1.Palliative Care and Hospice for Heart Failure Patients: Position Statement From the Korean Society of Heart Failure
Seung-Mok LEE ; Hae-Young LEE ; Shin Hye YOO ; Hyun-Jai CHO ; Jong-Chan YOUN ; Seong-Mi PARK ; Jin-Ok JEONG ; Min-Seok KIM ; Chi Young SHIM ; Jin Joo PARK ; Kye Hun KIM ; Eung Ju KIM ; Jeong Hoon YANG ; Jae Yeong CHO ; Sang-Ho JO ; Kyung-Kuk HWANG ; Ju-Hee LEE ; In-Cheol KIM ; Gi Beom KIM ; Jung Hyun CHOI ; Sung-Hee SHIN ; Wook-Jin CHUNG ; Seok-Min KANG ; Myeong Chan CHO ; Dae-Gyun PARK ; Byung-Su YOO
International Journal of Heart Failure 2025;7(1):32-46
Heart failure (HF) is a major cause of mortality and morbidity in South Korea, imposing substantial physical, emotional, and financial burdens on patients and society. Despite the high burden of symptom and complex care needs of HF patients, palliative care and hospice services remain underutilized in South Korea due to cultural, institutional, and knowledge-related barriers. This position statement from the Korean Society of Heart Failure emphasizes the need for integrating palliative and hospice care into HF management to improve quality of life and support holistic care for patients and their families. By clarifying the role of palliative care in HF and proposing practical referral criteria, this position statement aims to bridge the gap between HF and palliative care services in South Korea, ultimately improving patient-centered outcomes and aligning treatment with the goals and values of HF patients.
2.Comparative analysis of body mass index and obesity-related anthropometric indices for mortality prediction: a study of the Namwon and Dong-gu cohort in Korea
Ye Rim KIM ; Min-Ho SHIN ; Young-Hoon LEE ; Seong-Woo CHOI ; Hae-Sung NAM ; Jeong-Ho YANG ; Sun-Seog KWEON
Epidemiology and Health 2024;46(1):e2024066-
OBJECTIVES:
This study investigated the associations between several obesity-related anthropometric indices and mortality in middle-aged and elderly populations to compare the indices’ predictive ability with that of the body mass index (BMI).
METHODS:
We analyzed data on 12 indices calculated from 19,805 community-based cohort participants (average age, 63.27 years; median follow-up, 13.49 years). Each index was calculated using directly measured values of height, weight, waist circumference (WC), and hip circumference (HC). We calculated hazard ratios (HRs) and 95% confidence intervals (CIs) for each index using Cox regression and evaluated mortality prediction with the Harrell concordance index (c-index).
RESULTS:
Adding anthropometric indices to the basic mortality model (c-index, 0.7723; 95% CI, 0.7647 to 0.7799) significantly increased the predictive power of BMI (c-index, 0.7735; 95% CI, 0.7659 to 0.7811), a body shape index (ABSI; c-index, 0.7735; 95% CI, 0.7659 to 0.7810), weight-adjusted waist index (WWI; c-index, 0.7731; 95% CI, 0.7656 to 0.7807), and waist to hip index (WHI; c-index, 0.7733; 95% CI, 0.7657 to 0.7809). The differences between the BMI model and the other 3 models were not statistically significant.
CONCLUSIONS
In predicting all-cause mortality, the ABSI, WWI, and WHI models based on WC or HC had stronger predictive power than conventional risk factors but were not significantly different from the BMI model.
3.Cohort profile: Multicenter Networks for Ideal Outcomes of Rare Pediatric Endocrine and Metabolic Diseases in Korea (OUTSPREAD study)
Yun Jeong LEE ; Chong Kun CHEON ; Junghwan SUH ; Jung-Eun MOON ; Moon Bae AHN ; Seong Hwan CHANG ; Jieun LEE ; Jin Ho CHOI ; Minsun KIM ; Han Hyuk LIM ; Jaehyun KIM ; Shin-Hye KIM ; Hae Sang LEE ; Yena LEE ; Eungu KANG ; Se Young KIM ; Yong Hee HONG ; Seung YANG ; Heon-Seok HAN ; Sochung CHUNG ; Won Kyoung CHO ; Eun Young KIM ; Jin Kyung KIM ; Kye Shik SHIM ; Eun-Gyong YOO ; Hae Soon KIM ; Aram YANG ; Sejin KIM ; Hyo-Kyoung NAM ; Sung Yoon CHO ; Young Ah LEE
Annals of Pediatric Endocrinology & Metabolism 2024;29(6):349-355
Rare endocrine diseases are complex conditions that require lifelong specialized care due to their chronic nature and associated long-term complications. In Korea, a lack of nationwide data on clinical practice and outcomes has limited progress in patient care. Therefore, the Multicenter Networks for Ideal Outcomes of Pediatric Rare Endocrine and Metabolic Disease (OUTSPREAD) study was initiated. This study involves 30 centers across Korea. The study aims to improve the long-term prognosis of Korean patients with rare endocrine diseases by collecting comprehensive clinical data, biospecimens, and patient-reported outcomes to identify complications and unmet needs in patient care. Patients with childhood-onset pituitary, adrenal, or gonadal disorders, such as craniopharyngioma, congenital adrenal hyperplasia (CAH), and Turner syndrome were prioritized. The planned enrollment is 1,300 patients during the first study phase (2022–2024). Clinical, biochemical, and imaging data from diagnosis, treatment, and follow-up during 1980–2023 were retrospectively reviewed. For patients who agreed to participate in the prospective cohort, clinical data and biospecimens will be prospectively collected to discover ideal biomarkers that predict the effectiveness of disease control measures and prognosis. Patient-reported outcomes, including quality of life and depression scales, will be evaluated to assess psychosocial outcomes. Additionally, a substudy on CAH patients will develop a steroid hormone profiling method using liquid chromatography-tandem mass spectrometry to improve diagnosis and monitoring of treatment outcomes. This study will address unmet clinical needs by discovering ideal biomarkers, introducing evidence-based treatment guidelines, and ultimately improving long-term outcomes in the areas of rare endocrine and metabolic diseases.
4.Development of the Korean Quality Improvement Platform in Surgery (K-QIPS) program: a nationwide project to improve surgical quality and patient safety
Jeong-Moo LEE ; In Woong HAN ; Oh Chul KWON ; Hye Rim SEO ; Jipmin JUNG ; So Jeong YOON ; Ahram HAN ; Juhan LEE ; Soo Young LEE ; Hoseok SEO ; Wooil KWON ; Bang Wool EOM ; In-Seob LEE ; Ji Won PARK ; Hae Won LEE ; Ho Kyoung HWANG ; Suk-Hwan LEE ; Eung Jin SHIN ; Woo Yong LEE
Annals of Surgical Treatment and Research 2024;107(6):305-314
Purpose:
Improvements in surgical quality and patient safety are critical components of the healthcare system. Despite excellent cancer survival rates in Korea, there is a lack of standardized postoperative complication management systems.To address this gap, the Korean Surgical Society initiated the development of the Korean Quality Improvement Platform in Surgery (K-QIPS) program.
Methods:
K-QIPS was successfully launched in 87 general hospitals. This nationwide surgical quality improvement program covers 5 major surgical fields: gastric surgery, colorectal surgery, hepatectomy and liver transplantation, pancreatectomy, and kidney transplantation.
Results:
Common and surgery-specific complication platforms will be developed, and the program will work toward the implementation of an artificial intelligence-based complication prediction system and the provision of evidence-based feedback to participating institutions. K-QIPS represents a significant step toward improving surgical quality and patient safety in Korea.
Conclusion
This program aims to reduce postoperative complications, mortality, and medical costs by providing a standardized platform for complication management and prediction. The successful implementation of this nationwide project may provide a good model for other countries that are required to improve surgical outcomes and patient care.
5.Surgical Outcomes of Unilateral One-muscle Surgery in Basic Intermittent Exotropia with Larger Near Deviation
Seung Hyeon LEE ; Shin Hae PARK ; Young Chun LEE
Journal of the Korean Ophthalmological Society 2024;65(11):724-730
Purpose:
To compare the postoperative changes between unilateral medial rectus resection and lateral rectus recession and evaluate surgical outcomes of unilateral one-muscle surgery in basic intermittent exotropia under 25 prism diopters (PD) with a larger near than distance deviation.
Methods:
This study was conducted on patients with basic intermittent exotropia under 25 PD and a larger near than distance deviation. A retrospective analysis was conducted on 23 patients who underwent unilateral medial rectus resection (Group 1) and 32 patients who underwent unilateral lateral rectus recession (Group 2) as primary surgery. The angle of deviation at near and distance was measured at 1 week, 1 month, 3 months, 6 months, and 1 year postoperatively. Surgical success was defined as within 4 PD of esophoria or 10 PD of exophoria at 1 year after surgery.
Results:
The mean preoperative deviation angle was 20.18 ± 2.55 PD for Group 1 and 19.30 ± 2.77 PD for Group 2, while the mean near-distance disparity was 6.83 ± 2.67 PD for Group 1 and 5.18 ± 1.56 PD for Group 2. At 1 year postoperatively, the mean distance deviation angle was 9.43 ± 5.82 PD for Group 1 and 5.94 ± 6.49 PD for Group 2. The mean near-distance disparity at 1 year was 0.91 ± 3.96 PD for Group 1 and 0.81 ± 2.07 PD for Group 2. The success rates at 1 year were 65.2% for Group 1 and 72.7% for Group 2 (p = 0.362). Both groups showed effective reductions in the postoperative angle of deviation and near-distance disparity with no significant difference between the groups.
Conclusions
Unilateral medial rectus resection and lateral rectus recession both effectively manage basic intermittent exotropia under 25 PD with larger near than distance deviation as the primary surgery.
6.Comparative analysis of body mass index and obesity-related anthropometric indices for mortality prediction: a study of the Namwon and Dong-gu cohort in Korea
Ye Rim KIM ; Min-Ho SHIN ; Young-Hoon LEE ; Seong-Woo CHOI ; Hae-Sung NAM ; Jeong-Ho YANG ; Sun-Seog KWEON
Epidemiology and Health 2024;46(1):e2024066-
OBJECTIVES:
This study investigated the associations between several obesity-related anthropometric indices and mortality in middle-aged and elderly populations to compare the indices’ predictive ability with that of the body mass index (BMI).
METHODS:
We analyzed data on 12 indices calculated from 19,805 community-based cohort participants (average age, 63.27 years; median follow-up, 13.49 years). Each index was calculated using directly measured values of height, weight, waist circumference (WC), and hip circumference (HC). We calculated hazard ratios (HRs) and 95% confidence intervals (CIs) for each index using Cox regression and evaluated mortality prediction with the Harrell concordance index (c-index).
RESULTS:
Adding anthropometric indices to the basic mortality model (c-index, 0.7723; 95% CI, 0.7647 to 0.7799) significantly increased the predictive power of BMI (c-index, 0.7735; 95% CI, 0.7659 to 0.7811), a body shape index (ABSI; c-index, 0.7735; 95% CI, 0.7659 to 0.7810), weight-adjusted waist index (WWI; c-index, 0.7731; 95% CI, 0.7656 to 0.7807), and waist to hip index (WHI; c-index, 0.7733; 95% CI, 0.7657 to 0.7809). The differences between the BMI model and the other 3 models were not statistically significant.
CONCLUSIONS
In predicting all-cause mortality, the ABSI, WWI, and WHI models based on WC or HC had stronger predictive power than conventional risk factors but were not significantly different from the BMI model.
7.Cohort profile: Multicenter Networks for Ideal Outcomes of Rare Pediatric Endocrine and Metabolic Diseases in Korea (OUTSPREAD study)
Yun Jeong LEE ; Chong Kun CHEON ; Junghwan SUH ; Jung-Eun MOON ; Moon Bae AHN ; Seong Hwan CHANG ; Jieun LEE ; Jin Ho CHOI ; Minsun KIM ; Han Hyuk LIM ; Jaehyun KIM ; Shin-Hye KIM ; Hae Sang LEE ; Yena LEE ; Eungu KANG ; Se Young KIM ; Yong Hee HONG ; Seung YANG ; Heon-Seok HAN ; Sochung CHUNG ; Won Kyoung CHO ; Eun Young KIM ; Jin Kyung KIM ; Kye Shik SHIM ; Eun-Gyong YOO ; Hae Soon KIM ; Aram YANG ; Sejin KIM ; Hyo-Kyoung NAM ; Sung Yoon CHO ; Young Ah LEE
Annals of Pediatric Endocrinology & Metabolism 2024;29(6):349-355
Rare endocrine diseases are complex conditions that require lifelong specialized care due to their chronic nature and associated long-term complications. In Korea, a lack of nationwide data on clinical practice and outcomes has limited progress in patient care. Therefore, the Multicenter Networks for Ideal Outcomes of Pediatric Rare Endocrine and Metabolic Disease (OUTSPREAD) study was initiated. This study involves 30 centers across Korea. The study aims to improve the long-term prognosis of Korean patients with rare endocrine diseases by collecting comprehensive clinical data, biospecimens, and patient-reported outcomes to identify complications and unmet needs in patient care. Patients with childhood-onset pituitary, adrenal, or gonadal disorders, such as craniopharyngioma, congenital adrenal hyperplasia (CAH), and Turner syndrome were prioritized. The planned enrollment is 1,300 patients during the first study phase (2022–2024). Clinical, biochemical, and imaging data from diagnosis, treatment, and follow-up during 1980–2023 were retrospectively reviewed. For patients who agreed to participate in the prospective cohort, clinical data and biospecimens will be prospectively collected to discover ideal biomarkers that predict the effectiveness of disease control measures and prognosis. Patient-reported outcomes, including quality of life and depression scales, will be evaluated to assess psychosocial outcomes. Additionally, a substudy on CAH patients will develop a steroid hormone profiling method using liquid chromatography-tandem mass spectrometry to improve diagnosis and monitoring of treatment outcomes. This study will address unmet clinical needs by discovering ideal biomarkers, introducing evidence-based treatment guidelines, and ultimately improving long-term outcomes in the areas of rare endocrine and metabolic diseases.
8.Development of the Korean Quality Improvement Platform in Surgery (K-QIPS) program: a nationwide project to improve surgical quality and patient safety
Jeong-Moo LEE ; In Woong HAN ; Oh Chul KWON ; Hye Rim SEO ; Jipmin JUNG ; So Jeong YOON ; Ahram HAN ; Juhan LEE ; Soo Young LEE ; Hoseok SEO ; Wooil KWON ; Bang Wool EOM ; In-Seob LEE ; Ji Won PARK ; Hae Won LEE ; Ho Kyoung HWANG ; Suk-Hwan LEE ; Eung Jin SHIN ; Woo Yong LEE
Annals of Surgical Treatment and Research 2024;107(6):305-314
Purpose:
Improvements in surgical quality and patient safety are critical components of the healthcare system. Despite excellent cancer survival rates in Korea, there is a lack of standardized postoperative complication management systems.To address this gap, the Korean Surgical Society initiated the development of the Korean Quality Improvement Platform in Surgery (K-QIPS) program.
Methods:
K-QIPS was successfully launched in 87 general hospitals. This nationwide surgical quality improvement program covers 5 major surgical fields: gastric surgery, colorectal surgery, hepatectomy and liver transplantation, pancreatectomy, and kidney transplantation.
Results:
Common and surgery-specific complication platforms will be developed, and the program will work toward the implementation of an artificial intelligence-based complication prediction system and the provision of evidence-based feedback to participating institutions. K-QIPS represents a significant step toward improving surgical quality and patient safety in Korea.
Conclusion
This program aims to reduce postoperative complications, mortality, and medical costs by providing a standardized platform for complication management and prediction. The successful implementation of this nationwide project may provide a good model for other countries that are required to improve surgical outcomes and patient care.
9.Comparative analysis of body mass index and obesity-related anthropometric indices for mortality prediction: a study of the Namwon and Dong-gu cohort in Korea
Ye Rim KIM ; Min-Ho SHIN ; Young-Hoon LEE ; Seong-Woo CHOI ; Hae-Sung NAM ; Jeong-Ho YANG ; Sun-Seog KWEON
Epidemiology and Health 2024;46(1):e2024066-
OBJECTIVES:
This study investigated the associations between several obesity-related anthropometric indices and mortality in middle-aged and elderly populations to compare the indices’ predictive ability with that of the body mass index (BMI).
METHODS:
We analyzed data on 12 indices calculated from 19,805 community-based cohort participants (average age, 63.27 years; median follow-up, 13.49 years). Each index was calculated using directly measured values of height, weight, waist circumference (WC), and hip circumference (HC). We calculated hazard ratios (HRs) and 95% confidence intervals (CIs) for each index using Cox regression and evaluated mortality prediction with the Harrell concordance index (c-index).
RESULTS:
Adding anthropometric indices to the basic mortality model (c-index, 0.7723; 95% CI, 0.7647 to 0.7799) significantly increased the predictive power of BMI (c-index, 0.7735; 95% CI, 0.7659 to 0.7811), a body shape index (ABSI; c-index, 0.7735; 95% CI, 0.7659 to 0.7810), weight-adjusted waist index (WWI; c-index, 0.7731; 95% CI, 0.7656 to 0.7807), and waist to hip index (WHI; c-index, 0.7733; 95% CI, 0.7657 to 0.7809). The differences between the BMI model and the other 3 models were not statistically significant.
CONCLUSIONS
In predicting all-cause mortality, the ABSI, WWI, and WHI models based on WC or HC had stronger predictive power than conventional risk factors but were not significantly different from the BMI model.
10.Surgical Outcomes of Unilateral One-muscle Surgery in Basic Intermittent Exotropia with Larger Near Deviation
Seung Hyeon LEE ; Shin Hae PARK ; Young Chun LEE
Journal of the Korean Ophthalmological Society 2024;65(11):724-730
Purpose:
To compare the postoperative changes between unilateral medial rectus resection and lateral rectus recession and evaluate surgical outcomes of unilateral one-muscle surgery in basic intermittent exotropia under 25 prism diopters (PD) with a larger near than distance deviation.
Methods:
This study was conducted on patients with basic intermittent exotropia under 25 PD and a larger near than distance deviation. A retrospective analysis was conducted on 23 patients who underwent unilateral medial rectus resection (Group 1) and 32 patients who underwent unilateral lateral rectus recession (Group 2) as primary surgery. The angle of deviation at near and distance was measured at 1 week, 1 month, 3 months, 6 months, and 1 year postoperatively. Surgical success was defined as within 4 PD of esophoria or 10 PD of exophoria at 1 year after surgery.
Results:
The mean preoperative deviation angle was 20.18 ± 2.55 PD for Group 1 and 19.30 ± 2.77 PD for Group 2, while the mean near-distance disparity was 6.83 ± 2.67 PD for Group 1 and 5.18 ± 1.56 PD for Group 2. At 1 year postoperatively, the mean distance deviation angle was 9.43 ± 5.82 PD for Group 1 and 5.94 ± 6.49 PD for Group 2. The mean near-distance disparity at 1 year was 0.91 ± 3.96 PD for Group 1 and 0.81 ± 2.07 PD for Group 2. The success rates at 1 year were 65.2% for Group 1 and 72.7% for Group 2 (p = 0.362). Both groups showed effective reductions in the postoperative angle of deviation and near-distance disparity with no significant difference between the groups.
Conclusions
Unilateral medial rectus resection and lateral rectus recession both effectively manage basic intermittent exotropia under 25 PD with larger near than distance deviation as the primary surgery.

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