1.A cavernous hemangioma located in the axillary area: Challenges in preoperative diagnosis and operation
Jihye CHOI ; Chan Sub PARK ; Joonseog KONG ; Hyun Ah KIM ; Woo Chul NOH ; Min Ki SEONG
Korean Journal of Clinical Oncology 2019;15(2):127-131
		                        		
		                        			
		                        			Cavernous hemangiomas are benign neoplasms of endothelial cells. Although this neoplasm has the potential to develop in all parts of the body, it rarely develops in the axilla; in fact, there are only two case reports of axillary cavernous hemangiomas in the literature. Here, we describe a third case, which occurred in a 30-year-old Korean woman. The patient presented with a palpable mass in the left axilla that was initially thought to be either a phyllodes tumor or a lymphoma based on imaging studies. However, the results of an excisional biopsy led to a diagnosis of cavernous hemangioma. Although uncommon, a cavernous hemangioma can be encountered unexpectedly, presenting as a mass in axilla. Although usually curative, surgery may be challenging not only because of the rarity of the condition, but also because of inconsistent preoperative findings and the involvement of large vessels.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Axilla
		                        			;
		                        		
		                        			Biopsy
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Endothelial Cells
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Hemangioma, Cavernous
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lymphoma
		                        			;
		                        		
		                        			Phyllodes Tumor
		                        			;
		                        		
		                        			Ultrasonography
		                        			;
		                        		
		                        			Vascular Neoplasms
		                        			
		                        		
		                        	
2.Huge Cavernous Hemangioma of the Chest Wall: A Rarely Arising Benign Tumor of Chest Wall.
In Hag SONG ; Seung Jin LEE ; Seock Yeol LEE ; Jinhun CHUNG
Soonchunhyang Medical Science 2018;24(2):223-227
		                        		
		                        			
		                        			A 35-year-old female complaining of a painful huge right posterior chest wall mass was admitted. Chest computed tomography showed the pleural invasion of mass and deformed ribs. Suspected diagnosis was hemangioma. Entire mass was removed carefully and pleural biopsy was performed. The operation was finished after bleeding control and chest tube insertion. The mass was diagnosed as a cavernous hemangioma histopathologically. Cavernous hemangioma of chest wall is a rare benign vascular tumor. Surgical operation of hemangioma demands meticulous bleeding control because of risk of hemorrhage.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Biopsy
		                        			;
		                        		
		                        			Chest Tubes
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Hemangioma
		                        			;
		                        		
		                        			Hemangioma, Cavernous*
		                        			;
		                        		
		                        			Hemorrhage
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Ribs
		                        			;
		                        		
		                        			Thoracic Wall*
		                        			;
		                        		
		                        			Thorax*
		                        			
		                        		
		                        	
3.A Thoracolumbar Pure Spinal Epidural Cavernous Hemangioma: A Case Report
Byeong Sam CHOI ; Ju Yeon KIM ; Sungjoon LEE
Journal of Korean Society of Spine Surgery 2018;25(4):169-174
		                        		
		                        			
		                        			STUDY DESIGN: Case report. OBJECTIVES: We report a case of pure epidural cavernous hemangioma located at the thoracolumbar spine in a 53-year-old woman that mimicked a neurogenic tumor on magnetic resonance imaging (MRI). SUMMARY OF LITERATURE REVIEW: A pure spinal epidural cavernous hemangioma without bony involvement is a very rare lesion about which limited information is available in the literature. MATERIALS AND METHODS: A 53-year-old woman visited our clinic for hypoesthesia with a tingling sensation in the left anterolateral thigh that had begun a month ago. No other neurologic symptoms or signs were present upon a neurologic examination. MRI from an outside hospital showed a 2.0×0.5 cm elongated mass at the T11-12 left neural foramen. The tumor was completely removed in piecemeal fashion. RESULTS: The histopathologic examination revealed a cavernous hemangioma, which was the final diagnosis. The outcome was favorable in that only operation-related mild back pain remained, without any neurologic deficits, after a postoperative follow-up of 2 years and 3 months. No recurrence was observed on MRI at 2 years postoperatively. CONCLUSION: Pure epidural spinal cavernous hemangioma is very rare, and it is very difficult to differentiate from other epidural lesions. However, we believe that it should be included in the differential diagnosis of spinal epidural tumors due to its favorable prognosis.
		                        		
		                        		
		                        		
		                        			Back Pain
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Epidural Neoplasms
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Hemangioma, Cavernous
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypesthesia
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Neurologic Examination
		                        			;
		                        		
		                        			Neurologic Manifestations
		                        			;
		                        		
		                        			Prognosis
		                        			;
		                        		
		                        			Recurrence
		                        			;
		                        		
		                        			Sensation
		                        			;
		                        		
		                        			Spine
		                        			;
		                        		
		                        			Thigh
		                        			;
		                        		
		                        			Thoracic Vertebrae
		                        			
		                        		
		                        	
5.Single Cavernous Hemangioma of the Small Bowel Diagnosed by Using Capsule Endoscopy in a Child with Chronic Iron-Deficiency Anemia.
Soo Jin BAE ; Geol HWANG ; Hyun Sik KANG ; Hyun Joo SONG ; Weon Young CHANG ; Young Hee MAENG ; Ki Soo KANG
Clinical Endoscopy 2015;48(4):340-344
		                        		
		                        			
		                        			Cavernous hemangiomas of the gastrointestinal tract are extremely rare. In particular, the diagnosis of small bowel hemangiomas is very difficult in children. A 13-year-old boy presented at the outpatient clinic with dizziness and fatigue. The patient was previously diagnosed with iron-deficiency anemia at 3 years of age and had been treated with iron supplements continuously and pure red cell transfusion intermittently. Laboratory tests indicated that the patient currently had iron-deficiency anemia. There was no evidence of gross bleeding, such as hematemesis or bloody stool. Laboratory findings indicated no bleeding tendency. Gastroduodenoscopy and colonoscopy results were negative. To obtain a definitive diagnosis, the patient underwent capsule endoscopy. A purplish stalked mass was found in the jejunum, and the mass was excised successfully. We report of a 13-year-old boy who presented with severe and recurrent iron-deficiency anemia caused by a cavernous hemangioma in the small bowel without symptoms of gastrointestinal bleeding.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Ambulatory Care Facilities
		                        			;
		                        		
		                        			Anemia, Iron-Deficiency*
		                        			;
		                        		
		                        			Capsule Endoscopy*
		                        			;
		                        		
		                        			Child*
		                        			;
		                        		
		                        			Colonoscopy
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Dizziness
		                        			;
		                        		
		                        			Fatigue
		                        			;
		                        		
		                        			Gastrointestinal Tract
		                        			;
		                        		
		                        			Hemangioma
		                        			;
		                        		
		                        			Hemangioma, Cavernous*
		                        			;
		                        		
		                        			Hematemesis
		                        			;
		                        		
		                        			Hemorrhage
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Iron
		                        			;
		                        		
		                        			Jejunum
		                        			;
		                        		
		                        			Male
		                        			
		                        		
		                        	
6.Pure spinal epidural cavernous hemangioma: report of one case.
Zhan HE ; Fang DING ; Jian-dong RONG ; Guang-yao ZHU
Journal of Zhejiang University. Medical sciences 2015;44(2):233-235
		                        		
		                        			
		                        			A 55-year-old man presented with progressive numbness and weakness of both lower limbs is reported. MRI demonstrated a pure epidural lesion at T3-6 space appearing as isointense on T1-weighted images with enhancement by contrast medium and hyperintense on T2-weighted images. The lesion was totally removed microsurgically. Histological examination revealed cavernous hemangioma. The patient made a good recovery after surgery.
		                        		
		                        		
		                        		
		                        			Epidural Space
		                        			;
		                        		
		                        			Hemangioma, Cavernous
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Spine
		                        			;
		                        		
		                        			pathology
		                        			
		                        		
		                        	
7.Unusual Presentation of Cerebral Cavernous Malformation.
Won Hyung KIM ; Dong Jun LIM ; Jong Il CHOI ; Sung Kon HA ; Sang Dae KIM ; Se Hoon KIM
Journal of Cerebrovascular and Endovascular Neurosurgery 2015;17(3):257-262
		                        		
		                        			
		                        			Cerebral cavernous malformations (CMs) are vascular malformations of the central nervous system, which can be detected in the absence of any clinical symptoms. Nodules and cysts with mixed signal intensity and a peripheral hemosiderin rim are considered brain magnetic resonance imaging (MRI) findings typical of CMs. A 48-year-old man was admitted to our hospital because of abnormal MRI findings without significant neurological symptoms. A cyst with an internal fluid-fluid level was found in the left basal ganglia on the initial brain MRI. We decided to observe the natural course of the asymptomatic lesion with serial MRI follow-up. On MRI at the 5-month follow-up, the cystic mass was enlarged and showed findings consistent with those of cystic CM. Surgical resection was performed and the pathological diagnosis was CM. Our experience suggests that the initial presentation of a CM can be a pure cyst and neurosurgeons should consider the likelihood of CMs in cases of cystic cerebral lesions with intracystic hemorrhage.
		                        		
		                        		
		                        		
		                        			Basal Ganglia
		                        			;
		                        		
		                        			Brain
		                        			;
		                        		
		                        			Central Nervous System
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Hemangioma, Cavernous, Central Nervous System*
		                        			;
		                        		
		                        			Hemorrhage
		                        			;
		                        		
		                        			Hemosiderin
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Vascular Malformations
		                        			
		                        		
		                        	
8.Thoracic Extradural Cavernous Hemangioma Mimicking a Dumbbell-Shaped Tumor.
Won Joo JEONG ; Il CHOI ; Han Yu SEONG ; Sung Woo ROH
Journal of Korean Neurosurgical Society 2015;58(1):72-75
		                        		
		                        			
		                        			Dumbbell-shaped spinal extradural cavernous hemangioma is rare. The differential diagnosis of dumbbell-shaped spinal tumors based on magnetic resonance imaging includes schwannoma and lymphoma. Here, we report a dumbbell-shaped spinal extradural cavernous hemangioma with intrathoracic growth on T2-3 in a 64-year-old man complaining of right side infrascapular area back pain with no neurologic deficit. The cavernous hemangioma was resected through combined video-assisted thoracoscopy and laminectomy without a fusion procedure. The patient had tolerable operative wound pain with no neurologic deficit after surgery. Based on magnetic resonance imaging findings and a review of the literature, we discuss cavernous hemangioma among the differential diagnosis of paravertebral dumbbell-shaped spinal tumors and the importance of complete resection.
		                        		
		                        		
		                        		
		                        			Back Pain
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Hemangioma
		                        			;
		                        		
		                        			Hemangioma, Cavernous*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laminectomy
		                        			;
		                        		
		                        			Lymphoma
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Neurilemmoma
		                        			;
		                        		
		                        			Neurologic Manifestations
		                        			;
		                        		
		                        			Spine
		                        			;
		                        		
		                        			Thoracoscopy
		                        			;
		                        		
		                        			Wounds and Injuries
		                        			
		                        		
		                        	
9.Computed Tomography and Magnetic Resonance Imaging Findings of Nasal Cavity Hemangiomas According to Histological Type.
Jun Ho KIM ; Sun Won PARK ; Soo Chin KIM ; Myung Kwan LIM ; Tae Young JANG ; Yeo Ju KIM ; Young Hye KANG ; Ha Young LEE
Korean Journal of Radiology 2015;16(3):566-574
		                        		
		                        			
		                        			OBJECTIVE: To compare computed tomography (CT) and magnetic resonance imaging (MRI) findings between two histological types of nasal hemangiomas (cavernous hemangioma and capillary or lobular capillary hemangioma). MATERIALS AND METHODS: CT (n = 20; six pre-contrast; 20 post-enhancement) and MRI (n = 7) images from 23 patients (16 men and seven women; mean age, 43 years; range, 13-73 years) with a pathologically diagnosed nasal cavity hemangioma (17 capillary and lobular capillary hemangiomas and six cavernous hemangiomas) were reviewed, focusing on lesion location, size, origin, contour, enhancement pattern, attenuation or signal intensity (SI), and bony changes. RESULTS: The 17 capillary and lobular hemangiomas averaged 13 mm (range, 4-37 mm) in size, and most (n = 13) were round. Fourteen capillary hemangiomas had marked or moderate early phase enhancement on CT, which dissipated during the delayed phase. Four capillary hemangiomas on MRI showed marked enhancement. Bony changes were usually not seen on CT or MRI (seen on five cases, 29.4%). Half of the lesions (2/4) had low SI on T1-weighted MRI images and heterogeneously high SI with signal voids on T2-weighted images. The six cavernous hemangiomas were larger than the capillary type (mean, 20.5 mm; range, 10-39 mm) and most had lobulating contours (n = 4), with characteristic enhancement patterns (three centripetal and three multifocal nodular), bony remodeling (n = 4, 66.7%), and mild to moderate heterogeneous enhancement during the early and delayed phases. CONCLUSION: CT and MRI findings are different between the two histological types of nasal hemangiomas, particularly in the enhancement pattern and size, which can assist in preoperative diagnosis and planning of surgical tumor excision.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Hemangioma, Capillary/*radiography
		                        			;
		                        		
		                        			Hemangioma, Cavernous/diagnosis/*radiography
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			*Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Nasal Cavity/radiography
		                        			;
		                        		
		                        			Paranasal Sinuses/*radiography
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			*Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
10.Clinical Study of the Intranasal Hemangioma.
Dong Sik CHANG ; Myoung Su CHOI ; Ho Yun LEE ; Chin Saeng CHO ; Seung Gu PARK ; No Seon PARK ; Ji Chan KIM ; Hyun Jin SON ; Seung Yun LEE ; Ah Young KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 2015;58(5):324-329
		                        		
		                        			
		                        			BACKGROUND AND OBJECTIVES: Hemangioma of the nasal cavity is an uncommon benign vascular tumor. This study aimed to analyze the clinical manifestations, radiologic findings, treatment modalities, and outcomes of intranasal hemangiomas. SUBJECTS AND METHOD: Retrospective reviews of the medical record were performed on 13 patients, who were treated for intranasal hemangioma from 2005 to 2014. RESULTS: Of the 13 patients identified, there were seven males and six females ranging from 11 to 80 years of age (mean age of 48.1+/-21.5). Epistaxis was the most common presenting symptom. Most common site of origin was the inferior turbinate. CT scans showed variable enhancement of the nasal mass without bony erosion. Preoperative diagnosis accuracy rate was 76.9%. The tumor was histopathologically classified as follows: capillary hemangioma (n=6, 46.1%), cavernous hemangioma (n=3, 23.1%), venous hemangioma (n=2, 15.4%), and mixed hemangioma (n=2, 15.4%). Endoscopic excisional surgery (n=11, 94.6%) and local excision (n=2, 15.4%) were performed for complete removal of the hemangioma. Preoperative selective embolization was performed on one patient. No evidence of recurrence after the surgery was observed. CONCLUSION: Intranasal hemangioma was usually found to occur in the inferior turbinate and the most common symptom was epistaxis. Capillary hemangioma was the most common type. Complete excision was recommended to prevent recurrence.
		                        		
		                        		
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Epistaxis
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Hemangioma*
		                        			;
		                        		
		                        			Hemangioma, Capillary
		                        			;
		                        		
		                        			Hemangioma, Cavernous
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Medical Records
		                        			;
		                        		
		                        			Nasal Cavity
		                        			;
		                        		
		                        			Recurrence
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Turbinates
		                        			
		                        		
		                        	
            
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