Valeriane (Valeriana officinalis L.; Valerianaceae) is a perennial herbaceous plant common in Europe, North America and North Asia. The medicinal properties of the valeriane have been recognized as far back as the early Greeks and Romans, and in medieval time it was used to treat a variety of ailments. Valerian has a direct sedative effect and interacts with neurotransmitters such as GABA. Now a day it is considered as a safe herbal choice for mild insomnia and has good tolerability. One of the potential advantages of valeriane over benzodiazepines (BZDs) is the lack of daylight sleepiness when used at recommended dosages (300 to 600mg in capsule form, taken 30 minutes to 2 hours before bedtime). It also may be helpful in weaning patients with insomnia due to BZDs.
Valeriane ; Insomnia

Studies of 11 biosimilarities. Result: in vitro bioactive was from 71-226% compared to Eprex. 9/11 biosilmilars had different isome from standard. Among 12 samples from 5 producers, the effectiveness was from 67.6% to 119.4% differently from European stardard. In three samples, toxic level was 15 higher than maximum accepted starndard. Isomeric samples also varied among producers. The study showed Epoetin produced outside of The United States and Europe had very different elements not in conformity with full process. The content on label was often lower or exceeded the limit.
Pharmaceutical Preparations, Medicine

Updates on the use of vardenafil (Levitra) in the treatment of erection disorders including: specific inhibition with PDE5, treatment efficacy, pharmacokinetics, tolerance level, interaction, contraindication, cautions especially for people with cardiovascular diseases or penis surgery deformation, dosage and use. Except for above contraindication and cautions, vardenafil can be considered as first choice for men with erection disorders in accordance with PDE5 inhibition treatment
Penile Erection ; Imidazoles ; Piperazines ; Therapeutics

Some protein, at acute phase were usually used to diagnose and to monitor the status of inflammation in infection diseases. In healthy person, CRP exists only in the form of patch, but CRP is as an sensitive indicator of a reaction of systemic inflammation, in turn, inflammation had a key role in physiopathology of arteriosclerosis. Person with high content of CRP will have a 4.5 fold risk of heart attack in comparing with healthy one. Moreover it has diverse manifestations in other severe diseases such as blood sugar disorders, dental gingival diseases, smoking, overweight and obese
Inflammation ; C-Reactive Protein ; diagnosis ;

Red wine contains much active substances of super antioxydant with great value of preventing and treating diseases. In vitro and in vivo researches on inimal, epidemiological investigations conducted on human hah demonstrated a bright future on the prevention and treatment of atherosclerosis, cancer, viral diseases and mental declining, Alzheimer disease… Moderate use daily of red wine offers considerable advantage for health and prolongs the longevity. However, because of the containing of alcohol, it must weigh the pros and cons in using red wine.
Wine ; preventive medicine ; Primary prevention ; Public health

Squalen, a compound detected in olive oil, had an activity against coloileal cancer due to azoxymethan in rats and lung cancer due to nitrosamin in mice. Squalen is a mediate substance in biosynthesis of mevaloat/cholesterol. Squalen is synthetised by catalysis squalen syntherase but it inhibits this enzyme which lead the reverse inhibition of HMG-CoA reductase to reduce the first stage of cholesterol synthesis. The more important outcome was that squalen inhibits protein transferees, which is an enzyme that is necessary for farnesrylization of rasprotein causing cancer
Squalene ; neoplasms

Artemisinin, a sesquiterpen lacton, is an active ingredient of the sweet wormwood plant. It is used mostly for malaria. It can kill the cancer cell by following mechanism: endoperoxyd junction of artemisinin degrades haem (containing Fe), after reaction, new generated free radicals akylate and oxygenate protein and lipid, deteriorate macromolecular and kill the parasite without significant adverse effects. Administration of artemisinin derivatives with acceptable dosage and combination with a iron salt can produce potent effect on cancer, especially on breast cancer.
Breast Neoplasms ; therapeutics ; artemisinine ; breast ; neoplasms

The disadvantage factors related with arteriosclerosis including less moving, obesity, alcohol and smoking. Recently, there has been a "nonlipid" factor of cardiovascular disease - chlamydia pneumonia infection. In order to prevent from late complication of arteriosclerosis and cardiovascular disease due to the chlamydia pneumonia, it should use macrolid, tetracycline and quinolon in case of chlamydia pneumonia infection. The Beta-latamine has no effect on chlamydia pneumonia infection
Arteriosclerosis ; Anti-Bacterial Agents

The side effects of cerivastatin on the skeletal muscle include muscle pain, muscle weakness accompanying with the increased creatinin - kinase rarely malignant hypermyoglobin uric leading the secondary renal failure. The Bayer pharmaceutical Company withdrawed all dosage form of cerivastatin in England and America in the 8th and 9th August 2001.
Pyridines ; Withholding Treatment

Saturated fatty acids increase LDL - cholesterol (bad cholesterol) and total cholesterol. The olive, corn, soybean oils and fish fat, duck fat are good for health. The pig, chicken fat and butter should be moderately eaten. It should be consumed fairly fish fat and vegetable oil in order to regulate the omega 6 and omega 3.
Cardiovascular Diseases ; Fatty Acids