1.Depth-Dependent Performance of Single-Shade Composite Resin: Assessing Color Adjustment Potential and Translucency
Hyewon SHIN ; Haeni KIM ; Juhyun LEE
Journal of Korean Academy of Pediatric Dentistry 2025;52(1):9-20
The blending effect refers to a phenomenon where the color difference between the restorative material and surrounding tooth structure appears smaller when they are adjacent to each other. The effect can be affected by the translucency of restorative material. This study evaluated the influence of cavity depth on the color adjustment potential (CAP) and translucency of a single-shade composite resin compared to multi-shade composite resins. A single-shade composite (Omnichroma) and two multi-shade composites (FiltekTM Z350 XT and Estelite® Sigma Quick) were tested in 1.5 mm and 3.0 mm cavity depths/thicknesses. CAP was assessed using the ΔEab* color difference between single and dual specimens. Translucency was measured using the translucency parameter (TP). The single-shade composite demonstrated significantly higher CAP and TP values compared to multi-shade composites across all depths/thicknesses (p < 0.0167). CAP decreased with increasing cavity depth for all composites. In 1.5 mm cavities, the single-shade composite achieved a clinically imperceptible color match (ΔEab* < 3.7). The higher translucency of the single-shade composite likely contributes to its enhanced blending effect and CAP. These results suggest that single-shade composites offer superior shade-matching ability due to their structural color phenomenon and high translucency. However, the decrease in CAP with increasing cavity depth indicates potential limitations in deeper restorations. Clinicians should consider appropriate techniques or additional products for optimal aesthetic outcomes in deeper cavities when using single-shade composites.
2.Clinical Significance of Various Pathogens Identified in Patients Experiencing Acute Exacerbations of COPD: A Multi-center Study in South Korea
Hyun Woo JI ; Soojoung YU ; Yun Su SIM ; Hyewon SEO ; Jeong-Woong PARK ; Kyung Hoon MIN ; Deog Kyeom KIM ; Hyun Woo LEE ; Chin Kook RHEE ; Yong Bum PARK ; Kyeong-Cheol SHIN ; Kwang Ha YOO ; Ji Ye JUNG
Tuberculosis and Respiratory Diseases 2025;88(2):292-302
Background:
Respiratory infections play a major role in acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This study assessed the prevalence of bacterial and viral pathogens and their clinical impact on patients with AECOPD.
Methods:
This retrospective study included 1,186 patients diagnosed with AECOPD at 28 hospitals in South Korea between 2015 and 2018. We evaluated the identification rates of pathogens, basic patient characteristics, clinical features, and the factors associated with infections by potentially drug-resistant (PDR) pathogens using various microbiological tests.
Results:
Bacteria, viruses, and both were detected in 262 (22.1%), 265 (22.5%), and 129 (10.9%) of patients, respectively. The most common pathogens included Pseudomonas aeruginosa (17.8%), Mycoplasma pneumoniae (11.2%), Streptococcus pneumoniae (9.0%), influenza A virus (19.0%), rhinovirus (15.8%), and respiratory syncytial virus (6.4%). Notably, a history of pulmonary tuberculosis (odds ratio [OR], 1.66; p=0.046), bronchiectasis (OR, 1.99; p=0.032), and the use of a triple inhaler regimen within the past 6 months (OR, 2.04; p=0.005) were identified as significant factors associated with infection by PDR pathogens. Moreover, patients infected with PDR pathogens exhibited extended hospital stays (15.9 days vs. 12.4 days, p=0.018) and higher intensive care unit admission rates (15.9% vs. 9.5%, p=0.030).
Conclusion
This study demonstrates that a variety of pathogens are involved in episodes of AECOPD. Nevertheless, additional research is required to confirm their role in the onset and progression of AECOPD.
3.Childbearing intentions and influencing factors among single young adults in South Korea: a cross-sectional study
Hyewon SHIN ; Anna LEE ; Sunyeob CHOI ; Minjeong JO
Child Health Nursing Research 2025;31(1):15-27
Purpose:
To identify the childbearing intentions of young adults in South Korea and examine the factors influencing them using a social-ecological model (SEM).
Methods:
A descriptive cross-sectional study design was used. Unmarried employed men and women (n=181) aged 25–40 years completed an online survey. The data included socio-demographic characteristics and responses at four levels: (1) intrapersonal (perception of parenthood and fertility knowledge), (2) interpersonal (quality of family relationships), (3) institutional (work-family culture), and (4) community and public policy (adequacy of government policies and social support systems). Data were analyzed using descriptive statistics, correlations, and multiple logistic regression.
Results:
Approximately 77% of the participants planned to have children, and more than 60% wanted to have two or more children. Among the four levels of SEM, only intrapersonal factors, including intention to marry, fertility knowledge, and attitudes toward parenthood, were statistically significant in influencing childbearing intentions. The model explaining the intention to have a child demonstrated an explanatory power of 59.6%, incorporating factors such as marital intention, perceptions of parenthood, and fertility knowledge.
Conclusion
A noticeable gap exists between childbearing intentions and childbirth in South Korea. These findings provide insights into the nursing educational content needed for delivering family planning education to young adults. Targeted interventions such as counseling services and community education should be integrated into nursing practice. Moreover, nursing curricula should discuss factors influencing childbearing intentions to equip future nurses better to support young adults' family planning decisions.
4.Clinical Significance of Various Pathogens Identified in Patients Experiencing Acute Exacerbations of COPD: A Multi-center Study in South Korea
Hyun Woo JI ; Soojoung YU ; Yun Su SIM ; Hyewon SEO ; Jeong-Woong PARK ; Kyung Hoon MIN ; Deog Kyeom KIM ; Hyun Woo LEE ; Chin Kook RHEE ; Yong Bum PARK ; Kyeong-Cheol SHIN ; Kwang Ha YOO ; Ji Ye JUNG
Tuberculosis and Respiratory Diseases 2025;88(2):292-302
Background:
Respiratory infections play a major role in acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This study assessed the prevalence of bacterial and viral pathogens and their clinical impact on patients with AECOPD.
Methods:
This retrospective study included 1,186 patients diagnosed with AECOPD at 28 hospitals in South Korea between 2015 and 2018. We evaluated the identification rates of pathogens, basic patient characteristics, clinical features, and the factors associated with infections by potentially drug-resistant (PDR) pathogens using various microbiological tests.
Results:
Bacteria, viruses, and both were detected in 262 (22.1%), 265 (22.5%), and 129 (10.9%) of patients, respectively. The most common pathogens included Pseudomonas aeruginosa (17.8%), Mycoplasma pneumoniae (11.2%), Streptococcus pneumoniae (9.0%), influenza A virus (19.0%), rhinovirus (15.8%), and respiratory syncytial virus (6.4%). Notably, a history of pulmonary tuberculosis (odds ratio [OR], 1.66; p=0.046), bronchiectasis (OR, 1.99; p=0.032), and the use of a triple inhaler regimen within the past 6 months (OR, 2.04; p=0.005) were identified as significant factors associated with infection by PDR pathogens. Moreover, patients infected with PDR pathogens exhibited extended hospital stays (15.9 days vs. 12.4 days, p=0.018) and higher intensive care unit admission rates (15.9% vs. 9.5%, p=0.030).
Conclusion
This study demonstrates that a variety of pathogens are involved in episodes of AECOPD. Nevertheless, additional research is required to confirm their role in the onset and progression of AECOPD.
5.Clinical Significance of Various Pathogens Identified in Patients Experiencing Acute Exacerbations of COPD: A Multi-center Study in South Korea
Hyun Woo JI ; Soojoung YU ; Yun Su SIM ; Hyewon SEO ; Jeong-Woong PARK ; Kyung Hoon MIN ; Deog Kyeom KIM ; Hyun Woo LEE ; Chin Kook RHEE ; Yong Bum PARK ; Kyeong-Cheol SHIN ; Kwang Ha YOO ; Ji Ye JUNG
Tuberculosis and Respiratory Diseases 2025;88(2):292-302
Background:
Respiratory infections play a major role in acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This study assessed the prevalence of bacterial and viral pathogens and their clinical impact on patients with AECOPD.
Methods:
This retrospective study included 1,186 patients diagnosed with AECOPD at 28 hospitals in South Korea between 2015 and 2018. We evaluated the identification rates of pathogens, basic patient characteristics, clinical features, and the factors associated with infections by potentially drug-resistant (PDR) pathogens using various microbiological tests.
Results:
Bacteria, viruses, and both were detected in 262 (22.1%), 265 (22.5%), and 129 (10.9%) of patients, respectively. The most common pathogens included Pseudomonas aeruginosa (17.8%), Mycoplasma pneumoniae (11.2%), Streptococcus pneumoniae (9.0%), influenza A virus (19.0%), rhinovirus (15.8%), and respiratory syncytial virus (6.4%). Notably, a history of pulmonary tuberculosis (odds ratio [OR], 1.66; p=0.046), bronchiectasis (OR, 1.99; p=0.032), and the use of a triple inhaler regimen within the past 6 months (OR, 2.04; p=0.005) were identified as significant factors associated with infection by PDR pathogens. Moreover, patients infected with PDR pathogens exhibited extended hospital stays (15.9 days vs. 12.4 days, p=0.018) and higher intensive care unit admission rates (15.9% vs. 9.5%, p=0.030).
Conclusion
This study demonstrates that a variety of pathogens are involved in episodes of AECOPD. Nevertheless, additional research is required to confirm their role in the onset and progression of AECOPD.
6.Tuberculous and Malignant Pleural Effusions With Adenosine Deaminase Levels of 40–70 IU/L: Trends in New Cases Over Time and Differentiation Between Groups
Jaehee LEE ; Jongmin PARK ; Jae Kwang LIM ; Ji Eun PARK ; Yong Hoon LEE ; Sun Ha CHOI ; Hyewon SEO ; Seung Soo YOO ; Shin Yup LEE ; Seung-Ick CHA ; Jae Yong PARK ; Chang Ho KIM
Journal of Korean Medical Science 2025;40(13):e35-
Background:
The diagnosis of tuberculous pleural effusion (TPE) often relies on pleural fluid adenosine deaminase (ADA) levels. The diagnostic utility of ADA, however, is influenced by the prevalence of tuberculosis (TB) in local populations. Malignant pleural effusion (MPE) cases can exhibit moderately elevated ADA levels comparable to those seen in TPE. As population aging potentially impacts ADA levels, global TB incidence is decreasing whereas the burden of malignancy is on the rise. Consequently, epidemiological shifts and temporal changes in ADA distribution complicate the differential diagnosis between TPE and MPE when ADA levels are within the 40–70 IU/L range. Nonetheless, data specific to this subset are scarce.
Methods:
This retrospective study included consecutive patients aged > 18 years with confirmed TPE and MPE, spanning from 2012 to 2023. ADA levels in pleural fluid were categorized into three groups: < 40 IU/L, 40–70 IU/L, and > 70 IU/L. The study examined annual trends in the frequency of new cases and ADA level distributions over time and identified discriminating factors between TPE and MPE in cases with ADA levels of 40–70 IU/L.
Results:
In total, 297 TPE and 369 MPE cases were included in this study. Over the study period, the frequency of TPE progressively declined, while that of MPE increased. In the most recent four-year period, new TPE and MPE cases with ADA levels of 40–70 IU/L occurred at comparable numbers. Multivariable analysis identified pleural fluid carcinoembryonic antigen (CEA) levels and the number of focal pleural nodules as independent predictors for MPE. Specifically, the presence of either CEA levels > 15.7 ng/mL or more than eight pleural nodules yielded the highest diagnostic accuracy with a sensitivity of 88%, specificity of 100%, and an area under the curve of 0.95.
Conclusion
The differential diagnosis between TPE and MPE with pleural ADA levels of 40–70 IU/L has become increasingly critical due to evolving epidemiological patterns and ADA distribution changes over time. Pleural fluid CEA levels and the characteristics of pleural nodules may offer valuable guidance in distinguishing between TPE and MPE within this diagnostic gray zone.
7.Tuberculous and Malignant Pleural Effusions With Adenosine Deaminase Levels of 40–70 IU/L: Trends in New Cases Over Time and Differentiation Between Groups
Jaehee LEE ; Jongmin PARK ; Jae Kwang LIM ; Ji Eun PARK ; Yong Hoon LEE ; Sun Ha CHOI ; Hyewon SEO ; Seung Soo YOO ; Shin Yup LEE ; Seung-Ick CHA ; Jae Yong PARK ; Chang Ho KIM
Journal of Korean Medical Science 2025;40(13):e35-
Background:
The diagnosis of tuberculous pleural effusion (TPE) often relies on pleural fluid adenosine deaminase (ADA) levels. The diagnostic utility of ADA, however, is influenced by the prevalence of tuberculosis (TB) in local populations. Malignant pleural effusion (MPE) cases can exhibit moderately elevated ADA levels comparable to those seen in TPE. As population aging potentially impacts ADA levels, global TB incidence is decreasing whereas the burden of malignancy is on the rise. Consequently, epidemiological shifts and temporal changes in ADA distribution complicate the differential diagnosis between TPE and MPE when ADA levels are within the 40–70 IU/L range. Nonetheless, data specific to this subset are scarce.
Methods:
This retrospective study included consecutive patients aged > 18 years with confirmed TPE and MPE, spanning from 2012 to 2023. ADA levels in pleural fluid were categorized into three groups: < 40 IU/L, 40–70 IU/L, and > 70 IU/L. The study examined annual trends in the frequency of new cases and ADA level distributions over time and identified discriminating factors between TPE and MPE in cases with ADA levels of 40–70 IU/L.
Results:
In total, 297 TPE and 369 MPE cases were included in this study. Over the study period, the frequency of TPE progressively declined, while that of MPE increased. In the most recent four-year period, new TPE and MPE cases with ADA levels of 40–70 IU/L occurred at comparable numbers. Multivariable analysis identified pleural fluid carcinoembryonic antigen (CEA) levels and the number of focal pleural nodules as independent predictors for MPE. Specifically, the presence of either CEA levels > 15.7 ng/mL or more than eight pleural nodules yielded the highest diagnostic accuracy with a sensitivity of 88%, specificity of 100%, and an area under the curve of 0.95.
Conclusion
The differential diagnosis between TPE and MPE with pleural ADA levels of 40–70 IU/L has become increasingly critical due to evolving epidemiological patterns and ADA distribution changes over time. Pleural fluid CEA levels and the characteristics of pleural nodules may offer valuable guidance in distinguishing between TPE and MPE within this diagnostic gray zone.
8.Childbearing intentions and influencing factors among single young adults in South Korea: a cross-sectional study
Hyewon SHIN ; Anna LEE ; Sunyeob CHOI ; Minjeong JO
Child Health Nursing Research 2025;31(1):15-27
Purpose:
To identify the childbearing intentions of young adults in South Korea and examine the factors influencing them using a social-ecological model (SEM).
Methods:
A descriptive cross-sectional study design was used. Unmarried employed men and women (n=181) aged 25–40 years completed an online survey. The data included socio-demographic characteristics and responses at four levels: (1) intrapersonal (perception of parenthood and fertility knowledge), (2) interpersonal (quality of family relationships), (3) institutional (work-family culture), and (4) community and public policy (adequacy of government policies and social support systems). Data were analyzed using descriptive statistics, correlations, and multiple logistic regression.
Results:
Approximately 77% of the participants planned to have children, and more than 60% wanted to have two or more children. Among the four levels of SEM, only intrapersonal factors, including intention to marry, fertility knowledge, and attitudes toward parenthood, were statistically significant in influencing childbearing intentions. The model explaining the intention to have a child demonstrated an explanatory power of 59.6%, incorporating factors such as marital intention, perceptions of parenthood, and fertility knowledge.
Conclusion
A noticeable gap exists between childbearing intentions and childbirth in South Korea. These findings provide insights into the nursing educational content needed for delivering family planning education to young adults. Targeted interventions such as counseling services and community education should be integrated into nursing practice. Moreover, nursing curricula should discuss factors influencing childbearing intentions to equip future nurses better to support young adults' family planning decisions.
9.Tuberculous and Malignant Pleural Effusions With Adenosine Deaminase Levels of 40–70 IU/L: Trends in New Cases Over Time and Differentiation Between Groups
Jaehee LEE ; Jongmin PARK ; Jae Kwang LIM ; Ji Eun PARK ; Yong Hoon LEE ; Sun Ha CHOI ; Hyewon SEO ; Seung Soo YOO ; Shin Yup LEE ; Seung-Ick CHA ; Jae Yong PARK ; Chang Ho KIM
Journal of Korean Medical Science 2025;40(13):e35-
Background:
The diagnosis of tuberculous pleural effusion (TPE) often relies on pleural fluid adenosine deaminase (ADA) levels. The diagnostic utility of ADA, however, is influenced by the prevalence of tuberculosis (TB) in local populations. Malignant pleural effusion (MPE) cases can exhibit moderately elevated ADA levels comparable to those seen in TPE. As population aging potentially impacts ADA levels, global TB incidence is decreasing whereas the burden of malignancy is on the rise. Consequently, epidemiological shifts and temporal changes in ADA distribution complicate the differential diagnosis between TPE and MPE when ADA levels are within the 40–70 IU/L range. Nonetheless, data specific to this subset are scarce.
Methods:
This retrospective study included consecutive patients aged > 18 years with confirmed TPE and MPE, spanning from 2012 to 2023. ADA levels in pleural fluid were categorized into three groups: < 40 IU/L, 40–70 IU/L, and > 70 IU/L. The study examined annual trends in the frequency of new cases and ADA level distributions over time and identified discriminating factors between TPE and MPE in cases with ADA levels of 40–70 IU/L.
Results:
In total, 297 TPE and 369 MPE cases were included in this study. Over the study period, the frequency of TPE progressively declined, while that of MPE increased. In the most recent four-year period, new TPE and MPE cases with ADA levels of 40–70 IU/L occurred at comparable numbers. Multivariable analysis identified pleural fluid carcinoembryonic antigen (CEA) levels and the number of focal pleural nodules as independent predictors for MPE. Specifically, the presence of either CEA levels > 15.7 ng/mL or more than eight pleural nodules yielded the highest diagnostic accuracy with a sensitivity of 88%, specificity of 100%, and an area under the curve of 0.95.
Conclusion
The differential diagnosis between TPE and MPE with pleural ADA levels of 40–70 IU/L has become increasingly critical due to evolving epidemiological patterns and ADA distribution changes over time. Pleural fluid CEA levels and the characteristics of pleural nodules may offer valuable guidance in distinguishing between TPE and MPE within this diagnostic gray zone.
10.Depth-Dependent Performance of Single-Shade Composite Resin: Assessing Color Adjustment Potential and Translucency
Hyewon SHIN ; Haeni KIM ; Juhyun LEE
Journal of Korean Academy of Pediatric Dentistry 2025;52(1):9-20
The blending effect refers to a phenomenon where the color difference between the restorative material and surrounding tooth structure appears smaller when they are adjacent to each other. The effect can be affected by the translucency of restorative material. This study evaluated the influence of cavity depth on the color adjustment potential (CAP) and translucency of a single-shade composite resin compared to multi-shade composite resins. A single-shade composite (Omnichroma) and two multi-shade composites (FiltekTM Z350 XT and Estelite® Sigma Quick) were tested in 1.5 mm and 3.0 mm cavity depths/thicknesses. CAP was assessed using the ΔEab* color difference between single and dual specimens. Translucency was measured using the translucency parameter (TP). The single-shade composite demonstrated significantly higher CAP and TP values compared to multi-shade composites across all depths/thicknesses (p < 0.0167). CAP decreased with increasing cavity depth for all composites. In 1.5 mm cavities, the single-shade composite achieved a clinically imperceptible color match (ΔEab* < 3.7). The higher translucency of the single-shade composite likely contributes to its enhanced blending effect and CAP. These results suggest that single-shade composites offer superior shade-matching ability due to their structural color phenomenon and high translucency. However, the decrease in CAP with increasing cavity depth indicates potential limitations in deeper restorations. Clinicians should consider appropriate techniques or additional products for optimal aesthetic outcomes in deeper cavities when using single-shade composites.

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