2.Adverse Cardiovascular Events after a Venomous Snakebite in Korea.
Oh Hyun KIM ; Joon Woo LEE ; Hyung Il KIM ; Kyoungchul CHA ; Hyun KIM ; Kang Hyun LEE ; Sung Oh HWANG ; Yong Sung CHA
Yonsei Medical Journal 2016;57(2):512-517
PURPOSE: Although cardiac involvement is an infrequently recognized manifestation of venomous snakebites, little is known of the adverse cardiovascular events (ACVEs) arising as a result of snakebite in Korea. Accordingly, we studied the prevalence of ACVEs associated with venomous snakebites in Korea and compared the clinical features of patients with and without ACVEs. MATERIALS AND METHODS: A retrospective review was conducted on 65 consecutive venomous snakebite cases diagnosed and treated at the emergency department of Wonju Severance Christian Hospital between May 2011 and October 2014. ACVEs were defined as the occurrence of at least one of the following: 1) myocardial injury, 2) shock, 3) ventricular dysrhythmia, or 4) cardiac arrest. RESULTS: Nine (13.8%) of the 65 patients had ACVEs; myocardial injury (9 patients, 13.8%) included high sensitivity troponin I (hs-TnI) elevation (7 patients, 10.8%) or electrocardiogram (ECG) determined ischemic change (2 patients, 3.1%), and shock (2 patient, 3.1%). Neither ventricular dysrhythmia nor cardiac arrest was observed. The median of elevated hs-TnI levels observed in the present study were 0.063 ng/mL (maximum: 3.000 ng/mL) and there was no mortality in the ACVEs group. Underlying cardiac diseases were more common in the ACVEs group than in the non-ACVEs group (p=0.017). Regarding complications during hospitalization, 3 patients (5.4%) in the non-ACVEs group and 3 patients (33.3%) in the ACVEs group developed bleeding (p=0.031). CONCLUSION: Significant proportion of the patients with venomous snakebite is associated with occurrence of ACVEs. Patients with ACVEs had more underlying cardiac disease and bleeding complication.
Aged
;
Arrhythmias, Cardiac/epidemiology/*etiology
;
Cardiovascular Diseases/epidemiology
;
Electrocardiography
;
Emergency Service, Hospital
;
Female
;
Heart Arrest/epidemiology/*etiology
;
Hospitalization
;
Humans
;
Male
;
Middle Aged
;
Prevalence
;
Republic of Korea
;
Retrospective Studies
;
Snake Bites/*complications/diagnosis/epidemiology
;
Troponin I/blood
3.A 40-Year-Old Man with Rashes and Palpitations.
Shan Xian LEE ; Yong Kwang TAY
Annals of the Academy of Medicine, Singapore 2016;45(6):264-266
Adult
;
Cardiomyopathies
;
diagnosis
;
etiology
;
Electrocardiography
;
Heart Block
;
diagnosis
;
etiology
;
Humans
;
Male
;
Sarcoidosis
;
complications
;
diagnosis
;
pathology
;
Skin Diseases
;
diagnosis
;
etiology
;
pathology
4.Fever in a Patient with a Previous Gastrectomy.
Debra Gf SEOW ; Po Fun CHAN ; Boon Lock CHIA ; Joshua Py LOH
Annals of the Academy of Medicine, Singapore 2016;45(3):117-120
Adenocarcinoma
;
surgery
;
Candidiasis
;
etiology
;
Cardiac Tamponade
;
diagnosis
;
etiology
;
Echocardiography
;
Electrocardiography
;
Esophageal Fistula
;
complications
;
diagnostic imaging
;
Fever
;
etiology
;
Gastrectomy
;
Haemophilus Infections
;
etiology
;
Heart Diseases
;
complications
;
diagnostic imaging
;
Humans
;
Male
;
Middle Aged
;
Pericardial Effusion
;
diagnostic imaging
;
etiology
;
Pericarditis
;
diagnostic imaging
;
etiology
;
Postoperative Complications
;
diagnostic imaging
;
Staphylococcal Infections
;
etiology
;
Stomach Neoplasms
;
surgery
;
Streptococcal Infections
;
etiology
;
Tomography, X-Ray Computed
5.Recent Advances in Kawasaki Disease.
Yonsei Medical Journal 2016;57(1):15-21
Kawasaki disease (KD) is characterized with acute systemic vasculitis, occurs predominantly in children between 6 months to 5 years of age. Patients with this disease recover well and the disease is self-limited in most cases. Since it can lead to devastating cardiovascular complications, KD needs special attention. Recent reports show steady increases in the prevalence of KD in both Japan and Korea. However, specific pathogens have yet to be found. Recent advances in research on KD include searches for genetic susceptibility related to KD and research on immunopathogenesis based on innate and acquired immunity. Also, search for etiopathogenesis and treatment of KD has been actively sought after using animal models. In this paper, the recent progress of research on KD was discussed.
*Genetic Predisposition to Disease
;
Heart Diseases/*complications
;
Humans
;
Mucocutaneous Lymph Node Syndrome/*diagnosis/etiology/physiopathology/therapy
6.A case of left atria subendocardial thrombus with sick sinus syndrome.
Journal of Central South University(Medical Sciences) 2016;41(9):1005-1008
The clinical data for a patient with sick sinus syndrome was retrospectively analyzed. The patient was treated because of his heart palpitations and the increased chest pain. The patient admitted to the hospital under consideration for the left atrial tumor dependent on the echocardiography findings. After the CT scan and the dynamic ECG examination, the patient successfully underwent the left atrial tumor resection, atrial septal repair and cardiac pacing lead installation. The postoperative pathological diagnosis showed that the infective endocarditis and left atrial thrombus in left atrium was cured. The patient was discharged after postoperative anti-inflammatory therapy. By analyzing the reasons for misdignosis before or during surgery, the possible mechanisms for left atrial subendocardial thrombus have been found. This study suggests that it is necessary to combine imaging diagnosis and clinical observations to distinguish tumor from excrescence.
Anti-Inflammatory Agents
;
therapeutic use
;
Arrhythmias, Cardiac
;
etiology
;
surgery
;
Atrial Septum
;
surgery
;
Computed Tomography Angiography
;
Diagnosis, Differential
;
Diagnostic Errors
;
Echocardiography
;
Endocarditis
;
diagnosis
;
therapy
;
Heart Atria
;
diagnostic imaging
;
surgery
;
Heart Diseases
;
etiology
;
surgery
;
Heart Neoplasms
;
complications
;
diagnostic imaging
;
surgery
;
Humans
;
Male
;
Pacemaker, Artificial
;
Retrospective Studies
;
Sick Sinus Syndrome
;
etiology
;
surgery
;
Thrombosis
;
etiology
;
surgery
7.Associations Between the Continuity of Ambulatory Care of Adult Diabetes Patients in Korea and the Incidence of Macrovascular Complications.
Young Hoon GONG ; Seok Jun YOON ; Hyeyoung SEO ; Dongwoo KIM
Journal of Preventive Medicine and Public Health 2015;48(4):188-194
OBJECTIVES: The goal of this study was to identify association between the continuity of ambulatory care of diabetes patients in South Korea (hereafter Korea) and the incidence of macrovascular complications of diabetes, using claims data compiled by the National Health Insurance Services of Korea. METHODS: This study was conducted retrospectively. The subjects of the study were 43 002 patients diagnosed with diabetes in 2007, who were over 30 years of age, and had insurance claim data from 2008. The macrovascular complications of diabetes mellitus were limited to ischemic heart disease and ischemic stroke. We compared the characteristics of the patients in whom macrovascular complications occurred from 2009 to 2012 to the characteristics of the patients who had no such complications. Multiple logistic regression was used to assess the effects of continuity of ambulatory care on diabetic macrovascular complications. The continuity of ambulatory diabetes care was estimated by metrics such as the medication possession ratio, the quarterly continuity of care and the number of clinics that were visited. RESULTS: Patients with macrovascular complications showed statistically significant differences regarding sex, age, comorbidities, hypertension, dyslipidemia and continuity of ambulatory diabetes care. Visiting a lower number of clinics reduced the odds ratio for macrovascular complications of diabetes. A medication possession ratio below 80% was associated with an increased odds ratio for macrovascular complications, but this result was of borderline statistical significance. CONCLUSIONS: Diabetes care by regular health care providers was found to be associated with a lower occurrence of diabetic macrovascular complications. This result has policy implications for the Korean health care system, in which the delivery system does not work properly.
Adult
;
Aged
;
Aged, 80 and over
;
*Ambulatory Care
;
Diabetes Complications
;
Diabetes Mellitus/*diagnosis
;
Dyslipidemias/complications
;
Female
;
Heart Diseases/*epidemiology/etiology
;
Humans
;
Hypertension/complications
;
Incidence
;
Insurance Claim Reporting
;
Logistic Models
;
Male
;
Middle Aged
;
Odds Ratio
;
Republic of Korea/epidemiology
;
Retrospective Studies
;
Risk Factors
;
Stroke/*epidemiology/etiology
8.Acute myocardial infarction caused by a floating thrombus in the proximal ascending aorta.
Woong JEON ; Seung Jin LEE ; Sang Ho PARK ; Se Whan LEE ; Won Yong SHIN ; Dong Kyu JIN
The Korean Journal of Internal Medicine 2015;30(6):921-924
No abstract available.
*Aorta, Thoracic/ultrasonography
;
Aortic Diseases/*complications/diagnosis
;
Catheterization, Peripheral/*adverse effects
;
Cerebral Angiography/*adverse effects
;
Electrocardiography
;
Fatal Outcome
;
*Femoral Artery
;
Heart Arrest/diagnosis/etiology
;
Humans
;
Male
;
Middle Aged
;
Myocardial Infarction/diagnosis/*etiology
;
Punctures
;
*Sinus of Valsalva/ultrasonography
;
Thrombosis/diagnosis/*etiology
9.Cardiovascular Events of Electrical Cardioversion Under Optimal Anticoagulation in Atrial Fibrillation: The Multicenter Analysis.
Dong Geum SHIN ; Iksung CHO ; Briain O HARTAIGH ; Hee Sun MUN ; Hye Young LEE ; Eui Seock HWANG ; Jin Kyu PARK ; Jae Sun UHM ; Hui Nam PAK ; Moon Hyoung LEE ; Boyoung JOUNG
Yonsei Medical Journal 2015;56(6):1552-1558
PURPOSE: Electric cardioversion has been successfully used in terminating symptomatic atrial fibrillation (AF). Nevertheless, largescale study about the acute cardiovascular events following electrical cardioversion of AF is lacking. This study was performed to evaluate the incidence, risk factors, and clinical consequences of acute cardiovascular events following electrical cardioversion of AF. MATERIALS AND METHODS: The study enrolled 1100 AF patients (mean age 60+/-11 years) who received cardioversion at four tertiary hospitals. Hospitalizations for stroke/transient ischemic attack, major bleedings, and arrhythmic events during 30 days post electric cardioversion were assessed. RESULTS: The mean duration of anticoagulation before cardioversion was 95.8+/-51.6 days. The mean International Normalized Ratio at the time of cardioversion was 2.4+/-0.9. The antiarrhythmic drugs at the time of cardioversion were class I (45%), amiodarone (40%), beta-blocker (53%), calcium-channel blocker (21%), and other medication (11%). The success rate of terminating AF via cardioversion was 87% (n=947). Following cardioversion, 5 strokes and 5 major bleedings occurred. The history of stroke/transient ischemic attack (OR 6.23, 95% CI 1.69-22.90) and heart failure (OR 6.40, 95% CI 1.77-23.14) were among predictors of thromboembolic or bleeding events. Eight patients were hospitalized for bradyarrhythmia. These patients were more likely to have had a lower heart rate prior to the procedure (p=0.045). Consequently, 3 of these patients were implanted with a permanent pacemaker. CONCLUSION: Cardioversion appears as a safe procedure with a reasonably acceptable cardiovascular event rate. However, to prevent the cardiovascular events, several risk factors should be considered before cardioversion.
Aged
;
Amiodarone/therapeutic use
;
Anti-Arrhythmia Agents/therapeutic use
;
Atrial Fibrillation/*complications/epidemiology/*therapy
;
Bradycardia/epidemiology/etiology
;
Cardiovascular Diseases/epidemiology/*etiology
;
Electric Countershock/*methods
;
Female
;
Heart Failure/epidemiology/etiology
;
Humans
;
Incidence
;
Male
;
Middle Aged
;
Risk Factors
;
Stroke/diagnosis/epidemiology/*etiology
;
Treatment Outcome
10.A case of repeated unconsciousness caused by excrescence locking bicuspid aortic valve.
Zijian XIE ; Xiaogang LI ; Mingyuan LIN ; Ruixia HUANG ; Weihong JIANG
Journal of Central South University(Medical Sciences) 2015;40(12):1404-1406
We received a patient who repeated unconsciousness due to excrescence locking bicuspid aortic valve. He experienced unconsciousness and treatments with anti infection, surgical operation, valve replacement and recovery. It was a rare case, which made us realize that the heart color Doppler ultrasound should be regularly performed in patients with aortic valve abnormalities. Once patients were found to have infective endocarditis combined with the valve vegetations, they should be formally treated as soon as possible.
Aortic Valve
;
abnormalities
;
physiopathology
;
Echocardiography, Doppler, Color
;
Endocarditis, Bacterial
;
diagnosis
;
Heart Valve Diseases
;
physiopathology
;
Humans
;
Male
;
Unconsciousness
;
etiology

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