Diarrhoea is one of the causes of high morbidity and mortality rates in developing countries that have poor environmental sanitation, inadequate water supply, high poverty rates and low levels of education. The purpose of this study was to examine diarrhoea control models in toddlers of Banyuasin District wetlands. This study used a cross-sectional study design. The study was conducted in the wetland area of Banyuasin District with a sample of 296 respondents. Data analysis was performed in univariate, bivariate and multivariate. The results showed that there was a correlation between chemical indicators (p-value = 0.035), latrine sanitation (p-value = 0.004), latrine quality (p-value = 0.005), income (p-value = 0.023), and hand washing with soap (p-value = 0.035) with the occurrence of diarrhoea in toddlers of Banyuasin District wetlands area. 51.9% of diarrhoea prevention can be explained by the water factor (19.7%), sanitation factor (15.6%), personal hygiene factor (8.2%), toddler factor (4.8%) and mother factor (3.5%) in this study. Improvements of environmental sanitation related to healthy latrines, rubbish bins, sewerage and clean / drinking water sources, as well as intensive education about personal hygiene and breastfeeding toddlers can contribute in reducing the occurrence of diarrhoea in toddlers.

Objective To investigate clinically severe malaria patients with Plasmodium falciparum (P. falciparum), Plasmodium vivax (P. vivax) and mixed species infections. Methods This study was conducted at Dr. Saiful Anwar General Hospital, Malang, Indonesia, from December 2011 to May 2013. Twenty nine patients (mean age of 41 years, 22% female), who suffered from severe malaria according to World Health Organization criteria (major and minor) and other criteria based on previous studies, were selected by consecutive sampling. Blood samples were obtained at admission from peripheral blood for microscopic diagnostic, nested PCR and laboratory examination of blood chemistry. Laboratory results were compared between the groups and correlated to each other. Results From 29 samples, eight (28%) were diagnosed as P. falciparum mono-infection, 12 (41%) as P. vivax mono-infection and nine (31%) as mixed infections, confirmed by PCR. Cerebral malaria occurred in P. falciparum or mixed species infection only. Parasitaemia was highest in P. falciparum mono-infection. Mean haemoglobin was significantly lower in P. falciparum than P. vivax infection (P = 0.01). Mean thrombocyte count (77 138/μL) was low in all groups. Mean urea, creatinine, total and direct bilirubin were significantly higher in P. falciparum mono-infection compared to other groups, whereas aspartate aminotransferase and alanine aminotransferase showed no significant differences. Parasitaemia was positively correlated with an increase in urea, creatinine, bilirubin and leucocytosis in all species. Conclusions Both Plasmodium species can solely or in combination cause severe malaria. Mixed infection was generally more benign than P. falciparum mono-infection and seemed to have some protective effects.