1.Treatment Refractory Nausea and Vomiting due to Duodenal Obstruction caused by Annular Pancreas: A Case Report
Young Bae LIM ; Hwal Seok CHO ; Dong Hyun LEE
Korean Journal of Medicine 2025;100(2):91-94
		                        		
		                        			
		                        			 Annular pancreas is a rare congenital abnormality characterized by a ring of pancreatic tissue encircling the descending part of the duodenum. It is considered to originate from incomplete ventral pancreatic bud rotation. A 39-year-old male with refractory nausea and vomiting despite receiving appropriate medical treatment underwent contrast-enhanced computed tomography; it revealed an annular pancreas encircling the descending part of the duodenum. We found that surgical resection of the annular pancreas relieved nausea and vomiting due to duodenal obstruction. 
		                        		
		                        		
		                        		
		                        	
2.Treatment Refractory Nausea and Vomiting due to Duodenal Obstruction caused by Annular Pancreas: A Case Report
Young Bae LIM ; Hwal Seok CHO ; Dong Hyun LEE
Korean Journal of Medicine 2025;100(2):91-94
		                        		
		                        			
		                        			 Annular pancreas is a rare congenital abnormality characterized by a ring of pancreatic tissue encircling the descending part of the duodenum. It is considered to originate from incomplete ventral pancreatic bud rotation. A 39-year-old male with refractory nausea and vomiting despite receiving appropriate medical treatment underwent contrast-enhanced computed tomography; it revealed an annular pancreas encircling the descending part of the duodenum. We found that surgical resection of the annular pancreas relieved nausea and vomiting due to duodenal obstruction. 
		                        		
		                        		
		                        		
		                        	
3.Treatment Refractory Nausea and Vomiting due to Duodenal Obstruction caused by Annular Pancreas: A Case Report
Young Bae LIM ; Hwal Seok CHO ; Dong Hyun LEE
Korean Journal of Medicine 2025;100(2):91-94
		                        		
		                        			
		                        			 Annular pancreas is a rare congenital abnormality characterized by a ring of pancreatic tissue encircling the descending part of the duodenum. It is considered to originate from incomplete ventral pancreatic bud rotation. A 39-year-old male with refractory nausea and vomiting despite receiving appropriate medical treatment underwent contrast-enhanced computed tomography; it revealed an annular pancreas encircling the descending part of the duodenum. We found that surgical resection of the annular pancreas relieved nausea and vomiting due to duodenal obstruction. 
		                        		
		                        		
		                        		
		                        	
4.Treatment Refractory Nausea and Vomiting due to Duodenal Obstruction caused by Annular Pancreas: A Case Report
Young Bae LIM ; Hwal Seok CHO ; Dong Hyun LEE
Korean Journal of Medicine 2025;100(2):91-94
		                        		
		                        			
		                        			 Annular pancreas is a rare congenital abnormality characterized by a ring of pancreatic tissue encircling the descending part of the duodenum. It is considered to originate from incomplete ventral pancreatic bud rotation. A 39-year-old male with refractory nausea and vomiting despite receiving appropriate medical treatment underwent contrast-enhanced computed tomography; it revealed an annular pancreas encircling the descending part of the duodenum. We found that surgical resection of the annular pancreas relieved nausea and vomiting due to duodenal obstruction. 
		                        		
		                        		
		                        		
		                        	
5.Short-term outcomes of intravesical gemcitabine for non-muscle-invasive bladder cancer after recent approval for use in Korea
Gang Kyu KIM ; Young Heun JO ; Jongsoo LEE ; Hyun Ho HAN ; Won Sik HAM ; Won Sik JANG ; Ji Eun HEO
Investigative and Clinical Urology 2024;65(5):435-441
		                        		
		                        			 Purpose:
		                        			In high-risk non-muscle-invasive bladder cancer (NMIBC), intravesical Bacillus Calmette-Guérin (BCG) is the standard adjuvant therapy post-transurethral resection of bladder tumor (TURBT). Intravesical gemcitabine, used as an alternative or second-line therapy amid BCG shortages, lacks outcome studies in the Korean population. 
		                        		
		                        			Materials and Methods:
		                        			Patients who received weekly intravesical gemcitabine for 6 weeks after TURBT from 2019 to 2022 were retrospectively investigated. Based on the American Urological Association risk classification, patients with high- or very high-risk NMIBC who refused cystectomy were included. Maintenance treatment was performed depending on their risk. Recurrence was defined as histologic confirmation on subsequent cystoscopic biopsies or TURBT. Disease free survival (DFS) was evaluated by the Kaplan–Meier method. 
		                        		
		                        			Results:
		                        			The study included 60 patients, comprising 45 high-risk (group 1) patients with a median age of 76 years and 15 very high-risk (group 2) patients with a median age of 68 years. Among them, 28 patients had previously received intravesical BCG.Over a median follow-up of 22 months, recurrence occurred in 31 patients in group 1 and 11 in group 2. The DFS rates of the highrisk group and the very high-risk group were 57.8% versus 40% at 1 year, 20.7% versus 21.3% at 2 years and 20.7% versus 21.3% at 3 years, respectively (p=0.831). Tis stage (p=0.042) and prostatic urethra invasion (p=0.028) were significant predictors of DFS.Cancer-specific mortality rates were 2.2% in group 1 and 6.7% in group 2 (p=0.441). 
		                        		
		                        			Conclusions
		                        			Similar DFS outcome between high-risk and very high-risk patients were observed based on short-term results in Korea. This finding is crucial for clinical practice; however, studies analyzing more patients and long-term outcomes are needed. 
		                        		
		                        		
		                        		
		                        	
6.Comparison of Synergistic Sedation with Midazolam and Propofol Versus Midazolam and Pethidine in Colonoscopies: A Prospective, Randomized Controlled Study
Jae Woong LIM ; Min Jae KIM ; Gang Han LEE ; Dae Sol KIM ; Sang Hyuk JUNG ; Yu Yeon KIM ; Jin Won KIM ; Yohan LEE ; Hyun Soo KIM ; Seon Young PARK ; Dong Hyun KIM
Chonnam Medical Journal 2024;60(3):192-197
		                        		
		                        			
		                        			 Colonoscopy is a key procedure for the early detection of colorectal cancer. Despite its importance, the discomfort associated with colonoscopy often requires sedation, and the ideal sedation regimen remains to be determined. In this prospective randomized controlled trial, patients scheduled for colonoscopy were randomly assigned to two different sedation protocols. Group A received a combination of midazolam and propofol, while group B was given midazolam and pethidine. The study analyzed data from 51 patients, with 23 in group A and 28 in group B. The incidence of adverse events was similar across both groups. Additionally, no significant differences were observed in cecal intubation times or total procedure durations. Notably, group A had a lower frequency of required postural changes (1.0±0.7 vs. 1.5±0.7, p=0.02) and a reduced rate of manual compression (52.2% vs. 82.1%, p=0.02). There were no significant differences between the groups regarding subjective pain or overall satisfaction. Both sedation regimens were found to be safe and effective. The midazolam and propofol combination was associated with a smoother procedure, evidenced by fewer postural adjustments and less manual compression needed during colonoscopy. 
		                        		
		                        		
		                        		
		                        	
8.Successful Simultaneous Treatment of Benign Stricture and Colonic Neoplasm Arising from Colonic Interposition after Esophagectomy: A Case Report
Seung Hee KIM ; Jin Won KIM ; Seon-Young PARK ; Hyun-Soo KIM ; Chae June LIM ; Gang Han LEE ; Jae Woong LIM ; Young Eun SEO ; Shin Young PARK ; Yo Han LEE ; Yong-Wook JUNG ; Woo Rim KANG ; Hye-Su YOU ; Dong Hyun KIM
The Korean Journal of Gastroenterology 2023;82(3):140-144
		                        		
		                        			
		                        			 Colonic interposition is the main procedure used in esophageal reconstruction. We report a rare case of simultaneous treatment of an anastomotic site stricture and a neoplasm in the interpositioned colon. A 69-year-old female visited our outpatient clinic with symptoms of progressive dysphagia for 1 year. At the age of 30 years, the patient underwent esophagectomy with retrosternal colonic interposition because of severe esophageal burns after chemical ingestion. Upper gastrointestinal endoscopy revealed stricture at the anastomosis site and a 10-mm flat elevated high-grade dysplasia in the interpositioned colon. First, through-the-scope balloon dilatation was performed for strictures. However, stenosis was observed during the second upper gastrointestinal endoscopy session.Therefore, a second session of through-the-scope balloon dilatation was performed, and simultaneously, endoscopic submucosal dissection was also successfully performed. After 2 months of follow-up, stenosis persisted; consequently, balloon dilatation was performed. No recurrence of neoplasm was confirmed endoscopically. Through-the-scope balloon dilatation of the stricture site and simultaneous endoscopic submucosal dissection of the neoplasm in the interpositioned colon were successfully performed. 
		                        		
		                        		
		                        		
		                        	
9.Effect of shared decision-making education on physicians’ perceptions and practices of end-of-life care in Korea
Byung Chul YU ; Miyeun HAN ; Gang-Jee KO ; Jae Won YANG ; Soon Hyo KWON ; Sungjin CHUNG ; Yu Ah HONG ; Young Youl HYUN ; Jang-Hee CHO ; Kyung Don YOO ; Eunjin BAE ; Woo Yeong PARK ; In O SUN ; Dongryul KIM ; Hyunsuk KIM ; Won Min HWANG ; Sang Heon SONG ; Sung Joon SHIN
Kidney Research and Clinical Practice 2022;41(2):242-252
		                        		
		                        			
		                        			 Evidence of the ethical appropriateness and clinical benefits of shared decision-making (SDM) are accumulating. This study aimed to not only identify physicians’ perspectives on SDM, and practices related to end-of-life care in particular, but also to gauge the effect of SDM education on physicians in Korea. Methods: A 14-item questionnaire survey using a modified Delphi process was delivered to nephrologists and internal medicine trainees at 17 university hospitals. Results: A total of 309 physicians completed the survey. Although respondents reported that 69.9% of their practical decisions were made using SDM, 59.9% reported that it is not being applied appropriately. Only 12.3% of respondents had received education on SDM as part of their training. The main obstacles to appropriate SDM were identified as lack of time (46.0%), educational materials and tools (29.4%), and education on SDM (24.3%). Although only a few respondents had received training on SDM, the proportion of those who thought they were using SDM appropriately in actual practice was high; the proportion of those who chose lack of time and education as factors that hindered the proper application of SDM was low. Conclusion: The majority of respondents believed that SDM was not being implemented properly in Korea, despite its use in actual practice. To improve the effectiveness of SDM in the Korean medical system, appropriate training programs and supplemental policies that guarantee sufficient application time are required. 
		                        		
		                        		
		                        		
		                        	
10.A Study of Otologic Symptoms and Prognosis in Patients With Ramsay Hunt Syndrome and Bell’s Palsy
Soo Young CHOI ; Tong In OH ; Eun Hye LEE ; Jae Min LEE ; Gang Won CHOI ; Hyun Ji LEE ; Sang Hoon KIM ; Seung Geun YEO
Korean Journal of Otolaryngology - Head and Neck Surgery 2022;65(5):260-267
		                        		
		                        			 Background and Objectives:
		                        			Although several studies have compared the characteristics of Ramsay Hunt syndrome (RHS) with Bell’s palsy (BP), the differences in comorbid symptoms and prognosis according to symptoms have not been determined. This study therefore evaluated the differences in otologic symptoms and prognosis between patients with these two conditions.Subjects and Method The medical records of 118 patients with RHS and 215 patients with BP were retrospectively reviewed. Factors compared in these two groups included otologic symptoms, general health condition, electroneurography (ENoG) and House-Brackmann grades. 
		                        		
		                        			Results:
		                        			Age, sex, body mass index, lipid profiles, ENoG, rate of diabetes, and side of palsy did not differ significantly between patients with RHS and BP (p>0.05). The rates of hearing disturbance, tinnitus, vertigo, and postauricular pain were significantly higher in RHS (p<0.05 each). Hearing disturbance was more frequent in patients with severe Bell’s facial palsy than with moderate Bell’s facial palsy (p<0.05). The prognosis of patients with BP and RHS who had otologic symptoms did not differ from those who had not (p>0.05). Additionally, in patients with facial paralysis, diabetes was associated with hearing disturbance and vertigo symptoms and dyslipidemia was associated with postauricular pain (p<0.05 each). 
		                        		
		                        			Conclusion
		                        			Otologic symptoms were more common in RHS than in BP. However, the prognosis of RHS and BP were not related to otologic symptoms. In patients with facial palsy hearing disturbance and vertigo were associated with diabetes and hypertension. Also, dyslipidemia was associated with post auricular pain. 
		                        		
		                        		
		                        		
		                        	
            
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