1.Prevalence, multidrug resistance, and biofilm formation of Vibrio parahaemolyticus isolated from fish mariculture environments in Cat Ba Island, Vietnam
Kim Cuc Thi NGUYEN ; Phuc Hung TRUONG ; Hoa Truong THI ; Xuan Tuy HO ; Phu Van NGUYEN
Osong Public Health and Research Perspectives 2024;15(1):56-57
Objectives:
Vibrio parahaemolyticus is a major foodborne pathogen in aquatic animals and a threat to human health worldwide. This study investigated the prevalence, antimicrobial resistance, antimicrobial resistance genes (ARGs), and biofilm formation of V. parahaemolyticus strains isolated from fish mariculture environments in Cat Ba Island, Vietnam.
Methods:
In total, 150 rearing water samples were collected from 10 fish mariculture farms in winter and summer. A polymerase chain reaction assay was used to identify V. parahaemolyticus, its virulence factors, and ARGs. The antimicrobial resistance patterns and biofilm formation ability of V. parahaemolyticus strains were investigated using the disk diffusion test and a microtiter plate-based crystal violet method, respectively.
Results:
Thirty-seven V. parahaemolyticus isolates were recovered from 150 samples. The frequencies of the tdh and trh genes among V. parahaemolyticus isolates were 8.1% and 21.6%, respectively. More than 90% of isolates were susceptible to ceftazidime, cefotaxime, and chloramphenicol, but over 72% were resistant to ampicillin, tetracycline, and erythromycin. Furthermore, 67.57% of isolates exhibited multidrug resistance. The presence of ARGs related to gentamicin (aac(3)-IV), tetracycline (tetA) and ciprofloxacin (qnrA) in V. parahaemolyticus isolates was identified. Conversely, no ARGs related to ampicillin or erythromycin resistance were detected. Biofilm formation capacity was detected in significantly more multidrug-resistant isolates (64.9%) than non-multidrug-resistant isolates (18.9%).
Conclusion
Mariculture environments are a potential source of antibiotic-resistant V.parahaemolyticus and a hotspot for virulence genes and ARGs diffusing to aquatic environments. Thus, the prevention of antibiotic-resistant foodborne vibriosis in aquatic animals and humans requires continuous monitoring.
2.Knowledge, attitude and practice on the use of vietnamese medicinal plants for common diseases treatment among people in Phu Vang district, Thua Thien Hue province
Van Hung NGUYEN ; Thi Cam Quy TRUONG ; Xuan Vu NGUYEN ; Duc Hieu NGUYEN ; Thi Vui HUYNH ; Thi Ha Nhi TANG ; Thi Ngoc Giao LE ; Thanh Tu TRUONG ; Dinh Tuyen HOANG ; Dinh Hue LE
Hue Journal of Medicine and Pharmacy 2023;13(7):75-82
Background: Vietnamese herbs are considered as a botanical resource, a precious medicinal source of our country, and are widely used in the residential community in general. Phu Vang district is a coastal plain and lagoon in Thua Thien Hue province, where people’s living standards are not high, health facilities lack equipment. Therefore, the needs for primary health care are necessary to be strengthened, especially in the treatment of common diseases using Vietnamese herbs to reduce costs and improve health for the people. However, the knowledge of the local residents about Vietnamese herbs preventing and treating common diseases at home has not been surveyed. Objectives: (1) To describe the knowledge, attitude and practice on the use of Vietnamese herbs used in the treatment of common diseases of residents in some communes of Phu Vang district. (2) To determine some factors related to the use of Vietnamese herbs in the treatment of common diseases among the residents. Methods: A cross-sectional study was conducted on 400 residents representing the heads of households in three communes of Phu Vang district, Thua Thien Hue province, Thua Thien Hue province. Descriptive statistical analysis and multivariable logistic regression were performed with SPSS software. Results: Knowledge: Good: 45.2%; Fair: 30.8%; Average: 9.0%; Poor: 2.0%. Attitude: 97.0% of residents preferred using Vietnamese herbs in the treatment of common diseases, and 96.6% of residents agreed to continue using Vietnamese herbs to treat similar diseases later. Practice: Good: 7.8%; Fair: 16.7%; Average: 25.3%; Poor: 50.2%. Receiving information about Vietnamese herbs and growing them at home gardens were two factors related to the use of Vietnamese herbs to treat common diseases (p < 0.05). Conclusion: The practice of using Vietnamese herbs to treat common diseases of the residents in Phu Vang district is still low, it is necessary to strengthen educational propaganda to raise the awareness and practice among residents on the prevention and treatment of diseases with Vietnamese herbs at home.
3.Efficacy of insecticide treated hammock nets (ITHNS) on forest malaria control in Vietnam
Hung Xuan Le ; Thang Duc Ngo ; Xa Xuan Nguyen
Journal of Medical Research 2007;49(3):103-108
Background: Forest malaria is one of the challenges faced by the Malaria Control Program in Vietnam. Objectives: (1). To evaluate the malaria prevalence among forest goers, (2). To study the efficacy of insecticide-treated hammock net (ITHNs) in malaria prevention for forest goers. Subject and method: The descriptive epidemiological intervention study on the effect of ITHNs in forest malaria control has been carried out in Ninh Thuan in 2005 \ufffd?2006. Results: Malaria prevalence among forest goers was very high: Clinical malaria: 15.5%, enlarged spleen: 7.0%, confirmed cases: 13.3% and asymptomactic cases: 74%. Age, sex, ethnic, low educated levels, low income, less use of mosquito-nets and poor house condition were considered as risk factors in malaria infection, especially for people who spent much time in the forest. ITHNs were effective in prevention of malaria infection, the malaria morbidity was decreased after 2 years of application (reduced from 31 % to 14% for prevalence, and from 274/1000 population to 161/1000 population for incidence), and the morbidity rate was lower than that in the group of people who did not use ITHNs. Conclusion: For the entomological survey, it is found that Anopheles density reduced in the group of people prevented by ITHNs. The residual of insecticide on the hammock net was decreased after 2 years utilization.\r\n', u'\r\n', u'\r\n', u'
Malaria
4.Laparoscopic surgery in Quang Tri General Hospital
Thanh Van Le ; Viet Khanh Phan ; Hung Nam Tran ; Dung Xuan Nguyen ; Quang Phuoc Hoang
Journal of Surgery 2007;57(1):24-29
Background: Laparoscopic cholecystectomy is the first laparoscopic surgery that was performed at Cho Ray hospital in September 1992. In 2005, Quang Tri general hospital has performed successfully the first case of laparoscopic appendectomy. Objectives: To access the preliminary results of application on endoscopic surgery in Quang Tri general hospital. Subjects and method: A prospective study was conducted on 140 patients with laparoscopic surgery or retroperitoneal surgery, was performed in Quang Tri general hospital from September, 2005 to April, 2006. Results:Among 140 patients was operated, there was only one case of postoperative intestinal obstructive complication (accounted for 0.7%), no case of death. Operative aged was between 11 and 70 years old. The average surgical time was 65 minutes for cholecystectomy, 35 minutes for appendectomy, 85 minutes for ureterolithotomy, 80 minutes for gynecological diseases. 2 cases of cholecystectomy and appendectomy changed open surgery. Conclusion: Laparoscopic surgery is a safe and effective method. It can be developed in provincial hospitals. Quang Tri general hospital has successful preliminary developed the new technique.
Laparoscopy
;
5.Evaluating clinical experience from a case of hepatocellular carcinoma with combinated therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology
Long Cong Nguyen ; Truong Xuan Bui ; Thong Minh Pham ; Ho Thi Thu Pham ; Hung Quoc Nghiem ; Phuong Minh Tran ; Long Van Dao ; Trach Khanh Nguyen
Journal of Medical Research 2007;47(2):69-73
Background: Hepatocellular carcinoma (HCC) is the most common primary hepatic tumor and one of the most common cancers worldwide. HCC is a primary malignancy of hepatocellular origin. Objectives:The aim of study is to combinate therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology. Subjects and method: A 50 years old male patient with hepatocellular carcinoma having a diameter of tumor more than 5 cm was treated by combination of transarterial chemoembolization and percutaneous ethanol injection from December 2000. Results & Conclusion: Results of study showed that: Transarterial chemoembolization and percutaneous ethanol injection are the two of non-surgical methods for treatment of hepatocellular carcinoma which are most commonly available in applied clinical activities at present. Up to now, the patient's life expectancy after therapy is more than 6 years that means the result of treatment is very good. However, the emerging metatasis into the anterior-right-Iower chest wall that was caused by fine needle aspiration cytology should be reviewed for further evaluating clinical experience, especially in cases with quite clear imaging features of untrasonography and significantly elevated AFP level higher than 200 ng/rnl.
Carcinoma
;
Hepatocellular/ pathology
;
therapy
6.Study on "Information - Education and Communication (IEC)" and "knowledge - attitude and practice (KAP)" of community on malaria and its control after intervention of health education
Hung Xuan Le ; Hung Manh Nguyen
Journal of Malaria and parasite diseases Control 2004;0(3):3-9
Background: Since 1991-2000, the prevalence of malaria is reduced remarkably in Vietnam. The malaria related mortality reduced 98%. Objective: To evaluate effect of health education in malaria control for ethnic minority people. Subject and Method: The study was carried out in 4 districts: Hoang Su Phi and Quan Ba (Ha Giang); Ia grai and K'Bang (Gia Lai). Qualitative and quantitative method was used in this study. Results: The findings of the study after 2 years showed that the Information - Education and Communication (IEC) is increased in 2007. The proportion of the households have radio, TV, leaflets/pictures is higher than year 2005: 39.1 %, 60.0% and 6.3%. The number of people were communicated about malaria is increased by 61%. The most information channel that the people received is from health staff (93%); from radio and TV: 22.5 and 25.6%. People know the right cause and its prevention of malaria is increased 55% in 2005 to 80% in 2007. The proportion of bed net coverage among community is increased, the number of bed net per households is 2.8 and number of people per bed net is 2.2. Conclusion: Almost people in this study site desired to utilize bed net: 99%. About 88.3% (2005) and 87.5% (2007) of people utilized the public health service when they get sick. After two years of health education intervention, the malaria morbidity in the study site is reduced remarkably by 45 - 50%.
Malaria
;
IEC
;
ethnic minority
7.Low awareness of malaria among the raglai ethnic minority group living in the mountainous province of Ninh Thuan, Vietnam
Xa Xuan Nguyen ; Hung Xuan Le ; Thang Duc Ngo ; Koen Peeters ; Annette Erhart ; Joan Muela Ribera ; Umberto D' Alessandro
Journal of Malaria and parasite diseases Control 2004;0(3):39-43
Background: The vulnerability to contract malaria was researched among the Raglai ethnic minority population living in the mountainous areas of Ninh Thuan province, South-central Viet Nam, one of the areas with highest incidence rates in the country. Objective: To investigate the bed net use, risk perception of contracting malaria in Raglai ethnic minority. Subject and Method: The study used qualitative and quantitative method and was carried out in Ninh Thuan from 8/2005 to 8/2006. Result: Raglai exposure to malaria was related to farmers' forest activity and forest sleep which were directly related to the combination of sleeping and living in a government supported home in newly established villages along the road with a second home or reduced plot hut near fields in the forest to meet work requirements during the labor intensive malaria transmission and rainy season. In this context, access to health care, bed net use, risk perception of contracting malaria and health seeking behavior were researched. Conclusion: The results of the study do not only show the vulnerability of an impoverished ethnic minority population but as well the urgent need to better understand ethnic minorities' social context and culture to improve malaria control strategies.
Awareness of malaria
;
ethnic minority
;
Ninh Thuan province
;
bed net use
8.The necessity to have unified solution in the expanding of realization of policies and strategies
Pharmaceutical Journal 2003;326(6):4-5
In recent years, various resolutions and decisions issued by the Party and the Government concerning the Health care and Pharmacy, especially the Decision No 37/TTg from the Prime Minister regarding “National Policy on the medicaments” dated June 20/1996, Decision No 35/TTg dated March 19/2001 on the “Strategy of People’s health care and protection in the period of 2001-2010” and the Decision No 108/TTg dated August 15/2002 on the “Strategy of the Development of Pharmacy in the period till the year 2010”. In general, all addressed the present problems of the Pharmacy. Negligence must not be taken them. It is necessary to organize a steering Board responsible for these strategies and policies, with the participation of some aiding permanent team. In every locations, steering office must be organized for effectively implementing
Health Policy
;
Delivery of Health Care
;
Pharmacy
9.Some opinions of treatment of rectal cancer in Viet Duc hospital during 1989-1996
Journal of Vietnamese Medicine 2002;269(2):25-31
A study on 206 patients (mal: 48%) with ages of 40-60 has shown that most frequent signs were feces with blood and mucus and dyspepsia. 98% of cancers were adenocarcinoma. 7% of tumors located in the 1/3 above rectum, 34% of tumors located in the 1/3 middle rectum and 59% of tumors located in the 1/3 lower rectum. The treatment involved the temporary operation (21%), partial rectal removal operation (19%) and complete rectal removal operation (48.5%). The postoperative complications included mortality (1.5%), peritoneal fistula or peritonitis (13%), bleeding (0.5%). The survival rate after 5 years (29%) in which Dukes B phase (45%), Dukes C phase (11%). The rectal cancer is common disease, diagnosed and treated lately.
Therapeutics
;
Rectal Neoplasms
10.The clinical, endoscopic and histopathological features of the rectal-sigma colorectal polyp
Journal of Practical Medicine 2002;435(11):30-34
175 patients with 224 rectal sigma colorectal-polyps in ages of 18 months - 77 ages were found by the endoscopy or the rectal-colorectal operation. The ratio of male/female was 1.92. The main and mark symptom is movement total blood (86.3%) single polyp: 80.8%, the small and medium polyps: 87%, polyps with peduncle: 67.9%, gland polyp: 70.9%, polyp changed to cancer: 7.6%.The large polyps without peduncle, with rough surface account for the severe displasia and high rate of changing to cancer
Colorectal Neoplasms, Hereditary Nonpolyposis

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