1.Quantitative MRI Assessment of Pancreatic Steatosis Using Proton Density Fat Fraction in Pediatric Obesity
Jisoo KIM ; Salman S. ALBAKHEET ; Kyunghwa HAN ; Haesung YOON ; Mi-Jung LEE ; Hong KOH ; Seung KIM ; Junghwan SUH ; Seok Joo HAN ; Kyong IHN ; Hyun Joo SHIN
Korean Journal of Radiology 2021;22(11):1886-1893
Objective:
To assess the feasibility of quantitatively assessing pancreatic steatosis using magnetic resonance imaging (MRI) and its correlation with obesity and metabolic risk factors in pediatric patients.
Materials and Methods:
Pediatric patients (≤ 18 years) who underwent liver fat quantification MRI between January 2016 and June 2019 were retrospectively included and divided into the obesity and control groups. Pancreatic proton density fat fraction (P-PDFF) was measured as the average value for three circular regions of interest (ROIs) drawn in the pancreatic head, body, and tail. Age, weight, laboratory results, and mean liver MRI values including liver PDFF (L-PDFF), stiffness on MR elastography, and T2* values were assessed for their correlation with P-PDFF using linear regression analysis. The associations between P-PDFF and metabolic risk factors, including obesity, hypertension, diabetes mellitus (DM), and dyslipidemia, were assessed using logistic regression analysis.
Results:
A total of 172 patients (male:female = 125:47; mean ± standard deviation [SD], 13.2 ± 3.1 years) were included. The mean P-PDFF was significantly higher in the obesity group than in the control group (mean ± SD, 4.2 ± 2.5% vs. 3.4 ± 2.4%; p = 0.037). L-PDFF and liver stiffness values showed no significant correlation with P-PDFF (p = 0.235 and p = 0.567, respectively). P-PDFF was significantly associated with obesity (odds ratio 1.146, 95% confidence interval 1.006–1.307, p = 0.041), but there was no significant association with hypertension, DM, and dyslipidemia.
Conclusion
MRI can be used to quantitatively measure pancreatic steatosis in children. P-PDFF is significantly associated with obesity in pediatric patients.
2.Key imaging features for differentiating cystic biliary atresia from choledochal cyst: prenatal ultrasonography and postnatal ultrasonography and MRI
Hyun Joo SHIN ; Haesung YOON ; Seok Joo HAN ; Kyong IHN ; Hong KOH ; Ja-Young KWON ; Mi-Jung LEE
Ultrasonography 2021;40(2):301-311
Purpose:
This study compared clinical and radiologic differences between cystic biliary atresia (cBA) and choledochal cyst (CC) type Ia/b.
Methods:
Infants (≤12 months old) who were diagnosed with cBA or CC type Ia/b from 2005 to 2019 were retrospectively reviewed. Imaging features on preoperative ultrasonography (US) and magnetic resonance imaging (MRI) were compared between the cBA and CC groups. Logistic regression and area under the receiver operating characteristic curve (AUC) analyses were performed for the diagnosis of cBA. Changes in cyst size were also evaluated when prenatal US exams were available.
Results:
Ten patients (5.5% of biliary atresia cases) with cBA (median age, 48 days) and 11 infants with CC type Ia/b (Ia:Ib=10:1; median age, 20 days) were included. Triangular cord thickness on US (cutoff, 4 mm) showed 100% sensitivity and 90.9% specificity (AUC, 0.964; 95% confidence interval [CI], 0.779 to 1.000) and cyst size on MRI (cutoff, 2.2 cm) had 70% sensitivity and 100% specificity (AUC, 0.900; 95% CI, 0.690 to 0.987) for diagnosing cBA. Gallbladder mucosal irregularity on US and an invisible distal common bile duct on MRI were only seen in the cBA group (10 of 10). Only the CC group showed prenatal cysts exceeding 1 cm with postnatal enlargement.
Conclusion
Small cyst size (<1 cm) on prenatal US, triangular cord thickening (≥4 mm) and gallbladder mucosal irregularity on postnatal US, and small cyst size (≤2.2 cm) and an invisible distal common bile duct on MRI can discriminate cBA from CC type Ia/b in infancy.
3.Endovascular Treatment of a Lumbar Spinal Epidural Arteriovenous Fistula with Radiculopathy:A Case Report
Hyun HWANG ; Jae Ho SHIN ; Jae Taek HONG ; Yon Kwon IHN
Journal of the Korean Radiological Society 2021;82(6):1628-1633
Spinal epidural arteriovenous fistulas (SEDAVFs) are rare spinal vascular malformations that are difficult to diagnose and treat. SEDAVFs can be asymptomatic; however, symptoms can arise from the compression of adjacent nerve roots by dilated vein and perimedullary venous reflux, caused by shunting into the epidural venous plexus. A 31-year-old male presented to our institution with a 2-year history of progressively worsening low-back pain, radiating thigh pain, and sensory changes in his lower extremities. MRI and CT angiography demonstrated dilated epidural vascular lesion compressing the nerve root. The SEDAVF was embolized with multiple coils, which alleviated the nerve root compression from the engorged venous varix and improved the patient’s radiculopathy. Our experience from this case shows that endovascular coil embolization using the transarterial approach can be an effective treatment for SEDAVF and an alternative to surgical ligations.
4.Mucosa-Associated Lymphoid Tissue Lymphoma of the Cheek Mimicking Benign Entities: a Case Report
Hyun HWANG ; Jae Ho SHIN ; Yon Kwon IHN ; Sungjun HAN ; Hong Sik PARK
Investigative Magnetic Resonance Imaging 2021;25(2):129-134
The prevalence of cheek lymphoma, especially a mucosa-associated lymphoid tissue lymphoma (MALT), is very rare. Non-specific symptoms and image findings of cheek lymphoma may mimic benign entities and make it difficult to diagnose. In this case report, we present a case of MALT lymphoma of the cheek mimicking benign entities on computed tomography and magnetic resonance imaging.
5.Mucosa-Associated Lymphoid Tissue Lymphoma of the Cheek Mimicking Benign Entities: a Case Report
Hyun HWANG ; Jae Ho SHIN ; Yon Kwon IHN ; Sungjun HAN ; Hong Sik PARK
Investigative Magnetic Resonance Imaging 2021;25(2):129-134
The prevalence of cheek lymphoma, especially a mucosa-associated lymphoid tissue lymphoma (MALT), is very rare. Non-specific symptoms and image findings of cheek lymphoma may mimic benign entities and make it difficult to diagnose. In this case report, we present a case of MALT lymphoma of the cheek mimicking benign entities on computed tomography and magnetic resonance imaging.
6.Radiologic Findings in Extrapancreatic Solid Pseudopapillary Tumor with Aggressive Behavior: a Case Report.
Hye Won CHOI ; Hyun Jeong PARK ; Soon Auk HONG ; Sung Bin PARK ; Eun Sun LEE ; Hye Shin AHN ; Jong Beum LEE ; Byung Ihn CHOI
Journal of Korean Medical Science 2017;32(12):2079-2084
Solid pseudopapillary tumor (SPT) is a low grade malignant tumor in the pancreas, and extrapancreatic SPT is extremely rare. We report a case of a 61-year-old woman who complained abdominal pain with diffuse tenderness. She was diagnosed with extrapancreatic SPT with extensive peritoneal dissemination and hepatic metastases. Although a few cases have reported imaging findings of extrapancreatic SPT, there have been no reports of extrapancreatic SPT with aggressive tumor behavior and dismal prognosis. Although imaging features closely resembled those of classical pancreatic SPTs, malignant transformation of extrapancreatic SPT should be considered when focal discontinuity of the tumor capsule with ill-defined margin and invasion of adjacent structures were identified.
Abdominal Pain
;
Female
;
Humans
;
Middle Aged
;
Neoplasm Metastasis
;
Pancreas
;
Prognosis
;
Ultrasonography
7.A Case of a Patient with Both Chorea and Restless Legs Syndrome.
Yoon Kyung SHIN ; Seung Chul HONG ; Yon Kwon IHN ; Jong Hyun JEONG ; Jin Hee HAN ; Sung Pil LEE
Journal of Korean Medical Science 2008;23(3):533-536
The patient was a 44-yr-old man with end-stage renal disease who had developed chorea as a result of hypoglycemic injury to the basal ganglia and thalamus and who was subsequently diagnosed with depression and restless legs syndrome (RLS). For proper management, the presence of a complex medical condition including two contrasting diseases, chorea and RLS, had to be considered. Tramadol improved the pain and dysesthetic restlessness in his feet and legs, and this was gradually followed by improvements in his depressed mood, insomnia, lethargy, and feelings of hopelessness. This case suggests that the dopaminergic system participates intricately with the opioid, serotoninergic, and noradrenergic systems in the pathophysiology of RLS and pain and indirectly of depression and insomnia.
Adult
;
Analgesics, Opioid/therapeutic use
;
Anti-Dyskinesia Agents/therapeutic use
;
Chorea/*complications/pathology
;
Citalopram/therapeutic use
;
Drug Therapy, Combination
;
Haloperidol/therapeutic use
;
Humans
;
Kidney Failure, Chronic/*complications
;
Magnetic Resonance Imaging
;
Male
;
Restless Legs Syndrome/*complications/drug therapy/pathology
;
Serotonin Uptake Inhibitors/therapeutic use
;
Tramadol/therapeutic use
8.Giant aneurysm and fistula fed by multiple arteries and draining into the pulmonary artery: detection by 64-multidetector coronary CT angiography.
Jeong Hwan CHO ; Jong Seon PARK ; Ihn Ho CHO ; Dong Gu SHIN ; Bong Sup SHIM ; Geu Ru HONG ; Young Jo KIM
Korean Journal of Medicine 2008;75(6):656-657
No abstract available.
Aneurysm
;
Angiography
;
Arteries
;
Fistula
9.Hypertrophic Cardiomyopathy Complicated by Left Ventricular Apical Necrosis and Aneurysm in a Young Man: FDG-PET Findings.
Jong Seon PARK ; Ihn Ho CHO ; Dong Gu SHIN ; Young Jo KIM ; Gu Ru HONG ; Bong Sup SHIM
The Korean Journal of Internal Medicine 2007;22(1):28-31
A 29-year old male was transferred to our hospital with an abnormal chest X-ray finding diagnosed as hypertrophic cardiomyopathy with apical necrosis and aneurysm formation. Four years after the initial hospitalization, we confirmed the aneurysm and necrosis using both integrated positron emission tomography (PET) and computed tomography (CT) scanning. The F-18 2-fluoro-2-deoxy-D-glucose (FDG) PET/CT enabled precise localization of the aneurysm, which was found to be composed of semi-lunar calcification of non-metabolic myocardium. A contrast-enhanced CT angiography showed an hour-glass appearance of the left ventricular cavity. The integrated PET/CT fusion scanner is a novel multimodality technology that allows for a comprehensive analysis of the anatomical and functional status of complex heart disease. Based on these findings, long standing mechanical and physiologic abnormalities may have led to chronic ischemia in the hypertrophied myocardium, induced necrosis and calcification at the cardiac apex.
Tomography, X-Ray Computed
;
Positron-Emission Tomography
;
Necrosis/complications/*diagnosis
;
Male
;
Humans
;
Heart Ventricles/*pathology
;
Heart Aneurysm/complications/*diagnosis
;
Fluorodeoxyglucose F18/diagnostic use
;
Contrast Media
;
Cardiomyopathy, Hypertrophic/complications/*diagnosis
;
Angiography, Digital Subtraction
;
Adult
10.Scintigraphic Evaluation of Inhalation Injury in Fire Victims.
Kyung Ah CHUN ; Ihn Ho CHO ; Gyu Jang WON ; Hyung Woo LEE ; Kyung Chul SHIN ; Jin Hong JEONG ; Gwan Ho LEE
Nuclear Medicine and Molecular Imaging 2006;40(1):28-32
PURPOSE: Conventional chest X-ray and pulmonary function test cannot sensitively detect inhalation injury. Bronchoscopy is known to be the gold standard but it is invasive method. We evaluated whether lung inhalation/perfusion scans can sensitively detect inhalation injury of fire victims. MATERIALS AND METHODS: Nineteen patients (male 9, female 10, mean age 31.6 yr) of fire victims were enrolled in this study. Inhalation lung scan was performed 2 days later after inhalation injury with 99mTc-technegas. Perfusion lung scan was performed 4 days later with 99mTc-MAA (macroaggregated albumin). Follow up lung scans were performed 16 and 18 days later for each. Chest X-ray was performed in all patients and bronchoscopy was performed in 17 of 19 patients at the same period. Pulmonary function test was performed in 9 patients. RESULTS: Four of 19 patients showed inhalation and perfusion defects and one showed inhalation defect but, normal perfusion scan findings. These five patients with abnormal scan findings showed abnormal bronchoscopic findings and severe respiratory symptoms. On chest X-ray, 2 of them had pulmonary tuberculosis and one of them showed pulmonary congestion. FEV1/FVC was abnormal in 3 patients. On the follow up scan, all patients with abnormal initial scan findings showed improved findings and they had improved clinical state. CONCLUSION: Inhalation/perfusion lung scans can detect inhalation burn injury noninvasively in early stage and may be useful in therapeutic decision making and follow up of patients.
Bronchoscopy
;
Burns, Inhalation
;
Decision Making
;
Estrogens, Conjugated (USP)
;
Female
;
Fires*
;
Follow-Up Studies
;
Humans
;
Inhalation*
;
Lung
;
Perfusion
;
Respiratory Function Tests
;
Thorax
;
Tuberculosis, Pulmonary

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