Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Pancreatic cancer typically presents as a focal hypoechoic, hypovascular solid mass with irregular margins on ultrasound. Pancreatic tail disease can be difficult to detect on abdominal ultrasonography. A 75-year-old man visited our institution with upper abdominal pain. We successfully visualized a pancreatic tail mass on abdominal transsplenic scan and multiple liver masses via abdominal transverse scan. His diagnosis was confirmed as pancreatic tail cancer with liver metastasis following endoscopic ultrasound-guided fine-needle biopsy. Abdominal transsplenic scan proved valuable for diagnosing pancreatic tail disease because abdominal ultrasound has limited utility for evaluating pancreatic tail masses due to obscuration by bowel gas.

Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy was performed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings and elevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration of malignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identify on imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered as differential diagnosis. Early liver biopsy can help to clarify the diagnosis.

On 11 February, 2020, the World Health Organization announced that COVID-19 was a novel coronavirus disease first detected in Wuhan, Hubei Province, China. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The complete clinical picture is not fully known. Illness ranges from mild to fatal. The common symptoms include fever, cough, and dyspnea usually developing 2-14 days after exposure. However, diarrhea was present in a few patients with COVID-19. We report a case of COVID-19 mimicking acute colitis.

Traditionally, tissue biopsies of kidney lesions are usually performed with CT or percutaneous ultrasound guidance, but biopsies using EUS have rarely been reported. In this report, we describe a case of renal cell carcinoma (RCC) diagnosed using EUS-guided fine-needle aspiration biopsy. A 75-year-old woman taking aspirin due to stable angina continued to exhibit weight loss and anemia and visited the gastroenterology department. No bleeding was observed on upper and lower gastrointestinal endoscopy. A contrast-enhanced mass was observed in the left kidney, accompanied by 8.9×10.8 cm-sized necrosis suggesting RCC on abdominal CT. Chest CT showed masses in both lungs. We planned to administer targeted therapy after pathological confirmation using EUS. Aspirin was continued, and we performed fine-needle biopsy using a 22-gauge needle three times. No adverse events were observed after the procedure. Pathological examination confirmed RCC, clear cell type, and the patient is currently undergoing treatment with sunitinib. EUS-guided fine-needle aspiration biopsy is safe for liver, pancreatic, or other tumors accessible from the upper gastrointestinal tract. This technique shows fewer adverse events. To the best of our knowledge, there have been no other reports on EUS-guided fine-needle aspiration biopsy to identify RCC in Korea.

Traditionally, tissue biopsies of kidney lesions are usually performed with CT or percutaneous ultrasound guidance, but biopsies using EUS have rarely been reported. In this report, we describe a case of renal cell carcinoma (RCC) diagnosed using EUS-guided fine-needle aspiration biopsy. A 75-year-old woman taking aspirin due to stable angina continued to exhibit weight loss and anemia and visited the gastroenterology department. No bleeding was observed on upper and lower gastrointestinal endoscopy. A contrast-enhanced mass was observed in the left kidney, accompanied by 8.9×10.8 cm-sized necrosis suggesting RCC on abdominal CT. Chest CT showed masses in both lungs. We planned to administer targeted therapy after pathological confirmation using EUS. Aspirin was continued, and we performed fine-needle biopsy using a 22-gauge needle three times. No adverse events were observed after the procedure. Pathological examination confirmed RCC, clear cell type, and the patient is currently undergoing treatment with sunitinib. EUS-guided fine-needle aspiration biopsy is safe for liver, pancreatic, or other tumors accessible from the upper gastrointestinal tract. This technique shows fewer adverse events. To the best of our knowledge, there have been no other reports on EUS-guided fine-needle aspiration biopsy to identify RCC in Korea.