1.Gastric Xanthoma in the Pediatric Population: A Possible Herald for Malignancy?
Joseph D RUSSELL ; Jacquelin PECK ; Claudia PHEN ; Janna L LINEHAN ; Sara KARJOO ; Johnny NGUYEN ; Michael J WILSEY
Pediatric Gastroenterology, Hepatology & Nutrition 2020;23(1):110-114
appetite. Upper endoscopies for both patients revealed small polypoid lesions located in the antrum with foamy histiocytes on histology, leading to the diagnosis of gastric xanthoma.]]>
Abdominal Pain
;
Adult
;
Appetite
;
Child
;
Deglutition Disorders
;
Diagnosis
;
Endoscopy
;
Gastritis
;
Helicobacter pylori
;
Histiocytes
;
Humans
;
Incidental Findings
;
Male
;
Nausea
;
Pediatrics
;
Stomach Neoplasms
;
Vomiting
;
Xanthomatosis
2.Factors affecting emotional eating and eating palatable food in adults
Saniye BILICI ; Busra AYHAN ; Efsun KARABUDAK ; Eda KOKSAL
Nutrition Research and Practice 2020;14(1):70-75
Appetite Questionnaire (EMAQ), and the Palatable Eating Motives Scale (PEMS).RESULTS: A positive significant correlation was observed between the BMI groups and the negative emotions, negative situations, and negative total scores of EMAQ (P < 0.01). The regression results on negative subscales showed that a one unit increase in BMI resulted in a 0.293 unit increase in negative situations scores, a 0.626 unit increase in negative emotions scores, and a 0.919 unit increase in negative total EMAQ scores. When the BMI groups and PEMS subscale scores were examined, a significant relationship was found in the social motives, rewarding, and conformity subscales (P < 0.01). A one unit increase in BMI increased the coping motives scores by 0.077 units.CONCLUSIONS: The emotional states have a significant effect on the eating behavior. On the other hand, an increase in eating attacks was observed, particularly in people who were under the effect of a negative emotion or situation. Nevertheless, there were some limitations of the study in terms of quantitative determination of the effects of this eating behavior depending on the BMI.]]>
Adult
;
Appetite
;
Data Collection
;
Eating
;
Feeding Behavior
;
Female
;
Hand
;
Humans
;
Reward
;
Risk Factors
3.Impact of body mass index on quality of life after distal gastrectomy for gastric cancer
Ki Bum PARK ; Byunghyuk YU ; Ji Yeon PARK ; Oh Kyoung KWON ; Wansik YU
Annals of Surgical Treatment and Research 2019;96(5):250-258
PURPOSE: Few studies have evaluated changes in quality of life (QoL) in relation to changes in body mass index (BMI) after gastrectomy. This study aimed to evaluate the impact of postoperative changes in BMI on QoL after distal gastrectomy in gastric cancer patients. METHODS: QoL data from the European Organization for the Research and Treatment of Cancer (EORTC) gathered via the QLQ-C30 and QLQ-STO22 questionnaires were obtained from 1,036 patients preoperatively and at 1 year postoperatively. The patients were divided into 2 groups: group 1 - decreased postoperative BMI and group 2 - unchanged or increased postoperative BMI. RESULTS: There were 577 patients in group 1 and 459 in group 2. According to global health status and functional scales, emotional functioning (P = 0.035) was significantly worse in group 1 than in group 2 at 1 year postoperatively. Furthermore, there were significant decreases in QoL symptom scale scores, including fatigue (P = 0.016), nausea and vomiting (P = 0.002), and appetite loss (P = 0.001) scores, in group 1 compared with group 2. Regarding QLQ-STO22, reflux symptoms (P = 0.020), anxiety (P = 0.003), and body image (P = 0.003) were significantly worse in group 1 than in group 2 at 1 year after surgery. CONCLUSION: BMI changes after distal gastrectomy influence QoL. Focus on controlling gastrointestinal symptoms and providing psychological support is essential in patients with decreased BMI after surgery. Patients should be offered follow-up care to assist them in maintaining BMI, for example, through dietary-behavior modifications and via intensive nutritional support, to prevent QoL deterioration after distal gastrectomy.
Anxiety
;
Appetite
;
Body Image
;
Body Mass Index
;
Fatigue
;
Follow-Up Studies
;
Gastrectomy
;
Global Health
;
Humans
;
Nausea
;
Nutritional Support
;
Quality of Life
;
Stomach Neoplasms
;
Vomiting
;
Weights and Measures
4.Health-Related Quality of Life, Perceived Social Support, and Depression in Disease-Free Survivors Who Underwent Curative Surgery Only for Prostate, Kidney and Bladder Cancer: Comparison among Survivors and with the General Population.
Dong Wook SHIN ; Hyun Sik PARK ; Sang Hyub LEE ; Seung Hyun JEON ; Seok CHO ; Seok Ho KANG ; Seung Chol PARK ; Jong Hyock PARK ; Jinsung PARK
Cancer Research and Treatment 2019;51(1):289-299
PURPOSE: The purpose of this study was to compare health-related quality of life (HRQoL) of disease-free prostate (PC), kidney (KC), and bladder cancer (BC) survivors with that of the general population. MATERIALS AND METHODS: Our study included 331 urological cancer (UC) survivors (114 PC, 108 KC, and 109 BC) aged ≥ 50 years disease-free for at least 1 year after surgery. The control group included 1,177 subjects without a history of cancer. The HRQoL was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30, the Duke-UNC Functional Social Support Questionnaire, and the Patient Health Questionnaire-9. RESULTS: There was no significant difference between the groups in terms of any of the functioning sub-scales and symptoms, except significantly lower social functioning observed in BC survivors than that observed in KC survivors. Although the three groups of UC survivors showed essentially similar functioning sub-scales and symptoms when compared to the general population, PC and BC survivors showed significantly lower social functioning and a lower appetite than that observed in controls. KC survivors showed lower physical functioning, as well as higher pain and dyspnea. Although all three groups of UC survivors reported higher financial difficulties, they also reported higher perceived social support than that reported by the non-cancer control group. No statistically significant difference was observed in terms of depressive symptoms between each group of UC survivors and the general population. CONCLUSION: Disease-free survivors of the three major types of UCs showed generally similar HRQoL compared to the general population, as well as compared to each other.
Appetite
;
Depression*
;
Dyspnea
;
Humans
;
Kidney Neoplasms
;
Kidney*
;
Prostate*
;
Prostatic Neoplasms
;
Quality of Life*
;
Survivors*
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*
;
Urologic Neoplasms
5.Co-infection of Dirofilaria immitis and Japanese encephalitis virus in a spotted seal (Phoca largha) in the Republic of Korea
Ji Youl JUNG ; Hyun Jeong KIM ; Kyunghyun LEE ; Jun Gu CHOI ; Yeon Hee KIM ; Kyoung Ki LEE ; Young dae KIM ; ByungJae SO ; Hae Eun KANG ; Eun Jin CHOI
Journal of Veterinary Science 2019;20(6):e65-
A 10-year-old male spotted seal presented with loss of appetite and decreased activity. Grossly, the internal organs revealed several filarial nematodes in the right ventricle of the heart and the pulmonary vessels. Histopathological examination of the brain revealed moderate nonsuppurative meningoencephalitis with glial nodules and neuronophagia. Japanese encephalitis virus (JEV) of genotype I was isolated from the brain. All nematodes were identified as Dirofilaria immitis. This is the first clinical case of co-infection with D. immitis and JEV in a seal, suggesting that the seal, may be a dead-end host, like the human and horse, for JEV.
Appetite
;
Asian Continental Ancestry Group
;
Brain
;
Child
;
Coinfection
;
Dirofilaria immitis
;
Dirofilaria
;
Encephalitis Virus, Japanese
;
Encephalitis, Japanese
;
Genotype
;
Heart
;
Heart Ventricles
;
Horses
;
Humans
;
Male
;
Meningoencephalitis
;
Republic of Korea
6.Factors associated with treatment interruption in elderly patients with cancer.
Hye Sung WON ; Der Sheng SUN ; Ji Young CHOI ; Ho Jung AN ; Yoon Ho KO
The Korean Journal of Internal Medicine 2019;34(1):156-164
BACKGROUND/AIMS: This study was conducted to identify risk factors that predict vulnerability to cancer therapy on the basis of the clinical, geriatric, and quality of life assessment before starting treatment in elderly patients. METHODS: Seventy-five patients aged 65 years and over with newly diagnosed stage IV solid cancer receiving chemotherapy were analyzed. Clinical and laboratory data were collected. The geriatric assessment was performed using the Korean versions of the Modified Barthel Index, Instrumental Activities of Daily Living, Mini-Mental State Examination, and Geriatric Depression Scale. The European Organisation for Research and Treatment of Cancer Quality-of-Life Core Questionnaire (EORTC-QLQ-C30) was also performed. RESULTS: Forty-one patients stopped cancer treatment during or after the end of first-line therapy and were classified as the treatment interruption group. By univariate analysis, treatment interruption was associated with metastases to ≥ 2 distant sites, lower albumin level, lower EORTC-QLQ-C30 physical and role functioning scores, and higher EORTC-QLQ-C30 fatigue and appetite loss symptom scores. By multivariate analysis, treatment interruption was significantly associated with low score for the EORTC-QLQ-C30 physical functioning scale (odds ratio [OR], 1.020; 95% confidence interval [CI], 1.002 to 1.039; p = 0.030), and ≥ 2 sites of distant metastases (OR, 2.965; 95% CI, 1.012 to 8.681; p = 0.047). CONCLUSIONS: The EORTC-QLQ-C30 physical functioning score and metastases to ≥ 2 organs, which indicate a poor physical functional status and metastatic high tumor burden, were significantly associated with interruption of first-line treatment in elderly patients with cancer.
Activities of Daily Living
;
Aged*
;
Appetite
;
Depression
;
Drug Therapy
;
Fatigue
;
Geriatric Assessment
;
Humans
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Quality of Life
;
Risk Factors
;
Tumor Burden
7.Effects of CeA lesions on the initiation and expression of sodium appetite in sodium-deficient rats.
Zhi Xin ZHAO ; Ying Ying LIAO ; Yuan Yuan FAN ; En She JIANG
Chinese Journal of Applied Physiology 2019;35(1):13-18
OBJECTIVE:
To investigate the effects of central nucleus of amygdala (CeA) lesion on the initiation and expression of sodium appetite in sodium-deficient rats.
METHODS:
Three groups of SD rats (n=6 in each group) were treated with bilateral CeA lesion, sham lesion or no lesion. After the recovery, the rats were fed with low-sodium diets for 14 days to establish a sodium-deficient rat model. The double-bottle selection in single cage test was used to observe the intake of 0.3 mol/L NaCl and DW in 5 timepoint with 24 hours in sodium-deficient rats. Immunofluorescence staining of aldosterone-sensitive neurons in the nucleus tractus solitarii (NTS)was used to investigate the effect of CeA lesion or not on the activity of aldosterone-sensitive neurons in rats with or without sodium deficiency.
RESULTS:
After fed with low-sodium diet for14 days, the volume and preference rate of 0.3 mol/L NaCl intake of the rats within 24 h were significantly increased compared with those before low-sodium diet (P<0.01). The intake volume and the preference rate of 0.3 mol/L NaCl in CeA lesion rats were significantly decreased than those in CeA sham lesion rats and normal rats in the sodium-deficient condition (P<0.01). The CeA lesion had no effects on the activity of aldosterone-sensitive neurons in NTS in rats with low-sodium diet.
CONCLUSION
Low-sodium diet induces an increase in the expression of sodium appetite in rats. CeA lesions inhibit the behavioral expression of sodium appetite in sodium-deficient rats but have no effects on the initiation of sodium appetite in rats with sodium-deficient rats.
Amygdala
;
pathology
;
Animals
;
Appetite
;
Diet, Sodium-Restricted
;
Neurons
;
Rats
;
Rats, Sprague-Dawley
;
Sodium
;
Sodium, Dietary
;
pharmacology
8.Relationship between Dietary Behaviors and Life Stress of Middle School Students in Gyeonggi Area
Kyung Ae PARK ; Myoung Sook LEE ; Kyung Hee SONG
Korean Journal of Community Nutrition 2019;24(5):384-394
OBJECTIVES: The study was performed to examine the dietary behaviors and life stress of middle school students in the Gyeonggi area. METHODS: A total of 580 middle school students (295males, 285 females) in the Gyeonggi area participated in the study between July and August in 2011. The study was a questionnaire-based survey that included dietary habits, dietary behaviors, and life stress. RESULTS: For dietary habits, the score for drinking milk was higher in male students than in female students, whereas the score for eating fruits was higher in female students compared to male students. There were significant differences in foods eaten and preferred under stress between male and female students. Male students showed significantly less changes in the number of meals, amount of meal intake, number of snacks, snack intake, frequency of overeating, and appetite during stress than female students. Life stress score of students largely came from academic factors, and female students showed higher stress levels in personal and surrounding environment factors than male students. Life stress score was significantly lower in students with high and moderate levels of dietary habits than in students with a low level of dietary habits. Total score for dietary habits and scores for eating adequate amounts of foods for each meal, considering a combination of food groups at each meal and eating green and orange vegetables, were significantly negatively correlated with life stress score. Life stress score was significantly negatively correlated with meal regularity and positively with the level of overeating. CONCLUSIONS: This study may provide basic information on dietary habits and life stress according to gender and the relationship between dietary behaviors and life stress of middle school students, and it suggests gender-based nutrition education programs to solve undesirable dietary habits and dietary behaviors in students with higher stress.
Appetite
;
Citrus sinensis
;
Drinking
;
Eating
;
Education
;
Female
;
Food Habits
;
Fruit
;
Gyeonggi-do
;
Humans
;
Hyperphagia
;
Male
;
Meals
;
Milk
;
Snacks
;
Stress, Psychological
;
Vegetables
9.Anxiety and Depression of the Patients with Hematological Malignancies during Hospitalization for Hematopoietic Stem Cell Transplantation
Ho Jun SEO ; Young Gun BAEK ; Byung Sik CHO ; Tae Suk KIM ; Yoo Hyun UM ; Jeong Ho CHAE
Psychiatry Investigation 2019;16(10):751-758
OBJECTIVE: This study aimed to assess the anxiety and depression in patients undergoing hematopoietic stem cell transplantation (HSCT). METHODS: Eighty-seven adult patients with various hematologic diseases, who were scheduled to receive autologous or allogeneic HSCT, were enrolled. The M.D. Anderson Symptom Inventory and the Hospital Anxiety Depression Scale were applied prospectively at hospital admission (D-14), on the day of transplantation (D day), and at 7 (D7) and 14 days (D14) after transplantation. RESULTS: The severity of both anxiety and depressive symptoms increased over time, with a peak at D7, and then showed a downturn at D14. Physical distresses also started with mild intensity at base line, which were continuously aggravated until D7, and then a partial recovery afterwards. Approximately, 52% of the participants had significantly high anxiety or depression before the start of HSCT. The occurrence of aggravation of pain, nausea, shortness of breath, and lack of appetite was associated with the development of anxiety during isolation period. The patients with significant baseline anxiety had higher scores on fatigue and shortness of breath items at D7 compared to those without. CONCLUSION: Our finding suggests the importance of psychiatric approaches, including preventive measures, for the patients undergoing HSCT.
Adult
;
Anxiety
;
Appetite
;
Depression
;
Dyspnea
;
Fatigue
;
Hematologic Diseases
;
Hematologic Neoplasms
;
Hematopoietic Stem Cell Transplantation
;
Hematopoietic Stem Cells
;
Hospitalization
;
Humans
;
Nausea
;
Prospective Studies
10.An Autochthonous Human Case of Fasciolopsiasis in Nepal
Ranjit SAH ; Michele CALATRI ; Rafael TOLEDO
The Korean Journal of Parasitology 2019;57(3):295-298
Fasciolopsiasis is rarely known as the parasitic disease in Nepal. Herein, we report a case of fasciolopsiasis in a 22-year-old man who was admitted in the hospital with abdominal pain, distension and loss of appetite for a month. He had previously diagnosed with acute viral hepatitis but, his abdominal pain was not resolving despite improvement in his liver function and general condition. During endoscopy an adult digenean worm was seen in the first part of the duodenum. After isolation, the worm was identified morphologically as Fasciolopsis buski. Microscogic examination of the patient’s stool revealed eggs with a morphology consistent with F. buski. Eggs were yellow-brown, ellipsoidal, unembmbryonated, operculated, filled with yolk cells, with thin shell and ranging 118–130 μm in length and 60–69 μm in width. The abdominal pain of the patient was resolved after treatment with praziquantel. By the present study, it was confirmed for the first time that fasciolopsiasis is indigenously transmitted in Nepal. Accordingly, the epidemiological studies in humans and reservoir host animals should be performed intensively in near future.
Abdominal Pain
;
Adult
;
Animals
;
Appetite
;
Duodenum
;
Eggs
;
Endoscopy
;
Epidemiologic Studies
;
Fasciolidae
;
Hepatitis
;
Humans
;
Liver
;
Nepal
;
Ovum
;
Parasitic Diseases
;
Praziquantel
;
Trematode Infections
;
Young Adult

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