18F-FDG PET/CT is one of the most advanced diagnostic methods for lymphoma, which plays an important role in the diagnosis, efficacy evaluation, prognosis prediction and clinical decision-making of lymphoma. Radiomics, which uses complex bioinformatics methods to extract quantitative information from medical images to characterize tumor heterogeneity, has blossomed over the past decade. Radiomics has been applied to 18F-FDG PET/CT to quantify the heterogeneity within tumors, which has great potential and value in the study of lymphoma. This article reviews the research progress and application of 18F-FDG PET/CT radiomics in lymphoma.