Bioactive glass(BG)has been used as a candidate for bone and soft tissue repair materials because of its compatibility,bioactivity and ability to form a crystalline hydroxyapatite layer.This paper introduces the mechanism of BG ion release,discusses the application of borosilicate bioactive glass(BBG)in bone and soft tissue repair,and provides an overview of the potential and clinical translational challenges faced by BBG in bone cement,scaffold,hydrogel,and fiber research applications.