1.Revised Electroencephalography Terminology and Clinical Consideration
Hong Jin KIM ; Sang Yeon KIM ; Hyun Goo KANG ; Han Uk RYU
Journal of the Korean Neurological Association 2022;40(2):99-120
Electroencephalography (EEG) has been used for decades to evaluate and assess brain function. It is a useful method to diagnose brain disorders. However, confirmed interpretation of EEG is quite challenging because there is no standardized method for EEG reading and this may lead to interrater variability even among expert electroencephalographers. In this background, uniformly accepted nomenclature for EEG pattern were required to improve interrater agreement and to support communication for EEG research. American Clinical Neurophysiology Society (ACNS) established the standardized critical care EEG terminology since 2012 and has recently published the revised 2021 version of EEG terminology. This review covers new concepts of 2021 ACNS EEG terminology and clinical considerations of various EEG patterns.
2.Lower High-Density Lipoprotein Cholesterol Concentration Is Independently Associated with Greater Future Accumulation of Intra-Abdominal Fat
Sun Ok SONG ; You-Cheol HWANG ; Han Uk RYU ; Steven E. KAHN ; Donna L. LEONETTI ; Wilfred Y. FUJIMOTO ; Edward J. BOYKO
Endocrinology and Metabolism 2021;36(4):835-844
Background:
Both intra-abdominal fat (IAF) and high-density lipoprotein cholesterol (HDL-C) are known to be associated with cardiometabolic health. We evaluated whether the accumulation of computed tomography (CT)-measured IAF over 5 years was related to baseline HDL-C concentration in a prospective cohort study.
Methods:
All participants were Japanese-Americans between the ages of 34 and 74 years. Plasma HDL-C concentration and CT measurements of IAF, abdominal subcutaneous fat (SCF), and thigh SCF cross-sectional areas were assessed at baseline and at 5-year follow-up visits.
Results:
A total of 397 subjects without diabetes were included. The mean±standard deviation HDL-C concentration was 51.6±13.0 mg/dL in men and 66.0±17.0 mg/dL in women, and the IAF was 91.9±48.4 cm2 in men and 63.1±39.5 cm2 in women. The baseline plasma concentration of HDL-C was inversely associated with the change in IAF over 5 years using multivariable regression analysis with adjustment for age, sex, family history of diabetes, weight change over 5 years, and baseline measurements of body mass index, IAF, abdominal SCF, abdominal circumference, thigh SCF, and homeostatic model assessment for insulin resistance.
Conclusion
These results demonstrate that HDL-C concentration significantly predicts future accumulation of IAF over 5 years independent of age, sex, insulin sensitivity, and body composition in Japanese-American men and women without diabetes.
3.Lower High-Density Lipoprotein Cholesterol Concentration Is Independently Associated with Greater Future Accumulation of Intra-Abdominal Fat
Sun Ok SONG ; You-Cheol HWANG ; Han Uk RYU ; Steven E. KAHN ; Donna L. LEONETTI ; Wilfred Y. FUJIMOTO ; Edward J. BOYKO
Endocrinology and Metabolism 2021;36(4):835-844
Background:
Both intra-abdominal fat (IAF) and high-density lipoprotein cholesterol (HDL-C) are known to be associated with cardiometabolic health. We evaluated whether the accumulation of computed tomography (CT)-measured IAF over 5 years was related to baseline HDL-C concentration in a prospective cohort study.
Methods:
All participants were Japanese-Americans between the ages of 34 and 74 years. Plasma HDL-C concentration and CT measurements of IAF, abdominal subcutaneous fat (SCF), and thigh SCF cross-sectional areas were assessed at baseline and at 5-year follow-up visits.
Results:
A total of 397 subjects without diabetes were included. The mean±standard deviation HDL-C concentration was 51.6±13.0 mg/dL in men and 66.0±17.0 mg/dL in women, and the IAF was 91.9±48.4 cm2 in men and 63.1±39.5 cm2 in women. The baseline plasma concentration of HDL-C was inversely associated with the change in IAF over 5 years using multivariable regression analysis with adjustment for age, sex, family history of diabetes, weight change over 5 years, and baseline measurements of body mass index, IAF, abdominal SCF, abdominal circumference, thigh SCF, and homeostatic model assessment for insulin resistance.
Conclusion
These results demonstrate that HDL-C concentration significantly predicts future accumulation of IAF over 5 years independent of age, sex, insulin sensitivity, and body composition in Japanese-American men and women without diabetes.
4.Bariatric surgery versus medical therapy in Korean obese patients: prospective multicenter nonrandomized controlled trial (KOBESS trial)
Do Joong PARK ; Sena AN ; Young Suk PARK ; Joo-Ho LEE ; Hyuk-Joon LEE ; Tae Kyung HA ; Yong-Jin KIM ; Seung-Wan RYU ; Sang-Moon HAN ; Moon-Won YOO ; Sungsoo PARK ; Sang-Uk HAN ; Jae-Heon KANG ; Jin-Won KWON ; Yoonseok HEO
Annals of Surgical Treatment and Research 2021;101(4):197-205
Purpose:
The aim of this study was to show that bariatric surgery (BS) is more effective than medical therapy (MT) in Asian obese patients.
Methods:
In this prospective, multicenter, nonrandomized, controlled trial, obese patients with body mass index of ≥35 kg/m2 or 30.0–34.9 kg/m2 with obesity-related comorbidities were assigned to undergo BS, such as laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass, or MT. Patients who underwent BS were evaluated 4, 12, 24, and 48 weeks after surgery, whereas patients who received MT were monitored at a hospital every 6 weeks for 1 year. At each visit, weight, waist and hip circumference, and blood pressure were measured, and patients underwent physical examination and laboratory testing. Health-related quality of life (HQOL) was investigated using Euro QOL-5 Dimension, Impact of Weight on Quality of Life questionnaire-Lite and Obesity-related Problems scale.
Results:
The study included 264 patients from 13 institutions; of these, 64 underwent BS and 200 received MT. Of the patients who underwent BS, 6.3% experienced early complications. Relative weight changes from baseline to 48 weeks were significantly greater in the BS than in the MT group (26.9% vs. 2.1%, P < 0.001), as were the rates of remission of diabetes (47.8% vs. 16.7%, P = 0.014), hypertension (60.0% vs. 26.1%, P < 0.001), and dyslipidemia (63.2% vs. 22.0%, P < 0.001). HQOL was better in the BS than in the MT group at 48 weeks.
Conclusion
BS was safe and effective in Korean obese patients, with greater weight reduction, remission of comorbidities, and quality of life improvement than MT.
5.Two Focal Seizure in a Patient Caused by Different Mechanism
Hong-Jin KIM ; Han Uk RYU ; Byoung-Soo SHIN ; Hyun Goo KANG
Journal of the Korean Neurological Association 2021;39(4):322-326
Poststroke epilepsy is the most common cause of epilepsy in adult. Acute symptomatic seizure is a provoked seizure usually caused by systemic metabolic disorders. If stroke patient has a seizure, it is very important to discriminate whether it is a poststroke epilepsy or provoked seizure. The reason is that there are differences in the approach to treatment and the continuation of antiepileptic drugs. We report a stroke mimic patient who had two different mechanisms of focal seizures.
6.The pattern of postoperative quality of life following minimally invasive gastrectomy for gastric cancer: a prospective cohort from Korean multicenter robotic gastrectomy trial
Jong-Ho CHOI ; Sang-Uk HAN ; Han-Kwang YANG ; Young-Woo KIM ; Keun Won RYU ; Joong-Min PARK ; Ji Yeong AN ; Min-Chan KIM ; Sungsoo PARK ; Kyo Young SONG ; Sung Jin OH ; Seong-Ho KONG ; Byoung Jo SUH ; Dae Hyun YANG ; Tae Kyung HA ; Hyoung-Il KIM ; Woo Jin HYUNG ; Hyuk-Joon LEE
Annals of Surgical Treatment and Research 2020;99(5):275-284
Purpose:
Quality of life (QOL) has become important in the trend of emphasizing patient satisfaction. This study aimed to evaluate the QOL in patients who underwent laparoscopic or robotic gastrectomy for gastric cancer.
Methods:
A prospective trial was performed involving patients who underwent laparoscopic or robotic gastrectomy for primary gastric cancer at 11 hospitals in Korea. Within this comparative trial, QOL, postoperative pain, and long-term complications were exanimated. The quality-of-life questionnaire (QLQ)-C30 and QLQ-STO22 developed by the European Organization for Research and Treatment of Cancer were used for the QOL survey. We compared the data after dividing it into several types of characteristics as follows; device (robotic or laparoscopic), operation type, pathological stage, and sex.Biased components were extracted by logistic regression analysis. Propensity score matching was applied to the data set with the biased components.
Results:
In total, 434 patients (211 for laparoscopic surgery and 223 for robotic surgery) were enrolled, out of which 321 patients who responded to both preoperative and postoperative surveys were selected for analysis. Robotic gastrectomy was not different from laparoscopic gastrectomy with respect to postoperative QOL. Distal gastrectomy showed better scores than total gastrectomy in terms of role functioning, social functioning, fatigue, nausea/vomiting, pain, dyspnea, constipation, financial difficulties, dysphagia, eating restrictions, anxiety, taste, and body image. Male patients showed better scores on the 19 scales compared to female patients.
Conclusion
Robotic and laparoscopic approaches for gastric cancer surgery did not differ from each other with respect to QOL. Distal gastrectomy resulted in better QOL than total gastrectomy.
7.Safety of Laparoscopic Sentinel Basin Dissection in Patients with Gastric Cancer: an Analysis from the SENORITA Prospective Multicenter Quality Control Trial.
Ji Yeong AN ; Jae Seok MIN ; Young Joon LEE ; Sang Ho JEONG ; Hoon HUR ; Sang Uk HAN ; Woo Jin HYUNG ; Gyu Seok CHO ; Gui Ae JEONG ; Oh JEONG ; Young Kyu PARK ; Mi Ran JUNG ; Ji Yeon PARK ; Young Woo KIM ; Hong Man YOON ; Bang Wool EOM ; Keun Won RYU
Journal of Gastric Cancer 2018;18(1):30-36
PURPOSE: We investigated complications after laparoscopic sentinel basin dissection (SBD) for patients with gastric cancer who were enrolled in a quality control study, prior to the phase III trial of sentinel lymph node navigation surgery (SNNS). MATERIALS AND METHODS: We analyzed prospective data from a Korean multicenter prerequisite quality control trial of laparoscopic SBD for gastric cancer and assessed procedure-related and surgical complications. All complications were classified according to the Clavien-Dindo Classification (CDC) system and were compared with the results of the previously published SNNS trial. RESULTS: Among the 108 eligible patients who were enrolled in the quality control trial, 8 (7.4%) experienced complications during the early postoperative period. One patient with gastric resection-related duodenal stump leakage recovered after percutaneous drainage (grade IIIa in CDC). The other postoperative complications were mild and patients recovered with supportive care. No complications were directly related to the laparoscopic SBD procedure or tracer usage, and there were no mortalities. The laparoscopic SBD complication rates and patterns that were observed in this study were comparable to those of a previously reported trial. CONCLUSIONS: The results of our prospective, multicenter quality control trial demonstrate that laparoscopic SBD is a safe procedure during SNNS for gastric cancer.
Classification
;
Drainage
;
Humans
;
Lymph Nodes
;
Mortality
;
Postoperative Complications
;
Postoperative Period
;
Prospective Studies*
;
Quality Control*
;
Sentinel Lymph Node Biopsy
;
Stomach Neoplasms*
8.Parasomnia as an Initial Presentation of Narcolepsy
Jin Ju KANG ; Hyun Goo KANG ; Man Wook SEO ; Byoung Soo SHIN ; Sun Young OH ; Han Uk RYU
Journal of Sleep Medicine 2018;15(1):27-30
Narcolepsy is characterized by excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucinations. Only a few studies have focused on non-rapid eye movement (NREM) and REM parasomnias in narcolepsy. We report a narcolepsy without cataplexy patient presenting parasomnia as an initial symptom. A 18-year-old boy was admitted to hospital for abnormal behavior of sitting up during sleep over 2 years. He had a symptom of lethargy without cataplexy and subjective excessive daytime sleepiness, but his family found him often asleep during daytime. He underwent 3 times of polysomnography (PSG) including 1 multiple sleep latency test (MSLT) after the last PSG. The last PSG showed 1 episode of abrupt sitting. Three sleep REM onset period was observed in MSLT which was not detect in PSG. Parasomnia as an initial symptom of narcolepsy is a rare clinical entity. The MSLT may be useful in the evaluation of patients with parasomnia and unexplained hypersomnia.
Adolescent
;
Cataplexy
;
Disorders of Excessive Somnolence
;
Eye Movements
;
Hallucinations
;
Humans
;
Lethargy
;
Male
;
Narcolepsy
;
Parasomnias
;
Polysomnography
;
Sleep Arousal Disorders
;
Sleep Paralysis
9.Epilepsy and Driving Regulation in Korea
Hyun Goo KANG ; Sang Duk LEE ; Sang Ahm LEE ; Seung Ho JEON ; Man Wook SEO ; Byoung Soo SHIN ; Sun Young OH ; Han Uk RYU
Journal of the Korean Neurological Association 2018;36(2):65-73
In Korea, current status of epilepsy and driving are challenging and there are lack of formal legal guidelines about driving in patients with epilepsy. According to the default standards in Korean Road Traffic law, patients with epilepsy are restricted or prohibited from driving except who are conditionally allowed to drive by the Aptitude Judgement Committee (AJC). Though the AJC consist of medical doctors and traffic officials, new regulation and guidelines are required for various type of seizure and characteristics of patients with epilepsy. This review outlines the current applicable legislation about epilepsy and driving in Korea as well as that of the overseas country calling for new laws to establish a consistent assessment.
Accidents, Traffic
;
Aptitude
;
Automobile Driving
;
Epilepsy
;
Humans
;
Jurisprudence
;
Korea
;
Seizures
10.Cerebral Heterotopia Presenting as Epilepsy with Auditory Aura
Sang Mi NOH ; Han Uk RYU ; Hyun Goo KANG
Journal of the Korean Neurological Association 2018;36(4):411-412
No abstract available.
Epilepsy

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