1.Familial Creutzfeldt–Jakob Disease with a PRNP Mutation at Codon 180 Presented with Visual Hallucinations and Illusions
Dong Woo RYU ; Yun Jeong HONG ; Jeong Wook PARK ; Si Baek LEE ; Seong Hoon KIM ; Yongbang KIM ; Min Jae SEONG ; Byung Seok KIM
Dementia and Neurocognitive Disorders 2019;18(3):105-107
No abstract available.
Codon
;
Hallucinations
;
Illusions
2.Antipsychotic-Induced Oculogyric Crisis and Paroxysmal Perceptual Alteration
In Won CHUNG ; Imyel KIM ; Tak YOUN ; Seong Hoon JEONG ; Hee Yeon JUNG ; Yong Sik KIM
Korean Journal of Schizophrenia Research 2018;21(1):9-20
During antipsychotic drug treatment, clinicians occasionally encounter sudden attacks of oculogyric crisis (OGC) and/or paroxysmal perceptual alteration (PPA) which occur mostly in the afternoon or early evening lasting for minutes to hours and are eventually remitted with rests or short sleep and/or medications such as benzodiazepines, anticholinergics and so forth. Moreover, these attacks are usually accompanied with psychiatric symptoms such as various modalities of hallucinations and illusions, delusions, obsessive thoughts, panic attacks, agitation as well as autonomic symptoms. These accompanying psychiatric symptoms can be perceived as a worsening of psychiatric symptoms if the clinician does not understand the symptoms due to the side effects of antipsychotic drugs, which may result in increasing the dosage of antipsychotics instead of reducing doses or switching to less offending drugs. On the other hand, patients could easily recognize the symptoms as the adverse effects of drugs. This literature review and case-series study is aimed to raise awareness of OGC and PPA by providing clinical cases and author's views with the literature reviews about concepts, recognitions and managements from the works of Japanese authors who first reported the clinical importance of these attacks, particularly PPA.
Antipsychotic Agents
;
Asian Continental Ancestry Group
;
Benzodiazepines
;
Cholinergic Antagonists
;
Delusions
;
Dihydroergotamine
;
Hallucinations
;
Hand
;
Humans
;
Illusions
;
Panic Disorder
;
Schizophrenia
3.The Central Dislocation of Femoral Head in the Transverse and Both Column Acetabular Fractures: Is It Really Medialized?.
Hip & Pelvis 2017;29(3):182-186
PURPOSE: We hypothesized that the central dislocation of the femoral head does generally not occur in transverse acetabular fractures, although it does usually occur in both column fractures. MATERIALS AND METHODS: Fifty-two transverse and both column acetabular fracture cases were evaluated retrospectively. The distances between (a) the sciatic notch on the fracture side and the vertical axis of the pelvis (VA line) and (b) the contralateral intact sciatic notch and the VA line were measured. The a/b ratio corresponded to the superior iliac segment displacement or rotation. The ratio of the distance between the fracture side femoral head and the VA line (c) and the distance between the contralateral intact femoral head and the VA line (d) corresponded to the femoral head displacement. The width of ischium (e) on fractured side and (f) contralateral side were measured. The e/f ratio increment reflected ischiadic fragment mobility. RESULTS: The median value of femoral head displacement (c/d) of the transverse fracture group (n=25) was 1.02 (1.000-1.07). Ischiadic fragment rotation (e/f ratio) of the transverse fracture group was 1.000. The median value of femoral head displacement (c/d) of the both column fractures (n=27) was 0.78 (0.64-0.85). Ischiadic fragment rotation (e/f ratio) of the both-column group was 1.15 (1.06-1.23). The differences between groups according to measurements were statistically significant. CONCLUSION: In contrary to Letournel description, our findings showed no medialization of femoral head in transverse acetabular fractures in general. This might be an illusion resulting from external rotation of the superior iliac segment.
Acetabulum*
;
Dislocations*
;
Head*
;
Hip Dislocation
;
Illusions
;
Ischium
;
Pelvis
;
Retrospective Studies
4.The Central Dislocation of Femoral Head in the Transverse and Both Column Acetabular Fractures: Is It Really Medialized?.
Hip & Pelvis 2017;29(3):182-186
PURPOSE: We hypothesized that the central dislocation of the femoral head does generally not occur in transverse acetabular fractures, although it does usually occur in both column fractures. MATERIALS AND METHODS: Fifty-two transverse and both column acetabular fracture cases were evaluated retrospectively. The distances between (a) the sciatic notch on the fracture side and the vertical axis of the pelvis (VA line) and (b) the contralateral intact sciatic notch and the VA line were measured. The a/b ratio corresponded to the superior iliac segment displacement or rotation. The ratio of the distance between the fracture side femoral head and the VA line (c) and the distance between the contralateral intact femoral head and the VA line (d) corresponded to the femoral head displacement. The width of ischium (e) on fractured side and (f) contralateral side were measured. The e/f ratio increment reflected ischiadic fragment mobility. RESULTS: The median value of femoral head displacement (c/d) of the transverse fracture group (n=25) was 1.02 (1.000-1.07). Ischiadic fragment rotation (e/f ratio) of the transverse fracture group was 1.000. The median value of femoral head displacement (c/d) of the both column fractures (n=27) was 0.78 (0.64-0.85). Ischiadic fragment rotation (e/f ratio) of the both-column group was 1.15 (1.06-1.23). The differences between groups according to measurements were statistically significant. CONCLUSION: In contrary to Letournel description, our findings showed no medialization of femoral head in transverse acetabular fractures in general. This might be an illusion resulting from external rotation of the superior iliac segment.
Acetabulum*
;
Dislocations*
;
Head*
;
Hip Dislocation
;
Illusions
;
Ischium
;
Pelvis
;
Retrospective Studies
5.The Diagnosis and Treatment of the Cervical Vertigo.
Joo Young KIM ; Wee Hwang KIM ; Jang Soo LEE ; Hyun Myung OH ; Dae Woong KIM ; Dong Jin CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 2015;58(3):177-181
BACKGROUND AND OBJECTIVES: Vertigo is an illusion of environmental movement due to various causes, thus it is hard for medical doctors to determine the exact kind of dizziness in the final diagnosis. Recently, cervical vertigo was reported from several vertigo cases. Cervical vertigo is defined as sensation of rotation, resulting from an alteration of the neck proprioceptive afferents of the upper cervical spine. The aim of our study is to document the clinical features and the treatment outcomes in vertigo patients with myofascial pain syndrome (MPS). SUBJECTS AND METHOD: A total of 488 patients, excluding 18 patients who received other diagnosis, were examined to investigate the reasons for dizziness. We evaluated 34 patients, who were diagnosed with cervical vertigo by questionnaire after MPS treatments. Clinical evaluations for cervical vertigo were performed on all subjects, and vestibular function tests were also performed in patients with vertigo symptoms. All patients received a total of 4 treatments including trigger point injection, physical therapy or medication, and then followed up, respectively. The symptom changes of dizziness, patient satisfaction and cervical pain were checked before and treatment 1, 2, 4 times by Visual Analogue Scale (VAS) score. RESULTS: There were significant improvement in the VAS score of dizziness, patient satisfaction and cervical pain after treatment for MPS. CONCLUSION: Treatment for MPS could improve dizziness in cervical vertigo with MPS patients, but further study is needed to clearly confirm the cervical vertigo with MPS for improving patient's quality of life.
Diagnosis*
;
Dizziness
;
Facial Neuralgia
;
Humans
;
Illusions
;
Myofascial Pain Syndromes
;
Neck
;
Neck Pain
;
Patient Satisfaction
;
Quality of Life
;
Surveys and Questionnaires
;
Sensation
;
Spine
;
Trigger Points
;
Vertigo*
;
Vestibular Function Tests
6.Medial Temporal Activation in Mal de Debarquement Syndrome Revealed by Standardized Low-Resolution Brain Electromagnetic Tomography.
Seong Hae JEONG ; Ki Young JUNG ; Jae Moon KIM ; Ji Soo KIM
Journal of Clinical Neurology 2012;8(3):238-240
BACKGROUND: Mal de debarquement (MdD) literally means "sickness of disembarkation", and refers to the illusion of movement perceived as an after-effect of traveling on a boat, train, or airplane. The pathophysiology of MdD is currently unknown. CASE REPORT: A 20-year-old man presented with dizziness and swaying sensation for 3 days after a boat trip. Compared with the follow-up EEG without symptoms, the EEG recorded while having MdD symptoms disclosed a significantly decreased alpha-band current source density at the precentral gyrus of the left frontal lobe and increased beta-2 activity at the parahippocampal gyrus of right mesial temporal region. CONCLUSIONS: Our results provide evidence of deranged cortical activity in MdD. To the best of our knowledge this is the first study to document cortical correlates of MdD using an EEG source-localization method.
Aircraft
;
Brain
;
Dizziness
;
Electroencephalography
;
Follow-Up Studies
;
Frontal Lobe
;
Humans
;
Illusions
;
Magnets
;
Motion Sickness
;
Parahippocampal Gyrus
;
Sensation
;
Ships
;
Temporal Lobe
;
Vertigo
;
Young Adult
7.Development and validation of the Korean Nursing Delirium Scale.
Kyoung Nam KIM ; Cheol Ho KIM ; Kwang Il KIM ; Hyun Jung YOO ; Si Young PARK ; Yeon Hwan PARK
Journal of Korean Academy of Nursing 2012;42(3):414-423
PURPOSE: The aims of this study were to develop and test the validity of the Korean Nursing Delirium Scale (Nu-DESC) for older patients in hospital. METHODS: The Korean Nu-DESC was developed based on the Nu-DESC (Gaudreau, 2005), and revised according to nursing records related to signs and symptoms of older patients with delirium (n=361) and the results of a pilot study (n=42) in one general hospital. To test the validity of the Korean Nu-DESC, 75 older patients whom nurses suspected of delirium from 731 older patients from 12 nursing units were assessed by bedside nurses using the Korean Nu-DESC. A Receiver Operating Characteristic Curve of the Korean Nu-DESC was constructed with an accompanying Area Under the Curve (AUC). RESULTS: Specific examples such as irritable, kidding, sleeping tendency, which were observed by bedside nurses in Korea, were identified in the five features of signs and symptoms of delirium in the instrument. The Korean Nu-DESC was psycho-metrically valid and had a sensitivity and specificity of .81-.76 and .97-.73, respectively. The AUC were .89, .74. CONCLUSION: Results of this study indicate that the Korean Nu-DESC is well-suited for widespread clinical use in busy inpatients settings and shows promise as a research instrument.
Aged
;
Aged, 80 and over
;
Area Under Curve
;
Behavior
;
Communication
;
Confusion
;
Delirium/diagnosis/*nursing
;
Female
;
Hallucinations
;
Hospitals, General
;
Humans
;
Illusions
;
Male
;
Pilot Projects
;
*Program Development
;
Psychomotor Performance
;
Questionnaires
;
ROC Curve
;
Republic of Korea
;
Translating
8.Research on Ocular Fatigability Induced by Multimedia and Instrument Features.
Yoon Soo JANG ; Ungsoo Samuel KIM ; Seung Hee BAEK ; Yong Ran KIM ; Sang Mook GONG
Journal of the Korean Ophthalmological Society 2012;53(5):689-693
PURPOSE: The aim of the present study was to evaluate the different features of such instruments and how they cause ocular fatigability. METHODS: Under the same settings and circumstances, 75 participants were asked to read the novel, "You without me?" in different formats including paper book, E-book (biscuit(R), Interpark Inc., LG INNOTECK LTD, Korea) and LCD reader (iPad(R), Apple Inc., United States). For every 10 minutes of reading, 10 minutes of rest was provided. After finishing the novel, the participants were asked to complete a questionnaire, and the data obtained were statistically analyzed using univariate analysis. RESULTS: Compared to paper book readers (1.93), LCD readers (2.40) complained of insufficient lubrication in the eye (p = 0.038), and experience more letter-floating illusions (1.92) than did paper book readers (1.49) (p = 0.043). Moreover, compared to the other formats including the E-book (20%) and paper book (8%), LCD readers (72%) experienced more significant glare symptoms (n = 23) and could read at a faster rate than the other groups of readers (n = 26). CONCLUSIONS: In the present study, the I-Pad caused ocular fatigability more easily than the other formats examined. No statistical significance of ocular discomfort or fatigability was observed among the different format groups. Further investigation with a greater number of age-controlled participants should be conducted prior to designing a study to determine the best format for reading.
Dry Eye Syndromes
;
Eye
;
Glare
;
Illusions
;
Lubrication
;
Multimedia
;
Surveys and Questionnaires
9.The Unique Theory of Cold Damage Advocated by Medical Practitioners in the Latter Era of the Joseon Dynasty.
Korean Journal of Medical History 2012;21(1):1-24
The issue of cold damage is one of the major topics of orthodox medicine in East Asia. From the historical view of point, most of the medical practitioners have turned The Theory of Cold Damage to account as their grounds for justifying their own argument. However, it is rare to find a book related to The Theory of Cold Damage in Korea's traditional medicine. Therefore, people have perceived the research status of cold damage is unsatisfactory. This problem could be analyzed by dividing it into a medicinal herb problems and theory problem. First, the medicinal herbs needed for the prescription based on The Theory of Cold Damage don't grow in the Korean Peninsula. Accordingly, there were a lot of restrictions on the free use of these prescriptions. Nevertheless, Chinese medicinal herbs were essential to even the use of the prescriptions besides The Theory of Cold Damage. Accordingly, such aspects do little explain the point that there were few medicine books about The Theory of Cold Damage in Korea. On the other hand, it is hard to exclude the guess that the medical practitioners in the period of the Joseon Dynasty might have presented a theoretically different opinion about cold damage. This study did intensive research on this. As a result of examining the medical practitioners in the latter period of the Joseon Dynasty perceived 'the cold damage to positive and negative meridians' as the case where a patient got attacked by cold as a pathogenic factor in a state of the kidney deficiency. They presented the verdict that kidney deficiency was mostly incurred by sexual relations, and the cold damage to positive and negative meridians broke out when a patient got attacked by cold as a pathogenic factor after having sex. it is an original standpoint shedding light on the relationship between cold damage and the kidney deficiency. The medical practitioners in the latter period of the Joseon Dynasty used Donguibogam as a major text for study on cold damage. In other words, Donguibogam includes the well-organized theory of Yeoksu school who regarded the comparison between internal damage and external damage as important. The medical practitioners in the latter period of the Joseon Dynasty managed to form the theory of the cold damage to positive and negative meridians by deepening the relationship between internal damage and external damage, which was highlighted in Donguibogam. The medical practitioners in the Joseon Dynasty didn't show a big interest in the literature itself, or the so-called The Theory of Cold Damage, which was mainly due to not only the realistic problem of the lack of medicinal herbs needed for applying the prescription to cold damage but also the difference between their positions on cold damage. Therefore, the idea of insufficient research on The Theory of Cold Damage is no more than a kind of optical illusion. On the contrary, we may assume that the medical practitioners in the Joseon Dynasty understood and developed The Theory of Cold Damage in their own way.
Asian Continental Ancestry Group
;
Cold Temperature
;
Far East
;
Hand
;
Humans
;
Kidney
;
Korea
;
Light
;
Medicine, Traditional
;
Meridians
;
Optical Illusions
;
Plants, Medicinal
;
Prescriptions
10.A Case of Microscopic Polyangiitis: Glomerulonephritis, Neuropsychiatric Abnormalities, and Urticarial Vasculitis.
Ran Hui CHA ; Ha Jeong LEE ; Soo Hee KIM ; Eun Jung JUNG ; Kyung Chul MOON ; Yon Su KIM
Korean Journal of Nephrology 2010;29(1):98-103
We report a case of microscopic polyangiitis, presenting with rapidly progressive glomerulonephritis, neuropsychiatric abnormalities, and urticarial vasculitis. A 65-year-old woman reported loss of appetite, significant weight loss, and a transient history of veering tendency. She was presented with a mild fever, cough, and sputum. Routine laboratory test revealed anemia, leukocytosis with a left shift, azotemia, and elevated highly sensitive C-reactive protein. The bilateral kidneys were observed to be enlarged (right kidney 16.3 cm, left kidney 18.2 cm) on an abdominal computed tomography. The perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) titer was >1:640 and MPO-ANCA was positive. Her chief complaints consisted of character change, visual illusion, and hearing loss. A skin rash with a bullous change resembling urticaria was further developed. Kidney biopsy demonstrated pauci-immune diffuse crescentic glomerulonephritis. Skin biopsy was compatible with urticarial vasculitis. Having received intravenous cyclophosphamide and oral prednisolone, she showed sustained improvement in renal function, as well as her neuropsychiatric symptoms and skin rash.
Aged
;
Anemia
;
Antibodies, Antineutrophil Cytoplasmic
;
Appetite
;
Azotemia
;
Biopsy
;
C-Reactive Protein
;
Cough
;
Cyclophosphamide
;
Exanthema
;
Female
;
Fever
;
Glomerulonephritis
;
Hearing Loss
;
Humans
;
Illusions
;
Kidney
;
Leukocytosis
;
Microscopic Polyangiitis
;
Neuropsychology
;
Prednisolone
;
Skin
;
Sputum
;
Urticaria
;
Vasculitis
;
Weight Loss

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