surgery than in standard surgery. Hundred postoperative complications occurred in 70 patients. Age, extended surgery, presence of ascites, and presence of operative complications were independently and significantly associated with postoperative complications.CONCLUSION: Morbidity of extensive surgical approach should be kept in mind in ovarian cancer surgery aimed at leaving no residual tumor. Patient-based management with an appropriate preoperative evaluation may avoid morbidity of extended/extensive surgical approaches.]]>
Ascites
;
Drug Therapy
;
Humans
;
Intensive Care Units
;
Intraoperative Complications
;
Length of Stay
;
Neoplasm, Residual
;
Ovarian Neoplasms
;
Postoperative Complications
4.Pain management strategies in penile implantation.
Jeffrey L ELLIS ; Andrew M HIGGINS ; Jay SIMHAN
Asian Journal of Andrology 2020;22(1):34-38
The opioid epidemic continues to be a serious public health concern. Many have pointed to prescription drug misuse as a nidus for patients to become addicted to opioids and as such, urologists and other surgical subspecialists must critically define optimal pain management for the various procedures performed within their respective disciplines. Controlling pain following penile prosthesis implantation remains a unique challenge for urologists, given the increased pain patients commonly experience in the postoperative setting. Although most of the existing urological literature focuses on interventions performed in the operating room, there are many studies that examine the role of preoperative adjunctive pain medicine in diminishing postoperative narcotic requirements. There are relatively few studies looking at postoperative strategies for managing pain in prosthetic surgery with follow-up past the immediate hospitalization. This review assess the various strategies employed for managing pain following penile implantation through the lens of the current state of the opioid crisis, thus examining how urologists can responsibly treat pain without contributing to the growing threat of opioid addiction.
Analgesics/therapeutic use*
;
Analgesics, Opioid/therapeutic use*
;
Anesthetics, Local/therapeutic use*
;
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use*
;
Cyclooxygenase 2 Inhibitors/therapeutic use*
;
Gabapentin/therapeutic use*
;
Humans
;
Intraoperative Care
;
Male
;
Nerve Block/methods*
;
Opioid Epidemic
;
Pain Management/methods*
;
Pain, Postoperative/therapy*
;
Penile Implantation/methods*
;
Pregabalin/therapeutic use*
;
Preoperative Care
5.Anesthetic considerations for lung transplantation
Anesthesia and Pain Medicine 2019;14(3):241-248
Since the first lung transplantation, developments in surgical techniques, immunosuppressants, preservation solutions, monitoring devices, anesthetic agents, and drugs and devices for hemodynamic support have resulted in improved survival rates after lung transplantation. Lung transplantation is a high-risk procedure and end-stage lung disease is frequently accompanied by compromised cardiopulmonary function. Therefore, a highly trained cardiothoracic anesthesiologist is required during the procedure. As various factors related to anesthesia may have important effects on the prognosis of the patient after the lung transplantation, an anesthesiologist must not only be familiar with the use of various medications and monitoring devices, but also understand the patient's pathophysiology and the surgical procedure.
Anesthesia
;
Anesthetics
;
Hemodynamics
;
Humans
;
Immunosuppressive Agents
;
Intraoperative Care
;
Lung Diseases
;
Lung Transplantation
;
Lung
;
Prognosis
;
Reperfusion Injury
;
Survival Rate
6.Lumbar Lordosis of Spinal Stenosis Patients during Intraoperative Prone Positioning.
Su Keon LEE ; Seung Hwan LEE ; Kyung Sub SONG ; Byung Moon PARK ; Sang Youn LIM ; Geun JANG ; Beom Seok LEE ; Seong Hwan MOON ; Hwan Mo LEE
Clinics in Orthopedic Surgery 2016;8(1):65-70
BACKGROUND: To evaluate the effect of spondylolisthesis on lumbar lordosis on the OSI (Jackson; Orthopaedic Systems Inc.) frame. Restoration of lumbar lordosis is important for maintaining sagittal balance. Physiologic lumbar lordosis has to be gained by intraoperative prone positioning with a hip extension and posterior instrumentation technique. There are some debates about changing lumbar lordosis on the OSI frame after an intraoperative prone position. We evaluated the effect of spondylolisthesis on lumbar lordosis after an intraoperative prone position. METHODS: Sixty-seven patients, who underwent spinal fusion at the Department of Orthopaedic Surgery of Gwangmyeong Sungae Hospital between May 2007 and February 2012, were included in this study. The study compared lumbar lordosis on preoperative upright, intraoperative prone and postoperative upright lateral X-rays between the simple stenosis (SS) group and spondylolisthesis group. The average age of patients was 67.86 years old. The average preoperative lordosis was 43.5degrees (+/- 14.9degrees), average intraoperative lordosis was 48.8degrees (+/- 13.2degrees), average postoperative lordosis was 46.5degrees (+/- 16.1degrees) and the average change on the frame was 5.3degrees (+/- 10.6degrees). RESULTS: Among all patients, 24 patients were diagnosed with simple spinal stenosis, 43 patients with spondylolisthesis (29 degenerative spondylolisthesis and 14 isthmic spondylolisthesis). Between the SS group and spondylolisthesis group, preoperative lordosis, intraoperative lordosis and postoperative lordosis were significantly larger in the spondylolisthesis group. The ratio of patients with increased lordosis on the OSI frame compared to preoperative lordosis was significantly higher in the spondylolisthesis group. The risk of increased lordosis on frame was significantly higher in the spondylolisthesis group (odds ratio, 3.325; 95% confidence interval, 1.101 to 10.039; p = 0.033). CONCLUSIONS: Intraoperative lumbar lordosis on the OSI frame with a prone position was larger in the SS patients than the spondylolisthesis patients, which also produced a larger postoperative lordosis angle after posterior spinal fusion surgery. An increase in lumbar lordosis on the OSI frame should be considered during posterior spinal fusion surgery, especially in spondylolisthesis patients.
Aged
;
Aged, 80 and over
;
Female
;
Humans
;
Intraoperative Care/*methods
;
Lumbar Vertebrae/*surgery
;
Male
;
Middle Aged
;
Postoperative Complications/*prevention & control
;
Posture/physiology
;
Prone Position/*physiology
;
Retrospective Studies
;
Spinal Stenosis/*surgery
;
Spondylolisthesis/*surgery
7.The First Experiences of Robotic Single-Site Cholecystectomy in Asia: A Potential Way to Expand Minimally-Invasive Single-Site Surgery?.
Sung Hwan LEE ; Myung Jae JUNG ; Ho Kyoung HWANG ; Chang Moo KANG ; Woo Jung LEE
Yonsei Medical Journal 2015;56(1):189-195
PURPOSE: Herein, we firstly present the robotic single-site cholecystectomy (RSSC) as performed in Asia and evaluate whether it could overcome the limitations of conventional laparoscopic single-site cholecystectomy. MATERIALS AND METHODS: From October 2013 to November 2013, RSSC for benign gallbladder (GB) disease was firstly performed consecutively in five patients. We evaluated these early experiences of RSSC and compared factors including clinicopathologic factors and operative outcomes with our initial cases of single-fulcrum laparoscopic cholecystectomy (SFLC). RESULTS: Four female patients and one male patient underwent RSSC. Neither open conversion nor bile duct injury or bile spillage was noted during surgery. In comparisons with SFLC, patient-related factors in terms of age, sex, Body Mass Index, diagnosis, and American Society of Anesthesiologist score showed no significant differences between two groups. There were no significant differences in the operative outcomes regarding intraoperative blood loss, bile spillage during operation, postoperative pain scale values, postoperative complications, and hospital stay between the two groups (p<0.05). Actual dissection time (p=0.003) and total operation time (p=0.001) were significantly longer in RSSC than in SFLC. There were no drain insertion or open conversion cases in either group. CONCLUSION: RSSC provides a comfortable environment and improved ergonomics to laparoscopic single-site cholecystectomy; however, this technique needs to be modified to allow for more effective intracorporeal movement. As experience and technical innovations continue, RSSC will soon be alternative procedure for well-selected benign GB disease.
Adult
;
Asia
;
Blood Loss, Surgical
;
Cholecystectomy, Laparoscopic/instrumentation/*methods
;
Dissection
;
Female
;
Fluorescence
;
Gallbladder Diseases/surgery
;
Humans
;
Intraoperative Care
;
Male
;
Middle Aged
;
Minimally Invasive Surgical Procedures/instrumentation/*methods
;
Operative Time
;
Robotics/instrumentation/*methods
8.The Effects of Oral Atenolol or Enalapril Premedication on Blood Loss and Hypotensive Anesthesia in Orthognathic Surgery.
Na Young KIM ; Young Chul YOO ; Duk Hee CHUN ; Hye Mi LEE ; Young Soo JUNG ; Sun Joon BAI
Yonsei Medical Journal 2015;56(4):1114-1121
PURPOSE: The aim of this study was to evaluate the effects of premedication with oral atenolol or enalapril, in combination with remifentanil under sevoflurane anesthesia, on intraoperative blood loss by achieving adequate deliberate hypotension (DH) during orthognathic surgery. Furthermore, we investigated the impact thereof on the amount of nitroglycerin (NTG) administered as an adjuvant agent. MATERIALS AND METHODS: Seventy-three patients undergoing orthognathic surgery were randomly allocated into one of three groups: an angiotensin converting enzyme inhibitor group (Group A, n=24) with enalapril 10 mg, a beta blocker group (Group B, n=24) with atenolol 25 mg, or a control group (Group C, n=25) with placebo. All patients were premedicated orally 1 h before the induction of anesthesia. NTG was the only adjuvant agent used to achieve DH when mean arterial blood pressure (MAP) was not controlled, despite the administration of the maximum remifentanil dose (0.3 microg kg-1min-1) with sevoflurane. RESULTS: Seventy-two patients completed the study. Blood loss was significantly reduced in Group A, compared to Group C (adjusted p=0.045). Over the target range of MAP percentage during DH was significantly higher in Group C than in Groups A and B (adjusted p-values=0.007 and 0.006, respectively). The total amount of NTG administered was significantly less in Group A than Group C (adjusted p=0.015). CONCLUSION: Premedication with enalapril (10 mg) combined with remifentanil under sevoflurane anesthesia attenuated blood loss and achieved satisfactory DH during orthognathic surgery. Furthermore, the amount of NTG was reduced during the surgery.
Administration, Oral
;
Adrenergic beta-Antagonists/administration & dosage/*pharmacology
;
Adult
;
Aged
;
*Anesthesia, Inhalation
;
Atenolol/administration & dosage/*pharmacology
;
Blood Loss, Surgical
;
Blood Pressure/drug effects
;
Cardiac Output/drug effects
;
Double-Blind Method
;
Enalapril/administration & dosage/*pharmacology
;
Female
;
Heart Rate/drug effects
;
Humans
;
Intraoperative Care
;
Male
;
Methyl Ethers/*administration & dosage
;
Middle Aged
;
*Orthognathic Surgical Procedures
;
Piperidines/*administration & dosage
;
*Premedication
;
Treatment Outcome
9.Controversies in borderline ovarian tumors.
Seok Ju SEONG ; Da Hee KIM ; Mi Kyoung KIM ; Taejong SONG
Journal of Gynecologic Oncology 2015;26(4):343-349
Borderline ovarian tumors (BOTs) represent about 15% to 20% of all ovarian malignancies and differ from invasive ovarian cancers (IOCs) by many characters. Historically, standard management of BOT is peritoneal washing cytology, hysterectomy, bilateral salpingo-oophorectomy, omentectomy, complete peritoneal resection of macroscopic lesions; in case of mucinous BOTs, appendectomy should be performed. Because BOTs are often diagnosed at earlier stage, in younger age women and have better prognosis, higher survival rate than IOCs, fertility-sparing surgery is one of the option to preserve childbearing capacity. The study of such conservative surgery is being released, and still controversial. After surgery, pregnancy and ovarian induction followed by in vitro fertilization are also significant issues. In surgery, laparoscopic technique can be used by a gynecologic oncology surgeon. So far postoperative chemotherapy, radiotherapy and hormone therapy are not recommended. We will discuss controversial issues of BOTs on this review and present the outline of the management of BOTs.
Biopsy
;
Chemotherapy, Adjuvant
;
Female
;
Humans
;
Infertility, Female/prevention & control
;
Intraoperative Care/methods
;
Laparoscopy/methods
;
Laparotomy/methods
;
Neoplasm Recurrence, Local/therapy
;
Neoplasm Staging
;
Organ Sparing Treatments/methods
;
Ovarian Neoplasms/pathology/*therapy
;
Ovary/*pathology
;
Precancerous Conditions/pathology/therapy
10.Right sided double inferior vena cava with obstructed retrocaval ureter: Managed with single incision multiple port laparoscopic technique using "Santosh Postgraduate Institute tacking ureteric fixation technique".
Santosh KUMAR ; Shivanshu SINGH ; Nitin GARG
Korean Journal of Urology 2015;56(4):330-333
Right double inferior vena cava with obstructed retrocaval ureter is an extremely rare anomaly with only a few reported cases in the literature. To the best of our knowledge, this is the first case report describing ureteric repair by use of a single-incision laparoscopic technique. In addition, this report addresses the underlying surgical challenges of this repair and provides a brief review of the embryology of this anomaly. The "Santosh Postgraduate Institute ureteric tacking fixation technique" provides ease of end-to-end uretero-ureteric anastomosis in a single-incision laparoscopic surgery.
Humans
;
Intraoperative Care/methods
;
Intraoperative Complications/*prevention & control
;
Laparoscopy/methods
;
Magnetic Resonance Imaging
;
Male
;
*Retrocaval Ureter/diagnosis/physiopathology/surgery
;
Treatment Outcome
;
Urography/methods
;
Urologic Surgical Procedures/*methods
;
*Vena Cava, Inferior/abnormalities/surgery
;
Young Adult

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