1.Cohort study profile: a cohort of Korean atomic bomb survivors and their offspring
Hamin LEE ; Jin-Wu NAM ; Mi Kyung KIM ; Inah KIM ; Yu-Mi KIM ; Boyoung PARK
Epidemiology and Health 2024;46(1):e2024089-
The Korean Atomic Bomb Survivor Cohort (K-ABC) study was designed to investigate the health impacts of atomic bomb exposure on Korean survivors and to explore whether these effects are passed down genetically to their descendants. This paper outlines the study’s design, data collection methods, baseline socio-demographic characteristics, exposure status, and disease prevalence among the participants, based on survey responses and health examinations. From 2020 to 2024, a total of 2,544 individuals, comprising 1,109 atomic bomb survivors (G1), 1,193 children of G1 (G2), and 242 grandchildren of G1 (G3), consented to participate in the study. Of these, 1,828 participants (659 in G1, 927 in G2, and 242 in G3) completed the survey and underwent health examinations, representing a participation rate of 71.9%. Exposure information was gathered using a questionnaire and verified through records from the Korean Red Cross and a handbook issued by the Japanese government. Disease prevalence was determined based on participants’ self-reported physician diagnoses. This study presents details about the K-ABC study and provides baseline data on the participants recruited. These data will be valuable for interpreting the results of future K-ABC studies.
2.Effects of Information and Communication Technology Use on the Executive Function of Older Adults without Dementia: A Longitudinal Fixed-Effect Analysis
Hamin LEE ; Sangmi PARK ; Seungho HAN ; Hyeon Dong LEE ; Ickpyo HONG ; Hae Yean PARK
Annals of Geriatric Medicine and Research 2024;28(4):445-452
Background:
Impaired executive function is common in older adults. This study examined the causal relationship between the use of information and communication technology (ICT) and executive function in older adults over time.Method: This study performed a secondary analysis of data from four waves (2016–2019) of the National Health and Aging Trends Study. A fixed-effect analysis was conducted to examine the effects of ICT on the executive function of older adults without dementia aged ≥65 years. This study analyzed data from 3,334 respondents.
Results:
We observed significant positive effects of ICT use on executive function over time (standardized β=0.043–0.045; 95% confidence interval, 0.001–0.043; p<0.05).
Conclusion
The current findings support the use of ICT as a protective approach to prevent decline in executive function in community-dwelling older adults.
3.Cohort study profile: a cohort of Korean atomic bomb survivors and their offspring
Hamin LEE ; Jin-Wu NAM ; Mi Kyung KIM ; Inah KIM ; Yu-Mi KIM ; Boyoung PARK
Epidemiology and Health 2024;46(1):e2024089-
The Korean Atomic Bomb Survivor Cohort (K-ABC) study was designed to investigate the health impacts of atomic bomb exposure on Korean survivors and to explore whether these effects are passed down genetically to their descendants. This paper outlines the study’s design, data collection methods, baseline socio-demographic characteristics, exposure status, and disease prevalence among the participants, based on survey responses and health examinations. From 2020 to 2024, a total of 2,544 individuals, comprising 1,109 atomic bomb survivors (G1), 1,193 children of G1 (G2), and 242 grandchildren of G1 (G3), consented to participate in the study. Of these, 1,828 participants (659 in G1, 927 in G2, and 242 in G3) completed the survey and underwent health examinations, representing a participation rate of 71.9%. Exposure information was gathered using a questionnaire and verified through records from the Korean Red Cross and a handbook issued by the Japanese government. Disease prevalence was determined based on participants’ self-reported physician diagnoses. This study presents details about the K-ABC study and provides baseline data on the participants recruited. These data will be valuable for interpreting the results of future K-ABC studies.
4.Effects of Information and Communication Technology Use on the Executive Function of Older Adults without Dementia: A Longitudinal Fixed-Effect Analysis
Hamin LEE ; Sangmi PARK ; Seungho HAN ; Hyeon Dong LEE ; Ickpyo HONG ; Hae Yean PARK
Annals of Geriatric Medicine and Research 2024;28(4):445-452
Background:
Impaired executive function is common in older adults. This study examined the causal relationship between the use of information and communication technology (ICT) and executive function in older adults over time.Method: This study performed a secondary analysis of data from four waves (2016–2019) of the National Health and Aging Trends Study. A fixed-effect analysis was conducted to examine the effects of ICT on the executive function of older adults without dementia aged ≥65 years. This study analyzed data from 3,334 respondents.
Results:
We observed significant positive effects of ICT use on executive function over time (standardized β=0.043–0.045; 95% confidence interval, 0.001–0.043; p<0.05).
Conclusion
The current findings support the use of ICT as a protective approach to prevent decline in executive function in community-dwelling older adults.
5.Cohort study profile: a cohort of Korean atomic bomb survivors and their offspring
Hamin LEE ; Jin-Wu NAM ; Mi Kyung KIM ; Inah KIM ; Yu-Mi KIM ; Boyoung PARK
Epidemiology and Health 2024;46(1):e2024089-
The Korean Atomic Bomb Survivor Cohort (K-ABC) study was designed to investigate the health impacts of atomic bomb exposure on Korean survivors and to explore whether these effects are passed down genetically to their descendants. This paper outlines the study’s design, data collection methods, baseline socio-demographic characteristics, exposure status, and disease prevalence among the participants, based on survey responses and health examinations. From 2020 to 2024, a total of 2,544 individuals, comprising 1,109 atomic bomb survivors (G1), 1,193 children of G1 (G2), and 242 grandchildren of G1 (G3), consented to participate in the study. Of these, 1,828 participants (659 in G1, 927 in G2, and 242 in G3) completed the survey and underwent health examinations, representing a participation rate of 71.9%. Exposure information was gathered using a questionnaire and verified through records from the Korean Red Cross and a handbook issued by the Japanese government. Disease prevalence was determined based on participants’ self-reported physician diagnoses. This study presents details about the K-ABC study and provides baseline data on the participants recruited. These data will be valuable for interpreting the results of future K-ABC studies.
6.Effects of Information and Communication Technology Use on the Executive Function of Older Adults without Dementia: A Longitudinal Fixed-Effect Analysis
Hamin LEE ; Sangmi PARK ; Seungho HAN ; Hyeon Dong LEE ; Ickpyo HONG ; Hae Yean PARK
Annals of Geriatric Medicine and Research 2024;28(4):445-452
Background:
Impaired executive function is common in older adults. This study examined the causal relationship between the use of information and communication technology (ICT) and executive function in older adults over time.Method: This study performed a secondary analysis of data from four waves (2016–2019) of the National Health and Aging Trends Study. A fixed-effect analysis was conducted to examine the effects of ICT on the executive function of older adults without dementia aged ≥65 years. This study analyzed data from 3,334 respondents.
Results:
We observed significant positive effects of ICT use on executive function over time (standardized β=0.043–0.045; 95% confidence interval, 0.001–0.043; p<0.05).
Conclusion
The current findings support the use of ICT as a protective approach to prevent decline in executive function in community-dwelling older adults.
7.Cohort study profile: a cohort of Korean atomic bomb survivors and their offspring
Hamin LEE ; Jin-Wu NAM ; Mi Kyung KIM ; Inah KIM ; Yu-Mi KIM ; Boyoung PARK
Epidemiology and Health 2024;46(1):e2024089-
The Korean Atomic Bomb Survivor Cohort (K-ABC) study was designed to investigate the health impacts of atomic bomb exposure on Korean survivors and to explore whether these effects are passed down genetically to their descendants. This paper outlines the study’s design, data collection methods, baseline socio-demographic characteristics, exposure status, and disease prevalence among the participants, based on survey responses and health examinations. From 2020 to 2024, a total of 2,544 individuals, comprising 1,109 atomic bomb survivors (G1), 1,193 children of G1 (G2), and 242 grandchildren of G1 (G3), consented to participate in the study. Of these, 1,828 participants (659 in G1, 927 in G2, and 242 in G3) completed the survey and underwent health examinations, representing a participation rate of 71.9%. Exposure information was gathered using a questionnaire and verified through records from the Korean Red Cross and a handbook issued by the Japanese government. Disease prevalence was determined based on participants’ self-reported physician diagnoses. This study presents details about the K-ABC study and provides baseline data on the participants recruited. These data will be valuable for interpreting the results of future K-ABC studies.
8.Social Network Typologies and Digital Literacy Differences among Korean Older Adults: A Latent Class Analysis
Hamin LEE ; Mi Kyeong KIM ; Hae Yean PARK ; Kang-Hyun PARK
Annals of Geriatric Medicine and Research 2024;28(2):134-143
Background:
This study categorized older Korean adults’ social networks and analyzed their characteristics and digital literacy differences based on type.
Methods:
We analyzed data from 9,377 Korean older adult participants of the 2020 National Survey of Older Koreans, and performed latent class analysis (LCA) chi-square and Welch’s F analyses to understand the characteristics of each social network type. The Games–Howell post-hoc test was applied to determine the significance of differences between groups.
Results:
The three social network types derived using LCA were “child-centered,” “child-friend,” and “friend-centered.” The digital literacy levels differed significantly according to social network type.
Conclusion
The results of this study can be used to propose intervention programs and services associated with older adults’ social networks by examining their social network types and the corresponding differences in digital literacy.
9.Current practice of antibiotics skin test in pediatric inpatients:A single-center experience
Yun Young ROH ; Hamin KIM ; Mireu PARK ; Soo Yeon KIM ; Jong Deok KIM ; Min Jung KIM ; Yong Ju LEE ; Yoon Hee KIM ; Kyung Won KIM ; Myung Hyun SOHN
Allergy, Asthma & Respiratory Disease 2023;11(2):77-81
Background:
Routine practice of antibiotic skin test (AST) before administering antibiotics is with little scientific basis. However, AST is frequently performed in real-world practice. We aimed to explore the current practice status of AST.
Methods:
All admission cases in Severance Hospital between January 2019 and December 2020 of patients at less than 19 years of age were collected retrospectively. AST results for 4 penicillins (ampicillin, ampicillin-sulbactam, amoxicillin-clavulanate, and piperacillin-tazobactam) and 6 cephalosporins (cefazolin, cefotaxime, cefotiam, cefpiramide, ceftriaxone, and flomoxef) as well as adverse drug reaction (ADR) reports were collected.
Results:
Among 36,381 hospitalization cases, 7,589 and 16,468 were administered penicillins and cephalosporins, respectively. Penicillins were administered without AST in 2,622 cases (35%), 2 (0.08%) of which showed ADR. Of the remaining 4,967 cases who received AST, 57 (1.1%) showed a positive reaction. For cephalosporins, 15,473 cases (94%) received antibiotics without AST. Among them, 17 cases (0.1%) showed ADRs. For 995 cases that rceived AST, 22 (2.2%) revealed a positive reaction. Among 79 cases who were AST positive, 10 took the original medication.
Conclusion
The current practice of AST reveals heterogeneous and inconsistent patterns. This brings the need for a standardized guideline for the safe and effective use of antibiotics.
10.Radiologic Assessment of Lung Edema Score as a Predictor of Clinical Outcome in Children with Acute Respiratory Distress Syndrome
Chang Hoon HAN ; Mireu PARK ; Hamin KIM ; Yun Young ROH ; Soo Yeon KIM ; Jong Deok KIM ; Min Jung KIM ; Yong Ju LEE ; Kyung Won KIM ; Yoon Hee KIM
Yonsei Medical Journal 2023;64(6):384-394
Purpose:
The radiographic assessment of lung edema (RALE) score enables objective quantification of lung edema and is a valuable prognostic marker of adult acute respiratory distress syndrome (ARDS). We aimed to evaluate the validity of RALE score in children with ARDS.
Materials and Methods:
The RALE score was measured for its reliability and correlation to other ARDS severity indices. ARDSspecific mortality was defined as death from severe pulmonary dysfunction or the need for extracorporeal membrane oxygenation therapy. The C-index of the RALE score and other ARDS severity indices were compared via survival analyses.
Results:
Among 296 children with ARDS, 88 did not survive, and there were 70 ARDS-specific non-survivors. The RALE score showed good reliability with an intraclass correlation coefficient of 0.809 [95% confidence interval (CI), 0.760–0.848]. In univariable analysis, the RALE score had a hazard ratio (HR) of 1.19 (95% CI, 1.18–3.11), and the significance was maintained in multivariable analysis adjusting with age, ARDS etiology, and comorbidity, with an HR of 1.77 (95% CI, 1.05–2.91). The RALE score was a good predictor of ARDS-specific mortality, with a C-index of 0.607 (95% CI, 0.519–0.695).
Conclusion
The RALE score is a reliable measure for ARDS severity and a useful prognostic marker of mortality in children, especially for ARDS-specific mortality. This score provides information that clinicians can use to decide the proper time of aggressive therapy targeting severe lung injury and to appropriately manage the fluid balance of children with ARDS.

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